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Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua Jalan Besar Deli Tua No. 77, Kabupaten Deli Serdang, Sumatera- Utara
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Jurnal Penelitian Farmasi dan Herbal
Published by INSTITUT KESEHATAN DELI HUSADA DELI TUA
ISSN : -     EISSN : 26547619     DOI : 10.36656/jpfh
Core Subject : Health,
Medicine & Pharmacology
Aims and Scope The Pharmaceutical & Herb Research Journal is a scientific journal published by Institut Kesehatan Deli Husada which publishes research journals in the field of pharmacy. Indonesia has a lot of natural resources that have the potential to have pharmacological effects. This journal is a place for researchers in the field of pharmacy to be able to publish their researches in 2 main areas, namely Pharmacy and Herbs In the Pharmacy area, accepted research articles include: • Pharmaceutical Biology • Pharmaceutical Chemistry • Pharmacology • Pharmaceutical Technology While the Herb area includes • Herb medicinal formulations from natural ingredients The Pharmaceutical & Herb Research Journal can also be a forum for informations and sources of knowledge related to the field of pharmaceutical science and herb medicine in Indonesia.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 193 Documents
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The PHARMACY AND ARCHIPELAGO CON PHARMACY AND ARCHIPELAGO CONSTITUTIONAL THEORY: PHARMACY AS GUARDIAN OF ETHICAL AND LOCAL LEGAL BALANCE Dita, Rahma Dita; Sudrajat, Hendra
Jurnal Penelitian Farmasi Dan Herbal Vol 8 No 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2512

Abstract

This article explores the role of pharmacists as ethical and legal mediators within pluralistic legal systems in Indonesia. Informed by the theory of Konstitusi Nusantara (Nusantara Constitution), this study frames the pharmacist not merely as a medical professional but as a guardian of balance between local customs and national regulations. Using a qualitative normative-juridical method and interdisciplinary analysis across pharmaceutical sciences, constitutional law, and health anthropology, this research draws from literature and regional practices in Papua, Kalimantan, and Nusa Tenggara. Findings show that pharmacists often navigate overlapping norms professional codes, state law, and local customary systems especially when working within indigenous communities. Their unique position enables them to build culturally respectful communication, advocate for the safe use of traditional remedies, and promote ethical healthcare grounded in local wisdom. The study calls for curricular reform in pharmacy education that integrates local legal-cultural knowledge and for policies that institutionalize collaboration between pharmacists and customary authorities. This research provides conceptual and practical insights for building inclusive, locally rooted healthcare governance in Indonesia. Keywords: Pharmacist, Local wisdom, Legal pluralism, Indigenous health
The Antibacterial Activity of Ethanol Extract, n-Hexane Fraction, and Ethyl Acetate Fraction of Water Hyacinth Leaves (Eichhornia crassipes) Growing on the Banks of the Mahakam River Against Propionibacterium acnes dewi, herlina ekapratama; Cahya, Muhammad Dwi Cahya; Pratiwi, Putri Rinda
Jurnal Penelitian Farmasi Dan Herbal Vol 8 No 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2595

Abstract

Propionibacterium acnes is a gram-positive bacterium that causes acne. Water hyacinth (Eichhornia crassipes) is a plant commonly found along the banks of the Mahakam River that has antibacterial properties. The purpose of this study was to perform a phytochemical screening and determine the antibacterial activity of the ethanol extract, n-hexane fraction, and ethyl acetate fraction of water hyacinth (Eichhornia crassipes) leaves against Propionibacterium acnes bacteria. Antibacterial activity was measured by the diameter of the inhibition zone using the agar diffusion method. Phytochemical screening results showed that the ethanol extract and ethyl acetate fraction of water hyacinth leaves were positive for flavonoids, alkaloids, and tannins, while these metabolites were not found in the n-hexane fraction. Each test solution was prepared at concentrations of 5%, 7.5%, 15%, and 30%. The antibacterial activity test yielded average inhibition zone diameters for the ethanol extract, n-hexane fraction, and ethyl acetate fraction of 12.70 mm, 12.85 mm, and 13.17 mm, respectively.
FORMULASI DAN UJI STABILITAS FISIK SERTA PENENTUAN NILAI SPF (Sun Protecting Factor) GEL MOISTURIZER EKSTRAK ETANOL DAUN KELAKAI (Stenochlaena Palustris (BURM. F.) Bedd.) Sembiring, Pintata
Jurnal Penelitian Farmasi Dan Herbal Vol 8 No 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2605

