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Jurnal Ventilator: Jurnal Riset Ilmu Kesehatan dan Keperawatan
Published by Sekolah Tinggi Ilmu Kesehatan Kesdam IV, Diponegoro
ISSN : 2986786X     EISSN : 29867088     DOI : 10.59680
Core Subject : Health,
Health Professions Nursing Public Health
Bidang kesehatan dan keperawatan termasuk penelitian dasar dalamkesehatan dan keperawatan, keperawatan manajemen, keadaan darurat, dan keperawatan kritis, keperawatan medis-bedah, keperawatan kesehatan mental, keperawatan maternitas, keperawatan Anak, gerontologis keperawatan, keperawatan komunitas, keperawatan pendidikan keperawatan keluarga, pengobatan komplementer dan alternatif (CAMs, Complementary and alternative medicines) dalam keperawatan.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 426 Documents
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Efektivitas Senyawa Sulforaphane dari Microgreen Brokoli (Brassica Oleracea) sebagai Immunomodulator (Anti-Pyroptosis Macrophage) dan Antifibrosis Paru untuk Pengobatan Penyakit Tuberkulosis Paru Nohan Noer Adnan; Naufal Issan Beryldivito Iskandar; Ganesha Galang Yudistira
Jurnal Ventilator Vol. 4 No. 2 (2026): Juni : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i2.2491

Abstract

Pulmonary tuberculosis is a contagious infectious disease caused by Mycobacterium tuberculosis and remains one of the leading causes of death worldwide, including in Indonesia. Long-term tuberculosis treatment often results in various problems, such as drug resistance, poor patient adherence, lung tissue damage, and post-infection pulmonary fibrosis. Therefore, innovative natural-based therapeutic approaches are needed to improve treatment effectiveness while minimizing complications. This study aims to examine the potential of sulforaphane (SFN), a phytochemical compound derived from broccoli microgreens (Brassica oleracea), as an immunomodulatory and anti-pulmonary fibrosis agent through nanoencapsulation technology. This study employed a narrative literature review method using scientific databases, including PubMed, Scopus, ScienceDirect, and Google Scholar, covering publications from 2018–2024. Data were analyzed using critical appraisal techniques to systematically evaluate and synthesize previous findings. The review demonstrated that SFN exhibits antioxidant activity by activating the NRF2 signaling pathway, thereby reducing reactive oxygen species (ROS) production, inhibiting NLRP3 inflammasome activation, and preventing macrophage pyroptosis induced by M. 
MICROMETRICS: Teknik Diagnosis Portable Kanker Kolorektal Menggunakan Biomarker MiR-21 Berbasis Point-of-Care Testing (POCT) dengan Metode Colorimetry melalui Nanoparticle-Based Assay Naufal Issan Beryldivito Iskandar; Nohan Noer Adnan; Ganesha Galang Yudistira
Jurnal Ventilator Vol. 4 No. 2 (2026): Juni : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i2.2492

Abstract

Colorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide and remains the second leading cause of cancer-related mortality. Delayed screening significantly contributes to the high mortality rate of CRC. Current screening methods, such as colonoscopy and Fecal Immunochemical Testing (FIT), are considered gold standards; however, these approaches are invasive, costly, and may cause discomfort or intestinal injury. Therefore, the development of a minimally invasive, affordable, and portable diagnostic method is urgently needed. This study proposes MICROMETRICS, a smartphone-based Point-of-Care Testing (POCT) innovation designed to detect miR-21, a promising biomarker for colorectal cancer, using a colorimetric nanoparticle-based assay. The study employed a literature review method using scientific databases, including PubMed, Google Scholar, ResearchGate, and ScienceDirect. Data were analyzed through descriptive and critical appraisal approaches to design a low-fidelity prototype and evaluate its feasibility using SWOT analysis. The MICROMETRICS system integrates a mini-laboratory hardware setup with smartphone software capable of analyzing color changes generated by interactions between miR-21 and metallic nanoparticles. The captured images are processed through RGB-to-CIELAB color conversion and mathematical algorithms to determine miR-21 concentration quantitatively. The results are then displayed graphically in real time through the application interface. Elevated miR-21 concentrations indicate a positive CRC screening result. Overall, MICROMETRICS demonstrates strong potential as a flexible, cost-effective, rapid, and minimally invasive diagnostic platform for colorectal cancer screening and early detection, particularly in resource-limited healthcare settings.
Epidural Blood Patch for Severe Post-Dural Puncture Headache in a Hypertensive Patient Following Spinal Anesthesia: A Case Report Maulfi Natsir Asy’ari; Yosie Arief Sanjaya; Nafi Ilhamsyah; Alfi Sachdeva Aziz Waktar; Arsya Malika Arief
Jurnal Ventilator Vol. 4 No. 1 (2026): Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i1.2495

