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Jurnal Penelitian Farmasi dan Herbal
Published by INSTITUT KESEHATAN DELI HUSADA DELI TUA
ISSN : -     EISSN : 26547619     DOI : 10.36656/jpfh
Core Subject : Health,
Medicine & Pharmacology
Aims and Scope The Pharmaceutical & Herb Research Journal is a scientific journal published by Institut Kesehatan Deli Husada which publishes research journals in the field of pharmacy. Indonesia has a lot of natural resources that have the potential to have pharmacological effects. This journal is a place for researchers in the field of pharmacy to be able to publish their researches in 2 main areas, namely Pharmacy and Herbs In the Pharmacy area, accepted research articles include: • Pharmaceutical Biology • Pharmaceutical Chemistry • Pharmacology • Pharmaceutical Technology While the Herb area includes • Herb medicinal formulations from natural ingredients The Pharmaceutical & Herb Research Journal can also be a forum for informations and sources of knowledge related to the field of pharmaceutical science and herb medicine in Indonesia.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 233 Documents
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Strategi Pengajaran Bahasa Inggris untuk Meningkatkan Daya Saing Internasional Mahasiswa Farmasi Mutia, Maulidina; Bukit, Herawati Br
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2709

Abstract

Kemahiran berbahasa Inggris telah menjadi persyaratan krusial untuk meningkatkan daya saing global mahasiswa farmasi di era globalisasi dan Masyarakat 5.0. Penelitian ini bertujuan untuk mengidentifikasi dan membandingkan metode pengajaran bahasa Inggris yang efektif bagi mahasiswa farmasi untuk meningkatkan kompetensi internasional mereka. Metode penelitian yang digunakan adalah tinjauan pustaka dari berbagai jurnal yang diterbitkan dalam empat tahun terakhir. Temuan menunjukkan bahwa Bahasa Inggris untuk Tujuan Khusus (ESP), Pembelajaran Berbasis Tugas (TBL), dan Pembelajaran Campuran merupakan strategi yang paling efektif. ESP meningkatkan pemahaman terminologi farmasi, TBL meningkatkan keterampilan komunikasi dalam konteks klinis, dan Pembelajaran Campuran memberikan fleksibilitas dan akses pembelajaran yang lebih luas. Integrasi ketiga metode ini dianggap sebagai pendekatan yang paling relevan untuk meningkatkan kualitas pendidikan bahasa Inggris di institusi pendidikan tinggi terkait kesehatan.
FORMULASI DAN UJI AKTIVITAS SEDIAAN GEL ANTIACNE EKSTRAK ETANOL DAGING KURMA (Pheonix dactylifera L.) TERHADAP BAKTERI Propionibacterium acnes & Pseudomonas aeruginosa Marbun, Nova rianti; Br Sembiring, Tio Ranti Sari
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2710

Abstract

Acne (acne vulgaris) is a skin inflammation caused by the overgrowth of bacteria such as Propionibacterium acnes and Pseudomonas aeruginosa. This study aims to formulate a gel preparation containing ethanol extract of date flesh and evaluate its antibacterial activity. The extract was obtained via maceration using 70% ethanol. The gel was formulated in three extract concentrations: 10%, 20%, and 30%. Physical evaluations of the gel included organoleptic properties, homogeneity, pH, spreadability, and adhesiveness, while antibacterial activity was tested using the disk diffusion method. The results showed that the 30% concentration provided the largest inhibition zone against both test bacteria. Physical evaluations confirmed that the gel preparation met the criteria for a stable topical product. It can be concluded that the ethanol extract of date flesh can be effectively formulated into an antibacterial gel preparation and has potential as a natural antiacne product.
PENGARUH LAMA PENYIMPANAN PADA SUHU DINGIN TERHADAP KADAR VITAMIN C BUAH PIR (Pyrus communis) DENGAN METODE SPEKTROFOTOMETRI UV-Vis Br Bangun, Sofia Eliasari; Purba, Jhan Saberlan; Sulasmi, Sulasmi; Dhini, Fitri Wahyu; Ronaldy, Henri
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2731

