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Dermatology and Venereology Department, Medical Faculty, Universitas Udayana/Prof. dr. I G. N. G. Ngoerah General Hospital, 3rd Floor (Jl. Diponegoro, Dauh Puri Klod, Kecamatan Denpasar Barat, Kota Denpasar, Bali 80113)
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Bali Dermatology Venereology and Aesthetic Journal
Published by Universitas Udayana
ISSN : 30467985     EISSN : 30467993     DOI : https://doi.org/10.51559/balidervenaesthj.v6i1.33
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Bali Dermatology Venereology and Aesthetic Journal is an open access; peer-reviewed journal aiming to communicate high-quality research articles, reviews, and general articles in the Dermatology, Venereology and Aesthetic field. The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of Dermatology, Venereology and Aesthetic and to encourage a vigorous dialogue between researcher, medical scholars and practitioners. The scope of this journal includes: General dermatology Venereology Cosmetic dermatology/aesthetic Pediatric dermatology Allergy and immunology Skin and tumor surgery Tropical dermatology Genodermatosis (hereditary skin disease) Travel dermatology Traditional, Complementary, and Integrative medicine in dermatology Diagnostic method and artificial intelligence in dermatology
Arjuna Subject : Kedokteran - Dematologi
Articles 75 Documents
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Case report of a 28 years old woman with lepromatous leprosy mimicking systemic lupus erythematosus Wijaya, Edward; Komarasari, Eka; Esti, Prima Kartika
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 7, Issue 1 (January 2024)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v7i1.87

Abstract

Background: Leprosy has been known as the greatest imitator disease that can mimic a disease condition, including autoimmune disease. This case report aims to demonstrate and remind healthcare providers that leprosy infection may manifest with various autoimmune phenomena reminiscent of classic autoimmune disease, including systemic lupus erythematosus (SLE), and to prevent delayed treatment and further complications. Case report: A 28-year-old female patient with ulcers all over her body and amputation of her fingers and toes. Based on the positive antinuclear antibodies (ANA) test results, weak positive ANA profile band, anticardiolipin antibodies immunoglobulin M (ACA IgM), and complement C4 test, the patient has been diagnosed with systemic lupus erythematosus (SLE) since eleven years ago. There was no improvement during SLE therapy as the years passed. The patient developed leprosy symptoms such as madarosis, saddle nose, and facies leonine. Slit skin smear for leprosy acid-fast bacilli (AFB) from forehead and chin showed bacterial index +6, skin biopsy examination concluded lepromatous leprosy with bacterial index +5, and IgM anti-PGL-1 serological test examination 3185 u/ml. She was treated with steroids at the hospital and multidrug therapy for multibacillary leprosy (MDT MB) for one year. She had significant improvement after receiving medication. Conclusion: The diagnosis of leprosy is delayed because of the clinical similarities between the disease and SLE. The clinicians should know leprosy-specific symptoms to avoid inaccurate diagnoses and treatment delays.
Dermatomyositis with multiple organ involvement: a case report and literature review Putri, Wayan Julita Krisnanti; Wardiana, Maya; Anindita, Karina; Putri, Adisti Prafica; Kumaladewi, Baiq Ratna; Santosa, Hilda
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 6, Issue 2 (December 2023)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/4x0xd735

Abstract

Background: Dermatomyositis (DM) is a chronic autoimmune disorder characterized by muscle and skin inflammation, a part of the idiopathic inflammatory myositis (IIM). Even though the disease is idiopathic, there are multifactorial factors related to dermatomyositis. This care report aimed to describe a DM case in a male patient to increase the knowledge and management of DM patients. Case description: A 44-year-old Filipino male was referred to the emergency department (ED) of Siloam Hospital Mataram complaining of muscle pain and weakness with skin rashes 3 weeks before admission. Before the skin rash started, he had enlarged femoral lymph nodes in both thighs. The patient was afebrile with normal vital signs and was prescribed ibuprofen and amoxicillin. After that, he experienced skin rashes around his neck and the back of his ears with minimal pruritus.  The symptoms worsened, making him unable to open his mouth and hard to breathe. In the ED, he also threw up dark-colored blood twice. Supporting examination showed elevated transaminase, increased LDH, and creatinine kinase. Biopsy results showed a histologic pattern of dermatomyositis. During hospitalization, he received a high-dose systemic steroid, antibiotic, and symptomatic treatment. He was discharged with a good outcome and planned to continue medical treatment in his country. Conclusion: Dermatomyositis is an idiopathic autoimmune disease involving skin and internal organs. It is a multifactorial disease yet with unclear etiopathogenesis. Specific treatment guidelines for DM are not yet established, but initial systemic corticosteroid and additional steroid-sparring agents may exhibit good outcomes.
Characteristics of syphilis in the Dermato-Venereology Department of Bali Mandara General Hospital Octaviani, Elrica Stella; Wahyuni, Luh Putu Dina
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 7, Issue 1 (January 2024)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v7i1.92

