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Majalah Obstetri dan Ginekologi
Published by Universitas Airlangga
ISSN : 08540381     EISSN : 25981013     DOI : 10.20473/mog.V27I32019.90-93
Core Subject : Health,
Health Professions Medicine & Pharmacology
Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology Association (POGI) of Surabaya branch.
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Articles 298 Documents
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Kartu Skor Poedji Rochyati in the Indonesian Maternal Referral System Sihotang, Jojor; Hidayatullah, Amiruddin
Majalah Obstetri & Ginekologi Vol. 32 No. 1 (2024): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I12024.44-53

Abstract

HIGHLIGHTS 1. This review focuses on maximizing the effectiveness of "Kartu Skor Poedji Rochyati" (KSPR) in Indonesia's maternal referral system.2. It addresses the lack of information about Indonesia's maternal referral system, offering valuable insights.3. Underlining the high rates of maternal and fetal deaths due to referral errors, the article stresses the urgency of understanding KSPR's function for high-risk pregnant women.   ABSTRACT Maternal Mortality Rate (MMR) represents fatalities during pregnancy, childbirth, and the postpartum period due to complications, not external factors. Timely detection is crucial for preventing maternal deaths, necessitating integrated planning. The "Kartu Skor Poedji Rochjati" (KSPR) emerges as a vital tool for identifying high-risk pregnancies, facilitating urgent referrals to mitigate complications and enhance healthcare. A literature review on maternal mortality, risk assessment tools, and KSPR effectiveness was conducted to address the issues. The findings are expected to highlight KSPR's pivotal role in identifying at-risk pregnant women, enabling prompt referrals, and reducing maternal mortality rates. The case studies and data analysis will enrich our understanding of the tool's impact on maternal healthcare. The apex of public health involves embracing health-conscious lifestyles, reflected in indicators like mortality and morbidity. Proactively identifying high-risk pregnancies using KSPR is a strategic step in averting maternal mortality. Leveraging KSPR allows early intervention, reducing complications and contributing to enhanced maternal health, aligning with the goal of minimizing mortality risks.
Incidence of radiation proctitis in cervical cancer receiving radiation therapy at Dr. Kariadi Hospital, Semarang, Indonesia Mirza Iskandar, Teuku; Kristiawan, Endy Cahyono; Faizal, Teuku Rendiza; Ambari, Ediwibowo; Putra, Very Great Eka; Achmad, Lubena
Majalah Obstetri & Ginekologi Vol. 31 No. 3 (2023): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V31I32023.123-128

Abstract

HIGHLIGHTS Radiation proctitis is a post-radiotherapy concern, urging research to reduce its occurrence and improve the well-being of patients. Radiotherapy is the primary treatment for advanced cervical cancer, offering hope and preserving quality of life for patients.   ABSTRACT Objective: To determine the incidence of radiation proctitis in cervical cancer patients after radiation at Dr. Kariadi Hospital, Semarang, Indonesia. Materials and Methods: A descriptive analytic study on 356 cervical cancer patients who received radiation therapy at Dr. Kariadi Hospital Semarang from January 2017 to December 2018 who met the inclusion criteria. Factors assessed included age, BMI, hematologic, stage, histopathology, history of radical hysterectomy surgery and duration of radiation. Cervical cancer staging was assessed using FIGO 2018. Statistical analysis was performed using Mann Whitney with a significant value of p <0.05. Results: From the Chi-square analysis, the relationship between radiation period (less than 56 days and more than 56 days)  (p=0.164), the relationship between age ≥45 and the incidence of proctitis (p=0.208), BMI ≥25 and the incidence of proctitis (p=0.838), Hb <10 with the incidence of proctitis (p=0.492), parity ≤1 with the incidence of proctitis (p=0.137), the relationship between the histopathological examination results with the incidence of proctitis (p=0.253), and stage level with the incidence of proctitis (p=0.226) were not significant. The highest incidence of proctitis occurred in stage 3B of the cervical cancer patients (14.5%). Conclusion: The prevalence of proctitis in cervical cancer patients for the period 2017-2018 was 15.4%. Age, histopathological appearance, stage, history of anemia, history of radical surgery and appearance of symptoms after surgery with symptoms of proctitis did not show a significant relationship.
The use of N-acetylcysteine to prevent further progression of preeclampsia Indrawan, I Wayan Agung; Farida, Leny
Majalah Obstetri & Ginekologi Vol. 32 No. 2 (2024): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I22024.106-111

