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Jurnal Sains dan Kesehatan
Published by Universitas Mulawarman
ISSN : 23030267     EISSN : 24076082     DOI : 10.25026/jsk
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Jurnal Sains dan Kesehatan menerima naskah karya asli (Artikel Penelitian, Artikel Review, dan Studi Kasus), baik eksperimental maupun teoretis, dalam bidang-bidang berikut: Sains dan Kesehatan (Kedokteran, Farmasi, Kesehatan Masyarakat, Keperawatan, Kebidanan, Gizi, dan lain-lain). Tujuan penerbitan Jurnal Sains dan Kesehatan adalah untuk menyediakan informasi ilmiah tentang perkembangan ilmu dan teknologi di bidang Ilmu Pengetahuan dan Kesehatan.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 750 Documents
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Hubungan Tingkat Stres Kerja dengan Gangguan Somatoform pada Personel TNI Rindam Iskandar Muda Aceh Tahun 2023: The Relationship between Work Stress Levels and Somatoform Disorders in TNI Rindam Iskandar Muda Aceh Personnel in 2023 Alrasyid, Miko Dharma; Gunawan, Go Eddy; Permatasari, Nadia
Jurnal Sains dan Kesehatan Vol. 6 No. 5 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i5.2511

Abstract

Work-related stress is common and affects physical and mental well-being. The Indonesian National Armed Forces (TNI), crucial for regional security, face high stress levels due to various demands. Somatoform disorders, characterized by significant physical symptoms without clear medical causes, can result from this stress among TNI personnel.. This study aims to determine the relationship between the level of work-related stress and somatoform disorders among TNI personnel at Rindam Iskandar Muda Aceh in 2023. The research employs a quantitative approach using observational analytics with a cross-sectional study of 237 respondents, utilizing the OSI-R and PHQ-15 questionnaires. The results indicate that the distribution of work-related stress levels is predominantly mild, with 155 respondents (65.4%) falling into this category. The distribution of somatoform disorders is also predominant, with 125 respondents (52.7%) experiencing minimal somatoform disorders. Based on the Rank-Spearman correlation test, the two variables have a significant relationship with a positive correlation direction. Keywords:          work stress, somatoform disorders, TNI   Abstrak Stres kerja adalah fenomena umum di lingkungan kerja yang dapat memengaruhi kesejahteraan fisik dan mental. Tentara Nasional Indonesia (TNI) yang memiliki peran strategis dalam menjaga keamanan wilayah, rentan terhadap stres kerja tinggi karena berbagai tuntutan. Gangguan somatoform, yaitu kondisi psikologis dengan gejala fisik tanpa penyebab medis jelas, dapat terjadi pada personel TNI sebagai dampak dari stres kerja yang tinggi. Penelitian bertujuan untuk mengetahui hubungan antara tingkat stres kerja dengan gangguan somatoform pada personel TNI di Rindam Iskandar Muda Aceh tahun 2023. Penelitian menggunakan pendekatan kuantitatif dengan metode observasional analytics dengan studi cross-sectional terhadap 237 responden dengan menggunakan kuesioner OSI-R dan PHQ-15. Hasil penelitian menunjukkan distribusi tingkat stres kerja dominan sebanyak 155 responden (65,4%) dengan kategori tingkat stres kerja ringan dan distribusi gangguan somatoform dominan sebanyak 125 responden (52,7%) mengalami gangguan somatoform kategori minimal. Berdasarkan hasil uji korelasi Rank-Spearman, kedua variabel tersebut memiliki hubungan yang signifikan dengan arah korelasi positif. Kata Kunci:         stres kerja, gangguan somatoform, TNI
Front Cover, Editorial Information, Table of Content, Author Guideline, Back Cover Editor, Journal
Jurnal Sains dan Kesehatan Vol. 6 No. 4 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i4.2514

Abstract

Front Cover, Editorial Information, Table of Content, Author Guideline, Back Cover Editor, Journal
Jurnal Sains dan Kesehatan Vol. 6 No. 5 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i5.2515

