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Jurnal Info Kesehatan
Published by Poltekkes Kemenkes Kupang
ISSN : 0216504X     EISSN : 2620536X     DOI : https://doi.org/10.31965/infokes
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology
Jurnal Info Kesehatan with registered number ISSN 0216-504X (Print), 2620-536X (Online) is a scientific journal which managed by the Research and Community Service Unit, Politeknik Kesehatan Kemenkes Kupang in cooperation with Indonesian Oral Health and Therapists Association with the MoU. The journal is registered in the CrossRef system with Digital Object Identifier (DOI) prefix 10.31965. This journal focuses on the publication of the results of scientific research related to the field of health. The published article originated from internal and external academicians Politeknik Kesehatan Kemenkes Kupang. This journal is published by the Research and Community Service Unit, Politeknik Kesehatan Kemenkes Kupang, Indonesia. Jurnal Info Kesehatan is a periodical issue that contains research articles or research results equivalent to the results of research and thought results in the field of health, is original and has never been published before. Jurnal Info Kesehatan is expected to be a medium for delivering scientific findings and innovations in the fields of medicine, nursing, pharmacology, toxicology, pharmaceutics, public health services engaged in the field of hospital services and health center, as well as health practitioners and other institutions. Jurnal Info Kesehatan is published 4 times a year (March, June, September and December). Jurnal Info Kesehatan is a peer-reviewed journal and open-access journal focusing on health sciences. This focus includes areas and scope related to aspects of medicine, nursing, pharmacology, toxicology, pharmaceutics, and public health services. Every article that goes to the editorial staff will be selected through Initial Review processes by the Editorial Board. Then, the articles will be sent to the peer reviewer and will go to the next selection by the Double-Blind Review Process. After that, the articles will be returned to the authors for revision. These processes take four months for a maximum time. In each manuscript, peer reviewers will be rated from the substantial and technical aspects. The final decision of articles acceptance will be made by the Editors according to the Reviewer comments. Peer reviewer who collaborated with Jurnal Info Kesehatan is an expert in the health area and issues around it.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 477 Documents
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Treatment Duration and Its Impact on the Number of Polymorphonuclear, Mononuclear and Neutrophil Lymphocyte Ratio as Indicators of Recovery Rate in Tuberculosis Patients Aini, Aini; Fihiruddin, Fihiruddin; Diarti, Maruni Wiwin; Tatontos, Erlin Yustin; Salleh, Mohd Nazil
JURNAL INFO KESEHATAN Vol 23 No 4 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss4.1960

Abstract

The calculation of leukocyte types can be used to assess the level of infection or inflammation, particularly through the neutrophil-lymphocyte ratio (NLR). The NLR has been established as a useful biomarker for predicting bacteremia. Although differential leukocyte count and the neutrophil–lymphocyte ratio (NLR) have been widely proposed as indicators of infection and inflammation, their clinical interpretation remains unclear across disease states, particularly in tuberculosis. Current evidence is limited regarding how leukocyte profiles and NLR change during standard anti tuberculosis treatment (ATT), especially in the early and intermediate phases of therapy. Furthermore, it is not well established whether changes in leukocyte subtypes reflect treatment response or disease recovery in tuberculosis patients. Therefore, there is a need to quantify changes in leukocytes and NLR during TB treatment and to determine their potential role as readily accessible biomarkers for monitoring therapy outcomes. The goal of this study was to determine the effect of treatment duration on the number of polymorphonuclear cells, mononuclear cells, and the neutrophil-lymphocyte ratio as indicators of recovery in TB patients. This study employed a cross-sectional design with an analytical observational approach, involving 26 TB patients undergoing treatment for 1 to 6 months. The results showed the following average cell counts (per microliter) over the treatment period: basophils at 0.04, eosinophils at 0.30, neutrophils at 4.10, lymphocytes at 2.36, monocytes at 1.84, and a neutrophil-lymphocyte ratio of 0.53. One-way ANOVA analysis revealed a positive correlation between basophils, neutrophils, lymphocytes, monocytes, and the neutrophil-lymphocyte ratio with TB recovery. In conclusion, treatment of TB patients during the fourth to sixth month, or in the advanced phase of treatment showed differences in the number of  polymorphonuclear cells, mononuclear cells and  the NLR ratio compared to intensive phase treatment in TB patients at the Karang Taliwang and akranegara Health Centers.
An Experimental Study: Aloe vera Extract Mouthwash against Dental Plaque Husna, Amakhul; Herlina, Rita; Femala, Dian; Nadia, Hima Mahda; Azkiya, Hilda
JURNAL INFO KESEHATAN Vol 23 No 4 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss4.1978

