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Sumaiyah, Sumaiyah
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Journal : International Journal Of Science, Technology

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Synthesis Of Silver Nanoparticles (Agnp) From The Extract Of Kemloko Fruit (Phyllantus Emblica L.) Mukhlisa, Ida; Masfria, Masfria; Sumaiyah, Sumaiyah
International Journal of Science, Technology & Management Vol. 3 No. 5 (2022): September 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i5.620

Abstract

Nanoparticles are nano-sized materials that are widely used because they have many advantages and very beneficial benefits. One method of making nanoparticles biologically. In the process of chemically synthesizing silver nanoparticles, nanomaterials are toxic and not environmentally friendly. So, other options are used, such as biological synthesis with natural materials as reducing catalysts and plant extract bioreductors that can reduce the amount of dangerous materials in the waste. This study aims to make nanoparticles from kemloko ethanol extract with biological methods. Extraction was carried out by the maceration method and synthesis of silver nanoparticles by a biological method with functional group analysis characteristics using FTIR. The results of this study indicate that these nanoparticles indicate that silver nanoparticles can be synthesized biologically for silver nanoparticles and the FTIRcharacteristic results show that silver nanoparticles contain OH, C=O, N=O, C-O, and C-H groups.
Formulation And Evaluation Of Nanoemulgel Clove Leaf Oil (Sygyzium Aromaticum) (L.) Merr & Perry As Anti-Acne Dasawanti, Yoan; Reveny, Julia; Sumaiyah, Sumaiyah
International Journal of Science, Technology & Management Vol. 3 No. 6 (2022): November 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i6.681

Abstract

Acne also known as acne vulgaris, is an inflammatory condition of the polysebaceous layer that is brought on by the buildup of keratin. Active oil glands under the skin cause acne. Androgen hormones function as a stimulant for this activity. Cloves are herbal plants that contain essential oil chemicals. The chemical composition of clove leaf oil is mainly composed of eugenol. Eugenol has pharmacological effects as antibacterial, analgesic and anti-inflammatory. Nanoemulsion is a nanocarrier that gets a lot of attention, because of its small particle size so that it can be thermodynamically stable and can increase drug penetration. Recent advances in nanoemulsion research have created new prospects in a number of industries, including pharmaceuticals, biotechnology, food, and cosmetics. This research was conducted by formulating clove leaf oil into nanoemulgel preparations, followed by evaluation of the preparations and testing of antibacterial activity against acne-causing bacteria. The result of the nanoemulgel formulation is yellow, smells of clove leaf oil, is transparent and homogeneous. Nanoemulgel viscosity 3434-3109 M.Pas, pH 6.15-6.41 and particle size 12.3-13.3 nm. Physical studies of nanoemulgel been carried out for three cycles and there is no change in color, change in odor and phase separation. The results of the antibacterial activity of Staphylococcus epidermidis at NEG1 12.03 mm, NEG2 16.93 mm, NEG3 18.96 mm and EG 18.03 mm. The results of the antibacterial activity of Propionibacterium acnes at NEG1 11.50 mm, NEG2 16.16 mm, NEG3 18.03 mm and EG 17.33 mm. The results of the study concluded that clove leaf oil nanoemulgel with a concentration of 7% was the best formula, because it is stable during storage and has the greatest antibacterial activity compared to emulgel.
Co-Authors . Marianne Abdullah, Assyari Agus Syahrani Astuti, Dwi Sutri Baehaqi Bestari, Khansa Candra Br Tarigan, Elma Rosdawati Chandra, Reza Darmayanti, Septi Tri Dasawanti, Yoan Denny Satria, Denny Edison Edison Ernawati Ernawati Estefania, Kaban Vera Hanum, Tengku Ismanelly Haris, Aidil Hasibuan, Poppy Anjelisa Zaitun Hasibuan, Wan Fadilla Helda Syahfari Hery Widijanto Himatul Husna, Arina Illian, Didi Nurhadi Jansen Silalahi Jayus Jayus Julia Reveny KHAIRI, AKMAL lubis, muhammad fauzan Mairita, Desy Maldefsta, Arya Masfria Maulana, Dika Meyliana Mitra, Rifa Muhammad Soim, Muhammad Mukhlisa, Ida Mustafa Mutasir Mutasir, Mutasir Nadaresta, Maria Napitupulu, Marisi Nurhaz Siregar, Arfah Nurwalidaini, Nurwalidaini Patah, Abdul Patriantoro . Putri Yolanda Barus, Dwi Retno Murwanti Ridha Arrasyid, Muhammad Rudang, Singgar Ni Sarin, Sarin Sayopi, Abdurrahman Siregar, Dedek Harianti Sormin, Tessa Sri Rohani, Ade Tampubolon, Keshia Taufiq Hidayat Widya Novchi, Raja Yasril Yazid