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UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL BONGGOL BROKOLI (Brassica oleracea L. var. Italica) DENGAN METODE DPPH (1,1-Diphenyl-2-Picrylhydrazy) Umaya, Chindy; Marbun, Nova Rianti; Br Sembiring, Tio Ranti Sari
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2732

Broccoli (Brassica oleracea L. var. Italica) is a vegetable recognized for its abundant bioactive components, such as flavonoids, tannins, saponins, and vitamin C, which are linked to antioxidant capabilities. Notwithstanding its health advantages, the broccoli stalk is frequently disregarded and underexploited, despite its potential as a source of natural antioxidant chemicals. This work aims to assess the antioxidant activity of the ethanolic extract from broccoli stalks utilizing the DPPH method and to ascertain its IC₅₀ value. The extraction was conducted via the maceration method utilizing 70% ethanol, and the antioxidant activity was assessed through UV-Vis spectrophotometry at a peak wavelength of 516 nm. The results indicated that the ethanolic extract of broccoli stem possesses considerable antioxidant activity, with an IC₅₀ value of 35.74 µg/ml. The IC₅₀ value of vitamin C was shown to be 7.67 µg/ml. The results indicate that broccoli stalks may be a significant source of natural antioxidants. The validation of the analytical method demonstrated outstanding results, including linearity (r = 0.9989), accuracy (100.57%), and precision (%RSD = 0.5646%).

“UJI EFEKTIVITAS FORMULASI EKSTRAK ETANOL BUAH PARE (Momordica charantia L.) DENGAN DAUN PEPAYA (Carica Papaya L.) SEBAGAI LOTION AEDES AEGYPTI” SEMBIRING, TIO RANTI SARI; Simorangkir, Delisma Marsauli
Jurnal Penelitian Farmasi Dan Herbal Vol. 8 No. 1 (2025): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i1.2734

Flaviviridae, genus Flavivirus, and group of arthropod-borne viruses. Aedes mosquitoes, particularly Aedes aegypti or Aedes albopictus, are the primary vectors of dengue disease transmission. A product that is used in skin-protection cosmetics to protect the skin from mosquito bites is anti-mosquito lotion (repellent). Water, emulsifying agents, humectants, and fatty ingredients make up lotion preparations. The bitter gourd and papaya leaves employed in this study were the active ingredients used to make lotion preparations. The lotion formulation used in this investigation contained flavonoid chemicals at varied extract concentrations of 0%, 2%, 4%, and 6%. The bitter gourd's and leaves' active components Because papaya is known to contain a lot of antioxidants, it can be used as an insecticide and lotion to ward against mosquitoes. According to SNI-16-4399-1996, preparations for anti-mosquito lotion made from papaya leaves and bitter melon extract pass the physical quality test because they are all homogeneous, have an oil-in-water emulsion type, are stable during storage for two weeks, and do not irritate the skin. Anti-mosquito lotion made with bitter melon fruit extract and papaya leaves, which is distinguished by the presence of dead mosquitoes in each formulation, has an effect on the effectiveness as an insecticide or repellent against mosquitoes on the skin that is applied. The extract lotion preparations' concentration The most powerful insecticide or mosquito repellant is a 6% extract of bitter gourd fruit and papaya leaves.

FORMULASI SEDIAAN LILIN EKSTRAK MINYAK ATSIRI BUNGA SEDAP MALAM (Polianthes tuberosa ) SEBAGAI AROMATERAPI TIO RANTI SARI SEMBIRING; Evi Depiana
Jurnal Pengabdian Masyarakat Putri Hijau Vol. 6 No. 3 (2026): Jurnal Pengabdian Masyarakat Putri Hijau (JPMPH)
Publisher : INSTITUT KESEHATAN DELI HUSADA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpmph.v6i3.3096

This study aims to formulate and evaluate aromatherapy wax preparations from nightshade flower essential oil extract (Polianthes tuberosa) as an effort to handle non-pharmacological stress. The essential oil of the nightshade flower is obtained through the method of steam distillation from 10 kg of fresh flowers, resulting in 30 ml of essential oil. The characterization of simplicia showed a moisture content of 5.71%, a water soluble cider content of 17.13%, an ethanol soluble cider content of 18.01%, a total ash content of 10.82%, and an acid-insoluble ash content of 1.49%, meeting the requirements of the Indonesian Herbal Pharmacopoeia. Phytochemical screening identifies alkaloids, flavonoids, tannins, saponins, triterpenoids, and glycosides. Aromatherapy candles are formulated in four variations of essential oil concentrations (Polianthes tuberosa): 0% (F0), 5% (F1), 10% (F2), and 15% (F3), as well as one positive control (F4). Physical evaluation shows all formulas have a good, dense, and air bubble-free appearance. The hedonic test showed that the F3 formula (15% essential oil) was preferred by the panelists in terms of aroma, shape, and color, and provided a significant relaxation and refreshment effect, close to the quality of commercial products. The F3's burn time reaches 10 hours, showing good durability.

