cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kab. sleman,
Daerah istimewa yogyakarta
INDONESIA
Jurnal Ilmiah Farmasi
Published by Universitas Islam Indonesia
ISSN : 16938666     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
JIF merupakan jurnal yang dikelola oleh Prodi Farmasi Universitas Islam Indonesia, dan diterbitkan dua kali dalam setahun. Jurnal ini dirancang sebagai sarana publikasi penelitian yang mencakup secara rinci sejumlah topik dalam bidang farmasi yang berkaitan dengan farmasi sains dan teknologi serta klinik dan komunitas. Jurnal ini menyediakan sebuah forum sebagai sarana pertukaran gagasan dan dan informasi antar peneliti, akademisi dan praktisi sehingga diharapkan mampu mendukung dan menginisiasi berbagai penelitian terkini yang terkait dengan ilmu kefarmasian. Hasil penelitian yang disajikan dalam jurnal ini diharapkan dapat memberikan kontribusi bagi perkembangan ilmu di bidang farmasi dan kesehatan.
Arjuna Subject : -
Articles 269 Documents
 21   22   23   24   25 
Bioactivity Guided Isolation from Ethanolic Extract of Faloak Stem Bark (Sterculia quadrifida R.Br) Jennifer Ruskim; Ryanto Budiono; Kartini; Nina Dewi Oktaviyanti; Finna Setiawan
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art11

Abstract

Background: Free radicals consist of one or more unpaired electrons in an outer orbit that causes them to be more reactive. This will lead to oxidative stress, which is one of the major causes of degenerative diseases such as cancer, diabetes mellitus, and stroke. Therefore, consuming sufficient antioxidants can prevent oxidative stress. Faloak (Sterculia quadrifida R. Br.) is one of the endemic medicinal plants in East Nusa Tenggara and is a resource of antioxidants that are supported by scientific evidence. Until now, information about the antioxidant compounds in Faloak was limited. Objective: This study aims to identify active compounds in an 80% ethanol extract from faloak bark as antioxidants based on their TLC-bioautography profiles using an ABTS assay. Method: The methods of this study start with the preparation of simplicia, fractination using kinetic maceration, compound group identification and TLC-bioautography, separation using column chromatography [stationary phase: silica H60; mobile phase: 2-propanol: chloroform: acetic acid glacial (5:1:0,5)], identification using a UV-Vis spectrophotometer, and antioxidant activity determination of the extract and isolate using an ABTS assay. Result: Through this study, a subfraction (SFFE A) with a brown-red color and a blue spot under UV 365 nm and an Rf value of 0.65 was obtained. This subfraction (SFFE A) was predicted to be a polyphenol compound. The inhibition percentages of 125, 250, and 500 ppm successively are 80,93%; 95,54%; and 96,69%.Conclusion: The active isolate of ethanol extracting 80% of the faloak stem bark is suspected to be a polyphenol group and has strong antioxidant activity. Intisari Latar belakang: Radikal bebas merupakan suatu molekul yang terdiri atas satu atau lebih elektron tanpa pasangan pada orbital terluar. Hal ini dapat menyebabkan tubuh mengalami stress oksidatif sehingga memicu munculnya berbagai penyakit degeneratif, seperti kanker, diabetes mellitus, serta stroke. Oleh karena itu, dengan mengonsumsi antioksidan yang cukup dapat mencegah stres oksidatif. Faloak (Sterculia quadrifida R. Br.) merupakan salah satu tanaman obat endemik di NTT (Nusa Tenggara Timur) yang berpotensi digunakan sebagai sumber antioksidan kuat yang didukung oleh studi ilmiah. Hingga saat ini, informasi terkait senyawa yang berperan langsung sebagai antioksidan pada tanaman ini masih terbatas. Tujuan: Penelitian ini bertujuan untuk mengidentifikasi senyawa aktif dari ekstrak etanol 80% kulit batang faloak yang berperan sebagai antioksidan berdasarkan profil KLT-bioautografi dengan metode ABTS. Metode: Metode kerja dimulai dengan preparasi simplisia, fraksinasi dengan metode maserasi kinetik, identifikasi golongan senyawa dan KLT bioautografi, pemisahan dengan kromatografi kolom [(fase diam: silika H60; fase gerak: 2-propanol:kloroform:asam asetat glasial (5:1:0,5)], dan identifikasi senyawa menggunakan spektrofotometer UV-Vis, dan pengujian aktivitas antioksidan pada ekstrak dan isolate menggunakan metode ABTS. Hasil: Melalui penelitian ini, didapatkan subfraksi (SFFE A) berwarna merah-kecoklatan yang memiliki noda berfluoresensi biru pada UV 366 dengan nilai Rf 0,65 dengan pengamatan UV 365 nm. Sub fraksi (SFFE A) yang didapatkan diduga merupakan senyawa golongan polifenol. Persentase inhibisi subfraksi pada konsentrasi 125, 250, dan 500 ppm secara berturut-turut adalah 80,93; 95,54; dan 96,69%. Kesimpulan: Isolat aktif dari ekstrak etanol 80% kulit batang faloak diduga merupakan golongan polifenol dan memiliki aktivitas antioxidan yang kuat. Kata kunci: faloak (Sterculia quadrifida R.Br), antioksidan, isolasi, maserasi kinetik, kromatografi kolom
Uji Aktivitas Antioksidan Ekstrak Etanol 70% dan 96% Kulit Batang Tandui (Mangifera rufocostata Kosterm.) dengan Metode DPPH Revita Saputri; Eka Fitri Susiani; Souva Asvia
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art8

