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The Effect of Pre-Operating Antibiotic Prophylaxis on Post C-Section Infection In RSUD DR. Soetomo Period January 2021 – June 2021 Mariska Nuriana; Sri Ratna Dwiningshih; Danti Nur Indiastuti; Rebekah J. Setiabudi
International Journal of Social Service and Research Vol. 2 No. 1 (2022): International Journal of Social Service and Research (IJSSR)
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/ijssr.v2i1.68

Abstract

Cesarean section has some risk of around 90% post operative morbidity caused by Surgical Site Infection. The use of prophylactic antibiotics is one of the prevention of surgical wound infections with a decrease of about 30-65%. This study will use a prospective and cross-sectional study design, to determine the relationship between the use of preoperative prophylactic antibiotics on the prevention of infection after cesarean section. The results is From 72 cesarean section patients, it can be concluded that the age group of most cesarean section patients in this study was the age group of 20-35 years. The highest BMI group in cesarean section patients was with BMI > 30 by 43.1%. The most indications for cesarean section patients are patients with a history of previous cesarean section with a total of 30 people. The most prophylactic antibiotic use was cefazolin as much as 95.8% The incidence of infection in patients using cefazolin prophylactic antibiotics was 3 patients out of 69 patients, while the incidence of infection who did not use cefazolin was 1 patient out of 3 patients. There is a relationship between the use of preoperative prophylactic antibiotics on the prevention of infection after cesarean section
PENGEMBANGAN KADER SEKOLAH MENENGAH UNTUK MENURUNKAN INSIDEN THALASSEMIA DI KABUPATEN BULAK, SURABAYA Annette d’Arqom; Danti Nur Indiastuti; Zamal Nasution; Rezi Ramawan Melbiarta
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 5 No. 2 (2021): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v5i2.2021.267-273

