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All Journal International Journal of Public Health Science (IJPHS) e-CliniC Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Plastik Rekonstruksi Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia World Nutrition Journal Jurnal Ners Science Midwifery Jurnal Darma Agung Jurnal Sehat Indonesia (JUSINDO) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute
Wulandari, Yohannessa
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Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : World Nutrition Journal

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Role of folic acid supplementation in level of c-reactive protein in metabolic syndrome : evidence based case report Sjarkowi, Anissa Syafitri; Wulandari, Yohannessa; Trismiyanti, Trismiyanti
World Nutrition Journal Vol. 8 No. i1 (2024): Volume 08 Issue 1, August 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.i1.0003

Abstract

Introduction: The prevalence of metabolic syndrome is increasing, its progression involves an inflammatory response that has an important impact on the initiation, progressivity, and complications of several diseases such as heart disease, stroke, type 2 diabetes mellitus, and cancer. C-reactive protein (CRP) is one of the inflammation markers increased in patients with metabolic syndrome. Folic acid has a role in metabolizing homocysteine and improving endothelial function. There have been many studies conducted, but the results are still inconsistent. Method: Literature searching was conducted using PubMed, Cochrane Library, and Embase databases. MeSH terms, advanced search and eligibility criteria were used for title/abstract screening before journal review. Results: One systematic review and meta-analysis (SR-MA) and one RCT met the PICO and eligibility criteria. The SR-MA found that folic acid administration can reduce CRP level (WMD -0.94 (95% CI -1.56 – 0.32; p=0.00) at a dose of 0.15 mg/day for 12 weeks to 10 mg/day for 2 weeks, while the RCT found an insignificant result. Conclusion: Folic acid supplementation has a potential benefit to decrease CRP levels in metabolic syndrome.
Vitamin D deficiency and risk of myasthenia gravis: An evidence-based case report Wijayanthie, Nadiyah; Wulandari, Yohannessa; Rahmawati, Anni
World Nutrition Journal Vol. 8 No. i1 (2024): Volume 08 Issue 1, August 2024
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/WNJ.V08.i1.0007

Abstract

Background: An autoimmune condition known as myasthenia gravis (MG) targets the receptors for neurotransmitter acetylcholine at the neuromuscular junction, resulting in inhibition of muscle contraction. This results in muscle weakness resulting in a decrease in quality of life. Immunoregulation and muscle contractility are known to play a role in vitamin D. Literature on how vitamin D affects myasthenia gravis risk has not been widely carried out and the results are still controversial.Objective: To evaluate the association between vitamin D and MG risk.Methods: The search of the literature was conducted from PubMed, Cochrane Library, Embase, and EBSCOhost with the eligibility criteria determined by the authors. The literature search was using MeSH Term, text word, and title/abstract.Results: Two articles were selected and critically appraised. The first article shows an odds ratio of 3.96 (CI95 1.26 to 12.52), which means that myasthenia gravis has vitamin D levels almost 4 times lower than healthy population. A case-control study that followed described a comparison of mean levels of vitamin D (25(OH)D) in myasthenia gravis (mean, 18.8±8.4 ng/mL) compared to healthy controls (26.3±6.1). ng/mL) (p <0.05). Both studies revealed a strong interaction between MG and vitamin D inadequacy. Conclusion: Both studies above support the theory that vitamin D deficiency is associated with the risk of developing MG.
Co-Authors Adiningrat, Arina Fatharani Aditya Rachman, Aditya Aditya Wardhana Amanda Pitarini Utari Andayani, Diyah Eka Ari Wijayanti Badrya, Leily Daya, Mulianah Diana Sunardi Dwirini Retno Gunarti Fadhilah, Dini Fiastuti Witjaksono Haloho, Raja Mangatur Ibrahim, Febiansyah Inka A. T. Sukarno Kairupan, Timothy S. Kaka Renaldi Manikam, Nurul R. M. Marcellus Simadibrata Murdani Abdullah Mustikarani, Dewi Mutiara, Rizka Muzellina, Virly Nanda Octaviani, Pauline Octovia, Lily Indriani Purwantini, Dian Rahmawati, Anni Ramadhania, Dian Araminta Rasyid, Nurhayati M Ribuan, Consistania Simadibrata, Daniel Martin Sjarkowi, Anissa Syafitri Sutanto, Krisadelfa Tedjaatmadja, Chintya Trismiyanti, Trismiyanti Wardani, Putri Kusuma Wijayanthie, Nadiyah Wina Sinaga