Abstract

Flavonoids in kelakai (Stenochlaena palustris) leaves function as powerful antioxidants that increase skin protection against UV radiation through absorption and scattering of ultraviolet rays. The presence of chromophore groups in the form of conjugated double bonds in flavonoids is able to absorb UVB rays so as to reduce their intensity on the skin and contribute to increasing the Sun Protection Factor (SPF) value of the moisturizer gel. This allows the product to function as a moisturizer as well as a natural plant-based sunscreen. This research aims to formulate kelakai leaf extract moisturizer gel, eval_uate its physical stability, and measure the SPF value. The extract was obtained through maceration, then made into moisturizer gel with concentrations of 3% (F1), 5% (F2), and 7% (F3). For four weeks, organoleptic, homogeneity, spreadability, pH, stability, viscosity, and centrifugation tests were conducted. The results showed that all formulas were homogeneous, brownish yellow (F1), light brown (F2), and dark brown (F3) in color; spreadability 5.39-6.20 cm; pH 5.07-5.96; stable at room temperature and cold; viscosity 6192-7108 cPs; and no phase separation. In vitro SPF measurements using a UV-Vis spectrophotometer at a wavelength of 290-320 nm showed the highest SPF value in F3 (7% extract) of 27.51, while F1 and F2 were 18.49 and 21.94 respectively, so that the three formulas can provide optimal protection from UV rays.
eval_uasi Penggunaan Antibiotik Profilaksis pada Pasien Bedah Caesar dengan Menggunakan Metode Gyssens di Rumah Sakit X Mojokerto Amanda, Cantika Putri
Jurnal Penelitian Farmasi Dan Herbal Vol 8 No 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2608

Abstract

Introduction: Delivery is a physiological process of expelling the fetus and placenta from the uterus, either spontaneously through the vagina or through operative procedures such as cesarean section. Cesarean section has become one of the commonly performed methods of delivery, but it carries a higher risk of surgical wound infections compared to normal delivery. The use of prophylactic antibiotics is important to prevent such complications; however, in practice, it often does not conform to guidelines, which can reduce the effectiveness of infection prevention and trigger antibiotic resistance. Objective: To assess the rationality of prophylactic antibiotic use in cesarean section patients at Hospital X in Mojokerto. Method: This study employs a descriptive observational method with a retrospective approach. Data was collected from 87 medical records of cesarean section patients during the period of 2024–2025. The eval_uation of prophylactic antibiotic use was conducted based on the Gyssens method to assess the accuracy of diagnosis, indications, drug selection, dosage, route and interval of administration, as well as the duration of therapy. Results: The majority of patients (92%) received prophylactic antibiotics rationally (Gyssens category 0). A small number of patients fall into category IIa (5%) due to dose inaccuracies, and category IVd (3%) with the use of broad-spectrum antibiotics. Conclusion: The use of prophylactic antibiotics in cesarean section patients at Hospital X Mojokerto is mostly rational (92%), while (8%) is irrational.
PENETAPAN KADAR DIETILEN GLIKOL (DEG) PADA SIRUP ANAK YANG BEREDAR DI APOTEK DENGAN METODE SPEKTROFOTOMETRI UV-VIS sulasmi, sulasmi
Jurnal Penelitian Farmasi Dan Herbal Vol 8 No 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2703