Abstract

Introduction: Treponema pallidum is the sexually transmitted pathogen that causes syphilis. Congenital or acquired syphilis are the two categories. In 2020, the World Health Organization (WHO) anticipates 7 million additional cases of syphilis. 76,923 new patients were reported in 2020 by the Ministry of Health of the Republic of Indonesia. There is still inadequate information about Bali's incidence or prevalence of syphilis. This study aims to describe the characteristics of syphilis patients seeking treatment at Bali Mandara Hospital's Dermato-Venereology Department between 1st January 2020 to 31st December 2022. Methods: In this descriptive cross-sectional retrospective study from 1st January 2020 to 31st December 2022, we used 56 samples from secondary data collected from the patient register book and medical records of the dermatovenereology outpatient clinic at Bali Mandara General Hospital. Data were analyzed descriptively using SPSS version 26. Results: According to the study, there were 56 syphilis patients, including 32 men (57.1%) and 24 women (42.9%). The most common age group was 25 to 44 years old, with 36 patients (64.3%), while the most common clinical stage of syphilis was early latent syphilis, with 20 patients (35.7%). Venereal Disease Research Laboratory (VDRL) titer of 1:2 was the most frequent finding, with 16 patients (28.6%). Conclusion: It may be concluded that syphilis cases at Bali Mandara General Hospital have a different description that varies according to each variable. Future studies on syphilis cases are anticipated to build on the findings of this study.
The combination of Q-switched neodymium:yttrium–aluminum–garnet (Nd:YAG) laser with photoacoustic pulse technology in combination with polynucleotides (PN) salmon DNA for skin rejuvenation: A case series Setiawan , Stanley; Handayani , Theressia; Luziani, Stefani
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 7, Issue 1 (January 2024)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v7i1.95

Abstract

Background: Skin aging leads to dyspigmentation, wrinkles, and lentigines. Photorejuvenation, especially Q-switched Nd:YAG laser therapy, is commonly used to address these concerns. We present a case series evaluating the effectiveness of combining Q-switched Nd:YAG laser with Polynucleotides (PN) Salmon DNA for facial photorejuvenation. Case series: Five healthy adults underwent four sessions of full-face laser toning with a QS 1064 nm Nd:YAG laser followed by Polynucleotide (PN) Salmon DNA 2% injections every two weeks. We recorded subjective assessments and pain levels during treatment and captured photographic images for analysis. The treatment significantly improved skin brightness and pigmentation, with some subjects achieving mild or no pigmentation. Skin elasticity improvements varied among subjects. Some experienced significant enhancement, while others showed minor changes or none at all. Skin redness responses varied. Objective measurements revealed pore size, skin elasticity, moisture, skin tone, wrinkles, and skin age improvements. Conclusion: Combining Q-switched Nd:YAG laser with PN Salmon DNA shows promise for enhancing skin health and appearance.
The effectiveness of ceramide moisturizing cream in pruritic papular eruption treatment of HIV/AIDS patients Sayekti, Ayu Wikan; Putri, Ann Kautsarina; Pudjiati, Satiti Retno; Winarni, Dwi Retno Adi
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 7, Issue 1 (January 2024)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v7i1.96