Abstract

Post-dural puncture headache (PDPH) is a frequent complication following neuraxial anesthesia, resulting from cerebrospinal fluid (CSF) leakage and intracranial hypotension. Although typically self-limiting, severe PDPH can significantly impair patient function and delay recovery. Epidural blood patch (EBP) is considered the gold standard treatment for refractory cases; however, optimal volume and clinical considerations in patients with comorbidities such as hypertension remain underreported. We report a 45-year-old female with a history of hypertension who developed severe PDPH following spinal anesthesia for lymphadenectomy. The procedure required multiple attempts using a 25G Quincke needle. Within hours postoperatively, the patient experienced a classic orthostatic headache accompanied by photophobia, nausea, and inability to tolerate an upright position. Conservative management failed to provide improvement after 48 hours. An epidural blood patch using 10 mL of autologous blood was subsequently performed, resulting in rapid and significant symptom relief within one hour, followed by progressive clinical recovery over the next two days. This case highlights the importance of early recognition and timely intervention in PDPH, particularly in patients with overlapping symptoms such as hypertension. Notably, a lower-volume EBP (10 mL) demonstrated effective clinical outcomes, suggesting that individualized approaches may be sufficient in selected patients. Epidural blood patch remains a safe and effective definitive treatment for refractory PDPH.
Efektivitas Senam Hamil dan Prenatal Yoga Terhadap Nyeri Punggung Ibu Hamil Trimester III Ulin Nafiah; Amin Fatayati; Sony Factarun
Jurnal Ventilator Vol. 4 No. 2 (2026): Juni : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i2.2502

Abstract

Back pain is one of the most common complaints experienced by pregnant women, especially during the third trimester. The increasing size of the uterus shifts the body's center of gravity forward, causing postural changes such as lumbar lordosis that contribute to back pain. This study aimed to determine the effectiveness of pregnancy exercises and prenatal yoga in reducing back pain among third-trimester pregnant women and to compare the effectiveness of both interventions. A quasi-experimental study with a two-group pretest-posttest design was conducted involving 18 third-trimester pregnant women experiencing back pain. Participants were selected using a simple random sampling technique. The independent variables were pregnancy exercises and prenatal yoga, while the dependent variable was back pain intensity measured using the Numeric Rating Scale (NRS). Data were analyzed using the Wilcoxon test and Mann–Whitney test with a significance level of 0.05. The Wilcoxon test results showed significant reductions in back pain after pregnancy exercises (p = 0.000) and prenatal yoga (p = 0.000). The Mann–Whitney test demonstrated a significant difference in effectiveness between the two interventions (p = 0.027). Mean rank analysis indicated that prenatal yoga (22.17) was more effective than pregnancy exercises (14.83) in reducing back pain. In conclusion, both pregnancy exercises and prenatal yoga are effective non-pharmacological interventions for reducing back pain in third-trimester pregnant women, with prenatal yoga showing greater effectiveness.
Pengaruh Dynamic Neuromuscular Stabilization (DNS) terhadap Aktivitas Otot Multifidus pada Low Back Pain Astrid Komala Dewi; Catherine Hermawan Salim; Ria Efkelin
Jurnal Ventilator Vol. 4 No. 2 (2026): Juni : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i2.2504