Abstract

Recent studies have demonstrated the potential of Aloe vera as a natural agent in dental care based on in vivo and in vitro evidence; however, research evaluating its effectiveness as a mouthwash remains limited. This study aimed to assess the efficacy of Aloe vera mouthwash in reducing dental plaque among school-aged children in Indonesia. A structured experimental study with a pretest–posttest design was conducted involving 45 children aged 10–12 years in West Kalimantan. Dental plaque levels were measured using the Personal Hygiene Performance (PHP) Index before and after the intervention. The results showed that the mean dental plaque score decreased from 2.76 at baseline to 1.75 after the use of Aloe vera mouthwash. Statistical analysis using a paired t-test indicated a significant reduction in dental plaque scores following the intervention. In conclusion, Aloe vera mouthwash is effective in reducing dental plaque among children and may serve as a potential alternative preventive agent for periodontal disease.
The Effect of Self-Resignation Exercise on the Quality of Life of HIV Patients Nurhayatun, Evi; Agung, Ratih Arianita; Wijaya, Hanifan Danu; Hanif, Muhammad Ifham; Harioputro, Dhani Redhono
JURNAL INFO KESEHATAN Vol 23 No 4 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss4.1994

Abstract

People living with HIV/AIDS (PLWHA) are vulnerable to anxiety related to their illness, which can adversely affect inflammatory markers such as the Neutrophil-to-Lymphocyte Ratio (NLR) and overall quality of life (QOL). This study aimed to examine the effect of Self-Resignation Exercise as a complementary and holistic intervention on NLR and quality of life among HIV patients experiencing anxiety disorders. A randomized controlled trial with a pretest–posttest control group design was conducted in the Infection Subsection of Dr. Moewardi Hospital, Surakarta, starting in January 2024. Participants were HIV patients with anxiety disorders who had stable physical conditions and received routine treatment, and they were randomly assigned to a control group (n = 20) and an intervention group (n = 20). Anxiety levels were assessed using the Hamilton Rating Scale for Anxiety (HRSA), quality of life was measured with the WHOQOL-BREF, and inflammatory status was evaluated through blood tests to determine NLR. The intervention group received Self-Resignation Exercise in addition to standard care, while the control group received standard care alone. The results demonstrated a significant reduction in anxiety levels and a significant improvement in quality of life in the intervention group compared to the control group, with all measured outcomes showing p-values < 0.001. In conclusion, Self-Resignation Exercise is effective in reducing anxiety and improving quality of life in people living with HIV/AIDS, indicating its potential as a complementary approach to enhance both psychological well-being and overall health status.
The Effects of Screen Time on Early Childhood Development: A Systematic Literature Review Lumban Gaol, Riama Claudia Christine; Fajar, Nur Alam
JURNAL INFO KESEHATAN Vol 23 No 4 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss4.2009

Abstract

The effects of screen time on young children warrant greater attention, particularly as screen use has increased during the COVID-19 pandemic. Excessive screen exposure in early childhood reduces opportunities for adequate stimulation and limits children’s engagement with their physical and social environments. When children do not receive sufficient developmental stimulation during this critical period, optimal brain development may be affected, potentially leading to delays or disorders across various developmental domains. This review aimed to further examine the negative impact of screen time on early childhood development. Guided by the PRISMA guidelines, a comprehensive search was conducted across Google Scholar, PubMed, and Scopus using the keywords “screen time” and “child development” for articles published between 2021 and 2025. A total of 15 studies met the eligibility criteria. The findings consistently show that excessive screen time negatively affects several aspects of early childhood development, including motor, speech-language, cognitive, and social-emotional domains. The review also underscores the critical role of parents in regulating children’s screen use to mitigate these risks. In conclusion, excessive screen media exposure diminishes developmental stimulation and increases the likelihood of developmental delays; therefore, active parental involvement in managing screen time is essential to promote healthy child development.
A Case-Control Study of Environmental Risk Factors for Pulmonary Tuberculosis: Housing Density, Indoor Humidity, and Smoking Habits Rahmatullah, Ilham; Akbar , Sulung Alfianto; Susilawati, Rosi
JURNAL INFO KESEHATAN Vol 23 No 4 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss4.2069

