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Study of Antihypertensive and Antiplatelet Use in Outpatient Preeclampsia Patients at Siti Khodijah Sepanjang Hospital Purwanti, Uchti Firda; Fandinata, Selly Septi
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 16, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.98249

Abstract

Background: Preeclampsia is a complication of pregnancy characterized by increased blood pressure and the presence of proteinuria after reaching 20 weeks of gestation. Besides that, the diagnosis of preeclampsia can be reinforced by other symptoms such as edema, impaired liver and kidney function.Objectives: This study aims to investigate the usage of antihypertensive and antiplatelet medications in outpatient preeclampsia patients at Siti Khodijah Sepanjang Hospital from January 2022 to December 2023.Methods: Data collection method is retrospective, obtained from medical records of 70 preeclampsia patients. The sampling technique using purposive sampling method according to the inclusion research criteria. Data was analyzed using Microsoft Excel 2021.Results: Data on drug usage profiles obtained during the treatment, shows that the most common combination is a combination of two antihypertensive drugs and an antiplatelet, namely metildopa (category B) + aspirin (category C), with a dosage of 500 mg + 80 mg per day. The medication regimen is S2dd1 + S1dd1, and the average duration of treatment ranges from 7 to 30 days. With this treatment, the blood pressure of preeclampsia patients experienced a change in the patient's blood pressure which decreased in 65 patients with the initial classification of mild preeclampsia being 54 patients to normal in the final preeclampsia classification of 56 patientsConclusion: This study provides several important implications for health workers in Indonesia in the management of preeclampsia disease with the use of antihypertensive and antiplatelet drugs, so that they can provide services that are in accordance with the medical needs of patients.
Association of medication adherence with clinical outcomes and quality of life in type 2 diabetes mellitus patients: a cross-sectional study Fandinata, Selly Septi; Putra, Deddy Aryanda; Lubada, Eziah Ika; Sari, Silfiana Nisa Permata; Devientasari, Chinthia; Ernawati, Iin; Suryandari, Mercyska; Berliana, Dini
Media Penelitian dan Pengembangan Kesehatan Vol. 36 No. 1 (2026): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v36i1.2218

Abstract

Background: Type 2 diabetes mellitus is a chronic metabolic disorder characterized by elevated blood glucose levels. Patient adherence to medication is a critical factor in effective management, as it can reduce morbidity and mortality while improving health-related quality of life (HRQoL). Digital interventions, such as smartphone-based medication reminder applications, represent a promising strategy to enhance adherence. Objective: This study aimed to examine the relationship between medication adherence and clinical outcomes, specifically fasting blood glucose levels and HRQoL, among patients with type 2 diabetes in primary health care settings. Methods: A cross-sectional pre–post test design was employed involving 96 respondents, divided equally into control and intervention groups, selected through convenience sampling. Primary data were collected using the MARS-10 adherence questionnaire and the DQOL Brief Clinical Inventory, while secondary data were obtained from pre– and post–fasting blood glucose measurements. Results: Results showed no significant relationship between medication adherence and fasting blood glucose levels (p > 0.05), nor between adherence and HRQoL (p > 0.05), even with the implementation of the Drug Reminder App intervention. Conclusion: These findings highlight the need for additional interventions or further innovations in digital adherence support to improve clinical and quality-of-life outcomes in type 2 diabetes management.
Penguatan Branding Desa Wayut Berbasis Aset Budaya melalui Tradisi Sedekah Sayur Silfiana Nisa Permatasari; Kinanti Puji Lestari; Widya Dara; Fitria Abbas Thalib; Eziah Ika Lubada; Selly Septi Fandinata
Bangun Desa: Jurnal Pengabdian Masyarakat Vol. 5 No. 1 (2026)
Publisher : Universitas Alma Ata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/jbd.2026.5(1).1-12