Abstract

HIGHLIGHTS 1. The generation of free radicals in the placenta leads to endothelial dysfunction, which contributes greatly in preeclampsia.2. N-acetylcysteine have a role in the oxidative stress pathway, helping in glutathione synthesis and as a free radical scavenger.3. N-Acetylcysteine supplementation in women with preexisting preeclampsia had positive effects on oxidative stress biomarkers, laboratory values, and blood pressure.   ABSTRACT Objectives: Preeclampsia is a prevalent disorder among pregnant women, characterized by hypertension and proteinuria, leading to serious complications. However, the precise pathophysiology of preeclampsia remains debated. Oxidative stress is believed to play a significant role in its development, and N-acetylcysteine (NAC) is known to influence this pathway. NAC aids in glutathione synthesis, a critical antioxidant, and acts as a free radical scavenger. This study aimed to examine the role of NAC in women with preeclampsia, focusing on its potential therapeutic benefits. Materials and Methods: A comprehensive literature search was conducted using PubMed and ScienceDirect databases, yielding 17 articles from PubMed and 395 articles from ScienceDirect. Reviews were excluded, resulting in 12 articles from PubMed and 89 articles from ScienceDirect. After further screening, 5 articles were selected for review, including 2 human studies and 3 animal studies, to understand the impact of NAC on preeclampsia. Results: Human studies indicated that NAC supplementation reduced the rate of preeclampsia among women at increased risk. Animal studies supported these findings, showing improvements in oxidative stress biomarkers, laboratory values, and blood pressure in models treated with NAC. NAC supplementation was associated with positive outcomes in managing oxidative stress, a key factor in the pathogenesis of preeclampsia. Conclusion: NAC supplementation in women with preexisting preeclampsia has beneficial effects on oxidative stress biomarkers, laboratory values, and blood pressure. These highlight the potential of NAC as a therapeutic intervention for preeclampsia, particularly in women at high risk. However, no significant differences were observed in maternal complication rate between the NAC-treated group and the control group. Further research is needed to fully understand the clinical implications of NAC supplementation and its long-term safety and efficacy in managing preeclampsia.
Moringa oleifera extract affects the diameter of the Graafian follicles in female Mus musculus Amiruddin; Herman, Sriyana; Balumbi, Musthamin; Rahawarat, Marwia; Darlian, Lili; Fitrianingsih, Julia; Handayani, Rika; Rusli
Majalah Obstetri & Ginekologi Vol. 32 No. 1 (2024): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I12024.14-21

Abstract

HIGHLIGHTS This study unveils a dose-dependent relationship between Moringa leaf extract and increased Graafian follicle size in female mice. The significant positive effect of Moringa leaf extract on Graafian follicles suggests promising implications for fertility interventions, offering hope for individuals seeking natural treatment to address infertility challenges.   ABSTRACT Objective: This study aimed to determine the effect of Moringa leaf extract (Moringa oleifera Lam.) on the diameter of Graafian follicles in female mice (Mus musculus). Materials and Methods: This study used experimental design, employing a cohort of 24 female mice of 20-25 grams in weight, aged between 2-3 months, and in good health. These subjects were divided into three treatment groups and subjected to oral doses of Moringa leaf extract at 300 mg/kg BW, 400 mg/kg BW, and 500 mg/kg BW over a 14-day period. The study procedures involved the preparation of the experimental animals, preparation of Moringa leaf extract, treatments administration, and the preparation of histological specimens. Subsequently, the diameters of Graafian follicles within each treatment group were measured. Data analysis were performed using the ANOVA test (p <0.05) followed with the Least Significance Difference (LSD) test utilizing the IBM SPSS software. Results: There were variations in Graafian follicle diameters across the experimental groups. The average diameters were 180.944 µm in the control group, 239.942 µm in treatment group 1, 315.006 µm in treatment group 2, and 396.650 µm in treatment group 3. This indicated that dose administration starting from 300 mg/kg, 400 mg/kg, and 500 mg/kg had an effect on the size of the follicle and antrum diameter. The number of granulosa cells was found to increase, as well as the size of the ovum. Conclusion: Moringa leaf extract in different doses has a significant positive effect on increasing the diameter of the Graafian follicles in female mice.
Evaluation and diagnostic approach in patient with Perrault Syndrome Nathania, Rachael Christin; Usman, Steven Yulius; Aryasatiani, Ekarini
Majalah Obstetri & Ginekologi Vol. 32 No. 2 (2024): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I22024.143-147