Abstract

AbstrakThalaasemia merupakan penyakit genetik yang menyebabkan penurunan atau ketiadaan hemoglobin, yang disebabkan oleh mutasi genetik pada gen α dan/atau gen β globin. Gejala utamanya adalah anemia yang bervariasi dari sedang hingga berat yang memerlukan transfusi rutin setiap bulan. Memutus mata rantai atau pencegahan thalassemia adalah satu-satunya cara dalam menangani penyakit genetik ini. Selain itu, karena perkawinan usia muda (10-24 tahun) merupakan hal yang umum di Indonesia, maka diperlukan edukasi mengenai pengenalan status dan risiko penyakit ini sejak usia dini, sebelum menikah, untuk menghentikan bayi baru lahir penderita thalassemia mayor. Mengatasi masalah di atas membutuhkan penyebaran informasi dan pelatihan yang berkelanjutan. Salah satunya adalah SAHABAT THALER, yaitu: gerakan kader mahasiswa yang paham dan siap menyebarkan ilmu ke lingkungan dan sesama. Memanfaatkan kegiatan ekstrakurikuler seperti OSIS, PMR, Rohis, dll, diharapkan pengetahuan tentang Thalasemia dapat disebarluaskan secara efektif dan efisien, terutama kepada individu usia subur. Kegiatan inisiasi ini diawali dengan pelatihan online untuk 20 kader mahasiswa dan 1 dosen pembimbing. Pelatihan diberikan oleh para ahli Farmakologi Molekuler, Patologi Klinik, Psikiatri, dan orang tua penderita Thalassemia. Pelatihan tersebut meliputi mengenal dasar-dasar Thalassemia, terapi dan skrining Thalassemia, pentingnya donor darah, aspek psikososial Thalassemia, dan berbagi pengalaman orang tua penderita Thalassemia. Para kader kemudian dibagi menjadi 4 kelompok kecil dan dipandu oleh fasilitator untuk kemudian menonton film dokumenter tentang Thalassemia dan membuat proyek mandiri yang selanjutnya disebarluaskan kepada 83 rekan sejawat. Respon lengkap yang diterima berjumlah 17 dari 20 kader, dengan 35,29% responden pernah mendengar tentang Thalassemia dan tidak ada yang memiliki keluarga atau teman dengan Thalassamia. Namun mereka memiliki pengetahuan yang baik tentang Thalassemia sebelum pelatihan baik (rata-rata 90,16%, kisaran 66,67-100%) dan meningkat setelah pelatihan (rata-rata 91,67%, kisaran 83,33-100%). Usai pelatihan, empat produk yang terdiri dari dua video, satu Instagram, dan satu poster dibuat dan disebarluaskan kepada rekan sebaya. Pembinaan kader kelompok sebaya diperlukan untuk meningkatkan kesadaran penyakit genetik dan pentingnya skrining pranikah.Kata Kunci: kader SMU, Thalassemia, Teman SebayaAbstractThalassemia is a genetic disease that causes decreasing or absence of hemoglobin, caused by a genetic mutation in the alpha gene or/and beta-globin gene. The main symptom is anemia which varies from moderate to severe which requires regular transfusions every month. Breaking the chain of Thalassemia or prevention is the only way in dealing with this genetic disease. Moreover, since young marriage (10-24 years) is common in Indonesia, education is needed regarding the recognition of the status and risk of this disease from an early age, before marriage, to stop the newborn with Thalassemia major. Addressing the above problems requires continuous information dissemination and training. One of these efforts is SAHABAT THALER, which is the movement of student cadres who understand and are ready to spread knowledge to the environment and peers. Taking advantage of extracurricular activities, knowledge of Thalassemia is expected to be effectively and efficiently disseminated, especially to individuals of childbearing age. This initiation activity began with online training for 20 student cadres and 1 supervisor. Training is provided by experts in Molecular Pharmacology, Clinical Pathology, Psychiatry, and parents of Thalassemia patients. The training includes getting to know the basics of Thalassemia, therapy, and screening for Thalassemia, the importance of blood donation, psychosocial aspects of Thalassemia, and sharing experiences of parents with Thalassemia. The cadres were then divided into 4 small groups and guided by the facilitator to then watch a documentary film about Thalassemia and create an independent project which was further disseminated to 83 peers. From 20 cadres, 17 complete response was received. From the response, 35.29% ever hear about Thalassemia and no one has family or friends with Thalassemia. However, they have a good knowledge of Thalassemia before the training is good (mean 90.16%, range 66.67-100%) and increase after the training (mean 91.67%, range 83.33-100%). After the training, four products which are two videos, one Instagram, and one poster were created and disseminated to the peers. The development of peer group cadres is necessary to increase the awareness of the genetic disease and the importance of pre-marital screening.Keyword: High School cadre, Peers, Thalassemia
Skrining Pendahuluan Toksisitas Beberapa Tumbuhan Benalu terhadap Larva Udang Artemia Salina Leach DANTI NUR INDIASTUTI; SRI PURWANINGSIH; YUANI SETIAWATI; NOOR CHOLIES
JURNAL ILMU KEFARMASIAN INDONESIA Vol 6 No 2 (2008): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1138.28 KB)

Abstract

The brine shrimp lethality test (BSLT) is considered as a useful tool for preliminary assessment of toxicity. It has also been suggested for screening of pharmacological activities of plant extracts. The bioactivity of eight methanol extracts of four parasite plants and two host plants were evaluated using the brine shrimp lethality assay. The results showed that all methanol extracts of the host plants did not have any indication of toxicity The LC50 of methanol extract of Moringa pterygosperma stem was 1085.44±84.32 µg/ml, and of Ficus refusal stem was 1240.86±50.71 µg/ml. But methanol extracts of whole parts of parasite plants showed toxicity to Artemia Salina Leach. The LC50 of methanol extract of Loranthus peretandrus herb parasite was 175.66±29,24 µg/ml while that of Elytranthe evenia leaf parasite was 327.15±38.66 µg/ml; of Elytranthe evenia stem parasite was 320.39±39.57 µg/ml; of Elytranthe evenia flower parasite was 456.79±15.69 µg/ml; of Scurulla atropurpurea herb parasite was 176.44±28.46 µg/ml; and of Viscum articulatum parasite was 53.79±10.83 µg/ml.
Effect of Carrots (Daucus carota L.) on Gastric Histopathology of Piroxicam-Induced Mice as a Peptic Ulcer Prevention Jennifer Susanto; Danti Nur Indiastuti; Gondo Mastutik
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 13 No. 2 (2022): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V13I22022.88-92