Abstract

Abstrak Tradisi sedekah sayur merupakan salah satu aset budaya yang masih dilestarikan oleh masyarakat Desa Wayut dan memiliki potensi untuk mendukung penguatan identitas lokal desa. Kegiatan pengabdian kepada masyarakat ini bertujuan mengoptimalkan tradisi sedekah sayur sebagai aset budaya dalam upaya membangun branding Desa Wayut berbasis kearifan lokal. Kegiatan dilaksanakan di Dusun 2 Wayut, Kecamatan Jiwan, Kabupaten Madiun menggunakan pendekatan Asset-Based Community Development (ABCD) yang meliputi tahapan discovery, define, dream, design, dan destiny. Metode yang digunakan meliputi observasi, diskusi partisipatif, sosialisasi, dokumentasi, dan publikasi digital. Hasil kegiatan menunjukkan bahwa tradisi sedekah sayur berhasil diidentifikasi sebagai aset budaya yang berpotensi menjadi identitas lokal Desa Wayut. Partisipasi masyarakat meningkat melalui keterlibatan dalam donasi, pengemasan, distribusi, serta publikasi kegiatan melalui media sosial. Selain itu, tradisi berkembang dari sedekah sayur menjadi sedekah sayur dan sembako sebagai bentuk penguatan kepedulian sosial masyarakat. Luaran kegiatan berupa dokumentasi dan publikasi digital yang mendukung promosi budaya lokal serta branding Desa Wayut.   Abstract The vegetable alms tradition is a cultural asset still preserved by the Wayut Village community and has the potential to support the strengthening of the village's local identity. This community service activity aims to optimize the vegetable alms tradition as a cultural asset in an effort to build Wayut Village branding based on local wisdom. The activity was carried out in Wayut Hamlet 2, Jiwan District, Madiun Regency using an Asset-Based Community Development (ABCD) approach that includes the stages of discovery, define, dream, design, and destiny. The methods used included observation, participatory discussions, socialization, documentation, and digital publication. The results of the activity showed that the vegetable alms tradition was successfully identified as a cultural asset that has the potential to become the local identity of Wayut Village. Community participation increased through involvement in donations, packaging, distribution, and publication of activities through social media. In addition, the tradition evolved from vegetable alms to vegetable and basic food alms as a form of strengthening community social awareness. The output of the activity was documentation and digital publication that supported the promotion of local culture and the branding of Wayut Village.
Analysis of the Relationship Between HIV/AIDS Clinical Stage and Opportunistic Infections at Hospital X Chinthia Devientasari; Selly Septi Fandinata
Strada Journal of Pharmacy Vol. 8 No. 1 (2026): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v8i1.287

Abstract

Opportunistic infections remain a major cause of morbidity and mortality among people living with Human Immunodeficiency Virus (HIV). The progressive decline in immune function increases susceptibility to infections such as tuberculosis, candidiasis, and toxoplasmosis. The World Health Organization (WHO) clinical staging system is widely used to assess HIV disease progression and is often associated with the occurrence of opportunistic infections. This study aimed to analyze the association between HIV clinical stage and opportunistic infections among HIV/AIDS patients at Hospital X. This study employed an observational analytic design with a cross-sectional approach. Data were obtained from medical records of HIV/AIDS patients, with a total sample of 193 patients selected using total sampling. Statistical analyses included univariate and bivariate analyses using the chi-square test. The majority of patients were in clinical stage III (80.3%). The prevalence of opportunistic infections was 14.0%. The results of the chi-square test showed no significant association between clinical stage and opportunistic infections (p = 0.206). Although opportunistic infections were more frequently observed in advanced stages, the relationship was not statistically significant.
Peningkatan Pengetahuan Remaja tentang Penggunaan Bahan Alam dalam Mengatasi Asam Lambung Luluk Aniqoh Meliana Putri; Sri Rahayu Dwi Purnaningtyas; Selly Septi Fandinata; Dabyt Faizin Firzatullah; Varel Tsania Faza; Devita Riafinola Andaririt; Chinthia Devientasari; Ivan Junius Mesak
APMa Jurnal Pengabdian Masyarakat Vol. 6 No. 2: Juli 2026
Publisher : STIKES Bhakti Husada Mulia Madiun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47575/apma.v6i2.949

Abstract

Peningkatan kasus asam lambung pada remaja dipengaruhi oleh gaya hidup tidak sehat dan rendahnya pengetahuan mengenai pencegahan serta penanganannya, sehingga kegiatan ini bertujuan meningkatkan pemahaman remaja tentang penggunaan bahan alam dalam mengatasi asam lambung. Metode yang digunakan adalah edukasi melalui penyuluhan kesehatan kepada siswa SMA dengan media presentasi, brosur, serta evaluasi menggunakan pretest dan post-test. Hasil menunjukkan adanya peningkatan signifikan pengetahuan peserta dari rata-rata 65,15% menjadi 91,51% setelah diberikan edukasi. Remaja mampu memahami penyebab, gejala, pencegahan, serta pemanfaatan bahan alami seperti jahe, kunyit, sereh, madu, dan pepaya sebagai alternatif penanganan awal. Hasil analisis statistik menggunakan uji Paired T-Test menunjukkan adanya perbedaan yang signifikan antara nilai pretest dan post-test (p<0,001), sehingga edukasi kesehatan berbasis bahan alam dapat meningkatkan pengetahuan remaja mengenai pengendalian asam lambung.
Edukasi Penggunaan Obat Antiepilepsi yang Tepat sebagai Strategi Peningkatan Kepatuhan Iin Ernawati; Silfiana Nisa Permatasari; Eziah Ika Lubada; Selly Septi Fandinata; Wardah Rahmatul Islamiyah
Jurnal Pengabdian Masyarakat Bhinneka Vol. 4 No. 4 (2026): Juli
Publisher : Bhinneka Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58266/jpmb.v4i4.1546