Abstract

Formulasi Sediaan Gummy Candy dari Ekstrak Limbah Kulit Buah Rambutan (Nephelium Lappaceum L.) Kombinasi Madu sebagai Antioksidan: Formulation of Gummy Candy Rambutan Peel Extract (Nephelium Lappaceum L.) in Combination with Honey as Antioxidant Putri, Annisa; Ramadhan, Adam M.; Riki, Riki
Jurnal Sains dan Kesehatan Vol. 6 No. 6 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i6.2236

Abstract

Rambutan peel (Nephelium lappaceum L.) is an alternative feed with functional value that can be used as a preparation and contains secondary metabolite compounds, namely flavonoids, tannins, saponins and vitamin C which have the potential to be active substances. Its use as an antioxidant is combined with honey. The type of honey used is honey from forest bees that are widely cultivated, namely forest honey (Apis dorsata). The aim of this research is to create innovation in the form of a nutraceutical formula in the form of gummy candy as an antioxidant and other ingredients in one product and provide information that extracts from rambutan fruit skin waste and honey have many ingredients that are good for the body, for example antioxidants. This research is a laboratory research study and is supported by Design Expert V.13 software to obtain the optimal formula and uses a checklist instrument to obtain hedonic data. The test results showed that the formula had very strong antioxidant activity, namely 32.65 ppm with organoleptic test results having a sweet taste, slightly bitter taste, chewy texture, reddish brown color, lychee aroma, solid shape, water content 5.11% ± 0, 23, ash content 1.16% ± 0.47, pH 6.03 ± 0.06, and qualitatively no heavy metal contamination. The conclusion in this research is that the gummy candy preparation has very strong antioxidants, and meets the standard requirements for gummy candy. Keywords:          antioxidant, gummy candy, honey. Nephelium lappaceum L.   Abstrak Kulit rambutan (Nephelium lappaceum L.) merupakan salah satu pakan alternatif dengan nilai fungsional yang dapat dijadikan sediaan serta mengandung senyawa metabolit sekunder yaitu flavonoid, tanin, saponin, dan vitamin C yang berpotensi sebagai zat aktif. Pemanfaatannya sebagai antioksidan dikombinasi madu. Jenis madu yang digunakan madu dari lebah hutan yang banyak dibudidayakan yaitu madu hutan (Apis dorsata). Tujuan dari penelitian ini adalah untuk membuat inovasi berupa formula nutrasetika dalam bentuk gummy candy sebagai antioksidan dan memiliki kandungan lainnya dalam satu produk dan memberikan informasi bahwa ekstrak dari limbah kulit buah rambutan dan madu memiliki banyak kandungan yang baik untuk tubuh contohnya antioksidan. Penelitian ini merupakan penelitian riset laboratorium dan didukung dengan software Design Expert V.13 untuk mendapatkan formula yang optimal serta menggunakan instrumen isian checklist untuk mendapatkan data hedonik. Hasil pengujian diperoleh formula memiliki aktivitas antioksidan yang sangat kuat yaitu 32,65 ppm dengan hasil uji organoleptik memiliki rasa manis, sedikit meninggalkan rasa pahit, tekstur kenyal, warna coklat kemerahan, beraroma leci, berbentuk padat, kadar air 5,11%±0,23, kadar abu 1,16%±0,47, pH 6,03±0,06, dan tidak ada cemaran logam berat secara kualitatif. Kesimpulan dalam penelitian ini adalah sediaan gummy candy memiliki antioksidan yang sangat kuat, serta memenuhi standar persyaratan gummy candy. Kata Kunci:         antioksidan, gummy candy, madu,. Nephelium lappaceum L
Pharmaceutical Care for Smoking Cessation: A Pilot Study on Understanding Knowledge and Experience Through a Mixed-Methods Approach Lorensia, Amelia; Pratama, Anggara Martha; Wardani, Mariani Ika; Suryadinata, Rivan Virlando; Raharjo, Dian Natasya; Budipramana, Krisyanti
Jurnal Sains dan Kesehatan Vol. 6 No. 6 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i6.2249

