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Health Science & Biomedical Journal (HSBJ)
Published by PT. Literasi Indonesia Emas
ISSN : 30907543     EISSN : 30907535     DOI : -
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing
Health Science & Biomedical Journal (HSBJ) is a peer-reviewed scientific journal that publishes original research articles, reviews, and short communications in the fields of health science and biomedical science. The journal aims to be a platform for the dissemination of high-quality scientific knowledge that contributes to the advancement of health and medical technologies. We welcome contributions from researchers, academics, and practitioners in the following fields: Biomedical Science – including molecular biology, immunology, pathology, and laboratory diagnostics; Nursing – including clinical nursing, community nursing, nursing education, and nursing management; Midwifery – covering maternal and child health, reproductive health, and midwifery care practices; Pharmacy – including pharmacology, pharmaceutical sciences, drug development, and clinical pharmacy; Medical Laboratory Technology – including hematology, microbiology, clinical chemistry, and histopathology. The journal accepts both field-based and literature-based research that promotes innovation, evidence-based practice, and interdisciplinary collaboration in health and biomedical sciences
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 11 Documents
 1   2 
The Effectiveness Of Patchouli Leaf Decoction (Pogostemon cablin Benth) as a Bioinsecticide Against Aedes sp Wenty, Darmayanita; Hardiansyah, Ikdal; Sultanul Aulya, Muhammad; Idris, Sri Aprilianti; Firdayanti; Susanti, Susanti
HEALTH SCIENCE & BIOMEDICAL JOURNAL Vol. 1 No. 1 (2025): April 2025 : Health Science & Biomedical Journal (HSBJ)
Publisher : Literasi Indonesia Emas (PT)

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Abstract

Background: Aedes sp. is a primary vector responsible for transmitting several diseases such as dengue hemorrhagic fever, filariasis, chikungunya, leptospirosis, and bubonic plague. The expansion of its population from urban to rural areas necessitates new control measures. Patchouli leaves (Pogostemon cablin Benth) contain bioactive compounds such as flavonoids, tannins, and phenolic hydroquinone with potential mosquito-killing properties. Objective: To determine the effectiveness of boiled water extract of patchouli (Pogostemon cablin Benth) leaves against the mortality of Aedes sp. mosquitoes. Methods: An experimental design was used with three treatment groups receiving patchouli leaf extract concentrations of 80%, 90%, and 100%, along with a negative control (aquadest) and a positive control. Each treatment involved 25 mosquitoes with three replications. Observations were made over a 24 hour period (1440 minutes). Data were analyzed using a one-way ANOVA test. Results: The average mosquito mortality was 6.6 mosquitoes (27%) at 80% concentration, 11.6 mosquitoes (48%) at 90% concentration, and 16 mosquitoes (64%) at 100% concentration. Conclusion: The boiled water extract of patchouli leaves (Pogostemon cablin Benth) demonstrated effectiveness in increasing Aedes sp. mortality, with higher concentrations showing greater mosquito-killing activity.
The Relationship of Parity, Age And Fetal Weight Interpretation With A Rip of The Road of Birth in A Mom In Membership in Beteleme Puskesmas Morowali Regency Rizkiyati, Ita; Dhanio, Yeyen Wulandari
HEALTH SCIENCE & BIOMEDICAL JOURNAL Vol. 1 No. 1 (2025): April 2025 : Health Science & Biomedical Journal (HSBJ)
Publisher : Literasi Indonesia Emas (PT)