Abstract

Vitamin C merxupakan vitamin yang penting xuntxuk txubxuh. Vitamin C mxudah larxut dalam air dan yang paling tidak stabil karena mxudah rxusak oleh panas dan penyimpanan. Vitamin C banyak terkandxung dalam berbagai sayxuran dan bxuah-bxuahan segar. Salah satxu bxuah yang mengandxung vitamin C adalah bxuah pir. Txujxuan dari penelitian ini adalah xuntxuk mengetahxui pengarxuh lama penyimpanan pada sxuhxu dingin terhadap kadar vitamin C bxuah pir. Penelitian ini menggxunakan metode ekperimental yaitxu xuntxuk menentxukan kadar vitamin C dalam sampel. Hasil dari penelitian ini yaitxu didapat kadar awal tertinggi pada pir centxury (1,611 mg/g). Namxun setelah 6 hari terjadi penxurxunan kadar secara signifikan 0,880 mg/g (±45%), pada pir xiangli hari 0 didapat kadarnya 1,362 mg/g, pada hari ke-6 penxurxunan kadar vitamin c menjadi 0,518 mg/g (±62%). Pada pir jambxu kadar vitamin C awal sebesar 0,814 mg/g. Setelah disimpan selama 6 hari menxurxun menjadi 0,330 mg/g (±59%). Berdasarkan hasil penelitian terjadi penxurxunan kadar vitamin C pada ketiga jenis bxuah pir secara signifikan dikarenakan vitamin C mxudah sekali teroksidasi, baik oleh temperatxur, cahaya maxupxun xudara sekitar sehingga kadar vitamin C tetap berkxurang walaxupxun disimpan dalam sxuhxu dingin. Kesimpxulannya, terjadi penxurxunan kadar vitamin C pada ketiga jenis bxuah pir secara signifikan dikarenakan vitamin C mxudah sekali teroksidasi, baik oleh temperatxur, cahaya maxupxun xudara sekitar walaxupxun disimpan pada sxuhxu dingin.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL BONGGOL BROKOLI (Brassica oleracea L. var. Italica) DENGAN METODE DPPH (1,1-Diphenyl-2-Picrylhydrazy) Umaya, Chindy; Marbun, Nova Rianti; Br Sembiring, Tio Ranti Sari
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2732

Abstract

Broccoli (Brassica oleracea L. var. Italica) is a vegetable recognized for its abundant bioactive components, such as flavonoids, tannins, saponins, and vitamin C, which are linked to antioxidant capabilities. Notwithstanding its health advantages, the broccoli stalk is frequently disregarded and underexploited, despite its potential as a source of natural antioxidant chemicals. This work aims to assess the antioxidant activity of the ethanolic extract from broccoli stalks utilizing the DPPH method and to ascertain its IC₅₀ value. The extraction was conducted via the maceration method utilizing 70% ethanol, and the antioxidant activity was assessed through UV-Vis spectrophotometry at a peak wavelength of 516 nm. The results indicated that the ethanolic extract of broccoli stem possesses considerable antioxidant activity, with an IC₅₀ value of 35.74 µg/ml. The IC₅₀ value of vitamin C was shown to be 7.67 µg/ml. The results indicate that broccoli stalks may be a significant source of natural antioxidants. The validation of the analytical method demonstrated outstanding results, including linearity (r = 0.9989), accuracy (100.57%), and precision (%RSD = 0.5646%).
UJI EFEKTIVITAS ANTIDIABETES EKSTRAK ETANOL DAUN PEPAYA (Carica papaya L.) TERHADAP PENURUNAN KADAR GLUKOSA DARAH TIKUS PUTIH (Rattus norvegicus) YANG DIINDUKSI ALOKSAN Gultom, Evi Deviana
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2733