Abstract

Low Back Pain (LBP) is one of the most common musculoskeletal disorders and is closely associated with decreased segmental stability of the spine. The multifidus muscle plays an important role in maintaining lumbar stability; however, patients with LBP frequently exhibit reduced activation and neuromuscular control of this muscle. Dynamic Neuromuscular Stabilization (DNS) is an exercise approach based on developmental kinesiology that aims to optimize the coordination and activation of deep stabilizing muscles. This study aimed to determine the effect of Dynamic Neuromuscular Stabilization on multifidus muscle activity in patients with Low Back Pain. The research employed a quasi-experimental design with a pretest–posttest approach. The study subjects were patients with non-specific Low Back Pain who met the inclusion and exclusion criteria. DNS intervention was administered for 4–6 weeks with a frequency of 2–3 sessions per week. Multifidus muscle activity was measured using electromyography (EMG) before and after the intervention. Data were analyzed using a paired t-test or Wilcoxon test according to data distribution. The results demonstrated a significant increase in multifidus muscle activity following DNS intervention (p < 0.05). In conclusion, Dynamic Neuromuscular Stabilization has a positive effect on increasing multifidus muscle activity in patients with Low Back Pain and can therefore be recommended as a physiotherapy intervention to improve lumbar stability and reduce the risk of pain recurrence.
Tinjauan Literatur Determinan Pemilihan Kontrasepsi Intra Uterine Device (IUD) pada Wanita Usia Subur Darah Ifalahma; Ana Yuliana; Risma Nurul Istiqomah; Reni Dika Wardani
Jurnal Ventilator Vol. 4 No. 2 (2026): Juni : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i2.2510

Abstract

The intra uterine device (IUD) is one of the most effective long-term contraceptive methods for preventing pregnancy. However, various studies show that IUD low utilization rates are influenced by multiple determinants, both internal and external. This literature review aims to analyze the internal and external factors that contribute to IUD use among women of reproductive age. The method used was a systematic literature review of five national journals published between 2018–2023, obtained from Garuda, Google Scholar, and DOAJ databases. The internal factors identified include age, education, parity, knowledge, attitude, occupation, and income. External factors include husband’s support, health workers’ support, availability of contraceptive facilities, and access to reproductive health services. The findings reveal that knowledge and attitude are the most dominant internal factors, while husband’s support and the role of health workers are the main external factors influencing IUD success and continuity. Strengthening counseling, empowering women through education, and involving partners are crucial to minimize IUD failure and improve contraceptive effectiveness.
Analisis Faktor-Faktor yang Memengaruhi Kesejahteraan Psikologis dan Tingkat Kecemasan Ibu Hamil: Sebuah Tinjauan Literatur Siti Zulhijjah; Nurul Wahidah; Martina Astari; Theresia Shella Beredikta; Sesilia Triana Dewi
Jurnal Ventilator Vol. 4 No. 2 (2026): Juni : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i2.2512

Abstract

Mental health during pregnancy is an essential aspect of maternal well-being that often receives less attention than physical health. Psychological problems experienced during pregnancy, such as anxiety, stress, and depression, can negatively affect both maternal and fetal health outcomes. Therefore, understanding the factors that influence the psychological well-being of pregnant women is important for developing effective interventions and support systems. This study aimed to identify the dominant factors influencing the psychological well-being of pregnant women through a literature review of 20 relevant research articles. The review was conducted using journal searches from the Google Scholar database and the Garuda Portal. Articles were selected based on their relevance to maternal mental health during pregnancy and were analyzed to identify common findings related to psychological well-being. The results of the review revealed that several factors significantly influence the mental health of pregnant women. Social support from partners, family members, and healthcare providers was identified as the most influential protective factor. In addition, maternal age, economic status, educational level, and pregnancy-related complications were found to affect anxiety and stress levels. The findings suggest that psychosocial interventions and strong partner support play a vital role in reducing the risk of antenatal depression and promoting better mental health during pregnancy.
Peran Conjugated Linoleic Acid (CLA) dalam Susu terhadap Aktivitas Antioksidan dan Kesehatan Metabolik: Tinjauan Literatur Alfuu Nur Harahap; Luluk Hermawati; Rizky Kusuma Wardani; Kenny Cantika Abadi
Jurnal Ventilator Vol. 4 No. 3 (2026): September : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i3.2516

