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All Journal Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ Best Journal (Biology Education, Sains and Technology) Indonesian Journal of Health Science Sehat Rakyat: Jurnal Kesehatan Masyarakat PubHealth Jurnal Kesehatan Masyarakat Health Research Journal of Indonesia Jurnal Ventilator: Jurnal Riset Ilmu Kesehatan dan Keperawatan
Putri Mulia
Universitas Bengkulu
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Determination of total alkaloid content in 70% and 96% ethanol extracts of red seaweed (Eucheuma spinosum) obtained by maceration using UV-Vis spect Sindi Arlin Natasya; Dwi Kurnia Putri; Rose Intan Perma Sari; Samwilson Slamet; Putri Mulia; Nurfitriyana Nurfitriyana
Indonesian Journal of Health Science Vol 6 No 3 (2026)
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v6i3.2261

Abstract

Red seaweed (Eucheuma spinosum) is one of the marine biological resources containing various secondary metabolites, including alkaloids which possess important biological activities. Differences in ethanol concentration may affect the amount of alkaloid compounds extracted. This study aimed to compare the alkaloid content of 70% ethanol extract and 96% ethanol extract of red seaweed (Eucheuma spinosum) obtained by maceration using the UV-Visible spectrophotometric method. This research was conducted experimentally in the laboratory using the maceration extraction method with 70% and 96% ethanol solvents. Qualitative identification of alkaloids was performed using Mayer, Wagner, and Dragendorff reagents, while quantitative determination was carried out using UV-Visible spectrophotometry with caffeine as the standard at a maximum wavelength of 275 nm. Phytochemical screening results indicated that both 70% and 96% ethanol extracts were positive for alkaloid compounds. The extraction yield of the 70% ethanol extract was 22.945%, whereas the 96% ethanol extract yielded 12.45%. The results of alkaloid determination showed that the 70% ethanol extract contained an average alkaloid level of 5.5 ± 0.22 mg QCE/g, while the 96% ethanol extract contained 5.3 ± 0.10 mg QCE/g. It can be concluded that the 70% ethanol extract produced a slightly higher alkaloid content than the 96% ethanol extract of red seaweed (Eucheuma spinosum).
Hubungan Pengetahuan dengan Sikap Masyarakat pada Penggunaan Antibiotik di Kelurahan Bumi Ayu Kota Bengkulu Defi Suryanti; Oky Hermansyah; Putri Mulia; Tri Danang Kurniawan; Dwi Dominica
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 5 No. 3 (2026): Agustus 2026
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v5i3.7554

Abstract

Irrational use of antibiotics in the community remains a health problem that can increase the risk of antimicrobial resistance, Low levels of public knowledge are suspected to influence the formation of inappropriate attitudes toward antibiotic use. This study aimed to analyze the relationship between the level of knowledge and community attitudes toward antibiotic use in Bumi Ayu Village, Bengkulu City. This study used a quantitative method with an observational analytic design through a cross-sectional approach. The sample consisted of 110 respondents selected using a proportional cluster random sampling technique. Data were collected using questionnaires that had been tested for validity and reliability, with Cronbach’s Alpha values of 0.702 for the knowledge variable and 0.786 for the attitude variable. Data were analyzed using univariate and bivariate analyses with the Chi-Square test. The results showed that most respondents had low knowledge levels, with 50 respondents (45.5%), and poor attitudes, with 50 respondents (45.5%). The bivariate analysis showed a significant relationship between the level of knowledge and community attitudes toward antibiotic use, with a p-value of 0.000 (p < 0.05). Respondents with better knowledge tended to have better attitudes toward antibiotic use. Therefore, continuous health education through health workers and information media is needed to improve public understanding of rational antibiotic use in order to prevent antimicrobial resistance.
FORMULASI DAN UJI EFEKTIVITAS ANTI NYAMUK MAT ELEKTRIK EKSTRAK ETANOL 96% KULIT BUAH DURIAN (Durio Zibenthinus L.): FORMULASI DAN UJI EFEKTIVITAS ANTI NYAMUK MAT ELEKTRIK EKSTRAK ETANOL 96% KULIT BUAH DURIAN (Durio Zibenthinus L.) Rose Intan Perma Sari Rose; Havis Arya Perdana; Suci Rahmawati; Dwi Kurnia Putri; Putri Mulia
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 8 No. 1 (2025)
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pmj.v8i1.61363