Abstract

Background: The genus Mangifera has been reported to have many activities as a natural antioxidant; one of them is the tandui plant (Mangifera rufucostata Kosterm). The study of 70% and 96% ethanol extracts of tandui leaves has shown potential as an antioxidant with the DPPH method, which is a strong category. The potential as an antioxidant in leaves is also possible in other parts, such as stem bark.Objective: This study is to determine the antioxidant potential of tandui stem bark in 70% and 96% ethanol solvents with the DPPH method.Methods: The tandui stem bark was extracted using the soxhletation method with 70% and 96% ethanol solvents. Potential antioxidant activity was measured using a UV-Vis spectrophotometer and the positive control, quercetin.Results: Antioxidant activity results showed that the IC50 of 70% ethanol extract of tandui stem bark (EE70%KBT) was 9.657 µg/mL, the IC50 of 96% ethanol extract of tandui stem bark (EE96% KBT) was 6.362 µg/mL and the IC50 of positive control quercetin was 3.441 µg/mL.Conclusion: The results showed that tandui stem bark extracted using 70% and 96% ethanol has a strong potential as a natural antioxidant (very strong category) using the DPPH method. Intisari Latar belakang: Genus Mangifera dilaporkan telah memiliki banyak aktivitas sebagai antioksidan alami, salah satu jenis dari genus tersebut adalah tumbuhan tandui (Mangifera rufocostata Kosterm.). Penelitian terhadap ekstrak etanol 70% dan 96% daun tandui telah terbukti berpotensi sebagai antioksidan dengan metode DPPH dengan kategori kuat. Potensi sebagai antioksidan pada daun juga dimungkinkan pula pada bagian lainnya seperti kulit batang. Tujuan: Tujuan penelitian ini adalah melihat potensi antioksidan kulit batang tandui menggunakan pelarut etanol 70% dan etanol 96% dengan metode DPPH.Metode: Kulit batang tandui diekstraksi secara sokletasi dengan pelarut etanol 70% dan etanol 96%. Potensi aktivitas antioksidan dianalisis menggunakan spektrofotometer UV-Vis dan kontrol positif yaitu kuersetin. Hasil: Hasil penelitian menunjukkan bahwa nilai IC50 ekstrak etanol 70% kulit batang tandui (EE70%KBT) sebesar 9,657 µg/mL, nilai IC50 ekstrak etanol 96% kulit batang tandui (EE96%KBT) sebesar 6,362 µg/mL dan nilai IC50 kontrol positif kuersetin yaitu 3,441 µg/mL.Kesimpulan: Hasil penelitian tersebut menunjukkan bahwa kulit batang tandui yang diekstraksi menggunakan etanol 70% dan etanol 96% memiliki potensi yang besar sebagai antioksidan alami (kategori yang sangat kuat) berdasarkan metode DPPH.Kata kunci : Mangifera rufocostata Kosterm., kulit batang tandui, antioksidan, DPPH
The relationship between patient knowledge and behavior of NSAID self-medication at Pharmacy X in Banjarmasin Guntur Kurniawan; Muhammad Reza Pahlevi; Helmina Wati; Wulan Ageng Sujatmiko
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art10

