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Eksakta : Berkala Ilmiah Bidang MIPA
Published by Universitas Negeri Padang
ISSN : -     EISSN : 25497464     DOI : https://doi.org/10.24036/eksakta/
Core Subject : Science, Education, Agriculture, Social, Engineering,
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Energy Engineering Environmental Science Materials Science & Nanotechnology Mathematics Mechanical Engineering
Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464) is an open access journal and peer-reviewed that publishes either original article or reviews. The journal is dedicated towards dissemination of knowledge related to the advancement in scientific research. The prestigious interdisciplinary editorial board reflects the diversity of subjects covered in this journal. Under the realm of science and technology, the coverage includes environmental science, pure and applied mathematics, agricultural research and engineering, biology, biotechnology, bioinformatics, Healthcare sciences (including clinical medicine, preventive medicine & public health), physics, biophysics, computer science, chemistry and bioengineering, to name a few. This Journal Is Published at 3 Month intervals on January-Marc, April-June, July-September and October-December
Arjuna Subject : Umum - Umum
Articles 310 Documents
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Third-Generation cephalosporins (3GC) and Fluoroquinolones (FQ) Co-Resistance in Extended-Spectrum Beta-Lactamase-Producing Escherichia coli (ESBL-Ec) from Clinical and Community Isolates Febrianti, Tati; Puspandari, Nelly; Karuniawati, Anis
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 24 No. 04 (2023): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol23-iss04/462

Abstract

The growing AMR issue affects the current antimicrobial therapy recommendations, particularly for broad-spectrum antibiotics, like third-generation cephalosporins (3GC) and fluoroquinolones (FQ). Actually, the inappropriate use of both antibiotics in clinical and community settings increase the resistance of extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-Ec). Although ESBL-Ec is used as a surveillance indicator of bacterial resistance, but currently studies related to 3GC-FQ co-resistance among clinical and community (including human and wastewater samples) based ESBL-Ec isolation, have not been widely carried out. The objective of this study was to analyze the possibility and mechanism of 3GC-FQ co-resistance among ESBL-Ec, in human clinical and communal isolates from previous published research. Out of 257 articles screened, four studies in accordance with our study are included in the analysis. The result indicated that ESBL-Ec derived from all sample sources had 3GC-FQ co-resistance. According to two studies reviewed, blaCTX-M was the most predominant ESBL gene, while the FQ-associated resistant gene dominated by qnr family genes. Resistant genes and co-resistant ESBL-Ec can be spread rapidly through plasmids.
Estimation of Phytoplankton Density in Waters Kampar River Kampar District Dinata, Marta; Sembiring, Al Khudri; Ramadansur, Rahmat
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 25 No. 03 (2024): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol25-iss03/341

Abstract

The Kampar River is one of the rivers in the upper reaches that has caused pollution due to local communities such as excessive activity and gravel and sand mining. The purpose of this study was to determine the density of phytoplankton in the Kampar River in Koto Kampar Hulu Subdistrict, Kampar Regency. Purposive sampling was used to determine observation stations, which took into account habitat types and biological parameters observed such as species composition, abundance, and diversity index. The findings revealed that five classes of algae were discovered in Kampar Chlorophyceae, Cyanophyceae, Zygnematophyceae, Bacillariophyceae, and Xanthophyceae. The abundance of phytoplankton in the Kampar River's waters is classified as moderate fertility, ranging from 2,419.96 cells/liter to 3,629.96 cells/liter.
Solving Partial Differential Equations for Wave Equation Problem on Strings by Applying the Fourier Transform Amelia; Rusyaman, Endang; Kusuma, Dianne Amor; Azril
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 24 No. 04 (2023): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol23-iss04/346

Abstract

The wave equation on a string is an example of a partial differential equation problem. There are several methods for finding the solution to the wave equation on a string. The solution method will differ depending on definition of the function's domain. This study aims to determine the form of solving the wave equation on the strings and the results of the analysis of the wave motion that depends on the number of boundary conditions, using a particular solution method, namely the Fourier transform method. The boundary conditions used are Dirichlet boundary conditions. The Fourier transform method is used to obtain the solution of the wave equation on the string. The Fourier transform will transform the wave equation on the string and get the solution form of the wave equation on the string by applying the inverse Fourier transform. The results of this study obtained the same form of solution for each state from the wave equation on strings, namely in the form of the D'Alembert solution for the wave equation. As well, the movement of the wave will form a periodic solution by period , with a different form of deviation occurring at each point  for each value .
Evaluation of User Satisfaction and Loyalty of Sports News Portal Application Using Technology Acceptance Model Saputra, Roy Inzaqhi; Haryamadha, Rama; Nuryasin, Ilyas
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 25 No. 03 (2024): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol25-iss03/352