Abstract

Penelitian ini bertujuan untuk menetapkan kadar dietilen glikol (DEG) pada sirup anak yang beredar di apotek menggunakan metode spektrofotometri UV-Vis, sekaligus memvalidasi metode tersebut. DEG dikategorikan sebagai zat berbahaya yang dapat menyebabkan gagal ginjal akut, dengan batas aman tidak boleh melebihi 0,1%. Sampel diambil secara purposive sampling dari tiga merek sirup yang paling banyak dibeli di Apotek Deli Tua. Hasil penelitian menunjukkan panjang gelombang maksimum DEG adalah 625 nm , dengan operating time optimal 15 menit. Kurva kalibrasi menunjukkan linearitas tinggi (R2=0,999). Kadar rata-rata DEG pada sampel A, B, dan C berturut-turut adalah 0,08756%, 0,16138%, dan 0,1334%. Dua dari tiga sampel tersebut melebihi ambang batas aman 0,1% yang ditetapkan BPOM, mengindikasikan potensi risiko kesehatan. Validasi metode menunjukkan akurasi (80-120% recovery) dan presisi (%RSD < 2%) yang baik. Oleh karena itu, penelitian lanjutan dengan metode analisis lain dan analisis toksikologis direkomendasikan.
FORMULASI DAN UJI KETAHANAN SEDIAAN PARFUM SPRAY BUNGA LILI ( Lilium longiflorum) Simorangkir, Delisma Marsauli
Jurnal Penelitian Farmasi Dan Herbal Vol 8 No 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2704

Abstract

This study aimed to formulate and evaluate the fragrance longevity of lily flower (Lilium longiflorum) spray perfume. Lily essential oil was extracted using steam distillation and formulated at concentrations of 5%, 10%, and 15% with additional fixatives, solvents, solubilizers, and preservatives. Evaluations included organoleptic tests, density, pH, fragrance longevity, stability, and aroma preference. Results showed that all formulations had good clarity, homogeneity, and skin-safe pH values (5.29–5.55). Formula 2 (10%) provided the best balanced fragrance intensity and received the highest preference score from panelists. The longest fragrance retention was achieved by Formula 3 (15%), though its intensity was considered too strong. In conclusion, lily essential oil spray perfume can be formulated stably with adequate fragrance longevity, showing potential as a competitive natural perfume product.
Strategi Pengajaran Bahasa Inggris untuk Meningkatkan Daya Saing Internasional Mahasiswa Farmasi Mutia, Maulidina; Bukit, Herawati Br
Jurnal Penelitian Farmasi Dan Herbal Vol 8 No 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2709

Abstract

Kemahiran berbahasa Inggris telah menjadi persyaratan krusial untuk meningkatkan daya saing global mahasiswa farmasi di era globalisasi dan Masyarakat 5.0. Penelitian ini bertujuan untuk mengidentifikasi dan membandingkan metode pengajaran bahasa Inggris yang efektif bagi mahasiswa farmasi untuk meningkatkan kompetensi internasional mereka. Metode penelitian yang digunakan adalah tinjauan pustaka dari berbagai jurnal yang diterbitkan dalam empat tahun terakhir. Temuan menunjukkan bahwa Bahasa Inggris untuk Tujuan Khusus (ESP), Pembelajaran Berbasis Tugas (TBL), dan Pembelajaran Campuran merupakan strategi yang paling efektif. ESP meningkatkan pemahaman terminologi farmasi, TBL meningkatkan keterampilan komunikasi dalam konteks klinis, dan Pembelajaran Campuran memberikan fleksibilitas dan akses pembelajaran yang lebih luas. Integrasi ketiga metode ini dianggap sebagai pendekatan yang paling relevan untuk meningkatkan kualitas pendidikan bahasa Inggris di institusi pendidikan tinggi terkait kesehatan.
FORMULASI DAN UJI AKTIVITAS SEDIAAN GEL ANTIACNE EKSTRAK ETANOL DAGING KURMA (Pheonix dactylifera L.) TERHADAP BAKTERI Propionibacterium acnes & Pseudomonas aeruginosa Marbun, Nova rianti; Br Sembiring, Tio Ranti Sari
Jurnal Penelitian Farmasi Dan Herbal Vol 8 No 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2710