Abstract

Smoking is one of the biggest threats to public health in the world, so pharmacists should have a role in a multidisciplinary team to provide pharmaceutical care in smoking cessation in pharmacy. The research purpose was to determine the level of knowledge and experience of pharmacist pharmacy services on smoking cessation programs at pharmacists in East Surabaya. This research was mixed-method research, using the explanatory sequential design strategy. Data collection was carried out from October 2021 to January 2022 in Surabaya, East Java, Indonesia. The research variable were knowledge and experience related to pharmaceutical care in smoking cessation. The sample were pharmacists who carried out clinical pharmacy services at pharmacies in East Surabaya. Respondents were interviewed in depth until the data reached the saturation level (saturation so that no new answers/explanations are found) in order to obtain good and usable qualitative data. This study involved 40 respondents. Most of the respondents had sufficient knowledge level (57.50%). Many participants attended seminars on smoking cessation (55%), but none of the respondents had experience in pharmaceutical services. Some respondents have experience in giving advice on smoking cessation to patients during drug delivery at pharmacies (62.50%). Most of the respondents knew dangers of smoking and its relation to health, but most of them cannot explain the theoretical mechanism of the disease pathophysiologically. Pharmacists in pharmacies had sufficient knowledge about smoking cessation, but the practice of pharmaceutical services was still lacking. This could be due to the need to improve information regarding smoking cessation regulations for health workers. Keywords:          experience, knowledge, pharmacist, smoking scessation
Efektivitas Ekstrak Etanol Daun dan Bunga Paitan [Tithonia diversifolia (Hemsley) A. Gray] terhadap Mortalitas Larva Nyamuk Aedes aegypti L.: Effectiveness of Ethanol Extract of Paitan Leaves and Flowers [Tithonia diversifolia (Hemsley) A. Gray] on Mortality of Aedes aegypti L. Mosquito Larvae Garini, Aselia Chandra Arda; Rahayu, Sofia Ery; Masita, Rahmi
Jurnal Sains dan Kesehatan Vol. 7 No. 1 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i1.2266

Abstract

Dengue Hemorrhagic Fever (DHF) is a disease caused by the Dengue virus and transmitted through the bite of Ae. aegypti mosquitoes. One effort to eradicate Ae. aegypti mosquito larvae involves the use of chemical larvicides, but this leads to residues and poses risks to non-target organisms. Leaves and flowers of [Tithonia diversifolia (Hemsley) A. Gray] contain secondary metabolites toxic to larvae. This study aims to determine the content of secondary metabolites, the effectiveness of various concentrations of leaf and flower extracts of Tithonia diversifolia on the mortality of Ae. aegypti mosquito larvae, and to identify the effective concentration (LC50). Leaves and flowers are mixed in a 1:1 ratio and macerated using 96% ethanol. Concentrations used are 0, 500, 1000, 1500, 2000 ppm, with positive controls repeated 4 times. Larval mortality is observed every 24, 48, 72, and 96 hours. The results show that leaf and flower extracts contain alkaloids, saponins, tannins, and flavonoids. There is a significant effect among concentrations on the mortality of Ae. aegypti larvae, with higher concentrations resulting in increased mortality. The effective concentration (LC50) of leaf and flower extracts is 1204,899 ppm after 96 hours of observation, indicating their potential as natural larvicides. Keywords:          Larvicides, Aedes aegypti, Tithonia diversifolia (Hemsley) A. Gray   Abstrak Penyakit Demam Berdarah Dengue (DBD) adalah penyakit yang disebabkan oleh virus Dengue dan ditularkan melalui gigitan nyamuk Ae. aegypti. Salah satu upaya yang dilakukan untuk memberantas jentik nyamuk Ae. aegypti. adalah penggunaan larvasida kimia, namun menyebabkan residu dan berbahaya bagi organisme non target. Daun dan bunga paitan [Tithonia diversifolia (Hemsley) A. Gray] mengandung senyawa metabolit sekunder yang bersifat toksik bagi larva. Tujuan penelitian ini untuk mengetahui kandungan senyawa metabolit sekunder, efektivitas berbagai konsentrasi ekstrak daun dan bunga paitan terhadap mortalitas larva nyamuk Ae. Aegypti. dan mengetahui konsentrasi efektif (LC50). Daun dan bunga paitan dicampur dengan perbandingan 1:1 dan dimaserasi menggunakan etanol 96%. Konsentrasi yang digunakan adalah 0, 500, 1000, 1500, 2000 ppm, dan kontrol positif dengan pengulangan 4 kali. Pengamatan mortalitas larva dilakukan setiap 24, 48, 72, dan 96 jam. Hasil penelitian menunjukkan bahwa ekstrak daun dan bunga paitan mengandung senyawa alkaloid, saponin, tanin, dan flavonoid. Terdapat pengaruh nyata antar konsentrasi terhadap mortalitas larva Ae. Aegypti.  Semakin tinggi konsentrasi ekstrak maka semakin tinggi mortalitas larva. Konsentrasi efektif (LC50) ekstrak daun dan bunga paitan adalah sebesar 1204,899 ppm di 96 jam pengamatan. Hal ini menunjukkan bahwa ekstrak daun dan bunga paitan dapat dikembangkan sebagai larvasida alami. Kata Kunci:         Larvasida, Aedes aegypti L., Tithonia diversifolia (Hemsley) A. Gray
Pengetahuan dan Persepsi Masyarakat terhadap Penyakit Tuberkulosis di Pedurungan Tengah Kota Semarang: Knowledge and Perception of Tuberculosis in Pedurungan Sub-district, Semarang City Afriansya, Roni; Hadipranoto, Ichsan; Sofyanita, Eko Naning; Duri, Iin Demiany; Nabila, Jihan
Jurnal Sains dan Kesehatan Vol. 6 No. 6 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i6.2285