Abstract

ABSTRACT The composition of electric mosquito repellent contains the active ingredient d-allethrin which is a group of pyrethroids, metofluthrin, cyphenothrin which are very dangerous for health if used for a long period of time. Durian skin extract is a natural insecticide that can be an alternative ingredient as a substitute for chemicals from mosquito repellent products. This study aims to formulate an electric mosquito repellent preparation and to determine the ability of the preparation as a repellent. The preparation is made in four formulas, namely, F0 (0%), F1 (25%), F2 (35%) and F3 (45%). The preparation was then tested for physical properties including organoleptic, water content, density, weight uniformity, burning time test and repellent effectiveness. The results showed that the preparation met the parameters for testing physical properties. The effectiveness test using 25 mosquitoes exposed for 1 hour to the electric mat mosquito repellent preparation at F0, F1 and F2 did not meet the effectiveness value as a repellent because it was <80%, while at F3 it met the effectiveness value as a repellent of 82.7%. Keywords: Durian Fruit Peel, Extract, Mosquito Repellent, Electric Mat ABSTRAK Komposisi anti nyamuk elektrik mengandung bahan aktif d-allethrin yang merupakan golongan dari pyrethroid, metoflutrin, sifenotrin yang sangat berbahaya bagi kesehatan tubuh apabila digunakan dalam jangka waktu yang panjang. Ekstrak kulit durian merupakan bahan insektisida alami yang bisa menjadi bahan alternatif sebagai pengganti bahan kimia dari produk pengusir nyamuk. Penelitian ini bertujuan untuk memformulasi sediaan anti nyamuk mat elektrik dan untuk mengetahui kemampuan sediaan sebagai repellent. Sediaan dibuat dalam empat formula yaitu, F0 (0%), F1 (25 %), F2 (35%) dan F3 (45 %). Sediaan kemudian dilakukan pengujian sifat fisik meliputi organoleptis, kadar air, kerapatan, keseragaman bobot, uji lama bakar dan efektivitas repellent. Hasil penelitian menunjukan bahwa sediaan memenuhi parameter pengujian sifat fisik. Uji efektivitas menggunakan 25 ekor nyamuk yang dipaparkan selama 1 jam pada sediaan anti nyamuk mat elektrik pada F0, F1 dan F2 tidak memenuhi nilai efektivitas sebagai repellent karena < 80%, sedangkan pada F3 memenuhi nilai efektivitas sebagai repellent 82,7%. Kata kunci: Kulit Buah Durian, Ekstrak, Anti Nyamuk, Elektrik Mat
Hubungan Pengetahuan dengan Sikap Masyarakat pada Penggunaan Antibiotik di Kelurahan Padang Harapan Kota Bengkulu Fadillah Fadillah; Oky Hermansyah; Tri Danang Kurniawan; Putri Mulia; Ikhsan Ikhsan
Jurnal Ventilator Vol. 4 No. 2 (2026): Juni : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i2.2453

Abstract

Antibiotics are chemical substances used to kill or inhibit the growth of bacteria that cause infections; therefore, their use must be appropriate and in accordance with medical indications. Irrational use of antibiotics can increase the risk of antibiotic resistance, which has become a global health problem. Public knowledge and attitudes play an important role in determining antibiotic use behavior. This study aimed to analyze the relationship between the level of knowledge and community attitudes toward antibiotic use in Padang Harapan Village. This study used a quantitative method with an observational analytic design through a cross-sectional approach. The sample consisted of 108 respondents selected using proportional sampling techniques. Data were collected using questionnaires that had been tested for validity and reliability. Data were analyzed using univariate and bivariate analyses with the Chi-Square test. The results showed that most respondents had good knowledge levels (78.7%) and positive attitudes toward antibiotic use (76.9%). Bivariate analysis showed a significant relationship between knowledge level and community attitudes with a p-value of 0.000 (p<0.05). Respondents with better knowledge tended to have more positive attitudes toward antibiotic use. This study indicates that continuous health education is needed to improve public understanding of rational antibiotic use and prevent antibiotic resistance. Therefore, healthcare workers have an important role in providing accurate information regarding antibiotic use in the community. Efforts to improve public knowledge are expected to support appropriate, safe, effective, and rational antibiotic use in accordance with healthcare recommendations.
Perbedaan Tingkat Pengetahuan Pasien tentang Diabetes Melitus Sebelum dan Sesudah Diberi Edukasi Video di Puskesmas Sawah Lebar Kota Bengkulu Dearis Fitria Marten; Oky Hermansyah; Rose Intan Perma Sari; Yona Harianti Putri; Putri Mulia
PubHealth Jurnal Kesehatan Masyarakat Vol. 5 No. 2 (2026): Edisi Oktober
Publisher : Ilmu Bersama Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56211/pubhealth.v5i2.2144