Abstract

Current technological advances have created gaps in people's ability to obtain information quickly. It was as if the strenuous efforts of people wanting to know more about what had happened had broken down the information barrier. This research is included in the category of quantitative descriptive research. This research is focused on news portal application users. The sampling technique used in this study was random sampling, with a total sample of 100 participants. This research uses PLS data analysis technique with SEM approach model. The results showed that perceived ease of use affects mobile user satisfaction. Perceived usefullness affects mobile user satisfaction. Trust affects mobile user satisfaction. Convencience affects mobile user satisfaction. Security affects mobile user satisfaction. Perceived ease of use does not affect user loyalty. Perceived usefullness affects user loyalty. Trust affects user loyalty. Convencience affects user loyalty. Security affects user loyalty.
Classification of Covid-19 Vaccine Sentiment Using K-Nearest Neighbor and Fasttext on Twitter Safrizal, Afri Naldi; Surya Agustian
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 25 No. 03 (2024): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol25-iss03/384

Abstract

 In late 2019 came a flu-like illness that infected the lungs in the city of Wuhan. It is suspected that the disease is suspected to have originated in bats. WHO named this disease Covid-19 and the virus spread throughout the world, causing a pandemic. The government took a vaccination drive to overcome this virus, but received a response of pros and cons from the public. There are many studies that discuss people's sentiments towards vaccination, one of which is the classification of sentiments. This study discusses the classification of sentiment towards covid-19 vaccines using the K-Nearest Neighbor and Fasttext algorithms on twitter. Data is obtained by crawling using the pyton programming language and Twitter API.  Data labeling is carried out by crowdsourcing and majority voting techniques.  The data used after the balancing process are 6000 training data, 778 development data and 400 test data.  The test results after various experiments and feature engineering got the best results with an accuracy value of 69% and an f1-score of 60%. This result is the best result compared to previous studies with the same dataset.
Investigating the Efficacy of Ginger and Lemon Boiled Water: A New Approach to Treating Mild Hyperemesis Gravidarum in Pregnant Women Evitasari, Desi; Amalia, Merlly; Suyanti, Suyanti; Listiani, Imas; Purnamasari, Devi; Po Yuan Wang; Juan Anthonio
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 25 No. 01 (2024): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol25-iss01/388

Abstract

In a quasi-experimental study, we investigated the impact of ginger and lemon boiled water on level 1 hyperemesis gravidarum in pregnant women. Utilizing a one-group pretest-posttest design, the study involved 20 participants who reported experiencing severe hyperemesis gravidarum symptoms. Following the intervention, the incidence of severe symptoms was reduced to zero among the participants. Statistical analysis with the Wilcoxon signed-rank test revealed a significant reduction in symptoms (p=0.001), indicating the potential of ginger and lemon boiled water as an effective non-pharmacological remedy for nausea and vomiting in pregnancy. These results advocate for the inclusion of alternative therapies in health education for pregnant women and highlight the necessity of seeking professional healthcare advice when experiencing such symptoms.
Molecular Docking of ftsZ Protein of Staphylococcus aureus to Indonesian Herbal Compound Monica, Maria Diyan; Erlina, Linda; Fadilah, Fadilah; Paramita, Rafika Indah
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 25 No. 01 (2024): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol25-iss01/431

Abstract

Microbial resistance to antibiotics is a growing global problem, and new antibacterial agents are needed to overcome this. One of the bacteria with a high level of resistance is Staphylococcus aureus. Herbal compounds are an alternative as a source of new antibacterial agents. Molecular docking can be used in screening herbal compounds that can become new antibacterial agents against Staphylococcus aureus. Virtual screening was conducted using Ligandscout, and molecular docking was conducted via Autodock. LigPlot was used to analyze the interaction between hit compounds to the protein target, and finally, the pharmacokinetic characteristics were assessed in SWISSADME and ADMETsar programs. From 1377 compounds in the Indonesian Herbal Database, 12 hit compounds have an affinity to the target protein ftsZ of Staphylococcus aureus. Further analysis of the interaction with target protein and pharmacokinetics properties considers Alpha Santalol a compound with good potential for further development as an antibacterial agent against Staphylococcus aureus. However, in vitro and in vivo study is needed to validate this result.
Analysis of The Effect of Soundproofing on Ship Engines Based on Composite Materials Made from Tofu Dregs (Glycine Max L Merill) Aurista Miftahatul Ilmah; Anauta Lungiding Angga Risdianto; Belgis Risky Wijaya; Arief Syarifuddin; Triyanti Irmiyana; Taufan Prasetyo; Muhammad Arus Samudera; Mohammad Hamid
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 25 No. 03 (2024): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol25-iss03/436

