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Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 2502647X     EISSN : 25031902     DOI : https://doi.org/10.36387/jiis
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 429 Documents
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PENGETAHUAN, KUALITAS HIDUP DAN BIAYA SAKIT PASIEN DENGUE DI RS PKU MUHAMMADIYAH GAMPING Supadmi, Woro; Elvinda, Esty; Aryani Perwitasari, Dyah; Noor Faridah, Imaniar
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1428

Abstract

The incidence of dengue virus infection in the D.I. Yogyakarta reached 3,618 cases in 2020. Based on its clinical manifestations, dengue virus infection is divided into Dengue Fever (DF), Dengue Haemorrhagic Fever (DHF), and Dengue Shock Syndrome (DSS). This study aims to identify the level of knowledge, quality of life, and costs of dengue patients at PKU Muhammadiyah Gamping Hospital from March 2021 to October 2021. This study used a cross-sectional design. The measurement of the patient's knowledge level used a questionnaire knowledge of dengue, while the quality of life was assessed using EQ-5D-5L for adult patients and EQ-5D-Y for pediatric patients. The cost of illness data from the hospital finance database. This study involved 31 respondents with the characteristics aged 16-40 years (54.84%), male (87.1%), using BPJS insurance (80.65%), and an average length of stay of 4 days (51.61%). The patient's level of knowledge about dengue, knowledge of dengue prevention, and dengue prevention behavior reached 74.20% (sufficient), 74.20% (sufficient), and 77.42% (sufficient) respectively. The quality of life of dengue patients reached 100% and 85.2% in DF patients, while the DHF patients felt a few anxious/depressed (sad). The average cost of illness in DF patients was Rp. 2,796,386 and Rp. 3,378,537 in DHF patients.
PENGARUH KONSENTRASI ASAM HIALURONAT TERHADAP STABILITAS FISIK SALEP KOMBINASI EKSTRAK IKAN GABUS Lelek Kipli; Mohamad Andrie; Wintari Taurina
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1452

Abstract

The combination of snakehead fish ointment is expected to have synergistic properties in wound healing. Variations in natural ingredients added to the formula will affect the stability of the preparation during its shelf life. Hyaluronic acid, as a humectant agent, is used to maintain stability and improve physical properties by increasing the consistency of the preparation and reducing the risk of syneresis. The test method in this study was the stability test of the intermediate at 30°C ± 2°C/ RH 65 ± 5 % for six months. The Parameters measured were spreadability, adhesion, and pH. The observations showed that all formulas met the physical characteristics of the ointment until the 1st month. The 0.25% hyaluronic acid concentration was the most stable formula, which maintained the stability of spreadability and adhesion up to the 1st-month test point.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN JELANTIR (Conyza sumatrensis (Retz.) E. Walker) DALAM SEDIAAN DEODORAN SPRAY TERHADAP BAKTERI Staphylococcus epidermidis Agis Destriawan; Reni Mulyani; Salih Muharam
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1458

Abstract

The bacteria Staphylococcus epidermidis is known to cause body odour in the human body. A common method to kill bacteria that cause body odour is deodorant. Commercial deodorants contain aluminium chlorohydrate and the compound is known to increase the risk of skin cancer and alzheimer's disease. A candidate for a safer deodorant is one made from natural ingredients. One of the natural ingredients that has potential as a deodorant is jelantir leaves. The purpose of this study was to extract and characterise phytochemical compounds and test their antibacterial activity in deodorant spray preparations on Staphylococcus epidermidis. The extraction method used was maceration using ethanol solvent, extract characterisation using UV-Vis spectrophotometry and antibacterial test of deodorant spray preparation of jelantir leaf extract using disc diffusion. The results showed that jelantir leaf extract contained flavonoids 5.5727 ±0.1336 (%w/w QE), saponins 8.6472 ±0.0353 (% w/w SE), tannins 2.1448 ±0.0506 (%w/w TAE), steroids 1.0231 ±0.0083 (%w/w BSE), triterpenoids 0.9090 ±0.0030 (%w/w UAE) and the antibacterial test results had the highest inhibition zone diameter of 13.50 ±0.50 (mm) in formula 30 (%w/v).
STUDI ETNOMEDISIN PADA MASYARAKAT DI KAMPUNG DEMI, KABUPATEN BANTUL, YOGYAKARTA Fitra Romadhonsyah; Putrilia Dyah Puspitasari; Shubhi Mahmashony Harimurti; Arde Toga Nugraha
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1479