Abstract

Diabetes mellitus adalah penyakit kronis dengan prevalensi yang terus meningkat dan memerlukan penanganan jangka panjang. Pengetahuan pasien memegang peranan penting dalam keberhasilan pengendalian penyakit dan pencegahan komplikasi. Salah satu upaya untuk meningkatkan pengetahuan pasien adalah melalui pendidikan kesehatan menggunakan media video yang menarik dan mudah dipahami. Penelitian ini bertujuan untuk mengetahui perbedaan tingkat pengetahuan pasien tentang diabetes mellitus sebelum dan sesudah menerima pendidikan berbasis video di Puskesmas Sawah Lebar, Kota Bengkulu. Penelitian ini menggunakan metode kuantitatif dengan desain kuasi-eksperimental melalui pendekatan pra-tes dan pasca-tes. Sampel terdiri dari 68 responden yang dipilih menggunakan teknik purposive sampling. Data dikumpulkan melalui kuesioner yang diberikan sebelum dan sesudah intervensi pendidikan berbasis video. Analisis data dilakukan menggunakan Uji Wilcoxon Signed Ranks karena data tidak berdistribusi normal. Hasil penelitian menunjukkan bahwa sebelum intervensi, sebagian besar responden memiliki tingkat pengetahuan yang rendah (80.9%), sedangkan setelah intervensi, tingkat pengetahuan meningkat ke kategori baik (51.5%). Analisis statistik menunjukkan nilai p sebesar 0.001 (p<0.05), yang mengindikasikan adanya perbedaan yang signifikan. Dapat disimpulkan bahwa pendidikan berbasis video efektif dalam meningkatkan pengetahuan pasien mengenai diabetes mellitus.
Pengaruh Edukasi Berbasis Video terhadap Peningkatan Pengetahuan Pasien tentang Penyakit Hipertensi di Puskesmas Sukamerindu Kota Bengkulu Nabila Nabila; Oky Hermansyah; Rose Intan Perma Sari; Putri Mulia; Samwilson Slamet
PubHealth Jurnal Kesehatan Masyarakat Vol. 5 No. 2 (2026): Edisi Oktober
Publisher : Ilmu Bersama Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56211/pubhealth.v5i2.2145

Abstract

Hipertensi adalah penyakit kronis yang sering tidak terdeteksi (pembunuh diam-diam) dan dapat menyebabkan komplikasi serius. Rendahnya tingkat pengetahuan pasien merupakan faktor utama yang menyebabkan tekanan darah tidak terkontrol. Penelitian ini bertujuan untuk mengetahui perbedaan tingkat pengetahuan pasien tentang hipertensi sebelum dan sesudah pendidikan berbasis video di Puskesmas Sukamerindu, Kota Bengkulu. Penelitian ini menggunakan desain kuasi-eksperimental kuantitatif dengan pendekatan pra-tes dan pasca-tes. Sebanyak 62 responden dipilih melalui teknik sampling purposif. Pengumpulan data dilakukan dengan menggunakan kuesioner sebelum dan sesudah intervensi. Analisis data menggunakan uji Wilcoxon karena data tidak berdistribusi normal. Hasil menunjukkan bahwa sebelum intervensi, mayoritas responden memiliki pengetahuan yang buruk (54.8%), sedangkan setelah intervensi, persentasenya meningkat ke kategori baik (58.1%). Skor pengetahuan median meningkat dari 5.00 menjadi 8.00. Uji Wilcoxon menunjukkan nilai p sebesar 0.001 (p < 0.05), yang berarti terdapat perbedaan yang signifikan sebelum dan sesudah intervensi. Berdasarkan hasil penelitian, dapat disimpulkan bahwa pendidikan berbasis video memiliki pengaruh yang signifikan terhadap peningkatan pengetahuan pasien mengenai hipertensi. Media video dapat digunakan sebagai metode pendidikan yang efektif untuk meningkatkan pemahaman pasien dan mendukung pengelolaan hipertensi.
Co-Authors : Samwilson Slamet, : Samwilson Asbedta Anggraini Assyifa Ainalaysia Betta Nirwana Dearis Fitria Marten Defi Suryanti Deni Maryani Dessy Triana Dominica, Dwi Dwi Kurnia Putri Fadillah Fadillah Farid, Muchammad Guntur Saputra Havis Arya Perdana Hera Olani Jaya Ningsih Ikhsan Ikhsan Maria Eka Patri Y Mauliani Dwi Nathasyah Nabila Aulia Putri Nabila Nabila Nesa Romanda Sari Nuraisyah Fitri Lesti Nurfitriyana Nurfitriyana Oky Hermansyah Regina Anggun Pitri Rifa Rihadatul Aisy Riska Dea Ananda Risky Hadi Wibowo Rose Intan Perma Sari Rose Intan Perma Sari Rose Septi Wulandari Sindi Arlin Natasya Sipriyadi Suci Rahmawati Sutra Elvyanti Syahbananda Zulyan Palse Tiara Nisrina Fitri Tika Hardini Tri Danang Kurniawan Try Nafilah Nujjiah Vernonia Yora Saki Yona Harianti Putri