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Jurnal Farmasi dan Sains Indonesia (JFSI)
Published by Sekolah Tinggi Ilmu Farmasi Nusaputera
ISSN : 26219360     EISSN : 26863529     DOI : https://doi.org/10.52216
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Medicine & Pharmacology Neuroscience
Focus and Scope Jurnal Farmasi & Sains Indonesia is an open-access journal that published twice a year by Sekolah Tinggi Ilmu Farmasi Nusaputera. This journal is a media of research publication on all aspects of pharmaceutical & science that is innovative, creative, original and based on scientific. Articles published in this journal about drug discovery, drug delivery systems and drug development with specific field include: 1. Medicinal chemistry 2. Pharmacology 3. Pharmacokinetics 4. Pharmacodynamics 5. Pharmaceutical analysis 6. Drug delivery systems 7. Pharmaceutical technology 8. Pharmaceutical biotechnology 9. Herbal medicines and active components 10. Clinical evaluation of the medicine
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 32 Documents
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Search results for , issue "Vol 8 No 1 (2025)" : 32 Documents clear
TINGKAT KEPATUHAN MINUM OBAT PADA PASIEN RAWAT JALAN SKIZOFRENIA DI WILAYAH KERJA PUSKESMAS X KABUPATEN TASIKMALYA Sidik, Hasbi Muhammad; Alifiar, Ilham; Salasanti, Citra Dewi
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p140-144

Abstract

Schizophrenia is a chronic mental condition characterized by communication disturbances, impaired reality perception, abnormal emotional behavior, and cognitive function impairment. According to the WHO in 2022, there are approximately 24 million people with schizophrenia worldwide, with the highest prevalence in East Asia (8 million), followed by South Asia (4 million) and Southeast Asia (2 million). In Indonesia, the 2018 Riskesdas survey reported a prevalence of 6.7% for schizophrenia per 1000 households. This study aims to determine the extent of medication adherence among outpatient schizophrenia patients in the working area of Health Center X in Tasikmalaya Regency. The observational method with a cross-sectional approach was used, where data were prospectively collected through interviews using the Medication Adherence Rating Scale (MARS) questionnaire. The study subjects consisted of 13 respondents who were schizophrenia patients receiving treatment at Health Center X in Tasikmalaya Regency. The research findings indicate that 9 out of 13 respondents had high adherence levels, while the remaining 4 had low adherence levels. Factors such as gender, age, education level, occupation, and marital status did not significantly influence medication adherence.
Pemanfaatan Minyak Atsiri Kulit Jeruk Bali (Citrus maxima) Sebagai Alternatif Antibakteri Staphylococcus epidermidis dan Staphylococcus aureus Pada Deodoran spray Octaviani, Dilha; Farid, Nurfiddin; Syarifuddin, Surya
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p1-6

Abstract

Cleanliness and body odor are major and important factors of personal hygiene and appearance. If a person's body smells good, their self-confidence will be higher. Using soap and water as a body wash when bathing is relatively ineffective in preventing body odor. So several other alternative actions can be taken, such as using anti-body odor cosmetic preparations (deodorant). This research aims to determine whether grapefruit peel (Citrus maxima) essential oil can be formulated as a spray deodorant that meets physical quality requirements and to determine its antibacterial effectiveness on Staphylococcus epidermidis and Staphylococcus aureus. The method used in this research is experimental with a formula design divided into four formulas, F0 without essential oil, F1 with the addition of 0.5% essential oil, F2 with the addition of 1% essential oil, and F3 with the addition of 1.5% essential oil. The finished doedorant preparation was then subjected to organoleptic testing, homogeneity, pH, dry time, spraying pattern, cycling test for 6 cycles, and antibacterial activity test. The results of this research show that grapefruit peel (Citrus maxima) essential oil can be made into a spray deodorant that meets physical quality requirements. The results of the research show that the formulation has antibacterial activity against Staphylococcus aureus bacteria, with an F1 inhibition zone of 0.5% 3.8 mm (weak), F2 1% 4.5 mm (weak), F3 1.5% 15.2mm (strong). In Staphylococcus epidermidis bacteria, the inhibition zone is F1 0.5% 3.5 mm (weak), F2 1% 4.6 mm (weak), and F3 1.5% 14.8 mm (strong).
Kajian Penggunaan Obat Nasofaringitis Akut Berdasarkan Indikator Peresepan World Health Organization (WHO) di Puskesmas Antibar Mempawah Putri, Nabilah Ananda; Susanti, Ressi; Kusharyanti, Indri
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p7-14