FORMULASI SEDIAAN LILIN EKSTRAK MINYAK ATSIRI BUNGA SEDAP MALAM (Polianthes tuberosa ) SEBAGAI AROMATERAPI Nova Rianti Marbun; Tio Ranti Sari Br Sembiring
Jurnal Penelitian Farmasi & Herbal Vol. 8 No. 2 (2026): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i2.2944

This study aims to formulate and evaluate aromatherapy wax preparations from nightshade flower essential oil extract (Polianthes tuberosa) as an effort to handle non-pharmacological stress. The essential oil of the nightshade flower is obtained through the method of steam distillation from 10 kg of fresh flowers, resulting in 30 ml of essential oil. The characterization of simplicia showed a moisture content of 5.71%, a water soluble cider content of 17.13%, an ethanol soluble cider content of 18.01%, a total ash content of 10.82%, and an acid-insoluble ash content of 1.49%, meeting the requirements of the Indonesian Herbal Pharmacopoeia. Phytochemical screening identifies alkaloids, flavonoids, tannins, saponins, triterpenoids, and glycosides. Aromatherapy candles are formulated in four variations of essential oil concentrations (Polianthes tuberosa): 0% (F0), 5% (F1), 10% (F2), and 15% (F3), as well as one positive control (F4). Physical evaluation shows all formulas have a good, dense, and air bubble-free appearance. The hedonic test showed that the F3 formula (15% essential oil) was preferred by the panelists in terms of aroma, shape, and color, and provided a significant relaxation and refreshment effect, close to the quality of commercial products. The F3's burn time reaches 10 hours, showing good durability.

PENETAPAN KADAR VITAMIN C PADA BROKOLI PUTIH (Brassica oleracea L.) YANG BEREDAR DI KECAMATAN DELI TUA DENGAN METODE SPEKTROFOTOMETRI UV-VIS Jhan Saberlan Purba; Tio Ranti Sari Br Sembiring
Jurnal Penelitian Farmasi & Herbal Vol. 8 No. 2 (2026): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i2.2946

White broccoli (Brassica oleracea L.) is a vegetable rich in vitamin C and has potential as a functional food source beneficial to health. This study aimed to determine the vitamin C content in white broccoli available in Deli Tua District using the UV-Vis spectrophotometric method and to evaluate the validity of the applied analytical method. The broccoli sample was extracted, analyzed qualitatively using iodine reagent, and quantitatively at a maximum wavelength of 265 nm. The calibration curve was constructed using five standard concentrations of vitamin C with a regression equation of y = 0.0495x + 0.0019 and a correlation coefficient r = 0.9996, indicating excellent linearity. The analysis showed that the vitamin C content was 1,8098 mg/g. The method validation met the required criteria: accuracy % recovery of 108.36%, precision RSD 0.47739%, limit of detection LOD of 0.18375, and limit of quantification LOQ of 0.61325. Therefore, the UV-Vis spectrophotometric method is proven valid and accurate for determining the vitamin C content in white broccoli.

FORMULASI EKSTRAK ETANOL BUAH PARE DAN DAUN PEPAYA SEBAGAI LOSION REPELAN Aedes aegypti Gratia Apulina Cindylawsa Purba; Delisma Marsauli Simorangkir; Tio Ranti Sari Br Sembiring; Putri Anggita
Jurnal Penelitian Farmasi & Herbal Vol. 8 No. 2 (2026): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i2.2949

