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All Journal Jurnal Ilmu Kedokteran dan Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) MAHESA : Malahayati Health Student Journal Wal'afiat Hospital Journal Jurnal Info Sains : Informatika dan Sains Action Research Literate (ARL) Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh WAL'AFIAT HOSPITAL JOURNAL Jurnal Kesehatan Holistik Jurnal Kesehatan
Jaya, Muhammad Alim
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Journal : Action Research Literate (ARL)

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Psychodynamic Features of Depressed Patients with Dependent Personality Disorder and Hypokalemia: a Case Report Jaya, Muhammad Alim; Syahrir, Andi Karlina
Action Research Literate Vol. 8 No. 9 (2024): Action Research Literate
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/arl.v8i9.1901

Abstract

Depression is one of the most common mental disorders in society. Depression is influenced by several factors, including the personality of the sufferer and the existence of a comorbid disease that aggravates the symptoms. Several previous studies have not clearly reported on the psychodynamic picture of depressed patients with dependent personality disorder accompanied by hypokalemia. The study aims to provide a psychodynamic picture of depressed patients with dependent personality disorder accompanied by hypokalemia. A man, 26 years old, an Indonesian citizen, came with the main complaint of feeling helpless to do anything that has been burdensome for the last 2 months. The complaint was felt to be aggravating after he started working as a private employee. The patient feels insecure in his ability to complete the work assigned to him and feels that he is looked down upon by his peers and superiors. Patients often miss the figure of their deceased father. In addition, the patient has suffered from hypokalemia since he was in high school and has taken potassium supplements until now. The symptoms of depression experienced by patients are aggravated by the presence of dependent personality disorders and hypokalemia suffered by patients. Dependent personality disorder lowers the patient's confidence, and hypokalemia aggravates the vegetative symptoms he experiences, such as body weakness, decreased appetite, and palpitations. Dependent personality disorder and hypokalemia are very influential in aggravating the clinical symptoms experienced by depressed patients
Pengaruh Anti-Depresan dari Formulasi Sediaan Inhalasi Ekstrak Daun Bandotan (Ageratum Conyzoides L.) pada Model Hewan Depresi Jaya, Muhammad Alim; Gayatri, Sri Wahyuni; Wijaya, Muhammad Fajrin; Pratama, Melanie Ajeng; Nurhikma, Nurhikma
Action Research Literate Vol. 9 No. 1 (2025): Action Research Literate
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/arl.v9i1.2583

Abstract

Depresi merupakan gangguan suasana hati paling banyak di masyarakat, yang ditandai dengan perasaan sedih yang menetap. Antidepresan merupakan farmakologi utama dalam penanganan gangguan depresi. Namun, antidepresan memiliki kerja yang cukup lama dan efek samping yang besar. Sehingga diperlukan alternatif obat dengan efek samping yang kurang dan lebih efektif. Ageratum conyzoides L. merupakan tanaman herbal yang memiliki aktivitas farmakologi. Selain itu, belum ada pemberian obat secara inhalasi pada pasien depresi. Padahal, sediaan inhalasi dapat membantu penggunaan obat menjadi mudah dan praktis. Untuk menginvestigasi pengaruh sediaan inhalasi dari Ageratum conyzoides L. dalam memperbaiki gejala depresi pada mus musculus. Mus musculus dibagi secara acak dalam 6 kelompok (n=4), yaitu: 1) kontrol normal; 2) kontrol negatif: pemberian chronic mild stress (CMS); 3) Kontrol positif: pemberian CMS + fluoxetine 0,05 mg/kgBB; 4) Perlakuan 1: pemberian CMS + ekstrak Ageratum conyzoides L. (150 mg/kgBB); 5) Perlakuan 2: pemberian CMS + ekstrak Ageratum conyzoides L. (250 mg/kgBB); 6) Perlakuan 3: pemberian CMS + ekstrak Ageratum conyzoides L. (350 mg/kgBB) selama 14 hari. Selanjutnya, Forced Swimming Test dilakukan untuk menilai pengaruh Ageratum conyzoides L. dalam memperbaiki gejala mirip depresi pada mus musculus. Tidak ditemukan perbedaan bermakna antara kelompok kontrol positif dengan perlakuan 1, 2, dan 3. Dan, kelompok perlakuan 2 memiliki kecenderungan lebih baik dibandingkan kelompok perlakuan lainnya dalam memperbaiki gejala mirip depresi. Ini menunjukkan kemungkinan potensi efek antidepresan dari ekstrak ini yang serupa dengan fluoxetine. Ageratum conyzoides L. memperbaiki gejala mirip depresi pada mus musculus dan mungkin memiliki mekanisme kerja yang mirip dengan fluoxetine.
Co-Authors Aisyah, Sahida Nur Amaliyah B, Ilma Khaerina Arifin, Arina Fathiyyah Assegaf, Nurul Asmaul Husnah Bakthiar, Ilma Kherina Amaliyah Balqis, Nur Huriyah Bamahry, Aryanti R. Dewi, Anna Sari Gani, Aziz Beru Gayatri, Sri Wahyuni Harahap, Wirawan Haris, Andi Jihan Nashila Hasbi, Berry Erida Herlina, Besse Ismail, Wirasto Japari, Agus Karim, Marzelina Luthfiani, Evy Muchsin, Achmad Harun Mulyadi, Farah Ekawati Musani, Melda Ayu Amanda Namirah, Hanna Aulia Nevi sulvita karsa Nilam, Nilam Nurhayati Nurhikma, Nurhikma Oktaviani, Mentari Dwi Pratama, Melanie Ajeng Puspita, Andi Adelia Rachmat Faisal Syamsu, Rachmat Faisal Sanusi, Mayamariska Sri Vitayani Swarga, Tirta Syahrir, Andi Karlina Tegar Perkasa, Tegar Utami, Dian Fahmi Wijaya, Muhammad Fajrin