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All Journal Jurnal Ilmu Kesehatan Masyarakat Jurnal NERS Indonesian Journal of Tropical and Infectious Disease Martabe : Jurnal Pengabdian Kepada Masyarakat Ensiklopedia of Journal Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Jurnal Menara Ekonomi : Penelitian dan Kajian Ilmiah Bidang Ekonomi Indonesian Journal of Global Health research Respiratory Science Narra J JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Pengabdian kepada Masyarakat Dewantara Asian Journal of Public Health and Nursing
Yanti, Budi
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Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : Narra J

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Giant bronchopleural fistula and empyema in a tuberculosis patient with diabetes mellitus: Vista from a high tuberculosis burden country in Southeast Asia Yanti, Budi; Hadi, Saiful; Harrika, Fenny; Shehzad, Aamir
Narra J Vol. 2 No. 2 (2022): August 2022
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v2i2.81

Abstract

Bronchopleural fistula is a pathological tract between the bronchial tree and the pleural space, which can be life-threatening due to tension pneumothorax. It is a rare complication in tuberculosis cases with highly variable in clinical manifestations and persistent air leaks which might lead to complications such as empyema. Herein, we present a tuberculosis and diabetic patient complicated with giant bronchopleural fistula and empyema. A 48-year-old man presented with shortness of breath for two weeks and cough with phlegm for two months. The patient was a smoker with severe Brinkman Index and diabetes. Physical examination revealed hyper resonant percussion and vesicular diminished on the left hemithorax. Laboratory results indicated the patient had anemia, leukocytosis, and hypoalbuminemia. GeneXpert sputum confirmed the presence of Mycobacterium tuberculosis and chest X-ray indicated a collapsed left lung. The patient was diagnosed with left secondary spontaneous pneumothorax, pulmonary tuberculosis, and diabetes. The patient was treated with chest tube drainage and anti-tuberculosis drugs. There was no improvement based on serial chest X-ray, and empyema appeared from the chest tube. CT-scan showed tuberculosis lesion, the collapsed of the left lung and fistula in segments 7-8 inferior lobe. Exploratory thoracostomy was performed, in which a giant bronchopleural fistula was detected and then repaired with BioGlue surgical adhesive. Unfortunately, the thoracostomy led to extensive subcutaneous emphysema and was treated by cervical mediastinotomy. The drainage was unable to be removed, and the patient was discharged with Heimlich-type drainage valves on day 28 of treatment. The empyema fluid was cultured and revealed Staphylococcus haemolyticus. This case highlights that tuberculosis could cause a bronchopleural fistula and empyema may occur secondary to late diagnosis that needs immediate surgery.
Risk factors of early mortality in COVID-19 patients in Indonesia: A retrospective cohort study in a provincial referral hospital of Aceh Ismayana, Vera; Yanti, Budi; Kurniawan, Ferry D.; Zulfikar, Teuku; Yusuf, Nurrahmah
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.185

Abstract

Some of coronavirus disease 2019 (COVID-19) patients died after being hospitalized and early mortality is a matter of concern during the pandemic; therefore, it is critical to determine which patients are the most vulnerable of having early mortality. The aim of this study was to determine the risk factors for early mortality among hospitalized COVID-19 patients in Indonesia. A retrospective cohort study was conducted on hospitalized COVID-19 patients from July 2020 to September 2021 at Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia. Demographic data, clinical characteristics, laboratory findings, and mortality were collected. Early mortality was defined as a death before seven days of the hospitalization. Multivariate regression analysis was employed to determine the risk factors associated with early mortality. We included the data of 624 COVID-19 patients who died during the study period. More than half of the patients were male and aged over 50 years old. The average hospitalization period was 10 days and most patients had more than two comorbidities. Chronic lung disease was the most common comorbidity (46.0%) followed by respiratory disease (26.8%) and heart disease (14.3%). Multiple comorbidities and elevated D-dimers exceeding 3376.92 ng/mL were associated with early mortality with OR: 7.029; 95%CI: 2.02–24.43 and OR: 1.000085, 95%CI: 1.000028–1.000142, respectively. In conclusion, early mortality in COVID-19 patients was associated with having multiple comorbidities and elevated D-dimer level. Therefore, it is crucial to assess the presence of comorbidities and routine laboratory test while managing COVID-19 patients in order to prevent the early mortality.
Co-Authors Afrina, Devi Agustika, Rudi Ariani, Fitri Asril, Aulia Rahma Azhar, Mulkan Azizi, Jamalul Bakhtiar Bakhtiar Desi Salwani, Desi Dewi Anggraini Dian Nurani Teo, Cut Dianova, Sri Duta, Teuku Fais Dwikornida, Dwikornida Febriansyah, TM. FIRDAUSA, SARAH Giawa, Natalius Hardisa, Rika Harrika, Fenny Hasan, Lenny Irmaini, Irmaini Irmayani Irmayani Irsyah, Abid Dhiyauddin Alfani Islami, Syaifuddin Ismayana, Vera Karunia, Yuris Hikman Khairiyyah, Yaumil Kurniawan, Ferry D. Kurniawan, Ferry Dwi Lenny Hasan, Henny Sjafitri, Nelharosma, Liza Salawati, Liza Maulana, Muhammad Iqbal Mekasari, Chelsy Mudinillah, Adam Muhamad, Zarfan Fawwaz Nauval, Iflan Nolasary, Mega Putri Novita Andayani, Novita Nurlina Nurlina Ossa, Yuli Fatzia Prihatin, Moliddina Priyanto, Herry Purqan, Muhammad Rachmi Merrina Rafindo, Hadi Saiful Hadi Seven, Yusmita Shehzad, Aamir Sherina Sherina, Sherina Siti Hajar Syamsiar, Syamsiar Teuku Heriansyah, Teuku Teuku Zulfikar Widodo Haryoko Yanifitri, Dewi Behtri Yonaldi, Sepris Yudas Sabaggalet Yunita Arliny Yunita Arliny Yusuf, Nurrahmah Zulfikar , T. Zulfikar, T