Abstract

Highlights:1. Carrots (Daucus carota L.) can reduce the side effects of non-steroidal anti-inflammatory drugs (NSAIDs) due to its gastroprotective components.2. Histopathological studies of the gastric inflammation signs showed that carrots can prevent NSAID-induced peptic ulcers. AbstractIntroduction: Non-steroidal anti-inflammatory drugs (NSAIDs) consumption contributes significantly to gastrointestinal morbidity, including peptic ulcers. NSAIDs cause gastric mucosal damage by inhibiting PGE2 and PGI2 secretion, increasing HCl secretion, and also causing local irritation and neutrophil adhesion. Flavonoids and chlorogenic acid are gastroprotective agents found in carrots (Daucus carota L.). Therefore, this study aimed to validate the effect of carrots on gastric histopathology of piroxicam-induced mice.Methods: This was an experimental study using a post-test-only control group design. 35 mice were divided into 5 groups and were allowed to adapt for 1 week. The negative control group received 0.25 mL aqua dest, while the positive control group received 0.104 mg famotidine. Group A, B, and C received carrot extract with each dosage was 200 mg/kgBW, 300 mg/kgBW, and 400 mg/kgBW. The mice were induced 2 hours later with 0.052 mg piroxicam. The treatments lasted 14 days. Each stomach was taken and examined on the 15th day. Afterward, histopathological preparations were made.Results: The results of the histopathological signs of inflammation using the Kruskal-Wallis method showed p = 0.000, indicating that there was an effect of the carrot extract in preventing the inflammation on the gastric histopathology (p < 0.05).Conclusion: In conclusion, this study confirmed that carrot extract is more effective in avoiding peptic ulcers due to NSAID consumption.
THE IMPORTANCE OF KNOWLEDGE ABOUT HEALTH PROTOCOLS FOR THE PREVENTION OF COVID-19 TRANSMISSION IN NON-MEDICAL STUDENTS OF SURABAYA, INDONESIA Ekiyanti, Khisma; Nadia Mardiana Hudan; Grawira Drana Putra Respati; Hamzah Rafly Rahman; Danti Nur Indiastuti
Journal of Community Medicine and Public Health Research Vol. 3 No. 2 (2022): Journal of Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.778 KB) | DOI: 10.20473/jcmphr.v3i2.32856

Abstract

Lack of public compliance with the implementation of health protocol activities in daily life has resulted in increased cases of Covid-19 in Indonesia, so the government issued the latest policy regarding the health protocol, namely 6M, which consists of wearing masks, maintaining hand hygiene, maintaining distance, reducing mobility, staying away from crowds, and avoid eating together. This study aims to educate and make the public more aware of the importance of health protocols during the Covid-19 pandemic. This research used total sampling method. The target of the counseling was non-medical students in Surabaya who took part in Covid-19 educational counseling by filling out complete pre-test and post-test questions. The results obtained were an increase in the average score (17.26 points) on tests filled before and after the educational presentation of health protocols with a value of p<0.001 (p<0.05), and 34 of them showed higher post-test scores. From the data that obtained from 92 samples, there was an increase and significant difference in knowledge about 6M health protocols after an online educational presentation given to non-medical students in Surabaya as evidenced by the increase in average score between pre-test and post-test.
CARING FOR PUERPERIAL MOTHERS THROUGH THE UTILIZATION OF TRADITIONAL HERBS TO OPTIMIZE THEIR HEALTH Nurina Hasanatuludhhiyah; Danti Nur Indiastuti; Yuani Setiawati; Nurmawati Fatimah
Jurnal Layanan Masyarakat Vol. 7 No. 2 (2023): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v7i2.2023.161-172