Abstract

Epilepsi ditandai dengan terjadinya kejang yang tidak dipicu setidaknya dua kali, dengan selang waktu minimal 24 jam, akibat pelepasan berlebihan atau aktivitas neuron abnormal yang terjadi sebagian atau secara umum di otak. Penggunaan obat antiepilepsi adalah salah satu hal yang dapat digunakan untuk mencegah kekambuhan kejang. Pemberian intervensi untuk meningkatkan pemahaman dari pentingnya patuh minum obat adalah hal yang penting bagi pasien epilepsi. Salah satu kegiatan yang menjadi upaya peningkatan kepatuhan adalah pengabdian kepada komunitas pasien epilepsi. Pengabdian kepada masyarakat ini dilakukan pada anggota komunitas ODE (Orang Dengan Epilepsi). Kegiatan ini dihadiri oleh anggota komunitas yang menjadi penyintas epilepsi serta para orang tua atau caregiver yang menjadi pendamping orang dengan epilepsi. Tujuan diadakannya pengabdian masyarakat ini adalah untuk meningkatkan pemahaman tentang pentingnya mematuhi minum obat bagi pasien epilepsi. Kegiatan ini dilakukan dengan metode ceramah, tanya jawab, serta diskusi dan berbagi pengalaman dalam mengelola kejang dan penggunaan obat antiepilepsi antaranggota komunitas ODE yang hadir. Setelah pemberian materi edukasi, banyak feedback dari anggota komunitas melalui beberapa pertanyaan yang diajukan, di antaranya mengenai bagaimana mendapatkan informasi tentang interaksi obat, penggunaan obat, pemicu kejang serta efek samping yang paling sering muncul. Untuk melanjutkan monitoring, perlu adanya pendampingan berkelanjutan serta inovasi intervensi yang dapat diberikan kepada anggota komunitas epilepsi agar tetap patuh minum obat. Kegiatan pengabdian masyarakat ini menjadi salah satu wadah untuk sesama anggota komunitas berkumpul dan saling berbagi informasi tentang kontrol kejang serta mendapatkan informasi dan motivasi agar tetap terus mengonsumsi obat antiepilepsi.
The Correlation Between Pharmacological Rationality and Therapeutic Outcomes in Patients with Gout at RSI Siti Khadijah Palembang Rennie Puspa Novita; Annisa Amriani; Vitri Agustiarini; Fitriya Fitriya; Selly Septi Fandinata; Norma Nisya
Jurnal Kefarmasian Indonesia VOLUME 15, NUMBER 1, FEBRUARY 2025
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Gout is a kind of arthritis characterized by the presence of elevated amounts of uric acid in the bloodstream (hyperuricemia), leading to the accumulation of monosodium urate (MSU) crystals within the joints. The appropriate utilization of medications in individuals with gout can significantly impact the efficacy of treatment. The objective of this study is to establish a correlation between pharmacological rationality and therapeutic outcomes among gout patients at RSI Siti Khadijah Palembang from January 2020 to December 2022. The present work employs an observational analytic approach, utilizing cross-sectional and cohort study designs. The data were collected retrospectively by the utilization of the total sampling approach, encompassing a complete sample size of 32 patients. The utilization of rationality drugs yielded a 100% accuracy rate in terms of diagnosis, indication, patient selection for urate-lowering therapy, and 93.55% for analgesic anti-inflammatory treatment patient. The correct drug was administered in 100% of cases, while the appropriate dosage for urate-lowering therapy was achieved in 90.625% of instances and 100% for analgesic anti-inflammatory treatment. The route and timing of drug administration were both executed correctly in 100% of cases, and a high level of vigilance for potential side effects was maintained at 100% accuracy. The findings from Fisher's exact test demonstrated a statistically significant association between the effectiveness of urate-lowering medication and analgesic anti-inflammatory treatment in terms of obtaining normal uric acid levels (p<0.05) and reducing pain levels in individuals with gout (p<0.05). The judicious utilization of pharmaceutical substances is a viable approach for attaining desired therapeutic outcomes.