Abstract

The global commitment to end Tuberculosis is outlined in the End TB Strategy, which targets reducing the incidence of Tuberculosis by 80% and deaths from Tuberculosis by up to 90% by 2030. To support the elimination of TBC, Indonesia has created six strategies. One is Optimization effort promotion and prevention, treating tuberculosis prevention and controlling infection. Level of knowledge and perception are essential in the control of TBC disease. Conscious society of the danger of TBC disease will be beneficial to the success of the eradication program TBC disease. Purpose: to determine the level of public knowledge and perception about TBC disease in Pedurungan Sub-district, Semarang City. Methods: This research uses a quantitative descriptive research type with a cross-sectional time approach. The sample in this study were residents of Pedurungan District, Semarang City. Data collection was carried out directly on research subjects using questionnaires and interviews. Result: The knowledge level research results showed that most respondents (62.4%) had sufficient knowledge about TBC disease. The research result category perception gets 88.7% to have a positive perception of TBC disease. Conclusion: the people of Pedurungan Tengah have sufficient knowledge and categories of perception classified as good. Keywords:          Tuberculosis, Knowledge, Perception   Abstrak Komitmen global dalam mengakhiri tuberkulosis dituangkan dalam End TB Strategy yang menargetkan penurunan insidensi tuberkulosis 80% dan kematian akibat tuberkulosis hingga 90% pada tahun 2030. Upaya dalam mendukung eliminasi TBC, Indonesia telah membuat enam strategi. Salah satunya adalah Optimalisasi upaya promosi dan pencegahan, pemberian pengobatan pencegahan tuberculosis serta pengendalian infeksi. Tingkat pengetahuan dan persepsi berperan penting dalam pengendalian penyakit TBC. Masyarakat yang sadar akan bahaya penyakit TB akan sangat membantu dalam keberhasilan program pemberantasan penyakit TBC. Penelitian ini menggunakan jenis penelitian deskriptif kuantitatif dengan pendekatan waktu cross sectional. Sampel pada penelitian ini adalah warga Kecamatan Pedurungan Kota Semarang. Pengambilan data di lakukan secara langsung pada subjek penelitian dengan menggunakan kuesioner dan wawancara. Hasil penelitian tingkat pengetahuan mendapatkan sebagian besar responden (62,4%) memiliki pengetahuan yang cukup tentang penyakit TBC. Hasil penelitian kategori persepsi mendapatkan 88,7% memiliki persepsi positif terhadap penyakit TBC. Dan dapat disimpulkan bahwa masyarakat kelurahan Pedurungan Tengah memiliki tingkat pengetahuan yang cukup dan kategori persepsi tergo-long baik. Kata Kunci:         Tuberkulosis, Pengetahuan, Persepsi
Identifikasi Drug Related Promblems (DRPs) Kategori Reaksi Obat Merugikan pada Pasien Penderita Hipertensi di Puskesmas X, Kabupaten Pangkep, Sulawesi Selatan: Identification of Drug Related Problems (DRPs) Category of Adverse Drug Reactions in Patients with Hypertension at X Health Center, Pangkep Regency, South Sulawesi Yunus, Arifuddin; Hashary, A. Rufaidah; Fajriani, Asruri
Jurnal Sains dan Kesehatan Vol. 6 No. 6 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i6.2290