Abstract

Penelitian ini bertujuan untuk mengetahui efektivitas ekstrak etanol daun pepaya (EEDP) terhadap penurunan kadar glukosa darah pada tikus putih jantan (Rattus norvegicus) yang diinduksi aloksan, menentukan dosis yang paling efektif, dan membandingkannya dengan glibenklamid. Penelitian ini menggunakan metode eksperimen dengan rancangan post-test only control group design. Sampel daun pepaya dikumpulkan secara purposive dari Kabupaten Batu Bara, diolah menjadi obat sederhana, dan diekstraksi menggunakan metode maserasi dengan etanol 96%. Skrining fitokimia menunjukkan bahwa EEDP mengandung flavonoid, alkaloid, saponin, tanin, dan steroid/triterpenoid. Hewan uji dibagi menjadi lima kelompok: kontrol negatif (CMC Na 0,5%), kontrol positif (glibenklamid 0,45 mg/kgBB), dan tiga kelompok perlakuan dosis EEDP 100, 200, dan 400 mg/kgBB. Induksi diabetes dilakukan dengan menggunakan aloksan monohidrat. Kadar glukosa darah diukur menggunakan glukometer sebelum dan sesudah perlakuan. Hasil penelitian menunjukkan bahwa pemberian EEDP pada ketiga dosis mampu menurunkan kadar glukosa darah secara signifikan dibandingkan dengan kontrol negatif. Dosis 400 mg/kgBB memberikan penurunan paling besar dan mendekati efektivitas glibenklamid. Uji statistik tidak menunjukkan perbedaan yang signifikan antara kelompok EEDP pada dosis 400 mg/kgBB dan glibenklamid (p>0,05), yang mengindikasikan bahwa efek antidiabetik EEDP sebanding dengan obat konvensional. Mekanisme penurunan glukosa darah diduga terkait dengan kemampuan flavonoid untuk meningkatkan sensitivitas insulin, melindungi sel β pankreas, dan menghambat enzim α-glukosidase. Sebagai kesimpulan, EEDP berpotensi sebagai agen antidiabetik alami, dengan dosis optimal 400 mg/kgBB, yang efektivitasnya sebanding dengan glibenklamid. Temuan ini mendukung penggunaan daun pepaya sebagai obat tradisional yang aman, terjangkau, dan mudah didapat, serta membuka peluang untuk penelitian lebih lanjut dalam pengembangan fitofarmaka antidiabetik.
“UJI EFEKTIVITAS FORMULASI EKSTRAK ETANOL BUAH PARE (Momordica charantia L.) DENGAN DAUN PEPAYA (Carica Papaya L.) SEBAGAI LOTION AEDES AEGYPTI” SEMBIRING, TIO RANTI SARI; Simorangkir, Delisma Marsauli
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2734

Abstract

Flaviviridae, genus Flavivirus, and group of arthropod-borne viruses. Aedes mosquitoes, particularly Aedes aegypti or Aedes albopictus, are the primary vectors of dengue disease transmission. A product that is used in skin-protection cosmetics to protect the skin from mosquito bites is anti-mosquito lotion (repellent). Water, emulsifying agents, humectants, and fatty ingredients make up lotion preparations. The bitter gourd and papaya leaves employed in this study were the active ingredients used to make lotion preparations. The lotion formulation used in this investigation contained flavonoid chemicals at varied extract concentrations of 0%, 2%, 4%, and 6%. The bitter gourd's and leaves' active components Because papaya is known to contain a lot of antioxidants, it can be used as an insecticide and lotion to ward against mosquitoes. According to SNI-16-4399-1996, preparations for anti-mosquito lotion made from papaya leaves and bitter melon extract pass the physical quality test because they are all homogeneous, have an oil-in-water emulsion type, are stable during storage for two weeks, and do not irritate the skin. Anti-mosquito lotion made with bitter melon fruit extract and papaya leaves, which is distinguished by the presence of dead mosquitoes in each formulation, has an effect on the effectiveness as an insecticide or repellent against mosquitoes on the skin that is applied. The extract lotion preparations' concentration The most powerful insecticide or mosquito repellant is a 6% extract of bitter gourd fruit and papaya leaves.
FORMULASI SEDIAAN LILIN EKSTRAK MINYAK ATSIRI BUNGA SEDAP MALAM (Polianthes tuberosa ) SEBAGAI AROMATERAPI anggara, Elysa; Harahap, Nina Irmayanti
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2737

Abstract

Stress is a common phenomenon that significantly impacts physical and mental health. One natural method widely developed to promote relaxation is aromatherapy. This study aimed to formulate tuberose (Polianthes tuberosa) essential oil into aromatherapy candles and evaluate their physical characteristics. Essential oil extraction was carried out using steam distillation, then formulated into candles using paraffin and stearic acid as the base ingredients. Four formulas with varying essential oil concentrations were selected: F1 (0 mL), F2 (5 mL), F3 (10 mL), and F4 (15 mL). Evaluation included organoleptic tests (color, aroma, and shape), homogeneity, melting point, and physical stability. The results showed that the candle with the addition of 15 mL of essential oil (F4) had the best physical characteristics: even color, a smooth surface, no cracks, easy lighting, and a strong, distinctive, calming aroma. Based on the evaluation results, tuberose essential oil was successfully formulated into a stable aromatherapy candle with the potential to provide a relaxing effect.
STUDI PENGGUNAAN ANTIHIPERTENSI ORAL PADA PASIEN HIPERTENSI RAWAT JALAN DI PUSKESMAS NGESREP PERIODE 2025 Silvianasari, Firly Nur
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 2 (2026): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