Abstract

Acute nasopharyngitis is a mild respiratory infection caused by a virus. This disease is common in children to adults. The World Health Organization (WHO) states that more than 50% of drugs are used inappropriately, causing polypharmacy, antibiotic resistance, wasteful costs and drug interactions. This study aims to assess the appropriateness of drug use for acute nasopharyngitis at Antibar Mempawah Community Health Center based on WHO prescribing indicators. This study is a non-experimental study with a descriptive cross sectional design. Data were collected retrospectively through 411 medical records of acute nasopharyngitis patients in 2022 with randomized sampling technique. The results obtained were the average number of drug items per prescription sheet was 3.35, the percentage of drugs prescribed with generic names was 95.13%, prescribing drugs with antibiotics was 42%, prescribing drugs with injection preparations was 0%, drugs prescribed based on the National Formulary was 75.9%.
Pengaruh Label Halal Pada Kemasan Obat Herbal Terhadap Keputusan Pembelian Di Apotek Cangkiran Arfianto, Erki; Marceilha, Nadya; Ningtyas, Ery Ardiyanti
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p251-256

Abstract

Considering that the majority of Indonesia's population is Muslim, pharmaceutical products must have halal certification and labeling. Consuming something halal is a mandatory thing for Muslims. Use of herbal medicine When consuming a herbal medicine product, one must pay attention to the halal status of the medicine by seeing whether there is a halal logo on the herbal medicine. The purpose of this study was to determine whether the halal label of herbal medicine influences consumer purchasing decisions at the Cangkiran Pharmacy and to determine the level of public knowledge of the halal label. This type of research uses a quantitative descriptive approach with a sampling technique method using purposive sampling. The instrument used is a questionnaire with validation and reliability tests. The results of the study showed that the results of the validation test were declared valid and the reliability test was declared reliable or trustworthy. for questionnaire questions showed the highest average percentage, namely agree (ST). This can indicate that the decision to buy halal-labeled herbal medicine is largely influenced by the halal label.
FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN ACNE PATCH EKSTRAK ETANOL DAUN CENGKIH (Syzygium aromaticum) TERHADAP BAKTERI Propionibacterium acnes Nurfadilah, Ratna; Rizkuloh, Lina Rahmawati; Nofriyaldi, Ali
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p145-155

Abstract

There are many major problems with the skin, especially the face, that occur in some men and women. Acne is a skin disorder characterized by inflammation of the skin. Acne caused by Propionibacterium acnes bacteria is generally treated by Clindamycin capsules 300 g. However, the drug clyndamicin used by the oral route has side effects. So, there are alternative anti-acne drugs that have fewer side effects. Clove leaves from the clove tree can be used as medicine. The tannin compounds in clove leaves have antibacterial activity. In this research method, an acne patch preparation is made from clove leaf extract (includes collecting the ingredients to be tested, namely clove leaves, processing simplicia, making extracts, making acne patch formulations, and testing the antibacterial activity of Propionibacterium acnes using the well method. The results of the highest inhibition large, namely at F3 (10%) at 21,213mm very strong, F2 (7.5%) at 19,658mm strong and F1 (5%) at 18,788mm strong.  
Review Artikel: Tumbuhan Dari Arboretum Garut Yang Berpotensi Sebagai Hepatoprotektor Qowiyyah, Atun; Fadhilla, Genialita; Ritonga, Hermida
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p69-80