Abstract

Milk is a functional food containing various bioactive compounds, one of which is Conjugated Linoleic Acid (CLA), which is known to possess antioxidant activity and play a role in lipid metabolism regulation. CLA is a group of polyunsaturated fatty acids naturally formed through the biohydrogenation process in the rumen of ruminant animals and is commonly found in milk and dairy products. This article aimed to review the role of CLA in milk on antioxidant activity and metabolic health based on recent literature studies. This study was conducted using a narrative literature review method through article searches in the PubMed and ScienceDirect databases published between 2015 and 2025 using keywords related to CLA, milk, antioxidant activity, and metabolic health. The initial search identified 3,357 articles. After the selection process based on topic relevance, full-text availability, and content suitability, 22 articles were included in this review. The findings showed that CLA could increase antioxidant enzyme activity, reduce oxidative stress, improve lipid profiles, and support metabolic and cardiovascular health. Therefore, CLA has the potential to be developed as a functional food component beneficial to health.
Hubungan Pola Konsumsi Makanan Keluarga dengan Status Gizi Balita di Kelurahan Dawi-Dawi Kecamatan Pomalaa Ekawati Saputri; Rosmiati Rosmiati
Jurnal Ventilator Vol. 4 No. 2 (2026): Juni : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i2.2517

Abstract

Nutritional status in toddlers is an important indicator of child health and growth, which can be influenced by family dietary consumption patterns. This study aimed to analyze the relationship between family food consumption patterns and the nutritional status of toddlers in Dawi-Dawi Village, Pomalaa District. This research used a quantitative analytic observational design with a cross-sectional approach. The sample consisted of 24 mothers or caregivers of toddlers aged 12–59 months selected using total sampling technique. Data on food consumption patterns were collected using a Food Frequency Questionnaire (FFQ) and 24-hour dietary recall, while nutritional status was measured using anthropometric assessments based on weight-for-age index (W/A). Data were analyzed using univariate, bivariate, and multivariate logistic regression analyses. The results showed that there was no statistically significant relationship between meal frequency, dietary diversity, 24-hour nutrient intake, and family food consumption patterns with the nutritional status of toddlers (p>0.05). However, toddlers with poor food consumption patterns had a 3.57 times greater risk of having abnormal nutritional status. Multivariate analysis indicated that food consumption pattern was the most dominant factor associated with toddler nutritional status after controlling for infectious disease history (OR=7.50; p=0.158). In conclusion, family food consumption patterns remain an important factor influencing toddler nutritional status, although the statistical association was not significant. Therefore, improving parental knowledge regarding balanced and diverse nutrition is necessary to support optimal child growth and development.
Hubungan Konsumsi Suplemen Multiple Micronutrient Supplement (MMS) pada Masa Kehamilan terhadap Berat Badan Lahir Bayi di RSUD Dr. M.M. Dunda Limboto Fegi Indriyani Suleman; Harismayanti Harismayanti; Fahmi A. Lihu
Jurnal Ventilator Vol. 4 No. 2 (2026): Juni : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i2.2522

Abstract

Low Birth Weight (LBW) remains a global health issue associated with an increased risk of neonatal morbidity and mortality. One strategy for preventing LBW is ensuring adequate micronutrient intake during pregnancy through the consumption of Multiple Micronutrient Supplements (MMS). This study aims to determine the relationship between MMS consumption during pregnancy and infant birth weight at Dr. M.M. Dunda Limboto Regional General Hospital. This study used a quantitative observational analytical design with a retrospective cross-sectional approach. The study population consisted of mothers who gave birth at Dr. M.M. Dunda Limboto Regional General Hospital, with a sample size of 42 respondents selected using purposive sampling. Data were collected from secondary sources, including medical records and the Maternal and Child Health (MCH) Book, and analyzed using the chi-square test. The results showed that the majority of respondents adhered to taking MMS, totaling 25 respondents (59.5%), while 17 respondents (40.5%) did not adhere. Based on birth weight, 28 infants (66.7%) had normal birth weight, and 14 infants (33.3%) were low birth weight (LBW). The results of the Chi-Square test showed a p-value of 0.000 (p<0.05), indicating a significant association between MMS intake and infant birth weight. Pregnant women who adhered to MMS intake were more likely to give birth to infants with normal birth weight compared to those who did not adhere. The conclusion of this study is that there is a significant association between MMS intake during pregnancy and infant birth weight. Adherence to MMS intake needs to be improved through education and routine monitoring during pregnancy.

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