Abstract

Indonesian people are known to have traditional medicine using medicinal plants based on heritage or stories passed down from ancestors and are immaterial or mythical. The lack of documentation makes the use of traditional medicine not maximized. This study aims to determine the knowledge of the community regarding the use of medicinal plants as a treatment and to determine the types of plants used for treatment in Kampung Demi, Bantul, Yogyakarta. The sampling technique used was purposive sampling with observation using a questionnaire instrument. The number of respondents who met the inclusion criteria was 51 respondents. The result data was analyzed using ICF (Informant Consensus Factor). The results showed 97.12% of respondents understood the benefits of medicinal plants, 64.70% of respondents stated that understanding traditional medicine was hereditary from the family, 49.02% of respondents got medicinal plants from their own yard, 74.51% of respondents often used traditional medicine compared to conventional medicine, and there were 11 types of medicinal plants used by respondents for treatment. The categories of diseases treated with the most types of medicinal plants were ten types of medical diseases (ICF = 1.0) and two types of magical/non-medical habits (ICF = 1.0).
UJI EFEK ANALGETIK EKSTRAK ETANOL 96% DAUN KELAPA SAWIT (Elaeis guineensis Jacq) TERHADAP MENCIT (Mus Musculus) YANG DI INDUKSI ASAM ASETAT Rakhil Zulfansyah; Nur Mahdi; Raisha Hamiddani S
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1485

Abstract

In Indonesia, especially in Kalimantan, many oil palm plants (Elaeis guineensis Jacq) are found. The potential of this plant has not been fully exploited. A number of tests have been carried out, namely as an antioxidant, burn wound, larvicide and antibacterial. This research was conducted to identify the analgesic effectiveness of oil palm leaf extract (Elaeis guineensis Jacq) on white mice (mus musculus) given acetic acid. The extraction method used is meseration. The analgesic test uses a chemical stimulation method. 25 mice were divided into 5 groups (negative group Na CMC 0.5%, positive group Paracetamol, dose I 100 mg/kgBW, dose II 300 mg/kgBW, dose III 500 mg/kgBW). Each group was treated orally, after 30 minutes they were given 1% acetic acid intraperitoneally, then the total number of wriths, percent protection and one way ANOVA test were calculated. The experimental results showed that the positive control percent protection was 57.44%, dose I was 34.78%, dose II was 52.10%, and dose III was 70.87%. The results of the one way ANOVA test analysis showed significant differences between each treatment group except for dose II 300 mg/kgBB. It can be concluded that the ethanol extract of oil palm leaves (Elaeis guineensis Jacq) has effectiveness as an analgesic and at dose II 300 mg/kgBW is the most effective dose because it is close to the percent protection of the positive control (Paracetamol).
STUDI EFEKTIVITAS DAN EFEK SAMPING FAVIPIRAVIR PADA PASIEN COVID-19 PNEUMONIA DI RUMAH SAKIT BHAYANGKARA SURABAYA Rika Yulia; Fauna Herawati; Klara Rosjuita Hima; Ruddy Hartono; Puri Safitri Hanum
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1486

Abstract

Favipiravir's indication extended for COVID-19 disease. This background consideration is related to its mechanism of action or effectivity in some COVID-19 patients, with or without pneumonia. This research is a retrospective observational study and analysis descriptively. The research material is medical records of patients with COVID-19 pneumonia using favipiravir from December 2020-May 2021. A total of 33 samples obtained met the inclusion and exclusion criteria. Effectiveness was analyzed by calculating the percentage of COVID-19 pneumonia patients who only used favipiravir while they were being treated until the patient was discharged. The side effects were the number of COVID-19 patients who drug injury liver disease (AST and ALT increase more than three times upper limit) and neutrophenia. This study reported that favipiravir was effective in COVID-19 patients with pneumonia, seen from 78.79% of patients who only used favipiravir during treatment. There were no patients who had an increase in AST ALT >3×upper limit of normal, and only seven patients with neutropenia.
PERAN APOTEKER DALAM PEREDARAN OBAT SECARA DARING DI PRAKTIK KEFARMASIAN DI PURWOREJO Aminudin; Merari Peranginangin, Jason; Herdwiani, Wiwin
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1494