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Abstract

Hypertension is a chronic disease with a high prevalence and a significant contribution to morbidity and mortality in Indonesia. The appropriate use of antihypertensive drugs plays a crucial role in achieving optimal blood pressure control. This study aims to describe the pattern of oral antihypertensive use and evaluate its effectiveness based on changes in blood pressure before and after treatment among outpatient hypertension patients at Ngesrep Primary Health Center during the period of January–April 2025. This research employed an observational design with a retrospective descriptive approach through the review of medical records of hypertensive patients who met the inclusion criteria. A total of 30 medical records were obtained using purposive sampling. Data were analyzed using the Kolmogorov-Smirnov normality test followed by the Paired T-Test to assess differences in systolic and diastolic blood pressure before and after therapy. The results showed that amlodipine, particularly the 10 mg dosage, was the most frequently used antihypertensive. Statistical analysis demonstrated a significant reduction in both systolic and diastolic blood pressure after treatment (p < 0.05), indicating that the antihypertensive regimen administered was effective. In conclusion, oral antihypertensive therapy in this setting showed a positive effect in lowering blood pressure among outpatient hypertension patients
This AUREY BOMB (INOVASI SABUN MANDI KOMBINASI Hylocereus polyrhizus dan Lavandula angustifolia SEBAGAI ANTIOKSIDAN dan MERELAXKAN TUBUH) ., Syarifah Roihanah; Putri, Nesya Cantika; Falabiba, Askya; Prehandhini, Meytha Putri
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 2 (2026): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study aims to develop a bath bomb formulation based on red dragon fruit peel (Hylocereus polyrhizus) as an innovation in natural, eco-friendly body care products. Dragon fruit peel was chosen because it contains bioactive compounds such as vitamin C, flavonoids, and betalains, which have potential as antioxidants and natural colorants. This research used an experimental method with variations in extract concentration and evaluation of the physical characteristics of the product, including organoleptic test, pH, effervescent time, foam height, and specific gravity. The results showed that bath bombs containing dragon fruit peel extract had good physical characteristics: solid, stable, easily soluble (<5 minutes), and pH within a safe range (6–7.5). Additionally, variations in fragrance concentration affected aroma acceptance, with moderate concentrations producing the most balanced and preferred scent. These findings indicate that dragon fruit peel can be utilized as a natural active ingredient in bath bomb formulations to create value-added, sustainable, and eco-friendly body care products.
GAMBARAN PELAYANAN INFORMASI OBAT (PIO) DI PUSKESMAS UJOH BILANG KABUPATEN MAHAKAM ULU BERDASARKAN PERMENKES RI NO. 74 TAHUN 2016 Saputro, Joko Suryo; wijaya, heri; Helmidanora, Rusdiati
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 2 (2026): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

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Abstract

Penelitian ini bertujuan untuk menggambarkan pelaksanaan Pelayanan Informasi Obat (PIO) di Puskesmas Ujoh Bilang Kabupaten Mahakam Ulu berdasarkan Peraturan Menteri Kesehatan Republik Indonesia Nomor 74 Tahun 2016. Penelitian ini merupakan penelitian observasional deskriptif dengan rancangan cross sectional. Data dikumpulkan secara prospektif menggunakan lembar checklist dan wawancara terhadap apoteker dan tenaga kefarmasian yang memberikan pelayanan informasi obat kepada pasien. Aspek yang diamati meliputi ketersediaan informasi obat, penyampaian informasi oleh tenaga farmasi, pemahaman pasien, pemantauan penggunaan obat, serta sarana dan prasarana pendukung PIO. Hasil penelitian menunjukkan bahwa sebagian besar komponen Pelayanan Informasi Obat telah dilaksanakan dengan baik, terutama pada aspek penyampaian informasi dan pemahaman pasien. Namun demikian, masih ditemukan keterbatasan pada aspek sarana prasarana, khususnya ketersediaan ruang konsultasi khusus. Kesimpulan penelitian ini menunjukkan bahwa pelaksanaan PIO di Puskesmas Ujoh Bilang secara umum telah sesuai dengan ketentuan Permenkes RI Nomor 74 Tahun 2016, namun masih memerlukan peningkatan pada beberapa aspek pendukung untuk optimalisasi pelayanan kefarmasian.

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