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Bohari
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INDONESIA
Journal of Health and Nutrition Research
ISSN : -     EISSN : 28299760     DOI : https://doi.org/10.56303/jhnresearch
Core Subject : Health,
The Journal of Health and Nutrition Research (ISSN: 2829-9760) is an international peer-reviewed, scientific, and open-access journal managed by Media Publikasi Cendekia Indonesia. Journal of Health and Nutrition Research aims to provide forum exchanges and interfaces between researchers and related practitioners in the field of medicine, health, and nutrition. The journal only accepts articles from original research, review articles, and case study articles. Journal of Health and Nutrition Research is a scientific journal and focuses on medicine, health, and nutrition including: Medical and clinical research, Public health research Nursing research Food and nutrition research, Midwifery research Pharmacy research
Articles 308 Documents
Early Breastfeeding Practices, Energy and Protein Intake, Risk of Stunting in Coastal Areas of Sampang Regency, East Java Province: A Cross-Sectional Study Khomisah, Nuril Alfiatul; Hikmayani, Nur Hafidha; Probandari, Ari Natalia
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.550

Abstract

Stunting remains a significant public health issue in Indonesia, particularly in coastal areas with limited access to nutrition and healthcare services. This study aims to identify early risk factors for stunting in children aged 12–59 months in the coastal areas of Sampang Regency, East Java. The study design employed a cross-sectional approach with a sample size of 250 children, selected randomly in proportion to the population. Data were collected through anthropometric measurements, structured questionnaires, and 24-hour food recalls. Analysis was performed using the chi-square test and simple logistic regression. The results showed a prevalence of stunting of 25,2%. Not getting breast milk in the first two days postpartum (OR=2,447), not getting exclusive breastfeeding for <6 months (OR=2,766), insufficient energy intake (OR=27,695), and insufficient protein intake, which showed the highest risk (OR=192,85), were associated with stunting (p<0,05). In contrast, early initiation of breastfeeding and continued breastfeeding at 12–23 months of age were not significantly associated with stunting. These findings underscore the importance of early nutritional practices and adequate intake of macronutrients, particularly protein, in efforts to prevent stunting. Focused nutritional interventions during the first 1,000 days of life need to be prioritized, including improving maternal education and the quality of children’s food intake.
Nutritional, Physical Activity, and Mental Health Interventions to Enhance Cardiovascular Health: A Scoping Review Elsadai, Elsadai; Trisyani, Yanny; Nuraeni, Aan
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.553

Abstract

Cardiovascular disease (CVD) remains the leading cause of mortality globally and in Indonesia, with rising incidence among younger populations due to modifiable risk factors such as poor diet, physical inactivity, and mental health issues. These lifestyle-related factors are increasingly prevalent, yet interventions addressing them are varied and dispersed across the literature. To explore recent nutritional, physical activity, and mental health interventions for the prevention of cardiovascular disease. This study used a scoping review design. Articles were obtained from six databases, EBSCO-host, CINAHL, PubMed, ScienceDirect, Scopus, Taylor and Francis, and Google Scholar, with the major keywords “dietary”, “physical activity”, “mental health”, “cardiovascular disease”, “prevention”. Inclusion criteria included original studies, in English, published between 2015–2025, and the population reviewed was Adults / General population / High-risk individuals (e.g., aged >30, person with history of CVD). Data extraction followed the PRISMA-ScR guidelines. Twelve articles meeting the inclusion criteria showed intervention of prevention of cardiovascular disease. Physical activities such as walking, yoga, and exercise programs effectively improve cardiovascular health and physical fitness. Nutritional approaches like the Mediterranean diet help reduce cholesterol levels and blood pressure. Mental health practices, including meditation and stress management, contribute to lowering anxiety and blood pressure.  This review emphasizes that integrating regular physical activity, a nutritious diet, and mental health support is essential for effectively preventing cardiovascular disease, with personalized approaches playing a key role in helping individuals maintain these healthy habits.
Proximate and Phytochemical Composition of Bajakah (Spatholobus littoralis Hassk) Extract and its Effect on Fasting Blood Glucose in STZ-HFD-Induced Diabetic Rats Dara, Rizki Wulan; Lisyawati, Shanti; Febrinasari, Ratih Puspita
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.558