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Introduction: In developing countries, the main causes of maternal death are direct obstetric factors, namely postpartum hemorrhage, infection, and eclampsia. Perineal rupture can lead to postpartum hemorrhage. Objective: The aim of this study was to determine the causes of birth canal tears during childbirth at the Beteleme Health Center. Method: This descriptive study employed a cross-sectional approach. The sample consisted of 30 mothers who experienced birth canal tears, selected using a total sampling technique. Data were collected using observation sheets, and the Chi-Square statistical test was used for analysis with a significance level of α = 0.05. Results: Of the 30 respondents, the majority (80%) were in the age group of 20–33 years. Most of the respondents (83.3%) were primiparous (first-time mothers). Regarding fetal weight, 25 mothers (83.3%) delivered babies weighing less than 3800g, while 5 mothers (16.7%) delivered babies weighing over 3800g. Statistical analysis revealed that the Sig value for the age category was > 0.05, indicating no significant relationship between age and birth canal tears. However, the Sig values for parity and fetal weight were < 0.05, indicating a significant relationship between these factors and the incidence of birth canal tears. Conclusion: This study concluded that there is no relationship between age and the incidence of birth canal tears, but there is a significant relationship between parity and fetal weight with the incidence of birth canal tears in mothers giving birth at the Beteleme Health Center.
The Effect of Education on Knowledge of Sexually Transmitted Infections in Women of Reproductive Age at Lee Health Center, North Morowali Regency Mutmaina; Sakulat, Gabriella
HEALTH SCIENCE & BIOMEDICAL JOURNAL Vol. 1 No. 1 (2025): April 2025 : Health Science & Biomedical Journal (HSBJ)
Publisher : Literasi Indonesia Emas (PT)

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Introduction: Women's health, both in youth and adulthood, often faces reproductive health issues such as infections of the reproductive organs, including sexually transmitted infections (STIs). Education on STIs is essential for improving awareness and prevention. Objective: The aim of this study was to provide education about STIs to women of reproductive age and assess the improvement in their knowledge.  Method: This is a quantitative study with a quasi-experimental design using a one-group pretest and posttest approach. The sample consisted of 30 women of reproductive age, selected through total sampling. Data were collected using a questionnaire, and data analysis was performed using the Wilcoxon statistical test with a significance level of α = 0.05. Results: After receiving education on STIs, 19 respondents (63.3%) demonstrated good knowledge, 11 respondents (36.7%) had sufficient knowledge, and no respondents had poor knowledge. The analysis revealed a significance value of Sig < 0.05, indicating a significant effect of the education on improving knowledge about STIs in women of reproductive age. Conclusion: The study concluded that education significantly improved the knowledge of women of reproductive age about sexually transmitted infections, highlighting the importance of such educational interventions in promoting better reproductive health awareness.
The Effect of Deep Breath Relaxation Techniques on Pain of Labor Phase 1 Active Phase in Mothers Mability at Kolonodale Hospital North Morowali Regency Sesilia Tandondo, Hana; Yulianti, Yulianti; Irmayanti, Irmayanti
HEALTH SCIENCE & BIOMEDICAL JOURNAL Vol. 1 No. 1 (2025): April 2025 : Health Science & Biomedical Journal (HSBJ)
Publisher : Literasi Indonesia Emas (PT)

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Background: One of the fundamental efforts to reduce maternal mortality rate (MMR) is to minimize labor pain experienced by the mother. Labor pain can be managed through two methods: pharmacological and non-pharmacological. Pharmacological methods, which use chemical drugs, are often more expensive and may have adverse effects on both the mother and fetus. In contrast, non-pharmacological methods, such as relaxation techniques, are simpler, cheaper, and more effective, with no side effects. Objective: The purpose of this study was to determine the effect of breath relaxation techniques in reducing labor pain during the active phase I. Method: This research employed a quasi-experimental design with a one-group pretest and posttest approach. The study population consisted of 31 respondents selected through total sampling. Data were collected using a questionnaire, and data analysis was performed using the Wilcoxon statistical test with a significance level of α = 0.05. Results: Almost all respondents experienced a decrease in pain scale after being given the deep breathing relaxation method. Analysis of the Wilcoxon test results showed a P-value of <0.001, which is less than 0.05, indicating a significant effect of the deep breathing relaxation technique on reducing labor pain. Conclusion: The study concluded that the deep breathing relaxation technique significantly decreased the intensity of pain felt by women in the first active phase of labor.
Risk Factors and Relationship Erithrocyte Sediment Rate (ESR) in Hypertension Satisfactions Azmah Nikmatullah, Nurul; Aprilia, Nisa; Erikardo, Oktadio; Purbasari, Euis; Wirman, Adia Putra
HEALTH SCIENCE & BIOMEDICAL JOURNAL Vol. 1 No. 1 (2025): April 2025 : Health Science & Biomedical Journal (HSBJ)
Publisher : Literasi Indonesia Emas (PT)