Abstract

Pulmonary tuberculosis (TB) remains a major public health problem in urban settings and is strongly influenced by environmental and behavioral factors. This study aimed to examine the effects of housing density, indoor humidity, and smoking behavior on the incidence of pulmonary TB in the working area of the Segiri Health Center, Samarinda. An observational analytic study with a case–control design was conducted involving 50 respondents, consisting of 25 TB cases and 25 matched controls. Data were collected through structured interviews, direct observation, and environmental measurements, and were analyzed using chi-square tests and odds ratios. The results indicated that high housing density was significantly associated with an increased risk of TB (OR = 11.16; p = 0.001), while smoking behavior was also significantly related to TB incidence (OR = 5.63; p = 0.010). High indoor humidity showed an increased risk but was not statistically significant. In addition, a large proportion of TB cases were frequently exposed to secondhand smoke in enclosed spaces. In conclusion, high housing density and smoking, including exposure to secondhand smoke, are key determinants of pulmonary TB incidence, whereas indoor humidity demonstrated a weaker association. These findings highlight the importance of improving housing conditions and strengthening tobacco control efforts as part of TB prevention strategies in urban areas.
Exploration of Non-Pharmacological Interventions in Reducing Patient Anxiety in the Operating Room: A Scoping Review Maulana, Indra; Platini, Hesti; Fadila, Salsabila Sakhi
JURNAL INFO KESEHATAN Vol 23 No 4 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss4.2136

Abstract

Preoperative anxiety is a common problem that impacts surgical outcomes and patient well-being. Non-pharmacological interventions offer a safe alternative to managing anxiety without the side effects of medication. This scoping review aims to map the evidence related to non-pharmacological interventions in reducing patient anxiety in the operating room. Following the Arksey and O’Malley framework and the JBI guidelines, a search was conducted in databases such as PubMed and Scopus until August 2025, with inclusion criteria of primary and secondary studies on non-pharmacological interventions in preoperative patients. Data were extracted for variables such as intervention type, population, and effectiveness, and analyzed narratively and thematically. Of the 15 studies, interventions such as music therapy, virtual reality, clown therapy, aromatherapy, and pre-operative education were effective in reducing anxiety by 15-30% in children and adults, with additional benefits on patient satisfaction and physiological stability. Interactive interventions were more effective in children, while sensory therapy was superior in adults. Non-pharmacological interventions are a promising strategy for pre-operative anxiety management, with the need for further research in elderly and emergency surgery populations to strengthen clinical applications.       
Hypertension and Salt Consumption: A Story from A Coastal Area Respati, Titik; Fadia, Zulfi Noor; Purbaningsih, Wida; Yulianto, Fajar A; Wahyuni, Tri
JURNAL INFO KESEHATAN Vol 23 No 4 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss4.2147

Abstract

Indonesia has a high prevalence of hypertension accompanied by relatively high salt consumption, posing a significant public health concern, particularly in coastal areas where salty foods and saline water are commonly available. This study aimed to analyze the relationship between salt consumption and hypertension grade among residents in a coastal area. A cross-sectional study was conducted involving 174 hypertensive patients in Pangandaran District who had recorded blood pressure measurements at the local health center. Data on respondents’ characteristics, including age, sex, education level, occupation, and income, were collected. Salt intake was assessed using a Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ). Multiple logistic regression analysis was performed to examine the association between salt consumption and hypertension grade while controlling for potential confounding variables. The mean sodium intake among respondents was 1312.11 ± 596.27 mg/day. Salt consumption was significantly associated with hypertension grade (β = 0.001; p = 0.004) after adjustment for education level and type of occupation. In conclusion, higher salt consumption is significantly associated with increased severity of hypertension in coastal populations, highlighting the need for targeted dietary interventions to reduce salt intake in these areas.
Socio Demographic Factors Related to Father Presence in Parenting Adolescents Pusparatri, Edita; Rahmawati, Ashri Maulida; Khoirunnisa, Fania Nurul; Jauhar, Muhamad; Siwitri, Gandi; Febryanto, Dwi
JURNAL INFO KESEHATAN Vol 23 No 4 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss4.2165