Abstract

The rising global prevalence of type 2 diabetes mellitus (T2DM) highlights the urgent need for plant-based therapeutic alternatives. Spatholobus littoralis Hassk, locally known as Bajakah, is a traditional medicinal plant from West Kalimantan, Indonesia, that is widely used by indigenous communities for regulating blood sugar levels. This study aimed to characterize the proximate and phytochemical composition of Bajakah wood extract and evaluate its antidiabetic potential in rats induced with a high-fat diet (HFD) and Streptozotocin (STZ). The extraction was performed using a 70% ethanol maceration method. Proximate analysis revealed low moisture (4.57%), ash (0.54%), total fat (0.81%), and protein (0.41%), with carbohydrates being the most abundant component (6.67%). Phytochemical screening using UV-Vis spectrophotometry identified total phenols (12.98%), flavonoids (1.16%), tannins (1.65%), and saponins (0.13%). The in vivo test on diabetic rats showed that the administration of Bajakah extract at a dose of 150 mg/kg body weight (BW) for 14 days significantly reduced fasting blood glucose levels from 279.46 ± 2.39 mg/dL to 115.62 ± 13.73 mg/dL (P= 0,028), corresponding to a 58,6% reduction. This reduction was greater than that of the positive control group, which was treated with Acarbose. The high content of phenolics and other bioactive compounds is strongly suggested to contribute to the antihyperglycemic effect through antioxidant mechanisms, inhibition of digestive enzymes, and enhancement of insulin sensitivity. This study these findings support the therapeutic potential of Bajakah wood extract from West Kalimantan as a complementary agent for management of T2DM.
The Types of Support That Enhance Body Image in Patients with Breast Cancer: A Scoping Review Christaputri, Silvia Tri Wahyu; Triyanto, Arifin; Tsauroh, Salsabila Fiqrotu; Mulyainuningsih, Wa Ode Saridewi; Effendy, Christantie
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.559

Abstract

Patients with breast cancer often experience dissatisfaction with themselves as a result of the treatment process they undergo, potentially resulting in a negative body image and affecting the effectiveness of treatment and their quality of life. Therefore, support is needed to address this issue. This study aims to identify the types of support that can be provided to improve body image in patients with breast cancer through a scoping review. We conducted a search using five databases, including ScienceDirect, Wiley, Scopus, ClinicalKey, and ProQuest. The inclusion criteria used were English-language articles and original research articles published between January 2020 and May 2025. Review articles, books, and pilot studies were excluded. The screening procedure was conducted in accordance with the PRISMA 2020 guidelines, and article eligibility was assessed by three researchers using the JBI Critical Appraisal Checklist (2020). Ten articles were obtained, indicating that various forms of support can be provided, such as social support (from family, friends, prominent figures, important or special people, and health workers); partner support; psychological support carried out through clinical interventions; and support from groups of fellow breast cancer survivors, but social support from family being the most commonly implemented form. This support helps patients in the process of improving body image that has changed due to the treatment process; however, in practice, the provision of a single type of support cannot stand alone. These findings affirm that providing support to enhance a positive body image in patients requires thorough attention. Further research is expected to explore the effectiveness of each type of support and involve more than one form of support to produce more comprehensive findings.
End-of-Life Acceptance in Hemodialysis Patients: A Conceptual Analysis Wabula, La Rakhmat; Yetti, Krisna; Masfuri, Masfuri; Widyatuti, Widyatuti; Widyawati, Ika Yuni; Septiwi, Cahyu
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.561

Abstract

End-of-life (EOL) acceptance is a crucial but underexplored concept among patients with end-stage renal disease (ESRD) undergoing hemodialysis. This study aimed to analyze and clarify the concept of EOL acceptance in hemodialysis patients using Walker and Avant’s eight-step method. These patients often face progressive physical deterioration and limited life expectancy, making psychological, emotional, and spiritual readiness to confront death a fundamental component of care. However, the term “EOL acceptance” lacks conceptual clarity and consistency in nursing practice. A comprehensive literature review was conducted using PubMed, CINAHL, and Scopus databases, targeting studies published between 2014 and 2024. The keywords used included ‘end-of-life,’ ‘terminal care,’ ‘death acceptance,’ ‘dying acceptance,’ ‘hemodialysis,’ ‘end-stage renal disease,’ and ‘terminal care nursing’. The analysis identified three attributes of EOL acceptance:  psychological readiness to face death, integration of existential and spiritual meaning, and proactive decision-making toward dignified dying. Supporting factors include awareness of terminal illness, therapeutic communication, and psychosocial-spiritual support. The identified consequences are emotional peace, enhanced family preparation, and improved quality of life. This analysis delineates a conceptual framework for EOL acceptance, enabling nurses to assess and support patients facing terminal illness effectively. It also provides a foundational framework for developing assessment tools and nursing interventions to improve person-centered EOL care for individuals with ERSD.
Modulation of GLUT4 and FOXO1 Expression by SH-MSC and Alkaline Water in Experimental Type 2 Diabetes Mellitus Fatmawati, Dian; Putra, Agung; Setiawan, Eko
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.562