Abstract

Hati berperan penting dalam proses metabolisme, konjugasi dan detoksifikasi, oleh karena itu mengonsumsi berbagai zat toksik dapat menyebabkan kerusakan hati. Penting untuk mencegah paparan zat toksik atau menggunakan zat yang dapat melindungi hati, yaitu hepatoprotektor yang dapat diperoleh dari bahan-bahan herbal, salah satunya berasal dari Arboretum Garut. Koleksi tanaman Arboretum Garut telah diinventarisasi tetapi efek hepatoprotektor dari tanaman tersebut belum diidentifikasi. Ulasan artikel ini bertujuan untuk mencari informasi ilmiah tentang beberapa tanaman di Arboretum Garut yang berpotensi memiliki aktivitas hepatoprotektif. Metode yang digunakan adalah studi literatur, tahap pertama literatur offline, kemudian studi literatur online berupa artikel ilmiah yang dipublikasikan secara online di jurnal nasional dan internasional yang terakreditasi dan diterbitkan dalam 10 tahun terakhir. Berdasarkan hasil kajian, terdapat 25 tanaman dari 20 famili yang berpotensi memiliki aktivitas hepatoprotektif yang telah diuji secara in vivo ditandai dengan adanya penurunan aktivitas enzim ALT, AST, ALP, kadar bilirubin, dan MDA, peningkatan kadar albumin, dan protein total, serta perbaikan histopologi hati. Tanaman pangan tersebut adalah: Anacardiaceae (mangga dan jambu mete), Mimosaceae (petai dan trembesi), Lauraceae (alpukat dan kayu manis), Moraceae (nangka dan sukun), Musaceae (pisang), Annonaceae (suku), Apocynaceae (pule), Clusiaceae (manggis), Ebenaceae (kesemek), Elaocarpaceae (kersen), Euphorbiaceae (ubi kayu), Lamiaceae (jati), Magnoliaceae (camilan kuning), Malvaceae (gedi), Oxalidaceae (belimbing), Punicaceae (delima), Rutaceae (jeruk nipis), Sapindaceae (matoa), Sapotaceae (sapodilla manila).
UJI AKTIVITAS ANTIBAKTERI SEDIAAN MASKER CLAY DARI EKSTRAK DAUN KELOR ( Moringa Oliefera L. ) SEBAGAI SEDIAAN ANTI JERAWAT TERHADAP BAKTERI Staphylococcus Aureus ATCC 25923 Rahmasari, Khusna Santika; Waznah, Urmatul; Slamet, Slamet; Mafruroh, Mafruroh
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p234-242

Abstract

Acne can disrupt appearance and cause discomfort due to pain. The bacteria that can cause acne is Staphylococcus aureus. Excessive or inappropriate use of antibiotics can lead to antibiotic resistance. One plant that has effectiveness as an antibacterial is Moringa leaves (Moringa Oliefera L.). The application of Moringa leaf extract as an antibacterial can be made into a clay mask preparation. The purpose of this study was to prove that Moringa leaf extract can be used as a clay mask and a clay mask preparation of Moringa leaf extract as an anti-acne against Staphylococcus aureus bacteria. Moringa leaf extract was obtained by maceration method with 96% ethanol solvent. The extract was formulated in the form of a clay mask with various concentrations of 15%, 20%, 25%. The results of the parameter tests included organoleptic, pH, homogeneity, spreadability, adhesiveness, viscosity and stability. Antibacterial activity tests were also carried out using the disc method. The research test of the inhibitory activity of the Moringa leaf extract clay mask showed good formula results at a concentration of 25% with an inhibitory diameter of 28.96 ± 0.43 mm. This study can be concluded that Moringa leaf extract can be formulated into a clay mask preparation and the resulting inhibition zone area with the clear zone area in Staphylococcus aureus bacteria.
EFEKTIVITAS EKSTRAK DAUN SALAM (Syzygium polyanthum) SEBAGAI ANTIDIARE PADA MENCIT BALB/C (Mus musculus) Khafidloh, Muizzatul; Sulistiawati, Erni; Sagatana, Ervina Nanda
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p243-250