Dengue Hemorrhagic Fever (DHF) is a disease caused by the dengue virus from the genus Flavivirus and the family Flaviviridae, transmitted through the bites of Aedes aegypti and Aedes albopictus. One preventive measure can be achieved by using mosquito repellent lotion as a protective topical preparation. Bitter melon and papaya leaves contain flavonoids and antioxidants that have potential as natural repellent agents. This study aimed to evaluate the effectiveness of lotion formulations containing bitter melon and papaya leaf extracts at concentrations of 0%, 2%, 4%, and 6%. The research method included preparing lotion formulations based on an oil-in-water emulsion, followed by physical quality testing according to SNI 16-4399-1996, including assessments of homogeneity, emulsion type, two-week stability, and skin irritation. Repellent effectiveness was tested by observing the number of mosquitoes that died after contacting skin treated with the lotion. The results show that all formulations meet the physical quality requirements, are homogeneous, stable, possess an oil-in-water emulsion type, and do not cause skin irritation. The extracts increase mosquito repellency, as indicated by the greater number of dead mosquitoes with higher extract concentrations. The 6% formulation is the most effective concentration as a repellent or insecticidal agent against Aedes aegypti.

UJI AKTIVITAS DEODORANT SPRAY EKSTRAK ETANOL DAUN KITOLOD (Isotoma longiflora (L.) C. Presl) TERHADAP BAKTERI Staphylococcus aureus Delisma Marsauli Simorangkir; Gratia Apulia CP Purba; Tio Ranti Sari Br Sembiring; Sardamai Laia Laia
Jurnal Penelitian Farmasi & Herbal Vol. 8 No. 2 (2026): Jurnal Penelitian Farmasi dan Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v8i2.2953

This study aims to determine the effectiveness of ethanol extract of cytolod leaves (Isotoma longiflora (L.) C. Presl) formulated in spray deodorant preparations as an antibacterial against Staphylococcus aureus. The extraction of cytolod leaves is carried out by the maceration method using 96% ethanol solvent. Spray deodorant preparations are made in three different extract concentrations, namely 3% (F1), 5% (F2), and 8% (F3), with positive control using commercial deodorant (AXE) and negative control in the form of a base preparation without extract. Antibacterial effectiveness testing was carried out using the suction diffusion method. The results of the physical evaluation showed that all formulas met the requirements of organoleptic, pH, clarity, viscosity, drying time, sprayability, and did not cause irritation to the skin. The results of the antibacterial activity test showed that the higher the concentration of the extract, the larger the barrier zone formed. Formulas with a concentration of 8% (F3) show the most effective inhibition activity with an average inhibition zone diameter of 15.73 mm, which belongs to the strong category.

Analisis Kualitatif dan Kuantitatif Formalin pada Bakso yang Dijual di Deli Tua Timur Gratia Apulina Cindylawsa; Delisma Marsauli Simorangkir; Tio Ranti Sari Sembiring
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 2 (2025): September 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i2.14334

Bakso merupakan salah satu produk olahan daging yang banyak digemari masyarakat. Dalam proses pembuatannya sering ditemukan penyalahgunaan bahan berbahaya salah satunya adalah formalin yang digunkan untuk memperpanjang daya simpan.produk. Formalin adalah larutan formaldehida dalam air yang bersifat toksik dan bukan termasuk bahan tambahan pangan (BTP) yang diizinkan penggunaannya dalam makanan. Penelitian ini bertujuan untuk menganalisis kandungan formalin pada bakso yang dijual di Deli Tua Timur. Sampel bakso diperoleh secara acak dari beberapa pedagang di wilayah tersebut. Penelitian ini dilakukan dengan metode kualitatif dengan uji warna menggunakan pereaksi KMnO4 dan metode kuantitatif menggunakan spektrofotometri UV-Vis yang diukur pada panjang gelombang 336 nm untuk formalin. Validasi metode yang dilakukan terhadap metode meliputi parameter akurasi, presisi, linearitas. batas deteksi, dan batas kuantifikasi. Hasil penelitian menunjukkan bahwa 3 dari 5 sampel memiliki hasil positif mengandung formalin berdasarkan uji kualitatif, dan analisis kuantitatif memperlihatkan kadar formalin pada bakso A 2,316 mg/g, bakso B 1,73891 mg/g, dan bakso C 1,15456 mg/g. Hasil uji validasi pada bakso A diperoleh persen recovery 98,38% dan simpangan baku relatif 0,29%, pada diperoleh persen recovery bakso B 101,43% dan simpangan baku relatif 0,41%, dan bakso C diperoleh persen recovery 106,13% dan simpangan baku relatif 0,90%. Semua parameter validasi berada dalam kisaran yang dapat diterima. Dapat disimpulkan bahwa masih terdapat penyalahgunaan formalin pada bakso yang beredar di Deli Tua Timur

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