Abstract

Background: Self-medication is a way of providing treatment for oneself without a doctor's prescription or the unwanted effects of a drug. Knowledge about diseases and drugs is needed to determine the right behavior for self-medication. One of the drugs used by the public is the non-steroidal anti-inflammatory drug (NSAID).Objective: The purpose of this research was to evaluate the correlation between patient knowledge of using NSAIDs and patient behavior at Pharmacy X, located in Banjarmasin. Method: This research used a quantitative method with a cross-sectional approach. This study included 40 patients who visited Pharmacy X in Banjarmasin for 1 month. The respondents were enrolled using the accidental sampling technique. The data was obtained with a questionnaire and analyzed with the Pearson Chi Square method. Results: The outcomes of this study indicated that the knowledge level of respondents on NSAIDs was classified as poor (40%). The behavior of subjects who use NSAIDs for self-medication was categorized as negative (62.5%). This study also showed an association between knowledge and habits of self-medication using NSAIDs at pharmacy X in Banjarmasin, with a significance value of 0.003 (p <0.05).Conclusion: There is a direct proportional relationship between knowledge and self-medication behavior when taking NSAIDs, with a significance value of 0.003 (p < 0.05). Intisari Latar belakang: Swamedikasi adalah cara melakukan pengobatan sendiri tanpa resep dokter maupun pengetahuan tentang reaksi obat yang tidak diinginkan. Pengetahuan tentang penyakit dan obat sangat dibutuhkan untuk menentukan perilaku yang benar dalam pemilihan obat secara mandiri. Salah satu jenis obat yang digunakan oleh masyarakat adalah obat golongan Non-Steroidal Anti-Inflammatory Drugs (NSAID).Tujuan: Penelitian bertujuan untuk mengetahui hubungan antara pengetahuan pasien tentang swamedikasi obat golongan NSAID dengan perilaku pasien di Apotek X Banjarmasin.Metode: Penelitian ini menggunakan metode kuantitatif dengan pendekatan cross-sectional. Studi ini melibatkan 40 responden yang berkunjung di Apotek X Banjarmasin selama 1 bulan. Pengambilan sampel menggunakan teknik accidental sampling. Pengumpulan data menggunakan kuesioner dan data dianalisis dengan uji Pearson Chi Square.Hasil: Hasil riset menunjukkan bahwa pengetahuan responden tentang NSAID termasuk dalam kategori “kurang baik” sebanyak 40%. Perilaku pasien yang menggunakan swamedikasi obat NSAID termasuk dalam kategori “berperilaku negatif” sebanyak 62,5%. Pengetahuan berhubungan dengan perilaku swamedikasi NSAID di Apotek X Banjarmasin dengan nilai signifikansi 0,003 (p<0,05). Kesimpulan: Pengetahuan pasien berbanding lurus dengan perilaku swamedikasi obat golongan NSAID.Kata kunci: tingkat pengetahuan, perilaku, swamedikasi, NSAID
Analisis Guessability Score dan Pemahaman Piktogram Kefarmasian pada Pasien Tuberkulosis Ema Rachmawati; Dhea Nanda Aliefia; Fransiska Maria Christianty
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art3