Abstract

Puerperium is a critical period in which mothers often experience physical and psychological problems, however it is the beginning of the breastfeeding process and determines the success of exclusive breastfeeding. The use of traditional herbs for postpartum mothers is part of Indonesian culture that is starting to be abandoned in urban area. This community service activity aims to increase the knowledge, attitudes and behaviour of the community regarding the importance of postpartum maternal health care and the use of traditional herbs with proper processing methods as a promotive and preventive treatment. This activity was carried out in Gubeng Surabaya District with three stages including preparation, implementation of activities and evaluation. In the preparation stage, a situation analysis was performed. Activities were conducted by delivering lectures, discussions, video demonstrations and training. The evaluation was carried out by obtaining feedback from the social and community empowerment section as well as the pre-test and post-test questionnaires filled out by the participants. Based on the evaluation, the community service can increase participants' knowledge about postpartum health care and lactation management, thereby increasing awareness to play an active role by disseminating information to the community about the importance of family and the neighbourhood support for postpartum and breastfeeding mothers. The participants 'knowledge about the use of traditional medicinal plants for the maintenance of postpartum health and successful breastfeeding also increased, accompanied by an increase in the participants' willingness to prepare traditional jamu from fresh herbal ingredients themselves. This community service needs to be carried out in a sustainable manner with innovative delivery methods.
Mental health and decision-making participation of adolescent orphans: A pilot study Annette d'Arqom; Farhan Nurdiansyah; Danti Nur Indiastuti; Mhd Zamal Nasution; Nurmawati Fatimah; Sri Purwaningsih; Yuani Setiawati; Kusuma Eko Purwantari
Jurnal Keperawatan Padjadjaran Vol. 11 No. 3 (2023): Jurnal Keperawatan Padjadjaran
Publisher : Faculty of Nursing Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkp.v11i3.2358

Abstract

Background: Mental health has been brought to attention lately, with the increase of mental health problems during adolescence. In Indonesia, it is reported that one-third of adolescents develop mental health disorders. Childhood grief, separation from the family, child labor, or abuse affect the orphans’ mental health, including their decision-making participation. Purpose: As a pilot study, this study would like to investigate the mental health conditions and decision-making participation among orphans in one orphanage in Mojokerto district, East Java, Indonesia.Methods: This cross-sectional study utilizes the Depression Anxiety Scale Youth version (DASS-Y) and Child and Adolescent Participation in Decision Making Questionnaire (CAP-DMQ). Thirty-five adolescent orphans of one orphanage in Mojokerto were recruited using convenience sampling. The frequency of respondents’ mental health and decision-making participation were measured, and the mean differences between each group of sociodemographic factors were measured using the Mann-Whitney U test or the Kruskal Wallis test. Association between mental health and decision-making participation was calculated using Chi-square test.Results: The results show that 40% of respondents were categorized as having mild mental health problems, including depression, anxiety, and stress. Mental health problems are mostly found in males (22.90%) and elementary school (20%). The participation of the orphans in decision-making is considered good, with a median of 25.5. The bivariate analysis concludes the association between anxiety, age, grade, and decision-making participation (p= 0.024, p= 0.029, p=0.029, respectively).Conclusion: Taken together, attention to orphans, especially adolescents, and their problems are necessary to reduce the health discrepancies within these vulnerable groups. Broader respondents are needed to understand the complete picture of mental health conditions among Indonesian adolescent orphans, including late adolescents.
The Effects of Hormonal Factor on the Degree of Acne Vulgaris Severity Alarik L., Albertus; Indiastuti, Danti Nur; Astari, Linda; Setyaningrum, Trisniartami
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 2 (2023): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.2.2023.126-129