Abstract

Father presence plays a crucial role in the emotional and psychological development of adolescents, yet various socio-demographic factors remain barriers to understanding the significance of fathers' role in parenting. Adolescents who grow up without their fathers are more vulnerable to mental health and social problems, which in turn impact their self-esteem and academic achievement. This study aimed to identify the strongest socio-demographic factors associated with the presence of fathers in the care of adolescents in Kudus District. This study used an observational analytic design with a cross-sectional approach, which was analyzed through the chi-square test and binary logistic regression. The sample consisted of 332 purposively selected high school students. Independent variables included gender difference with the child, parents' marital status, father's education, father's occupation, economic status and family function, while the dependent variable was the level of father’s presence in parenting. The results of the analysis showed that family function in parenting is the strongest social factor that positively influences father presence in adolescent parenting (OR = 6.651, p < 0.05). In addition, the demographic factor of marital status also positively influenced father’s presence in adolescent care (OR = 2.447, p < 0.05). Meanwhile, gender differences between father and child, father's education level, father's occupation, and economic status did not have a significant correlation. The study conclusion emphasizes the importance of integrating family functions in an effort to increase father's participation in parenting, as well as the implications for practice of community health workers, family health programs, and school based family programs.
Dietary Patterns as Determinants of Ferritin Status in Adolescent Girls Octavia, Tera; Margawati, Ani; Limijadi, Edward Kurnia Setiawan
JURNAL INFO KESEHATAN Vol 23 No 4 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss4.2167

Abstract

Iron deficiency, commonly indicated by low ferritin concentrations, remains a major nutritional problem among adolescent girls and poses risks to growth, cognitive development, and long-term health. While previous studies have largely focused on single nutrients or iron intake, evidence on the relationship between overall dietary patterns and ferritin status among Indonesian adolescents is limited. This study aimed to examine the association between dietary patterns and ferritin status among adolescent girls in Pekalongan, Indonesia. A cross-sectional study was conducted among 80 adolescent girls aged 15–19 years. Serum ferritin levels were measured using ELISA, and dietary patterns were derived using pattern-based dietary assessment. Age, nutrition knowledge, body mass index, physical activity, and hemoglobin concentration were also examined as potential correlates. Dietary pattern was significantly associated with ferritin status, with poorer dietary patterns linked to lower ferritin concentrations. In contrast, no significant associations were observed for body mass index, physical activity, hemoglobin levels, or other individual characteristics, suggesting that overall dietary quality may play a more prominent role in iron stores than single anthropometric or behavioral factors. Given the cross-sectional design and modest sample size, causal inference and generalizability are limited. Nevertheless, the findings highlight the potential value of improving dietary quality through adolescent-focused nutrition education and school-based nutrition strategies to support iron status and reduce the risk of iron deficiency in this population.
Phytochemical Compounds of Ethanol Extract Kigelia africana (Lam.) Benth. from Pericarpium, Fructus, and Semen using LCMS/MS and in Silico Study (Potential of Phosphodiesterase-5 Inhibitor) Samudra, Rizka Putra; Sukardiman, Sukardiman; Widyowati, Retno
JURNAL INFO KESEHATAN Vol 23 No 4 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss4.2261

Abstract

Erectile dysfunction can be treated by pharmacological therapy with phosphodiesterase-5 inhibitors (PDE5-I). One plant that has a function as a phosphodiesterase-5 inhibitor is Kigelia africana (Lam.) Benth. Research on Kigelia africana (Lam.) Benth. An extract as a Phosphodiesterase type 5 (PDE 5) inhibitor is still lacking. This research aims to determine the phytochemical compounds in the 70% ethanol extract of the pericarpium, fructus and semen of Kigelia africana (Lam.) Benth. with LC-MS/MS and to determine the ligand-protein interaction through in-silico studies. In previous studies, no one compared each part of the Kigelia africana (Lam.) Benth. as an aphrodisiac. The results of the identification of the 70% ethanol extract of Kigelia africana (Lam.) Benth. found several alkaloids, flavonoids, iridoids, phenolics, polyphenols, coumarins, steroids and fatty acids. Based on the results of molecular docking on 70% ethanol extract of pericarpium, fructus and semen of Kigelia africana (Lam.) Benth., 18 compounds, 20 compounds and 18 compounds were obtained sequentially, which were analyzed using LC-MS/MS. The sitosterol compound with (∆G = -8.90 kcal/mol) was identified in the three parts of the 70% ethanol extract sample of kunto bimo fruit, which showed the highest affinity for binding to the target protein compared to sildenafil with (∆G = -8.68 kcal/mol). Sitosterol compound has the same amino acid residues as the native ligand, namely ILE A:824, TYR A:664, ALA A:779, ILE A:768, ALA A:767, LEU A:765, ASN A:661, HIS A:613, PHE A:786, VAL A:782, LEU A:804, MET A:816, PHE A:820 in hydrophobic bonds. Phytochemical compounds from Kigelia africana (Lam.) Benth. It has the potential as an alternative additional therapy and a promising source for the discovery of new drugs as aphrodisiacs targeting PDE5.

Page 47 of 48 | Total Record : 477

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