Abstract

Background: Pharmaceutical pictograms can be used to help tuberculosis patients understand treatment information, especially those with low reading skills.Objective: This study aimed to analyze the guessability score and the level of understanding of pharmaceutical pictograms related to the use of TB drugs.Method: This was an observational study with a cross-sectional design. The sample used was 96 TB patients who were actively undergoing treatment. The guessability score and level of understanding were analyzed descriptively, while the relationship between socio-demographic characteristics and the level of understanding of pharmaceutical pictograms was analyzed using the Chi-square test.Results: The results showed that the guessability score of 23 pictograms tested on respondents varied greatly, with a score range of 29.2%–99%. Meanwhile, the level of respondents' understanding of pharmaceutical pictograms related to TB treatment was in the "fair" category. The Chi-square test showed a significant relationship between the level of respondents’ education and their understanding of pharmaceutical pictograms.Conclusion: The findings of this study demonstrated that not all pictogram images were simple for respondents to understand. It is necessary to choose pictogram images that are easy for respondents to understand or redesign pictogram images so that they can be used to improve the effectiveness of drug information delivery to patients. Intisari Latar belakang: Gambar piktogram kefarmasian dapat digunakan untuk membantu pasien tuberkulosis memahami informasi pengobatan, khususnya untuk pasien dengan tingkat literasi rendah. Tujuan: Penelitian bertujuan untuk mengukur kemampuan menerka (guessability score) dan pemahaman responden terhadap piktogram kefarmasian terkait pengobatan tuberkulosis.Metode: Penelitian observasional cross-sectional terhadap 96 responden pasien TB yang aktif menjalani pengobatan. Guessability score dan tingkat pemahaman dianalisis secara deskriptif, sedangkan hubungan karakteristik sosio-demografi dengan tingkat pemahaman dianalisis dengan uji Chi-square.Hasil: Hasil penelitian menunjukkan kemampuan menerka (guessability score) terhadap 23 gambar piktogram sangat beragam, dengan rentang skor 29,2% – 99%. Sedangkan tingkat pemahaman responden terhadap piktogram kefarmasian terkait pengobatan TB masuk dalam kategori “cukup”. Uji Chi-square menunjukkan adanya hubungan yang signifikan antara tingkat pendidikan terhadap tingkat pemahaman responden.Kesimpulan: Tidak semua gambar piktogram kefarmasian mudah dipahami oleh responden. Untuk itu perlu memilih gambar piktogram yang mudah dipahami reponden atau melakukan desain ulang gambar piktogram sehingga dapat digunakan untuk meningkatkan efektivitas pemberian informasi obat pada pasien.Kata kunci: guessability score, pemahaman, piktogram kefarmasian, tuberculosis
Pengetahuan, sikap, dan perilaku konsumsi suplemen dan obat tradisional mahasiswa Universitas Jember saat pandemi COVID-19 Dhita Evi Aryani; Agnes Jovanka; Ema Rachmawati; Sinta Rachmawati; Ika Norcahyanti; Antonius Nugraha Widhi Pratama; Afifah Machlaurin; Fransiska Maria C.
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art6

Abstract

Background: The COVID-19 pandemic has been going on for 3 years since it was established by the WHO in 2020. COVID-19 can be prevented by improving the immune system by consuming supplements and traditional medicines.Objective: This study aimed to determine knowledge, attitudes, and behaviors towards supplements and traditional medicines used by Jember University students during the COVID-19 pandemic.Method: This research design was a cross-sectional observational analytic study. The sample size was 606 Jember University students. Samples were taken using the convenience sampling method with online questionnaire instruments. The data obtained were analyzed by Chi-Square, Fisher’s Exact, and descriptive.Results: During the pandemic, 45.9% of respondents consumed supplements and/or traditional remedies to maintain health (80.6%). Knowledge and attitudes showed a significant difference (p≤0.05), so it was concluded that knowledge affects attitudes towards supplements and traditional medicines used. Supplement use behavior showed that some were taking supplements and some were not for various reasons.Conclusion: The majority of respondents have knowledge and attitudes in the medium category. Sociodemographic factors that influence the knowledge and attitudes of Jember University students toward supplements and traditional medicine used during the COVID-19 pandemic were level of education and discipline. Respondents' behavior showed that most of them did not take supplements because they had been vaccinated. Intisari Latar belakang: COVID-19 sudah berlangsung selama 3 tahun semenjak WHO menetapkan sebagai pandemi di tahun 2020. COVID-19 dapat dicegah dengan meningkatkan daya tahan tubuh yang salah satu caranya adalah mengkonsumsi suplemen dan obat tradisional.Tujuan: Penelitian ini bertujuan mengetahui pengetahuan, sikap, dan perilaku konsumsi suplemen dan obat tradisional mahasiswa Universitas Jember saat pandemi COVID-19. Metode: Penelitian ini bersifat analitik observasional dengan jumlah sampel 606 mahasiswa Universitas Jember dengan desain cross-sectional yang diambil metode convenience sampling dengan instrumen pengumpulan data berupa kuesioner daring. Data yang didapatkan dianalisis dengan uji Chi-square, Fisher’s Exact dan deskriptif. Hasil: Terdapat 45,9% responden mengkonsumsi suplemen dan/atau obat tradisional selama masa pandemi untuk untuk menjaga kesehatan (80,6%). Pengetahuan dan sikap menunjukkan perbedaan signifikan (p≤0,05), sehingga diketahui bahwa pengetahuan dapat memengaruhi sikap. Perilaku pengunaan suplemen menunjukkan ada yang mengkonsumsi suplemen dan ada yang tidak dengan berbagai alasan.Kesimpulan: Mayoritas responden mempunyai pengetahuan dan sikap dalam kategori sedang (45,5%; 50,8%), dengan faktor sosiodemografi yang memengaruhi pengetahuan dan sikap mahasiswa Universitas Jember dalam konsumsi suplemen dan obat tradisional adalah tingkat pendidikan dan rumpun ilmu. Perilaku responden menunjukkan mayoritas mereka tidak mengkonsumsi suplemen karena sudah vaksin.Kata kunci: Pengetahuan, perilaku, suplemen, obat tradisional, mahasiswa, COVID-19
EFEKTIVITAS KOMBINASI EKSTRAK ETANOL 70% DAUN RAMANIA (Bouea macrophylla Griffith) dan GLIBENKLAMID DENGAN METODE INTOLERANSI GLUKOSA Karunita Ika Astuti; Fitriyanti Fitriyanti; Hadirvika Tjuthiyanda
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art4