Abstract

Hypertension is a disease of increased systolic (>140 mmHg) and diastolic (>90 mmHg) blood pressure and is influenced by age, gender, genetics, diet, smoking and stress. Drug Related Problems (DRPs) are unexpected events in the therapeutic process and affect treatment, therefore the identification of DRPs can improve the effectiveness of treatment. This study aims to determine the incidence of DRPs in the category of adverse drug reactions in hypertensive patients at the X Health Center, Pangkep Regency. This study is a non-experimental study and the data were taken retrospectively. The population in this study were all hypertension patients from August to October 2022. Samples were taken by purposive sampling method according to the inclusion criteria. From this study, 63 patients (80.76%) had potential drug interactions out of 78 patients. Keywords:          Hypertension, Drug Related Problems (DRPs), Drug Interactions   Abstrak Hipertensi adalah penyakit peningkatan tekanan darah sistolik (>140 mmHg) dan diastolik (> 90 mmHg) dan dipengaruhi oleh faktor usia, jenis kelamin, genetika, pola makan, merokok dan stress. Drug Related Problems (DRPs) adalah kejadian tidak terduga pada proses terapi dan mempengaruhi pengobatan oleh karena itu identifikasi DRPs dapat meningkatkan efektivitas pengobatan. Penelitian ini bertujuan mengetahui kejadian DRPs kategori reaksi obat merugikan pada pasien hipertensi di Puskesmas X Kabupaten Pangkep. Penelitian ini merupakan penelitian noneksperimental dan data diambil secara retrospektif. Populasi dalam penelitian ini adalah semua pasien hipertensi bulan Agustus – Oktober 2022. Sampel diambil dengan metode purposif sampling sesuai kriteria inklusi. Dari penelitian ini diperoleh hasil 63 pasien (80,76%) terdapat potensi interaksi obat dari 78 pasien. Kata Kunci:         Hipertensi, Drug Related Problems (DRPs), Interaksi Obat
Efektivitas Rebusan Jahe Putih Kecil (Zingiber officinale var. Amarum) Terhadap Gambaran Histologi Pankreas Mencit (Mus Musculus) Diabetes Melitus: Effectivity of Small White Jahe (Zingiber officinale Var. Amarum) Decocolation on Histological Discussion of Heart of Mencites (Mus Musculus) Diabetes Mellitus Kodariah, Liah; Aulia, Syifa; Fadillah, Wasiyah Khusna; Rahayu, Amalia
Jurnal Sains dan Kesehatan Vol. 6 No. 6 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i6.2336