Abstract

HIGHLIGHTS 1. The rare hereditary condition Perrault Syndrome is characterized by sensorineural hearing loss (SNHL) and ovarian dysfunction2. Cyclic estrogens and progesterone may be given to adolescents with amenorrhea to induce withdrawal bleeding and mimic the menstrual cycle.   ABSTRACT Objectives: A multidisciplinary team, which included a reproductive endocrinologist and an otolaryngologist, identified Perrault Syndrome in a patient with secondary amenorrhea and bilateral sensorineural hearing loss. Case Report: A 16-year-old female presented to the obstetrics and gynecology clinic at a type B hospital with primary amenorrhea for one year. Menarche occurred at age 13, followed by regular menstrual cycles for two years, after which menstruation gradually ceased. She denied dysmenorrhea, constipation, leukorrhea, genital pruritus, growth retardation, and weight loss. The patient expressed concern about potential future infertility. At age 9, she was diagnosed with a viral infection by an ENT specialist due to bilateral hearing loss, leading to emotional disturbances. There was no history of prior medication, family illness, or chronic infections. Born at term via spontaneous vaginal delivery, the patient weighed 3,000 grams. Laboratory tests revealed normal T3 (1.51 ng/dl), FT4 (1.16 ng/dl), prolactin (18.25 ng/ml), estrogen (11 pg/ml), and progesterone (0.1 pg/ml) levels, but elevated FSH (66.46 mIU/ml) and LH (29.97 mIU/ml) levels. Symptomatic treatment included bone conduction hearing aids and estrogen replacement therapy. Conclusion: Perrault Syndrome, a rare hereditary condition, manifests as sensorineural hearing loss (SNHL) and ovarian dysfunction, including primary ovarian insufficiency (POI) and gonadal dysgenesis, in individuals with a 46, XX karyotype. Molecular diagnosis remains challenging. Consultation with a pediatric endocrinologist can guide cyclic estrogen and progesterone therapy to induce withdrawal bleeding in adolescents with amenorrhea. Women at risk of ovarian failure should consider donor eggs or oocyte cryopreservation. Avoiding aminoglycosides and excessive noise is crucial for managing hearing loss.
The influence of patriarchal cultural factors on pregnancy complications (antepartum hemorrhage) at Mitra Medika General Hospital, Bandar Klippa, Indonesia Simamora, Liyana; Ismah, Zata; Susilawati
Majalah Obstetri & Ginekologi Vol. 32 No. 2 (2024): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I22024.89-96

Abstract

HIGHLIGHTS 1. Antepartum hemorrhage stands as one of the major contributors to maternal mortality globally. 2. Patriarchal culture is among the societal factors impacting maternal mortality rates.3. Patriarchal cultural factors associated with antepartum hemorrhage are examined to establish effective preventive measures.   ABSTRACT Objectives: The objective of this study was to determine the influence of patriarchal culture on the occurrence of antepartum hemorrhage at Mitra Medika General Hospital. Materials and Methods: This study employed an analytical observational design with a case-control approach. The sample for this study included pregnant women in their third trimester and mothers who had given birth within a maximum of 4 months from the time of the study at Mitra Medika General Hospital, Bandar Klippa, Indonesia. There were 90 respondents, comprising 30 case groups and 60 control groups. The sampling method for the case group used quota sampling, while the control group utilized accidental sampling. The research instrument utilized questionnaires and secondary data (antepartum hemorrhage diagnoses). Data analysis employed the chi-square test for bivariate analysis and multiple logistic regression for multivariate analysis, with a significance level of 0.05. Results: There was a significant relationship between decision-making (p=0.030), family support (p=0.003), psychological domestic violence (p=0.024), and sexual domestic violence (p=0.039), no relationship with physical domestic violence (p=0.257) with the occurrence of antepartum hemorrhage. Multivariate analysis revealed that the family support variable was the most dominant risk factor with an Exp (B) value of 8.230 in causing antepartum hemorrhage. Conclusion: The patriarchal cultural factors that significantly affect antepartum hemorrhage at Mitra Medika General Hospital, Bandar Klippa, Indonesia, are decision-making, family support, psychological domestic violence, and sexual domestic violence.
A case of vaginal varicosities without rupture after vaginal delivery Tandiono, Eunike Jennifer; Aryasatiani, Ekarini; Santoso, Brigita Naomi
Majalah Obstetri & Ginekologi Vol. 32 No. 1 (2024): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I12024.54-59