Abstract

Background: Diabetes mellitus is a chronic disease in which the body cannot produce insulin effectively. Glibenclamide is often used either in single preparations or in combination. Ramania (Bouea macrophylla Griffith) is one of the typical Kalimantan plants for diabetes treatment.Objective: Determine the best concentration of a combination of the extract of ramania leaves with glibenclamide as an antidiabetic.Method: This study used the oral glucose tolerance test (OGTT). Twenty-four mice were divided into six groups: a negative control (Na-CMC0.5%), a glucose control, a positive control (glibenclamide 5 mg/kgBW), and a combination group of 70% ethanol extract of ramania leaves (125, 250, and 500 mg/kgBW) with glibenclamide 5 mg/kgBW. Mice were induced by oral glucose to experience hyperglycemia. The results were measured at 0 minutes before treatment and at 30, 60, 90, and 120 minutes.Results: A combination extract of ramania leaves and glibenclamide with doses of 25 and 500 mg had an effect on glucose-induced male white mice.Conclusion: The best combination dose of 500 mg of extract and glibenclamide was obtained. Intisari Latar belakang: Diabetes Melitus merupakan kondisi kronis yang disebabkan kurang efektifnya insulin bekerja. Glibenklamid merupakan salah satu obat antidiabetes oral yang sering digunakan baik dalam sediaan tunggal ataupun kombinasi. Ramania (Bouea macrophylla Griffith) merupakan tanaman khas Kalimantan yang dapat digunakan sebagai pengobatan diabetes. Tujuan: Mengetahui konsentrasi terbaik dari kombinasi ekstrak etanol 70% daun ramania dengan glibenklamid sebagai antidiabetes. Metode: Uji yang digunakan dalam penelitian ini adalah uji toleransi glukosa oral (UTGO). Hewan uji menggunakan mencit putih jantan yang dibagi menjadi enam kelompok, yaitu kelompok kontrol (Na-CMC 0,5%), kontrol positif (glibenklamid 5 mg/kg BB), kelompok kombinasi ekstrak etanol 70% daun ramania 125; 250; dan 500 mg/kgBB - glibenklamid 5 mg/kg BB. Mencit pada semua kelompok diinduksi glukosa secara oral agar mengalami hiperglikemia. Kadar glukosa darah ditentukan pada menit ke-0, 30, 60, 90, 120 setelah induksi glukosa. Selanjutnya dilakukan perhitungan nilai AUC0-120 serta dianalisis dengan menggunakan SPSS bertaraf kepercayaan 95%.Hasil: Semua kelompok dosis kombinasi ramania-glibenklamid menunjukkan tidak adanya perbedaan bermakna dengan kontrol positif sehingga berdasarkan nilai AUC0-120 menunjukkan kombinasi ekstrak dan glibenklamid dengan dosis 125 mg/KgBB memberikan efek antihiperglikemik terbaik.Kesimpulan: Diperoleh kombinasi terbaik dengan dosis 125 mg/KgBB yang dikombinasikan dengan glibenklamid.Kata kunci : Ramania, antidiabetes, intoleransi glukosa, kombinasi, glibenklamid
Karakterisasi dan Penetapan Kadar Fenol Total Ekstrak Etanol 96% Umbi Bawang Dayak (Eleutherine bulbosa Urb.) Berdasarkan Variasi Waktu Tumbuh Tanaman Rahmi Muthia; Kartini; Wahyudin Bin Jamaludin; Lulu Damayanti
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art9