Abstract

Background: Pruritic papular eruption (PPE) is one of the most common skin manifestations in HIV/AIDS patients. Pruritic papular eruptions are due to immune dysregulation, causing dominance of interleukin-4, which causes a decrease in ceramide synthesis (CER) and impaired skin barrier function. This study aimed to investigate the effectiveness of CER over non-CER moisturizing cream in HIV/AIDS patients with PPE. Methods: Double-blind experimental design. The research subjects are PPE patients at Dr. Sardjito General Hospital. CER and non-CER moisturizing cream are applied for three weeks, respectively. Analysis of the trans-epidermal water loss (TEWL), skin hydration, and itching were analyzed using an unpaired T-test or the Mann-Whitney test with a significance of p<0.05. Results: Ceramide synthesis moisturizing cream decreased the TEWL value by 3.56 ± 2.38 g/m2/hour; increased the value of skin hydration by 16.39±7.19 a.u.; decreased skin lesions by 0.79 ± 4.95; reduced itching by 1.54 ± 0.78 and without causing side effects. Non-CER moisturizing cream decreased the TEWL value by 1.57 ± 2.00 g/m2/hour; increased the value of skin hydration by 12.03 ± 6.88 a.u.; decreased skin lesions by 1.42 ± 3.00; reduced itching by 1.17 ± 0.70 and also without causing side effects. Conclusion: Ceramide cream is more effective than non-CER moisturizing cream in reducing TEWL and increasing skin hydration. Ceramide and non-CER moisturizing creams have the same effectiveness in reducing the number of lesions and reducing itching. Ceramide and non-CER moisturizing creams do not cause side effects.
A cross-sectional study on dermatology practice in general medicine: specialists’ referral, training needs and teledermatology in Morocco Ait Oussous, Sara; Chakiri, Radia
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 7, Issue 2 (July 2024)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v7i2.97

Abstract

Background: Demographic and geographic constraints make access to specialists difficult, reinforcing the role of general practitioners (GPs) in dermatology. The purpose was to investigate dermatology practice, referral patterns to dermatologists, training needs in this field, and their opinions on teledermatology. Methods: A survey questionnaire was randomly distributed through Google Forms among Moroccan GPs. The statistical analysis of the collected data was carried out using SPSS. Results: 189 responses were collected. The mean age was 41.2 years. 61.4% were female. The proportion of dermatological consultations in general practice was 10 to 20% in 42.9% of cases. Dermatological disorders were the main reason for consultation in 42.9% of cases. Approximately 75.6% of the GPs felt they were moderately or not proficient in dermatology. 64% were not satisfied with their initial training. 84.7% were interested in additional training courses dedicated mainly to inflammatory pathologies (82%), infectious diseases (78.8%), and facial dermatoses (71.4%). 64.6% favored teledermatology and saw it as interesting, mainly for obtaining a rapid diagnostic opinion (71.4%) and training through direct exchange with the specialist (67.7%). A multivariate analysis was performed using age, practice location, and recent continuing education. Conclusion: Our study has highlighted insufficient initial training for current practice and, therefore, a need for further training. This suboptimal diagnostic capacity would contribute to the increase in the dermatologist use by GPs. The development of teledermatology could respond to this problem.
Role of secretomes in chronic wound treatment: a review Limanda, Claudia Felicia; Intizam, Marwa Humaira; Augustin, Dara Cynthia
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 7, Issue 2 (July 2024)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v7i2.98

Abstract

Living with a chronic wound may prove to be devastating to patients both physically and psychologically. Wound increases economic and society burden due to low healing rate, prolonged hospital treatment, and increased epidemiology worldwide. Therefore, application wound treatment modalities are necessary for patient recovery. However, each modality has their own advantage and limitation. As a newly-founded modality, secretome, which originated from Mesenchymal stem cells (MSCs) plays an important role in chronic wound healing due to its ability in promoting tissue regeneration and self-renewal that supports cell proliferation and migration. However, different therapeutic potentials can arise according to each source of stem cells. This review highlights the importance of secretome as a modality in treating chronic wounds. Secretome types, stem cell origin, and results when applied in vitro and in vivo will also be comprehensively reviewed.
Adult-onset Henoch-Schonlein purpura: A case report Ruslan, Lettisia Amanda; Saraswati, Putu Dyah Ayu
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 7, Issue 2 (July 2024)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v7i2.99