Abstract

HIGHLIGHTS Vaginal varicosities are prone to happen in pregnant women with unspecific causes and multifactorial. The mode of delivery in a pregnant woman with vaginal varicosities is still unknown, but it is not an indication of caesarean section.   ABSTRACT Objective: Vaginal varicose is a rare condition characterized by dilated veins in the labia majora, labia minora, and vagina. This case report reported a woman with vaginal varicose who experienced labor without any delivery complications. Case Report: The patient, a 29-year-old woman, gravida 3, para 2, presented with discomfort and swelling in the vagina at 32 weeks of gestational age. Despite reaching 39 weeks of gestation, the vaginal varicosities remained stable and painless. She had no prior history of varicose veins, hypertension, blood abnormalities, malignancy, or contraception usage. Physical examination revealed mild varicosities in the labium and significantly swollen varicosities protruding toward the vaginal introitus. Interestingly, a small varicose vein was also noted on her right leg, previously unnoticed by the patient. At 39 weeks pregnant, she experienced spontaneous vaginal delivery without complications. During the third stage of labor, the vaginal varicosities decreased in size, and no rupture occurred. The newborn, a healthy baby boy weighing 2961 grams and measuring 48 cm, was delivered vaginally. Despite a second-degree perineal tear, blood loss was minimal, and no complications nor rupture arose from the varicose veins. Conclusion: Vaginal varicosities are rare, primarily occurring in multigravida pregnant women between 12 and 26 weeks of gestation. This case highlights that cesarean section is not necessarily indicated in pregnant women with vaginal varicosities. The successful vaginal delivery in this instance resulted in no varicose vein rupture, controlled bleeding, and regression of vaginal varicosities postpartum.
Left hemiparesis due to space-occupying lesion in pregnancy Luminto; Aryasatiani, Ekarini; Panuntun, Mahendro Aji; Hassan, Bobby Wirawan; Sananta, Tania; Neil, Arya Elbert
Majalah Obstetri & Ginekologi Vol. 32 No. 2 (2024): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I22024.136-142

Abstract

HIGHLIGHTS 1. Present a case report detailing the diagnosis and management of a space-occupying lesion identified late in pregnancy.2. Current studies consistently indicate that the optimal period for tumor removal during pregnancy is the second trimester, balancing maternal and fetal outcomes. This case report contributes to the existing literature by providing a practical reference for managing space-occupying lesions in accordance with the latest evidence.   ABSTRACT Objectives: The objective of this study was to present the findings from cases of space-occupying lesions (SOL) that were diagnosed late in pregnancy. This case report aimed to highlight the importance of considering space-occupying lesions as a differential diagnosis in instances of hemiparesis during pregnancy, thereby raising clinical awareness and improving diagnostic accuracy. Case Report: A female patient aged 30 years 34 weeks pregnant came with complaints of slurred speech since 3 months before entering the hospital accompanied by weakness in the left limbs since 3 months before admission. The patient felt weak and fell in the bathroom 2 times, at the office and at home. The patient had a history of taking aspilet for 1.5 months due to a misdiagnosis as a stroke in a Type B hospital and stopped when she came to the obstetric emergency room at a Type A Hospital for the first time. Cardiothoracograph examination shows a picture of a silent baby. Computed Tomography (CT) Scan examination showed a picture of hydrocephalus. Conclusion: To date, it has not been proven that pregnancy triggers brain tumors. However, increased blood supply to the brain during pregnancy may lead to tumor growth. This is also evident in this case where there is an increase in maternal blood volume and subsequent cerebral blood flow, causing an increase in the size of the SOL. On the other hand, there is no evident that brain tumors directly harm the fetus, though fetal hypoxia may occur indirectly due to maternal respiratory failure.
Early diagnosis and appropriate management of vaginal leiomyoma in rural areas Nizomy, Ihya Ridlo; Budinurdjaja, Pribakti; Armanza, Ferry; Yuseran, Hariadi; Joyce; Lahdimawan, Inas Tsurayya Fauziah
Majalah Obstetri & Ginekologi Vol. 32 No. 1 (2024): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I12024.60-67