Abstract

Background: Bawang dayak (Eleutherine bulbosa Urb.) grows widely in Kalimantan. This plant can be used as a raw material for medicine and is known to contain phenolic compounds that have antibacterial, antioxidant, and anti-inflammatory properties. The quality of the raw material of a plant determines its pharmacological activity. This is, of course, related to the content of compounds or active substances. One factor that plays an important role is the age of harvest, which can affect the content of compounds both qualitatively and quantitatively.Objective: To determine the simplicia characterization and total phenol content in bulbs of bawang dayak extracted using 96% ethanol, which were harvested at the ages of 1, 2, and 3 months.Method: Bulbs of bawang dayak are used in the 1st, 2nd, and 3rd months with several testing stages, namely organoleptic tests, macroscopic tests, and microscopic tests. Further qualitative analysis used TLC with chloroform and methanol (8:2) as the mobile phases. In the quantitative test, we used a UV-Via spectrophotometer with the folin-ciocalteau reagent and the gallic acid comparison.Results: The TLC test showed a positive result for phenol, which was marked after being sprayed with 1% FeCl3, a black spot appeared. The results of the determination of total phenol content in the 1st, 2nd, and 3rd months, respectively, were 59.196 ± 0.057, 76.596 ± 0.057, and 60.63 ± 0.2 mg/g GAE. Conclusion: The data above shows that the highest total phenol content is in the second month. Intisari Latar belakang: Bawang dayak (Eleutherine bulbosa Urb.) tumbuh menyebar di wilayah Kalimantan. Tanaman ini dapat digunakan sebagai bahan baku obat dan diketahui mengandung senyawa fenol yang memiliki kemampuan sebagai antibakteri, antioksidan dan antiinflamasi. Kualitas bahan baku suatu tanaman sangat menentukan aktivitas farmakologinya. Hal ini tentunya berkaitan dengan kandungan senyawa atau zat aktif. Salah satu faktor yang berperan penting yaitu umur panen yang dapat mempengaruhi kandungan senyawa baik secara kualitatif maupun kuantitatif.Tujuan: Mengetahui karakterisasi simplisia dan kadar fenol total pada umbi bawang dayak yang diekstraksi menggunakan etanol 96% yang dipanen pada umur tanaman 1, 2 dan 3 bulan.Metode: Umbi bawang dayak yang digunakan bulan ke-1, 2 dan 3 dengan beberapa tahap pengujian yaitu uji organoleptis, uji makroskopis, serta uji mikroskopis. Selanjutnya analisis kualitatif menggunakan KLT dengan fase gerak kloroform: metanol (8:2). Pada uji kuantitatif menggunakan alat spektrofotometer UV-Vis dengan reagen folin-ciocalteau dan pembanding asam galat.Hasil: Uji KLT menunjukkan hasil positif fenol ditandai setelah disemprot dengan FeCl3 1% terdapat noda berwarna hitam. Hasil penetapan kadar fenol total bulan pertama, kedua dan ketiga berturut-turut yaitu 59,196 ± 0,057; 76,596 ± 0,057, dan 60,63 ± 0,2 mg/g GAE.Kesimpulan: Kandungan total fenol tertinggi pada ekstrak umbi bawang dayak terdapat pada bulan kedua.Kata kunci: Fenol, KLT, spektrofotometer UV-Vis
The study of conformity of the pharmaceutical service in Puskesmas Bogor City towards PMK No. 74, 2016 Nhadira Nhestricia; Hero Prasetio Kusworo; Lusi Agus Setiani
Jurnal Ilmiah Farmasi 2023: Special Issue
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.specialissue2023.art12