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Introduction: Hypertension, defined as blood pressure greater than 140/90 mmHg, is a major public health issue globally. Several factors contribute to hypertension, including smoking, obesity, family history, co-morbidities, and the duration of hypertension. Monitoring blood pressure and associated markers such as the erythrocyte sedimentation rate (ESR) is critical to detect tissue damage and prevent complications. ESR serves as an important screening tool for the acute phase response and chronic diseases. Objective: This study aimed to determine the relationship between hypertension risk factors and erythrocyte sedimentation rate (ESR) levels. Method: This research employed a cross-sectional design with an experimental approach. Blood sedimentation rates were measured using the automatic vision-b method on blood samples with EDTA anticoagulant. Data were analyzed using the Mann-Whitney statistical test. Result: The results showed no significant relationship between age and gender with ESR levels (p > 0.05). However, there was a significant relationship between smoking, obesity, history of hypertension, co-morbidities, duration of hypertension, and elevated ESR levels (p < 0.05) in hypertensive patients at the Health Center in Duren Sawit District. Conclusion: Certain risk factors such as smoking, obesity, history of hypertension, co-morbidities, and the duration of hypertension are associated with increased erythrocyte sedimentation rates in hypertensive patients, while age and gender are not significantly related.
Gambaran Profil Lipid Pada Pasien Penyakit Jantung Koroner: Overview of Lipid Profiles in Patients with Coronary Heart Disease Ibrahim, Ikhsan; Aminah, Sitti; Hermawati
HEALTH SCIENCE & BIOMEDICAL JOURNAL Vol. 1 No. 2 (2025): August 2025 : Health Science & Biomedical Journal (HSBJ)
Publisher : Literasi Indonesia Emas (PT)

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Latar Belakang: Penyakit Jantung Koroner (PJK) merupakan gangguan jantung akibat penyempitan pembuluh darah koroner yang menghambat aliran darah ke otot jantung. Salah satu faktor risiko utama PJK adalah dislipidemia, yaitu gangguan kadar lipid darah seperti kolesterol total, trigliserida, LDL, dan HDL.Tujuan: Penelitian ini bertujuan untuk mendeskripsikan gambaran profil lipid pada pasien PJK. Metode: Penelitian ini menggunakan desain deskriptif kuantitatif. Sampel berupa 59 data hasil pemeriksaan laboratorium profil lipid pasien PJK yang memenuhi kriteria inklusi. Parameter yang diperiksa meliputi kolesterol total, trigliserida, LDL, dan HDL. Analisis data dilakukan secara deskriptif menggunakan SPSS. Hasil: Dari 59 pasien PJK, ditemukan bahwa 30 orang (50,8%) memiliki kadar kolesterol total tinggi (>240 mg/dL), 31 orang (52,5%) memiliki kadar trigliserida optimal (<150 mg/dL), 21 orang (35,6%) berada pada kategori borderline LDL (130–159 mg/dL), dan 32 orang (54,2%) memiliki kadar HDL pada kategori optimal (40–60 mg/dL). Kesimpulan: Mayoritas pasien PJK memiliki kadar kolesterol total yang tinggi, kadar trigliserida dan HDL dalam kategori optimal, serta kadar LDL pada batas tinggi.  
"Inhibitory Activity Test of White Turmeric (Curcuma zedoaria) Extract Against Escherichia coli Bacteria" maulidayanti, sharfina; Nafis, Nidhal Mijwan; Situmorang, Ing Mayfa Br; Armawan, Ladyka Viola Aulia
HEALTH SCIENCE & BIOMEDICAL JOURNAL Vol. 1 No. 2 (2025): August 2025 : Health Science & Biomedical Journal (HSBJ)
Publisher : Literasi Indonesia Emas (PT)