Abstract

HIGHLIGHTS Extrauterine leiomyoma, including vaginal leiomyoma, is an exceedingly rare condition with complex pathogenesis and management. Clinical evaluation and high-quality imaging are required to confirm the diagnosis of vaginal tumor. If there are insufficient facilities, referrals must be made. Operative management using vaginal approach was described for treating vaginal leiomyoma.   ABSTRACT Objective: To describe the challenges of early diagnosis and appropriate management of vaginal leiomyoma in rural areas. Case Report: A 26-year-old woman, P1A0, was referred from a rural hospital and presented a chief complaint of vaginal mass. The patient was admitted to the tertiary hospital with suspected malignant vaginal tumor and underwent a biopsy, which revealed leiomyoma on pathological examination. Despite conservative treatment, the mass continued to grow, unaffected by the menstrual cycle, causing discomfort. Following a second hospital admission, the patient underwent surgical management of extirpation and vaginal reconstruction. The microscopic finding of the tumor showed myositis cell proliferation with hyperplastic growth, monotonous nuclei, and variable cell shapes, supporting the diagnosis of vaginal leiomyoma. During postoperative monitoring, there was no vaginal bleeding. Thereafter, on the day following surgery, it was found that the right labium major was swollen. This was treated with anticoagulants, topical NSAIDs, and a sitz bath. The patient was discharged from the hospital in good condition and had an uneventful postoperative recovery. Conclusion: Although the incidence of vaginal leiomyoma is uncommon, precise early diagnosis and appropriate management might improve outcomes, particularly in rural areas.
The promise and challenges of Artificial Intelligence-Large Language Models (AI-LLMs) in obstetric and gynecology Gumilar, Khanisyah Erza; Tan, Ming
Majalah Obstetri & Ginekologi Vol. 32 No. 2 (2024): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I22024.128-135

Abstract

HIGHLIGHTS 1. The article highlights how Artificial Intelligence with Large Language Models (AI-LLMs) greatly improves diagnosis and treatment personalization in obstetrics & gynecology, and also enhances medical education through interactive simulations and up-to-date learning materials.2. The article also discusses the ethical issues linked to AI, emphasizing the need for cooperation among different stakeholders to use AI responsibly in medicine, focusing on protecting data privacy and minimizing reliance on technology.   ABSTRACT The introduction of Artificial Intelligence through Large Language Models (AI-LLM) into medicine holds great promise for improving patient care and medical education, especially in obstetrics and gynecology. AI-LLM can significantly improve diagnostic accuracy and treatment efficiency by utilizing large medical databases, which is especially useful for dealing with rare diseases that are difficult to document or understand by human practitioners alone. In addition, AI-LLM can provide informed patient care recommendations by analyzing large amounts of data and providing insights based on unique patient profiles, with the added benefit of being accessible 24/7 via the internet. This constant availability ensures that patients receive prompt information and assistance as needed. In the field of education, AI-LLMs enhance the learning experience by incorporating interactive simulations into the curriculum, improving medical students' and professionals' practical knowledge. They also ensure that educational materials are always up-to-date reflecting the most recent research and worldwide medical standards. This access latest information from global resources helps to bridge the educational gap, making advanced knowledge more accessible to learners regardless of their geographic location. However, the introduction of AI-LLMs is not without challenges. Ethical issues, such as data privacy and the risk of overreliance on technology, must be addressed. Effective management of these concerns necessitates collaboration among medical professionals, technological experts, academics, hospital committees, and representatives of patients. This multidisciplinary teamwork is vital for upholding ethical norms and preserving patient dignity and respect. AI-LLMs can considerably improve both patient care and medical education in obstetrics and gynecology provided they are appropriately balanced with innovation and ethics.

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