Abstract

Background: Improving the quality of pharmaceutical services requires a change in the old product-oriented paradigm (drug-oriented) into a new patient-oriented paradigm (patient-oriented) by executing pharmaceutical care. Improving the quality of pharmaceutical services to people who have direct contact through primary health care as the first-level health facility refers to PMK No. 74 of 2016.Objective: This study aims to determine the description of the implementation of pharmaceutical service standards at the Primary Health care facility in Bogor City for the 2022 period based on PMK No. 74 of 2016.Method: This study used a descriptive approach with an exploratory research type. Retrieval of data using questionnaire instruments and observation checklists The research was conducted for six months, from April to September 2022. The population in this study (24 primary health care and 24 pharmacy installation heads as respondents).Results: Based on the research results, the description of the implementation of pharmaceutical service standards at Bogor City Primary Health Care, based on PMK No. 74 of 2016, for the 2022 period showed that the average value of the questionnaire and observation instruments in the fields of management of pharmaceutical supplies and medical consumables (BMHP), clinical pharmacy services, and pharmaceutical quality control had successive values of 94.87, 85.5, and 100% (very good). The results of the value of the availability of pharmaceutical human resources were 95.83% (very good).Conclusion: The conclusion of the implementation of pharmaceutical services at the Bogor City Primary Health Care is in accordance with the pharmaceutical service standards at the Primary Health Care based on PMK No. 74 of 2016. Intisari Latar belakang: Peningkatan kualitas pelayanan kefarmasian menuntut adanya perubahan paradigma lama yang berorientasi terhadap produk (drug oriented) menjadi paradigma berkembang pada era saat ini yang berorientasi pada pasien (patient oriented) dengan melaksanakan pharmaceutical care. Peningkatan kualitas pelayanan kefarmasian pada masyarakat yang berhubungan langsung melalui puskesmas sebagai fasilitas kesehatan tingkat pertama yang merujuk pada PMK No. 74 Tahun 2016. Tujuan: Penelitian ini bertujuan untuk mengkaji kesesuaian implementasi standar pelayanan kefarmasian di Puskesmas Kota Bogor terhadap PMK No 74 Tahun 2016.Metode: Penelitian ini menggunakan pendekatan deskriptif dengan jenis penelitian eksploratif. Pengambilan data menggunakan instrumen kuisioner dan daftar tilik observasi. Penelitan dilakukan selama 6 bulan sejak April – September 2022. Populasi dalam penelitian ini adalah kepada kepala instalasi farmasi di seluruh Puskesmas Kota Bogor.Hasil: Implementasi standar pelayanan kefarmasian Puskesmas Kota Bogor berdasarkan PMK No. 74 tahun 2016 periode 2022 didapatkan hasil nilai rata-rata instrumen kuesioner dan observasi di bidang Pengelolaan Sediaan Farmasi dan Bahan Medis Habis Pakai (BMHP), pelayanan farmasi klinik serta pengendalian mutu kefarmasian memiliki nilai berturutu-turut sebesar 94,87; 85,5; dan 100% (sangat baik). Hasil nilai ketersediaan SDM kefarmasian sebesar 95,83% (sangat baik). Kesimpulan: Pelayanan kefarmasian di Puskesmas Kota Bogor telah sesuai dengan PMK No. 74 Tahun 2016.Kata kunci: pelayanan farmasi; permenkes; puskesmas
Quality of Life and Costs of Illness of Dengue Patients at Pku Muhammadiyah Yogyakarta and Bantul Boisi, Cici Feronika; Purwanto, Barkah Djaka; Supadmi, Woro; Faridah, Imaniar Noor; Perwitasari, Dyah Aryani
Jurnal Ilmiah Farmasi Vol. 20 No. 2 (2024): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol20.iss2.art5

Abstract

Background: The manifestation of dengue is a decrease in hematocrit and platelet levels, leading to a decrease in the patient’s quality of life and having an impact on the patient’s medical costs.Objective: This study objective was to ascertain the quality of life and medical costs associated with dengue patients.Method: This study employed a cross-sectional design at PKU Muhammadiyah Hospitals in Bantul and Yogyakarta from January to August in 2023. Pediatric patients’ quality of life was assessed using the EQ-5D-Y questionnaire, while adult patients’ using the EQ-5D-5L questionnaire. Data on patients’ medical costs was obtained from the hospital's financial database. The data were then analyzed descriptively and presented as a percentage of quality of life and average medical costs.Results: The results showed that pediatric DF patients in both hospitals reported anxiety and depression, with percentages of 100% (Yogyakarta) and 75% (Bantul), respectively. Meanwhile, most adult DF patients experienced problems in carrying out routines, 71.4% (Yogyakarta) and 50% (Bantul), respectively. Adult DHF patients in both hospitals reported pain and discomfort of 66.7% (Yogyakarta) and 100% (Bantul), respectively. The highest average medical costs paid by DF and DHF patients at PKU Jogja Hospital were IDR 4,919,450 and IDR 6,981,500. DF and DHF patients at PKU Hospital with BPJS insurance, with the highest average medical costs of IDR 2,726,245.5 (for DF patients) and IDR 4,797,700 (for DHF patients) to cover for laboratory costs.Conclusion: Dengue fever infections are impacting the patient's quality of life and medical costs.
Evaluation of Standard Procedures Operational in Tabanan District General Hospital: Usage of Special Control Antimicrobials (Restrictions) Noviyani, Rini; Putri, A. A. Sagung Indah Candra; Putri, Ni Wayan Prasanthi Swarna; Ekayanti, Ni Kd Rintan Listiani; Widatama, Agata
Jurnal Ilmiah Farmasi Vol. 20 No. 2 (2024): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol20.iss2.art2