Abstract

Background: Henoch-Schönlein purpura (HSP) is a cutaneous small vessel vasculitis that typically affects children under ten but may also occur in adults. This study aims to report a rare instance of an adult patient with HSP to expand our knowledge and prevent delayed diagnosis and treatment. Case: A 21-year-old female patient presented with palpable purpuric lesions on the lower abdomen, buttocks, and lower limbs. In addition, the patient complained of abdominal pain and joint pain. The patient had suffered an upper respiratory tract infection with spontaneous resolution three days before the skin lesions. Laboratory tests showed leukocytosis and elevated anti-Streptolysin O titer. The patient was diagnosed with HSP and given oral methylprednisolone, antibiotics, and symptomatic treatment. She showed clinical improvement after taking medication. Conclusion: Henoch-Schönlein purpura is typically a self-limiting disease and infrequent in adults, but it has the potential to manifest into life-threatening conditions such as end-stage renal failure. An integrated multidisciplinary approach is needed for early diagnosis and management.  
A case report of an elderly with herpes zoster and atrial fibrillation taking warfarin Putra, Gilang; Devina, Wilona; Priyadarshini, Ida Ayu Uttari
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 7, Issue 2 (July 2024)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v7i2.101

Abstract

Background: Herpes zoster (HZ) presents with unilateral dermatomal pain and rash resulting from the reactivation and proliferation of latent varicella zoster virus (VZV) that dwells in neurons following varicella. It mostly occurs in the elderly and in immunocompromised . Warfarin consumption can lead to dysregulation of cytokines that cause immune dysregulation, which can be a factor in the reactivation of herpes zoster. There is limited research or study exploring the correlation between herpes zoster reactivation and the use of warfarin in patients with atrial fibrillation This case report aim to investigate potential role of anticoagulant therapy, specifically warfarin, in the reactivation of HZ in elderly patients, and to explore the implications of polypharmacy and immune dysregulation in the management and prevention of HZ. Case Description: A 55-year-old male with a history of atrial fibrillation, currently on warfarin, was admitted with complaints of pain blister lession that developed 7 days post-discharge from the Cardiology department. His initial symptoms included pruritus and pain localized to the chest and right thoracic area. Dermatological examination revealed herpetiform vesicles on an erythematous base, accompanied by crusts and scabs, distributed along thoracic dermatomes T6-T8. Conclusion: Elderly patients often experience polypharmacy due to degenerative diseases. Cardiovascular treatment often includes anticoagulants such as warfarin. Following 1 week after the administration of topical antibiotic and steroid ointments, the patient demonstrated a positive clinical outcome with a few complications after HZ infection.    
Prevalence and characteristics of occupational contact dermatitis among farmers in Wongaye Gede Village, Tabanan, Bali Sunyamurthi Wirawan, I Gde Nengah Adhilaksman; Wangsa, Putu Gde Hari
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 7, Issue 2 (July 2024)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v7i2.102

Abstract

Background: Occupational contact dermatitis is a disease in the field of dermatology that arises in the work environment due to workers coming into direct contact with causative substances, be they irritants or allergens. Farmers are susceptible to various allergens or irritants when working in farming, clearing land, fertilizing, spraying, caring for, and during harvest. Epidemiological data showing contact dermatitis in Balinese farmers was still very minimal. So, based on the above background, we are interested in examining the characteristics of work-related contact dermatitis in farmers in Bali. Methods: This research method is descriptive research using a cross-sectional method that evaluates work-related contact dermatitis among farmers in Wongayo Gede Village, Penebel District, Tabanan Regency. Results: 56 farmers showed that 34 samples suffered from occupational contact dermatitis, of which 59% were men and 41% were women.  Based on the division of age groups according to WHO, it was found that youth (18-65 years) were 82%, middle-aged (66-79 years) 12%, and older adults (80-99) 6%. The highest educational background is elementary school 47%, high school 33%, and junior high school 15%. Conclusion: This research reveals that men's occupational contact dermatitis is more common. The most commonly found sample ages were young people in 18-65 years. Meanwhile, the most recent educational status of the sample was elementary school. The most common locations for skin lesions are on the upper and lower extremities.

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