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Background: Acne vulgaris is a disease in the form of chronic inflammation of the pilosebaceous follicles with multifactorial causes. Acne vulgaris is a very common skin disease with a prevalence of 85%  in the age range of 18-25 years. There are aggravating factors that can exacerbate acne vulgaris, including hormonal factors. However, the study about how strong the effects of hormonal factors and on acne severity is really limited. Purpose: The objective of this research is to determine how strong hormonal factors contribute on the severity of acne vulgaris. Methods: This was a cross-sectional retrospective study using secondary data obtained from 199 patients at the Dermatology and Venereology Outpatient Unit of RSUD Dr. Soetomo from January- December 2019. The data were analyzed using SPSS with regression analysis.Result: Hormonal factors significantly influenced the degree of acne vulgaris severity (P-value=0.030). Based on the logistic regression model, it can be found that hormonal factors influence the degree of acne vulgaris by 70% Conclusion: The effect of hormonal factors on the severity of acne vulgaris is 70%.
PEMBERDAYAAN KADER KESEHATAN TENTANG TANAMAN OBAT BERKHASIAT ANTI HIPERTENSI PADA MASYARAKAT DI DESA KENTONG KECAMATAN GLAGAH KABUPATEN LAMONGAN: PEMBERDAYAAN KADER KESEHATAN TENTANG TANAMAN OBAT BERKHASIAT ANTI HIPERTENSI PADA MASYARAKAT DI DESA KENTONG KECAMATAN GLAGAH KABUPATEN LAMONGAN Fatimah, Nurmawati; Mustika, Arifa; Setiawati, Yuani; D’Arqom, Annette; Purwaningsih, Sri; Rochmanti, Maftuchah; Nur Indiastuti, Danti; Hasanatuludhhiyah, Nurina; Akbar Kurniawan, Mohammad
J-Dinamika : Jurnal Pengabdian Masyarakat Vol 9 No 2 (2024): Agustus
Publisher : Politeknik Negeri Jember

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Abstract

Pemberdayaan kader kesehatan dalam program GERMAS melalui Posbindu di Desa Kentong, Kecamatan Glagah, Kabupaten Lamongan bertujuan untuk meningkatkan pengetahuan tentang pemanfaatan tanaman obat yang berkhasiat sebagai anti hipertensi. Tingginya prevalensi pasien hipertensi di daerah tersebut, diduga akibat dari kepatuhan berobat yang rendah, pengetahuan perilaku gaya hidup dan diet yang sehat masih belum optimal, serta minimnya informasi dan pengetahuan tentang pemanfaatan tanaman obat pada pasien hipertensi. Solusi yang ditawarkan untuk menyelesaikan permasalahan tersebut adalah memberikan penyuluhan tentang materi pentingnya mengelola hipertensi dengan baik, pengobatan rutin, perilaku gaya hidup serta diet sehat bagi pasien hipertensi,  sosialisasi tanaman obat berkhasiat sebagai antihipertensi dan demonstrasi pelatihan pembuatan sediaan dari tanaman obat. Metode yang digunakan melalui survei, kuesioner dan penyuluhan penyampaian materi, serta demonstrasi langsung di depan peserta. Ditemukan pada kuesioner pretes bahwa kader belum paham tentang ragam tanaman obat dan pengolahan yang tepat, setelah dilakukan penyuluhan dan demonstrasi terjadi peningkatan pengetahuan dengan para kader mampu menjawab pos tes dengan benar, peserta aktif berdiskusi secara oral, hal tersebut sebagai indikator bahwa peserta antusias dan dapat tercipta kader kesehatan yang mandiri.
Efek Analgesik Ekstrak Etanol Zingiber cassumunar Roxb. pada Mencit dengan Metode Writhing Test Bajuber, Qonita; Indiastuti, Danti Nur; Kusuma, Edward
Jurnal Medik Veteriner Vol. 3 No. 1 (2020): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (437.601 KB) | DOI: 10.20473/jmv.vol3.iss1.2020.45-50