Abstract

Type 2 Diabetes Mellitus (T2DM) is a metabolic disorder characterized by insulin resistance, which is associated with the dysregulation of glucose transporter 4 (GLUT4) and forkhead box protein O1 (FOXO1). The secretome from hypoxia-preconditioned mesenchymal stem cells (SH-MSC) and alkaline water have been proposed as potential therapies to modulate these molecular targets and improve glycemic control; however, their combined effects remain unexplored.  Using an experimental post-test-only control group design, this study aimed to assess the possible additive effect of SH-MSC and alkaline water on the expression of GLUT4 and FOXO1 in Wistar rats with type 2 diabetes. Twenty-five male Wistar rats were split into five groups: healthy control (G1), T2DM control (G2), T2DM with metformin (G3), T2DM with SH-MSC (G4), and T2DM with SH-MSC and alkaline water (G5).  Streptozotocin and nicotinamide were utilized to induce T2DM, and qRT-PCR was used to measure the expression of GLUT4 and FOXO1 in pancreatic tissue. One-way ANOVA and a post hoc LSD test were used for statistical analysis. The findings recognized that while GLUT4 expression was decreased, T2DM induction markedly increased fasting blood glucose levels and FOXO1 expression. SH-MSC treatment significantly upregulated GLUT4 and downregulated FOXO1 equated to the control T2DM group, and while the addition of alkaline water showed a further trend of improvement, this difference was not statistically significant. These findings suggest that SH-MSC therapy effectively improves glucose metabolism by modulating GLUT4 and FOXO1 expression, with the potential for alkaline water as an adjunctive therapy in T2DM management
In Vivo Evaluation of Butterfly Pea (Clitoria ternatea) Flower Gel on IL-10 and STAT3 Expression in Thermally Induced Skin Burns Mediana, Mecha Amalia; Hussaana, Atina; Trisnadi, Setyo
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.563

Abstract

Burn injuries caused by thermal exposure trigger oxidative stress and inflammation, largely driven by reactive oxygen species (ROS) and systemic inflammatory response syndrome (SIRS). These mechanisms may disrupt the production of cytokines involved in tissue repair, such as interleukin-10 (IL-10) and signal transducer and activator of transcription 3 (STAT3). Clitoria ternatea L. (butterfly pea) contains potent antioxidant and anti-inflammatory phytochemicals, making it a promising candidate for modulating inflammatory responses and promoting wound healing. This study evaluated the effects of Clitoria ternatea extract gel on IL-10 and STAT3 expression in second-degree burn injuries using a Wistar rat (Rattus norvegicus) model. A post-test only control group design was employed, involving 30 male rats randomly assigned to five groups (G1–G5). Second-degree burns were induced using a 1.8 cm diameter heated metal plate applied to the dorsal skin for 3 seconds after heating for 15 minutes. Treatments with the extract gel were administered topically for seven days. Skin samples were collected 24 hours after the last application and analyzed for IL-10 and STAT3 mRNA expression using qRT-PCR. Data were statistically tested with One-Way ANOVA. The results showed no significant differences in IL-10 expression among all groups. However, STAT3 expression was significantly higher in the groups treated with 5% and 10% Clitoria ternatea extract gel, with the highest observed in the 10% group (6.73 ± 2.94). These findings indicate that while IL-10 remained unaffected, butterfly pea extract gel effectively increased STAT3 expression, suggesting its potential role in modulating regenerative pathways in burn-injured skin
Analysis of the Implementation of Mental Health Screening of Pregnant Women by Midwives in Bantul Regency, Yogyakarta: A Mixed Methods Study Rohani, Rohani; Pratiwi, Cesa Septiana; Sarwinanti, Sarwinanti
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.564