Abstract

Minimizing ship noise and vibrations is crucial due to  potentially severe consequences, such as communication problems, sleep disturbances, stress, and structural damage. To address this, effective dampers are necessary. Many soundproofing materials now utilize natural fiber waste to replace synthetic materials, which are harmful to environment. One underutilized natural fiber is tofu dregs, which contain fibers suitable for sound absorption. This study investigates using tofu dregs as a composite material in sound-dampening applications. Composites are materials engineered from two or more substances with different properties to create a heterogeneous mixture. In this research, sound-dampening composites were developed using tofu dregs combined with carbon black and talc duco. The study found that the composite containing 60 grams of tofu dregs, 60 grams of talc duco, and 50 grams of resin achieved a sound absorption coefficient of α = 0.19. Meanwhile, the composite with 60 grams of tofu dregs, 50 grams of carbon black, and 50 grams of resin achieved a higher sound absorption coefficient of α = 0.24. These results indicate that the tofu dregs and carbon black composite offer superior sound absorption compared to tofu dregs and talc duco composite, demonstrating potential of tofu dregs as an eco-friendly soundproofing material.
Identification of Active Compounds of Leaf Extract and Seed Oil of Moringa oleifera in TrkB Receptor as Neuroprotective by Molecular Docking Muhamad Sadam Safutra; Fadilah; Wawaimuli Arozal; Agian Jeffilano Barinda
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 25 No. 02 (2024): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol25-iss02/442

Abstract

The functional ability of the brain will decline progressively during aging which usually involves changes in plasticity. BDNF is one of the neurotrophins that regulates plasticity via TrkB receptors. So the potential of Moringa oleifera leaf and seed oil extracts was identified as neuroprotective on the interaction of TrkB receptors with molecular docking. The active compounds of Moringa oleifera leaf extract and seed oil were obtained from literature studies. Drug-likeness and ADMETox analysis were carried out using the SwissAdme and the AdmetSAR webserver. The molecular docking was carried out using the Pyrx Vina application and visualization is done using the Discovery Studio Biovia application. The docking results showed the best compounds namely luteolin, stigmasterol, and moringin as a marker compound and showed the interaction of hydrogen and hydrophobic bonds at the active site of the prediction results. So it can be concluded that compounds in the leaves and seed oil of Moringa oleifera, namely luteolin, stigmasterol, and moringin are predicted as ingredients that can activate TrkB receptors in the aging process.
Phyrochemical Screening and Potential Inhibition of Pacing Extract (Costus speciousus, J.Sm) Against Mycobacterium Tuberculosis H37Rv Puspaningtyas, Ayik Rosita; Rumaikewi, Carolin Enjelin; Sari, Indah Purnama
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 25 No. 03 (2024): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol25-iss03/451

Abstract

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (Mtb) and can attack various organs of the body. Transmission occurs through sputum splashes when coughing, sneezing or talking. TB treatment using antituberculosis drugs (OAT) can cause side effects that affect health. Therefore, alternative therapies from natural ingredients are needed. This study aims to explore secondary metabolites in extracts and plant fractions of Pacing (Costus speciousus, J.Sm) and determine their effectiveness against Mycobacterium tuberculosis H37Rv. The extraction method used is remaceration with methanol solvent. The concentrations of the samples tested varied with isoniazid positive controls. The results showed that Pacing plant extracts and fractions contained alkaloids, flavonoids, saponins, and tannins. Terpenoid compounds were not detected in the samples tested. The antituberculosis test showed that the n-hexane fraction had the best anti-TB activity, although the IC50 value of the extract and fraction was still lower than isoniazid as a positive control. However, Pacing extract and fraction still have potential as very strong anti-TB agents because their IC50 values ​​are below 50 ppm.

Page 23 of 31 | Total Record : 310

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