Abstract

Penelitian bertujuan untuk menguji efek analgesik ekstrak etanol Zingiber cassumunar Roxb. pada mencit yang diinduksi dengan asam asetat. Penelitian ini merupakan penelitian eksperiment  posttest only control design, menggunakan metode writhing test. Sampel penelitian terdiri dari 25 mencit terbagi dalam tiga kelompok perlakuan ekstrak Zingiber cassumunar Roxb.; P1, P2, dan P3, dengan masing-masing dosis 100 mg/kgBB, 200 mg/kgBB, 400 mg/kgBB, kelompok kontrol negatif aquades (K-), serta kelompok kontrol positif aspirin (K+). Hasil penelitian menunjukkan bahwa (P1) dan (P2) signifikan menurunkan jumlah geliat pada mencit dibandingkan (K-) (p < 0,05), dengan persentase penurunan jumlah geliat sebesar 49,53% dan 57,01%, sedangkan (P3) tidak menunjukkan aktivitas analgesik. Ekstrak Zingiber cassumunar Roxb. dosis 100 mg/kgBB dan 200 mg/kgBB tidak memiliki perbedaan yang signifikan terhadap (K+) untuk mengurangi rasa nyeri.
Co-Authors Abdurrahman Hasyim Asy’ari Adila, Vatine Agung Dwi Wahyu Widodo Akbar Kurniawan, Mohammad Alarik L., Albertus Alimsardjono, Lindawati Anastassya Yuniar Setyo Putri Annette d’Arqom, Annette Ardana, Arin Aurilia Arifa Mustika Arifandi, Yoga Akbar Arnapi, Almara Diva Puteri Bajuber, Qonita Bakhtiar, Arief Desi Rahmah Sari Dewangga Sakti Satria Kinasih Dewi Tri Utami, Mahrumi Dinda Divamillenia Dini Indah Berlianti Doman, Zahras Azimuth Effendi, Wiwin Is Ekiyanti, Khisma Farhan Nurdiansyah Fatimah, Nurmawati Gabriel Pedro Mudjianto Gondo Mastutik Grawira Drana Putra Respati Hamzah Hamzah Hamzah Rafly Rahman Herdiyanti Herdiyanti Indri Safitri Mukono, Indri Safitri Jennifer Susanto Jihan Nur Fauziah Jonathan Christianto Sutadji Junaidah Yusof Kawilarang, Arthur Pohan Kusuma Eko Purwantari Kusuma, Edward Putra Lifindra, Billy Yanssen Linda Astari, Linda Maftuchah Maftuchah Mariska Nuriana Mhd Zamal Nasution Mia Ratwita Andarsini Muhammad Hafizh Muhammad Raihan Habibi Nabil Alfin Juhri Nadia Mardiana Hudan Natasya Ariesta Selyardi Putri NOOR CHOLIES Nurina Hasanatuludhhiyah Nurul Wiqoyah, Nurul Octaviana Galuh Pratiwi Pangkerego, Margareth Ayu Caroline Pascalis Fabian Peter Asa Prasetyo, Hersati Purwanta, Marijam Puteri, Fira Adilah Putu Agus Arsana, I Qorib, Mohammad Fathul Raden Mohamad Herdian Bhakti Rebekah Setiabudi, Rebekah Resti Yudhawati Rezi Ramawan Melbiarta Rezy Ramawan Melbiarta Rosyid, Alfian Nur Rusuldi, Reyna Cesariyani R. Savitri, Natasha Hana Shaohong Lai Shofiuddin Al Mufid Sri Purwaningsih Sri Ratna Dwiningshih Trisnawati Trisnawati Trisniartami Setyaningrum Wahyunitasari, Manik Retno Wibowo, Idznika Nurannisa Wiwin Retnowati Yuani Setiawati Zamal Nasution