Abstract

Bay leaves as a cooking ingredient in Indonesia are also a herbal medicinal plant as a traditional treatment for digestive problems such as diarrhea. This research aims to obtain information on the effective dosage of bay leaf extract (Syzygium polyanthum) as an antidiarrhea. This research used 15 mice and divided them into 5 groups which were carried out using two methods, namely intestinal protection and intestinal transit. The requirements are divided into negative control (1% CMC-Na suspension), positive control (Loperamide HCl 0.26 mg/KgBW), and groups with graded doses (50 mg/KgBW, 100 mg/KgBW, and 150 mg/KgBW) given sequential orally. The parameters observed in this study were defecation frequency, stool consistency, and the ratio of marker passages in the intestines of mice. A dose of 150 mg/KgBW provides the best antidiarrheal effect. This is proven by the significantly different results in the two methods that have been carried out for the drug loperamide. The content of tannins, flavonoids, and alkaloids in bay leaves provides an antidiarrheal effect on diarrheal diseases.
PEMBUATAN SABUN KERTAS EKSTRAK BUNGA TELANG DENGAN VARIASI SUHU DAN PENGADUKAN Novitasari, Aprilia Donna; Puspitasari, Dewi Fitriani; Ariani, Lilies Wahyu
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p15-20

Abstract

Soap is a health supply that is much needed to maintain cleanliness. Telang flowers have the potential to inhibit Staphylococcus aureus bacteria, so that their potential can be utilised in making soap made from nature. One form of soap that is currently trending is paper soap. Formulating bayang flower extract in paper soap making, it is necessary to pay attention to pH and temperature factors, because the colour stability of bayang flower anthocyanins is easily affected by temperature and pH. In paper soap making, temperature and stirring factors will also have an influence on the character of the resulting paper soap. In this study, a study was conducted to make bayang flower paper soap by looking at the effect of temperature during manufacture and stirring on the characteristics of soap including pH, moisture content, and colour of paper soap. The method of making paper soap is conditioned on variations in manufacturing temperature, namely 77 ° C, 85 ° C and 92 ° C and variations in stirring speed at 280, 350 and 420 rpm. The telang flower extract was made using the maceration method in a ratio of 1:6, using a combination of 70% ethanol and 0.42% NaOH solvents (6:4), the extract was used with a concentration of 10%. The results show that paper soap made with increasing temperature and stirring has a decreasing pH value and moisture content and has a darker green colour variation. Keywords: bay flower, paper soap, temperature
MONITORING SIDE EFFECTS OF ANTITUBERCULOSIS DRUGS (OATS) IN PATIENTS WITH TUBERCULOSIS AT TUGUREJO REGIONAL GENERAL HOSPITAL SEMARANG Yuliasari, Niken; Gloria, Fransisca; Dahliyanti, Novita Dwi; Ovikariani, Ovikariani; Sa’adah, Anifatus; Suwarni, Sri
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p21-25

Abstract

Monitoring of side effects of antituberculosis drugs (OAT) in tuberculosis (TB) patients during the intensive treatment phase. Tuberculosis, caused by Mycobacterium tuberculosis, requires the use of OAT which can cause a variety of side effects. Research shows that common side effects experienced by TB patients include joint pain, nausea, lack of appetite, and dizziness. The high incidence of these side effects has the potential to affect patient compliance in undergoing treatment, which has an impact on the success of TB therapy. The research method used is descriptive observation with a cross-sectional approach. Data was taken from patients undergoing treatment at various hospitals and health centers. The results showed that most patients experienced mild side effects, with frequency varying depending on the week of treatment. In the first week, almost all patients reported side effects, while the frequency tended to decrease over time. Regular monitoring of OAT side effects is essential to improve patient compliance and prevent treatment discontinuation. Health workers are expected to conduct periodic evaluations and provide support to patients to stay motivated. With effective monitoring, the risk of serious side effects can be minimized, and treatment outcomes for TB patients can be improved.

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