Abstract

Background: The healthcare sector, specifically hospitals, is vulnerable to antimicrobial resistance due to diverse services and patient populations, alongside continuous intensive antimicrobial use. This resistance presents a significant national and global health threat. Therefore, implementing an antimicrobial stewardship program is crucial for reducing resistance development and spread in hospitals. Pharmacists, as healthcare professionals, have an essential role in upholding stewardship through pharmaceutical services in line with Standard Operating Procedure (SOP).Objective: This study aimed to evaluate Restricted Antimicrobial Standard Operating Procedure (SOP-A) at Tabanan Regional General Hospital (RSUD Tabanan) to enhance the quality of pharmaceutical services.Method: A qualitative method was used in SOP evaluation, comparing data from interviews with the Head of Pharmacy Installation at RSUD Tabanan and observations of implementation. The data were then contrasted with recent literature and regulations to identify discrepancies necessitating improvements. Moreover, data were analyzed using the descriptive method and presented in narrative, figure, and table formats.Results: The results showed that based on interviews and observations of SOP-A implementation, several revisions were needed. These revisions include adding restricted antimicrobials from the reserve categories (cefepime, cefpirome, and carbapenems), establishing a protocol for eligible patients without waiting for culture results, outlining a process for obtaining approval from the Head of the Antimicrobial Resistance Control Program (PPRA) and Hospital Director, as well as incorporating antimicrobial usage history into the restricted antibiotic use application form.Conclusion: SOP-A at RSUD Tabanan requires four key additions, namely a list of reserve category antimicrobials, a protocol for administering restricted antimicrobials to eligible patients without waiting for culture results, a process for obtaining approval from the Head of the PPRA and Hospital Director, as well as inclusion of antimicrobial usage history in the restricted antibiotic use application form.

Page 23 of 27 | Total Record : 269

 21   22   23   24   25 

Filter by Year

2004 2025


Reset
Filter By Issues
All Issue Vol. 21 No. 2 (2025): Jurnal Ilmiah Farmasi Vol. 21 No. 1 (2025): Jurnal Ilmiah Farmasi Vol. 20 No. 2 (2024): Jurnal Ilmiah Farmasi Vol. 20 No. 1 (2024): Jurnal Ilmiah Farmasi Vol. 19 No. 2 (2023): Jurnal Ilmiah Farmasi Vol. 19 No. 1 (2023): Jurnal Ilmiah Farmasi 2023: Special Issue Vol. 18 No. 2 (2022): Jurnal Ilmiah Farmasi Vol. 18 No. 1 (2022): Jurnal Ilmiah Farmasi 2022: Special Issue Vol. 17 No. 2 (2021): Jurnal Ilmiah Farmasi Vol. 17 No. 1 (2021): Jurnal Ilmiah Farmasi Vol. 16 No. 2 (2020): Jurnal Ilmiah Farmasi Vol. 16 No. 1 (2020): Jurnal Ilmiah Farmasi Vol. 15 No. 2 (2019): Jurnal Ilmiah Farmasi Vol. 15 No. 1 (2019): Jurnal Ilmiah Farmasi Vol. 14 No. 2 (2018): Jurnal Ilmiah Farmasi Vol. 14 No. 1 (2018): Jurnal Ilmiah Farmasi Vol. 13 No. 2 (2017): Jurnal Ilmiah Farmasi Vol. 13 No. 1 (2017): Jurnal Ilmiah Farmasi Vol. 12 No. 2 (2016): Jurnal Ilmiah Farmasi Vol. 12 No. 1 (2016): Jurnal Ilmiah Farmasi Vol. 11 No. 2 (2015): Jurnal Ilmiah Farmasi Vol. 11 No. 1 (2015): Jurnal Ilmiah Farmasi Vol. 10 No. 2 (2013): Jurnal Ilmiah Farmasi Vol. 10 No. 1 (2013): Jurnal Ilmiah Farmasi Vol. 9 No. 2 (2012): Jurnal Ilmiah Farmasi Vol. 9 No. 1 (2012): Jurnal Ilmiah Farmasi Vol. 8 No. 2 (2011) Vol. 7 No. 1 (2010) Vol. 6 No. 1 (2009) Vol. 5 No. 1 (2008) Vol. 4 No. 2 (2007) Vol. 4 No. 1 (2007) Vol. 3 No. 1 (2006) Vol. 2 No. 2 (2005) Vol. 2 No. 1 (2005) Vol. 1 No. 2 (2004) Vol. 1 No. 1 (2004) More Issue