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All Journal JURNAL PENDIDIKAN TAMBUSAI Jurnal Kesehatan Tambusai Jurnal Buana Farma Proceedings of the International Conference on Nursing and Health Sciences JIFI (Jurnal Ilmiah Farmasi Imelda) Duta Pharma Journal Proceeding of International Conference Health, Science And Technology (ICOHETECH) International Journal of Health, Engineering and Technology Majalah Cendekia Mengabdi Inovasi Jurnal Pengabdian Masyarakat (IJPM)
Septian Maulid Wicahyo
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Duta Bangsa Surakarta, 57552, Jawa Tengah, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Identification Formula For Hydroquinone Compound Content In Bulk Body Lotion Cosmetic Preparations Sold On E-Commerce Ananda Saputra; Septian Maulid Wicahyo; Siwi Hastuti
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.608

Abstract

The distribution of skin-whitening cosmetics, especially body lotions, through e-commerce platforms is increasing and may contain hazardous ingredients such as hydroquinone. Hydroquinone is a compound that is prohibited for use in cosmetics because it can cause side effects such as dark spots on the skin, allergic reactions, irritation, brain damage, and cancer. This study aims to identify and determine the levels of hydroquinone in body lotion cosmetics sold on e-commerce platforms. This is an observational study with a descriptive approach. A total of three body lotion samples were analyzed qualitatively using a color reaction test with FeCl₃ reagent and thin-layer chromatography (TLC) method, and analyzed quantitatively using ultraviolet-visible spectrophotometry (UV-Vis). The hydroquinone content was determined based on the calibration curve of the standard solution at the maximum wavelength. The results showed that two of the three samples tested positive for hydroquinone in the qualitative test. Quantitative analysis showed that the hydroquinone content in sample 1 was (70.48 ± 0.0044)% and in sample 3 was (67.88 ± 0.0021)%. These levels do not meet cosmetic safety requirements according to the regulations of the Food and Drug Supervisory Agency (BPOM). It can be concluded that there are still body lotions circulating on e-commerce platforms that contain high levels of hydroquinone, so stricter supervision and increased public education regarding cosmetic safety are needed.
Determination Of Sun Protection Factor (SPF) Values Of Water, Ethyl Acetate, And N-Hexane Fractions Of Kepok Banana Flowers (Musa acuminata x M. balbisiana) Using The UV-Vis Spectrophotometry Method Evi Eriani; Septian Maulid Wicahyo; Tatiana Siska Wardani
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.636

Abstract

Indonesia as a tropical country faces high UV exposure which causes premature skin aging and cancer risk, so it is necessary to have natural sunscreen from antioxidant-rich plants such as kepok banana flowers (Musa acuminata x M. balbisiana). This study aims to determine the Sun Protection Factor (SPF) value and protection category of water, ethyl acetate, and n-hexane fractions of kepok banana flowers. This type of research is descriptive experimental with ethanol maceration method, multilevel fractionation, phytochemical screening, TLC, and UV-Vis spectrophotometry (290-320 nm, Mansur formula).The results showed that the different types of solvents in each fraction influenced the resulting SPF value. The ethyl acetate fraction showed the highest protective activity compared to the other fractions. The SPF values ​​of the kepok banana flower water fraction with concentrations of 60 ppm, 80 ppm, 100 ppm, 120 ppm, and 140 ppm were 4.662; 7.757; 9.055; 11.944; 15.264, respectively, with moderate-ultra protection. The ethyl acetate fraction obtained SPF values ​​of 18.433; 18.968; 19.203; 19.672; 20.203 with ultra protection. The n-hexane fraction obtained SPF values ​​of 1.190; 1.762; 2.278; 3.575; 4.598 with the category of no-moderate protection.. Concludedthat kepok banana flowers have potential as a natural sunscreen agent, where the ethyl acetate and water fractions provide the most optimal sun protection effectiveness (SPF) compared to the n-hexane fraction.
Determination Of Sun Protective Factor (SPF) Values In N-Hexane, Ethyl Acetate, And Water Fractions Of Ethanol Extract Of Tamarind Eggplant (Solanum Lasiocarpum Dunal.) Peel With UV-VIS Spectrophotometry Method Natalia Riska Angelinda; Septian Maulid Wicahyo; Alfina Nurrahman
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.685

Abstract

Excessive UV exposure causes skin damage, so natural sunscreen alternatives are needed. This experimental descriptive study aims to identify and measure the Sun Protection Factor (SPF) value of ethanol extract and n-hexane, ethyl acetate, and water fractions from Solanum lasiocarpum Dunal fruit peel in vitro using UV-Vis spectrophotometry. The population of the entire skin simplicia from Tanjung Hulu, Pontianak; a sample of 500 g of powder (mesh 40) was extracted and fractionated. Instruments include a Thermo Scientific UV-Vis spectrophotometer (290-320 nm), rotary evaporator, TLC plate; SPF was calculated using the Mansur equation and Lambert-Beer validation linear regression. The results showed the highest SPF of ethyl acetate fraction (36.97 at 500 ppm, high category), while the ethanol extract (9.32), n-hexane (6.71), and water (6.76) were low. Phytochemical screening was positive for alkaloids, terpenoids, phenolics, and flavonoids. In conclusion, the ethyl acetate fraction has optimal potential for the development of sunscreen cosmetics.
Co-Authors Alfina Nurrahman Ananda Saputra Anna Fitriawati Apriliawan, Hidayah Artini, Kusumaningtyas Artini, Kusumaningtyas Siwi Bagas Ardiyantoro Danang Raharjo Erikania, Susanti Evi Eriani Fadilla, Fitri Hansa Fauzi Rifqi Pramita Fitriani, Noviana hanif fathur rohman, muhammad Listyani, Tiara Ajeng Nadia Nadzifah, Ifah Natalia Riska Angelinda Nur Hikmah, Siti Oktavia Nanda lestari Permata, Bangkit Riska Pratama, Kharisma Jayak Qurrota'Ain, Rusyda Rahmatillah, Annie rani, fahrenza meta Ratna Safitri Shinta Putri Rahmawati Siwi Hastuti Tiara Ajeng Litsyani tri Mastuti, eni uswatun hasanah, alfiana Voen-Na, Cut Dara Wardani, Tatiana Siska