Abstract

Mental health disorders during pregnancy are a very important issue for maternal and fetal health. Screening for conditions such as depression and anxiety is needed, but often overlooked in Indonesia. This study aims to analyze the implementation of mental health screening of pregnant women by midwives in Bantul Regency, Yogyakarta. This study used a mixed methods approach   with a sequential explanatory approach consisting of a quantitative online survey followed by qualitative FGDs. The results of the study showed that 115 midwives 67.0% only screened less than 25% of the total pregnant women they served. Only a small proportion conducted routine screening (13.0% 5-10 times, and 14.8% more than 10 times). Qualitative findings from 12 midwives confirmed that while screening can identify mental health concerns, its application is inconsistent and faces substantial barriers, including limited time, privacy, insufficient training, and lack of screening tools. Despite these challenges, midwives showed a generally positive perception of the importance of mental health screening for both mothers and fetuses. Supporting factors for screening include policy, education, integrated services, professional collaboration, SOPs, and additional human resources. In conclusion, this study highlights gaps in mental health screening practices and emphasizes the importance of improving training, access to screening tools, and supportive policies. Further research is needed to explore strategies for addressing these barriers and consider the role of technology, while multicenter studies could be conducted to expand the scope of this study, making the results more representative
Predictors of Central Obesity in Perimenopausal Women: An Analysis of Food Craving, Diet Quality, and Physical Activity Mahardika Yudianti, Manda Talitha; Kusnandar, Kusnandar; Widyaningsih, Vitri
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.566

Abstract

Central obesity, an accumulation of abdominal fat, which can be measured using waist circumference, is a health risk that may increase during the perimenopausal transition. Central obesity is caused by various factors, which include, environmental and behavioral factors (physical activity and eating behavior). Eating behaviors that contribute to obesity include a strong desire to consume certain types of food/food craving. Poor eating habits such as consuming high-calorie foods, fast food consumption, and not consuming a variety of foods will affect one's diet quality. This cross-sectional study with multistage sampling method collected data from 125 women with perimenopausal symptoms. Data were collected via interviewer-administered validated questionnaires. Statistical analysis was conducted using SPSS software 25. The results indicated that 63.2% of the respondents had central obesity, 40,5% of those sometimes experienced food cravings. Most respondents with central obesity (94,9%) and non-central obesity (84,8%) had a very poor diet quality, and 40,5% of respondents with central obesity had vigorous activity, compared to 47.8% among women without central obesity. There was significant correlation between food craving (OR = 1.091; 95% CI = 1,04 – 1,14), diet quality (OR = 0.916; 95% CI = 0,86 – 0,96) with central obesity (p<0,05). There was no significant correlation between physical activity, education level, and socioeconomic status with central obesity (p>0,05). In conclusion, diet quality and food craving significantly influence the incidence of central obesity in women with perimenopausal symptoms in Bukittinggi City.
Air Quality and Its Effects on Acute Respiratory Infections Among Children Under Five in Jambi City: A Generalized Additive Model Approach Sitanggang, Hendra Dhermawan; Kalsum, Ummi; Putra, Ashar Nuzulul
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.573

Abstract

Acute Respiratory Infections (ARI) are the leading cause of morbidity and mortality among children under five and a common reason for health service visits. The World Health Organization (WHO) recognizes air pollution as the greatest environmental threat to human health, including ARI risk. In Jambi City, the prevalence of ARI among children under five remains high, while air quality is of concern due to motor vehicle emissions, open waste burning, and forest fires. Air quality can have direct and indirect effects on ARI incidence. Previous studies in Jambi have analyzed ARI using individual-level data; research on broader patterns, trends, and air quality influence remains limited. This study aims to analyze the influence of air quality on ARI incidence in children under five in Jambi City. The study was a time series using monthly data on ARI prevalence, PM10, SO2, CO, O3, temperature, humidity, and rainfall. The results showed ARI cases were high at the beginning and end of each year, fluctuating from 2021 to 2023 with a marked increase in 2023. The final GAM model indicated a significant negative linear association for PM10 (p=0.04) and humidity (p=0.03). Carbon monoxide (CO) demonstrated a significant non-linear effect (edf=4.01, p=0.0005). Time (month), representing seasonal and long-term trends, showed the strongest non-linear association (edf=7.9, p=0.0001), reflecting seasonal variation in ARI incidence. Efforts are needed to raise awareness about ambient air quality, particularly PM10 and CO, so that parents remain vigilant outdoors with children. These findings highlight the importance of interventions, including emission control and education, to reduce ARI risk in under-five children.