Abstract

Online drug distribution are one of the essential elements to realize health in health administration. The Food and Drug Monitoring Agency (BPOM) has provided and disseminated Regulation 8 of 2020 concerning the Control of Drugs and Food Circulated Online. This study aims to determine the role of pharmacists in online drug distribution in pharmaceutical practice. Sampling was done by purposive sampling with interviews. Informants in this study include pharmacists who practice in pharmacies that already serve online drug sales, furthermore, the data is processed with NVIVO 12 Pro software. The study results show that pharmacists' role in online drug distribution is to serve incoming drug requests, ensure the availability of quality drugs, ensure that these requests comply with applicable regulations, and ensure that the drugs reach patients safely
FORMULASI FILM FORMING SPRAY DARI KLORAMFENIKOL UNTUK LUKA Rusdiati Helmidanora; Siti Jubaidah; Is alukal Fauziah A.A
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1517

Abstract

The wound healing process should be short so as not to interfere with productivity and reduce costs. SFFS (spray film forming system) is a combination of transdermal preparations in which a polymer solution is sprayed onto the skin and will form an almost transparent film by evaporation of the solvent. Film-forming solutions are particularly advantageous for transporting the active substance to the site of action by the shortest route in cases of dermal or lower tissue infections. Chloramphenicol is a lipophilic drug so it penetrates the skin well because the stratum corneum matrix is ​​also lipophilic. The purpose of this study was to make a formulation of a sprayed chloramphenicol film-forming solution in order to obtain the best formula and increase effectiveness. The research was carried out on an experimental basis and three formulas were prepared with different polymer concentrations. The results of the study obtained a film-forming spray for each formula with a film formed that was flexible and adhered well to the skin, with a pH of 6. The time needed to make the film layer in skin is 0.87-1.19 minutes with an average dose weight of spray is 61.33-85.33 mg.
POTENSI KOMPOSIT OKSIDA LOGAM-KITOSAN SEBAGAI AGEN ANTIDIARE Siska Musiam; Eka Kumalasari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1535

Abstract

Diarrhea is a defecation disorder characterized by defecating more than three times a day with a liquid stool consistencBABy, which may be accompanied by blood and/or mucus. Infection is still the main cause of diarrhea. The large number of cases of diarrhea due to infection means that antibiotics are still widely used in treating diarrhea. Irrational use of antibiotics can result in the emergence of side effects and resistance. To prevent this, diarrhea treatment can use materials that are able to absorb toxins and bacteria in the digestive tract, and are safe for the human body. Chitosan is an environmentally friendly material that has a large network of pores. Some metal oxides have been found to have good chemical affinity. The metal oxide-chitosan composite in nano size is predicted to allow the absorption of toxins and bacteria, but is easily released again by the body. In this research, metal oxide (Fe)-chitosan composite material was synthesized using 2 methods designed to have an antidiarrheal effect. The antidiarrheal effect is observed by its ability to absorb liquids containing natural ingredients. The results of this research showed that the composite material synthesized using a liquid reaction (13,861 ppm to 11,082 ppm) produced a stronger adsorption capacity compared to the composite material synthesized using a solid reaction (13,861 ppm to 11,265 ppm).
FORMULASI DAN EVALUSI MUTU FISIK SABUN BATH BOMB EKSTRAK DAUN DADANGKAK (Hydrolea spinosa L.) Rakhmadhan Niah; Novia Ariani; Erna Prihandiwati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1608

Abstract

Dadangkak contains secondary metabolite compounds including Alkaloids, Steroids and Flavonoids. One of the compounds, namely flavonoids, has activity that can inhibit bacterial growth. The purpose of the study was to determine the effect of dadangkak leaf extract on bath bomb soap preparations and to determine the physical quality of bath boom soap dadangkak leaf extract. This research is a non-experimental research conducted at the STIKES ISFI Banjarmasin.  The study sample was dadangkak leaf extract. The research bath boom soap formulation then an evaluation of physical properties consisting of organoleptis test, soluble time, foam height, pH, specific gravity and alkali-free test. The data obtained is compared with SNI. The results of the physical properties test in formula 2 meets the requirements of physical properties with the following results pH 10; Free alkali test 0.06%; Specific gravity test 1.03g/mol; Froth height test 66 mm; Viscosity test 960 mPas. The conclusion of the study found that the formula that meets the requirements for the best physical properties of soap is formula 2 according to the s SNI 06-4085-1996.

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