Abstract

Acne (acne vulgaris) is a skin inflammation caused by the overgrowth of bacteria such as Propionibacterium acnes and Pseudomonas aeruginosa. This study aims to formulate a gel preparation containing ethanol extract of date flesh and evaluate its antibacterial activity. The extract was obtained via maceration using 70% ethanol. The gel was formulated in three extract concentrations: 10%, 20%, and 30%. Physical evaluations of the gel included organoleptic properties, homogeneity, pH, spreadability, and adhesiveness, while antibacterial activity was tested using the disk diffusion method. The results showed that the 30% concentration provided the largest inhibition zone against both test bacteria. Physical evaluations confirmed that the gel preparation met the criteria for a stable topical product. It can be concluded that the ethanol extract of date flesh can be effectively formulated into an antibacterial gel preparation and has potential as a natural antiacne product.
PENGARUH LAMA PENYIMPANAN PADA SUHU DINGIN TERHADAP KADAR VITAMIN C BUAH PIR (Pyrus communis) DENGAN METODE SPEKTROFOTOMETRI UV-Vis Br Bangun, Sofia Eliasari; Purba, Jhan Saberlan; Sulasmi, Sulasmi; Dhini, Fitri Wahyu; Ronaldy, Henri
Jurnal Penelitian Farmasi Dan Herbal Vol 8 No 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2731

Abstract

Vitamin C merxupakan vitamin yang penting xuntxuk txubxuh. Vitamin C mxudah larxut dalam air dan yang paling tidak stabil karena mxudah rxusak oleh panas dan penyimpanan. Vitamin C banyak terkandxung dalam berbagai sayxuran dan bxuah-bxuahan segar. Salah satxu bxuah yang mengandxung vitamin C adalah bxuah pir. Txujxuan dari penelitian ini adalah xuntxuk mengetahxui pengarxuh lama penyimpanan pada sxuhxu dingin terhadap kadar vitamin C bxuah pir. Penelitian ini menggxunakan metode ekperimental yaitxu xuntxuk menentxukan kadar vitamin C dalam sampel. Hasil dari penelitian ini yaitxu didapat kadar awal tertinggi pada pir centxury (1,611 mg/g). Namxun setelah 6 hari terjadi penxurxunan kadar secara signifikan 0,880 mg/g (±45%), pada pir xiangli hari 0 didapat kadarnya 1,362 mg/g, pada hari ke-6 penxurxunan kadar vitamin c menjadi 0,518 mg/g (±62%). Pada pir jambxu kadar vitamin C awal sebesar 0,814 mg/g. Setelah disimpan selama 6 hari menxurxun menjadi 0,330 mg/g (±59%). Berdasarkan hasil penelitian terjadi penxurxunan kadar vitamin C pada ketiga jenis bxuah pir secara signifikan dikarenakan vitamin C mxudah sekali teroksidasi, baik oleh temperatxur, cahaya maxupxun xudara sekitar sehingga kadar vitamin C tetap berkxurang walaxupxun disimpan dalam sxuhxu dingin. Kesimpxulannya, terjadi penxurxunan kadar vitamin C pada ketiga jenis bxuah pir secara signifikan dikarenakan vitamin C mxudah sekali teroksidasi, baik oleh temperatxur, cahaya maxupxun xudara sekitar walaxupxun disimpan pada sxuhxu dingin.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL BONGGOL BROKOLI (Brassica oleracea L. var. Italica) DENGAN METODE DPPH (1,1-Diphenyl-2-Picrylhydrazy) Umaya, Chindy; Marbun, Nova Rianti; Br Sembiring, Tio Ranti Sari
Jurnal Penelitian Farmasi Dan Herbal Vol 8 No 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2732

Abstract

Broccoli (Brassica oleracea L. var. Italica) is a vegetable recognized for its abundant bioactive components, such as flavonoids, tannins, saponins, and vitamin C, which are linked to antioxidant capabilities. Notwithstanding its health advantages, the broccoli stalk is frequently disregarded and underexploited, despite its potential as a source of natural antioxidant chemicals. This work aims to assess the antioxidant activity of the ethanolic extract from broccoli stalks utilizing the DPPH method and to ascertain its IC₅₀ value. The extraction was conducted via the maceration method utilizing 70% ethanol, and the antioxidant activity was assessed through UV-Vis spectrophotometry at a peak wavelength of 516 nm. The results indicated that the ethanolic extract of broccoli stem possesses considerable antioxidant activity, with an IC₅₀ value of 35.74 µg/ml. The IC₅₀ value of vitamin C was shown to be 7.67 µg/ml. The results indicate that broccoli stalks may be a significant source of natural antioxidants. The validation of the analytical method demonstrated outstanding results, including linearity (r = 0.9989), accuracy (100.57%), and precision (%RSD = 0.5646%).

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