Abstract

Diabetes is a chronic form of metabolic disorder characterized by an increase in blood sugar levels above the normal limit or called hyperglycemia. This hyperglycemia condition causes pancreatic beta cells to produce Reactive Oxygen Species (ROS). Ginger contains a variety of secondary metabolites and active phenolic compounds, such as flavonoids, gingerol and shogaol as a treatment for diabetes that has the potential to reduce blood sugar levels and improve the histology of the pancreas of mice. The purpose of this study was to determine the picture of pancreatic histology of mice (Mus musculus) induced by alloxan after being given small white ginger (Zingiber officinale var. Amarum). This study used experimental research using a complete randomized design method in mice consisting of 5 groups. The groups in this study consisted of negative control group, positive control group, comparison control group, dose I treatment group, and dose II. Pancreatic histology of mice (Mus musculus) was made with Hematoxylin Eosin (HE) staining. The results showed that dose I was more effective than dose II to reduce glucose and histology improvement in alloxan-induced pancreas. Keywords:          Diabetes, Small White Ginger, Pancreas   Abstrak Diabetes adalah bentuk gangguan metabolisme kronis yang ditandai dengan peningkatan kadar gula dalam darah di atas batas normal atau disebut hiperglikemia. Kondisi hiperglikemia ini menyebabkan sel beta pankreas memproduksi Reactive Oxygen Species (ROS). Jahe mengandung berbagai macam senyawa metabolit sekunder dan fenolik aktif, seperti flavonoid, gingerol dan shogaol sebagai pengobatan penyakit diabetes yang berpotensi menurunkan kadar gula darah dan memperbaiki gambaran histologi pankreas mencit. Tujuan penelitian untuk mengetahui gambaran histologi pankreas mencit (Mus musculus) yang diinduksi aloksan setelah diberi air rebusan jahe putih kecil (Zingiber officinale var. Amarum). Penelitian ini menggunakan penelitian eksperimental metode rancangan acak lengkap pada mencit yang terdiri dari 5 kelompok. Kelompok dalam penelitian ini terdiri dari kelompok kontrol negatif, kelompok kontrol positif, kelompok kontrol pembanding, kelompok perlakuan dosis I, dan dosis II. Histologi pankreas mencit (Mus musculus) dibuat dengan pewarnaan Hematoxylin Eosin (HE). Hasil penelitian menunjukkan bahwa dosis I lebih efektif daripada dosis II untuk menurunkan glukosa darah dan perbaikan histologi pada pankreas yang diinduksi aloksan. Kata Kunci:         Diabetes, Jahe Putih Kecil, Pankreas
Formulasi Body Scrub Beras Merah (Oryza nivara) dan Madu (Mel depuratum) sebagai Pengangkat Sel Kulit Mati: A Body-Cleaning Plan of Red Rice (Oryza nivara) and Honey (Mel depuratum) to Eliminate Dead Skin Cells Ani, Nur; Paulitan, Alsih Priskila Gani
Jurnal Sains dan Kesehatan Vol. 6 No. 6 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i6.2356

Abstract

Earthy-colored rice contains flavonoids, which have the capability of being cancer prevention agents that help kill and settle free revolutionaries. In the interim, honey can be utilized as a humectant and prevent dry skin. This exploration means figuring out how to make a body-clean plan from red rice (Oryza nivara.) and honey (Mel depuratum) to eliminate dead skin cells with shifting fixations, to be specific, 4.5%, 6.5%, and 8.5%. This exploration utilizes subjective techniques, and the consequences of the examination are that red rice and honey can be figured out in body scour arrangements with differing groupings of 4.5%, 6.5%, and 8.5%, and details of red rice (Oryza nivara) and honey (Mel depuratum) show that 3 definitions with convergences of 4.5%, 6.5%, and 8.5% have great actual quality tests and meet the necessities. Keywords:          plan, body scour, earthy-colored rice, honey, dead skin cells   Abstrak Beras merah mengandung flavonoid yang berfungsi sebagai antioksidan yang membantu menetralkan dan menstabilkan radikal bebas. Sedangkan madu dapat digunakan sebagai humektan dan mencegah kulit kering. Penelitian ini bertujuan untuk mengetahui cara pembuatan formulasi sediaan body scrub beras merah (Oryza nivara.) dan madu (Mel depuratum) sebagai pengangkat sel – sel kulit mati dengan variasi konsentrasi yaitu 4,5 %, 6,5 % dan 8,5 %. Penelitian ini menggunakan metode kualitatif dan hasil penelitian yaitu Beras merah dan madu dapat diformulasikan dalam sediaan body scrub dengan variasi konsentrasi 4,5%, 6,5% dan 8,5% dan Formulasi sediaan beras merah (Oryza nivara) dan madu (Mel depuratum) menunjukkan bahwa 3 formulasi dengan konsentrasi 4,5%, 6,5% dan 8,5% memiliki uji mutu fisik sediaan yang baik dan memenuhi syarat. Kata Kunci:         formulasi, body scrub, beras merah, madu, sel-sel kulit mati

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