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Introduction: Escherichia coli bacteria are microorganisms that are usually found in the digestive tract in both animals and humans. Belonging to the Enterobacteriaceae family, E. coli has a cell size of between 2.0 to 6.0 micrometers by a diameter of 1.1 to 1.5 micrometers. These bacteria are straight rods and They can be found in singular, paired, or in short chains. E. Objective: This study aims to evaluate the inhibition of white turmeric extract (Curcuma zedoaria) against the pathogenic bacteria Escherichia coli, which is one of the causes of gastrointestinal infections or diarrheal diseases. Method: White turmeric extraction was carried out using the maceration method with a 96% ethanol solvent, which was then tested on Escherichia coli bacteria by the Disc diffusion method, using paper discs that had been soaked in various concentrations of onion extract (15%, 25%, 50%). The inhibition zones formed around the disc are observed and measured to determine the effectiveness of inhibition. Result: Based on research on the inhibitory effect of white turmeric extract on the growth of Escherichia coli bacteria, a concentration of 15% resulted in an average diameter of 7.1 mm (resistant), 25% resulted in a diameter of 9.3 mm (resistant), and 50% resulted in a diameter of 11.3 mm (resistant) on Escherichia coli bacteria. Conclusion: The conclusion of this study is that the more effective concentration to inhibit the growth of Escherichia coli bacteria is at 50% concentration.
Aktivitas Antibakteri Ekstrak Umbi Bawang Merah (Allium Cepa L.) terhadap Bakteri Staphylococcus aureus: Antibacterial Activity of Shallot (Allium cepa L.) Tuber Extract against Staphylococcus aureus Nur, Jumriah; Situmorang, Ing Mayfa Br; Maulidayanti, Sharfina; Mahendra, Robert Ariyan
HEALTH SCIENCE & BIOMEDICAL JOURNAL Vol. 1 No. 2 (2025): August 2025 : Health Science & Biomedical Journal (HSBJ)
Publisher : Literasi Indonesia Emas (PT)

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Latar Belakang: Staphylococcus aureus merupakan bakteri patogen yang mampu menyebabkan penyakit infeksi pada manusia. Adanya peningkatan resistensi antibiotik pada bakteri tersebut, sehingga perlu dilakukan upaya untuk mencari alternatif pengobatan berbasis bahan alam. Tujuan: untuk mengetahui aktivitas antibakteri ekstrak bawang merah (Allium cepa L.) terhadap bakteri S. aureus. Metode:  penelitian ini dilakukan di Laboratorium Mikrobiologi STIKes Prima Indonesia dari bulan April-Juni 2025. Desain penelitian menggunakan rancangan eksperimental laboratorium  dengan metode paper-disk (disk diffusion) pada media Mueller Hinton Agar (MHA). Ekstrak bawang merah diperoleh melalui metode maserasi dengan menggunakan etanol 96%, selanjutnya diuji pada berbagai konsentrasi (10%, 15% dan 20%). Zona Hambat diukur setelah inkubasi 24 jam pada suhu 37oC. Hasil: penelitian menunjukan bahwa ekstrak bawang merah memiliki aktivitas antibakteri terhadap bakteri S. aureus dengan zona hambat terbesar pada 20% yaitu sebesar 11,6 mm dengan kriteria lemah, sedangkan konsentrasi terendah 10% menghasilkan zona hambat rerata 8,6 mm dengan kriteria lemah. Kesimpulan: pada penelitian ini adalah ekstrak umbi bawang merah memiliki potensi sebagai agen antibakteri alami terhadap S. aureus dengan efektivitasnya meningkat seiring dengan kenaikan konsentrasi ekstrak.  
Gangguan Elektrolit pada Balita Penderita Diare; Sebuah Pendekatan Klinis: Electrolyte Disturbances among Children Under Five with Diarrhea; A Clinical Approach Susanti; Lilis; Zasqiah, Dela Namirah
HEALTH SCIENCE & BIOMEDICAL JOURNAL Vol. 1 No. 2 (2025): August 2025 : Health Science & Biomedical Journal (HSBJ)
Publisher : Literasi Indonesia Emas (PT)

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Latar belakang: Diare masih menjadi masalah kesehatan utama pada balita di Indonesia dan merupakan penyebab kematian kedua tertinggi. Salah satu komplikasi utama dari diare adalah dehidrasi yang dapat menyebabkan gangguan keseimbangan elektrolit, khususnya natrium, kalium, dan klorida. Tujuan: Untuk mengetahui gambaran kadar elektrolit (natrium, kalium, dan klorida) pada balita penderita diare. Methode: Penelitian ini menggunakan desain deskriptif kuantitatif dengan pendekatan cross-sectional. Subjek penelitian adalah 41 balita penderita diare usia 0–5 tahun. Pemeriksaan kadar elektrolit dilakukan menggunakan alat elektrolit analyzer selama periode penelitian berlangsung. Hasil: Sebagian besar responden berjenis kelamin laki-laki (51,22%). Kadar natrium rendah ditemukan pada 53,66% balita, sedangkan 46,34% memiliki kadar natrium normal. Kadar kalium rendah ditemukan pada 26,83%, normal pada 70,73%, dan tinggi pada 2,44%. Kadar klorida rendah ditemukan pada 7,32%, normal pada 90,24%, dan tinggi pada 2,44%. Kesimpulan: Gangguan keseimbangan elektrolit, terutama hiponatremia dan hipokalemia, cukup sering ditemukan pada balita penderita diare. Tidak terdapat perbedaan bermakna dalam kadar elektrolit berdasarkan jenis kelamin maupun usia. Pemeriksaan elektrolit perlu menjadi bagian penting dalam penanganan klinis diare pada balita.
Hubungan Usia dan Berat Badan terhadap Derajat Proteinuria pada Ibu Hamil dengan Hipertensi: Correlation between Age and Body Weight with the Degree of Proteinuria among Hypertensive Pregnant Women Thalib, Kiki Uniatri; Lilis
HEALTH SCIENCE & BIOMEDICAL JOURNAL Vol. 1 No. 2 (2025): August 2025 : Health Science & Biomedical Journal (HSBJ)
Publisher : Literasi Indonesia Emas (PT)

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Latar Belakang: Hipertensi pada kehamilan, termasuk pre-eklampsia, merupakan salah satu penyebab utama morbiditas dan mortalitas maternal. Pemeriksaan protein urin dapat digunakan sebagai indikator adanya kerusakan ginjal akibat hipertensi pada ibu hamil. Tujuan: Penelitian ini bertujuan untuk mengetahui karakteristik protein urin pada ibu hamil dengan hipertensi berdasarkan usia dan indeks massa tubuh (IMT). Metode: Penelitian ini menggunakan desain deskriptif kualitatif dengan teknik total sampling. Sampel terdiri dari 32 ibu hamil trimester III dengan hipertensi. Pemeriksaan protein urin dilakukan menggunakan metode carik celup dengan pembacaan hasil menggunakan urine analyzer (Urit-50). Hasil: Dari 32 sampel urin yang diperiksa, ditemukan hasil protein urin negatif pada 18 orang (56,25%), positif 1 (+) pada 8 orang (25%), positif 2 (++) pada 3 orang (9,38%), dan positif 3 (+++) pada 3 orang (9,38%). Rata-rata usia responden adalah 32 tahun, sedangkan rata-rata IMT sebesar 30,65 kg/m² yang termasuk kategori obesitas. Kesimpulan: Mayoritas ibu hamil dengan hipertensi memiliki hasil pemeriksaan protein urin negatif, dengan sebagian kecil menunjukkan proteinuria positif. Rata-rata responden berada pada usia reproduktif dan memiliki IMT dalam kategori obesitas.

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