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All Journal Sains Olahraga : Jurnal Ilmiah Ilmu Keolahragaan Jurnal Respirasi (JR) Respiratory Science Narra J International Journal of Health and Pharmaceutical (IJHP) The Journal of Society Medicine (JSOCMED) Medicina Biomedica Journal
Pandia, Pandiaman
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health

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The Effect of Providing Education on the Use of Inhalers on Asthma Degrees Based on the Asthma Control Test (ACT) in Patients at Tanjungpura Hospital Bayani, Sri; Tarigan, Amira Permatasari; Pandia, Pandiaman; Amelia, Rina; Jefri, Budi
Journal of Society Medicine Vol. 3 No. 10 (2024): Oktober
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i10.168

Abstract

Introduction: The main goal of asthma treatment is to control symptoms and reduce emergency department (ED) visits due to acute exacerbations. Drug delivery through inhalation is an important component of asthma management. Patients with asthma should have a good knowledge of their disease to recognize signs of worsening that can be prevented by early detection. Asthma control can be evaluated using the Asthma Control Test (ACT). To determine the effect of providing education on the use of inhalers on the degree of asthma based on the ACT in patients at Tanjungpura Regional General Hospital. Methods: This quasi-experimental study conducted from March 2024 to May 2024, used a one-group pre-test and post-test design to evaluate the effect of education via smartphone applications on asthma control (ACT). Obtained 54 patients who were diagnosed asthma at Tanjungpura Regional General Hospital. The sample consisted of asthma patients using inhalers, selected consecutively based on inclusion and exclusion criteria. Results: Most patients were female (64.8%) with ages 18-60 years (83.3%). The majority were housewives (46.2%). Post-test showed that 75.9% of patients had partial asthma control. All patients (100%) used inhalers correctly after education. There was a significant difference in ACT results before and after education (P-value 0.001) and an increase in ACT scores after the first and second education (P-value 0.002 and 0.001, respectively). Conclusion: Providing education on the use of inhalers has a positive effect on ACT scores in asthma patients, with an increase in the mean ACT score from 15.67 before education to 17.11 after the first education, and 20.96 after the second education.
Comparison of Symptoms and Lung Function in Patients with Chronic Obstructive Pulmonary Disease (COPD) Receiving Monobronchodilators and Dual Bronchodilators Lingga, Elfia Damaiyanti Br; Pandia, Pandiaman; Pradana, Andika
Journal of Society Medicine Vol. 3 No. 11 (2024): November
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i11.169

Abstract

Introduction: In COPD treatment with a monobronchodilator or dualbronchodilator, can be assessed for the prognosis of therapy outcomes provided to monitor the impact of intervention and recovery of daily activities, prevent acute exacerbations, and improve the productivity of patient’s COPD. To determine the comparison between symptoms and lung function in patients with COPD disease receiving monobronchodilator and dual bronchodilator. Method: This study is a retrospective cohort study. The research sample consists of COPD patients undergoing treatment with monobronchodilator or dualbronchodilator for a minimum of 3 months or 3 treatment visits. Symptoms are measured using mMRC and lung function is measured using spirometry (FEV1). Results: The majority of patients are male (87.1%) and over 60 years old (62.4%), with the majority being smokers (84.7%), and the most common therapy being monobronchodilator (62.4%) and dual bronchodilator (37,6%). There are differences in symptoms and lung function in patients receiving monobronchodilator and dual bronchodilator. Conclusion: The dual bronchodilator is more effective in reducing mMRC values, improving by 96.3%, and increasing spirometry values. The average FEV1 value in spirometry for patients using the dualbronchodilator increased by 13,907%, while for the monobronchodilator, it decreased by 5.589%.
Blood Eosinophil Count as a Predictor of Asthma Exacerbation Damanik, Rizki amaliah; Pradana, Andika; Pandia, Pandiaman
Journal of Society Medicine Vol. 4 No. 2 (2025): February
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i2.197

Abstract

Introduction: Asthma is a heterogeneous disease characterized by chronic airway inflammation, where eosinophils play a crucial role. Eosinophil levels are often considered a biomarker for asthma severity and treatment response. However, their relationship with asthma exacerbation severity remains unclear. This study aimed to evaluate the relationship between blood eosinophil levels and the severity of asthma exacerbations in patients at Prof. Dr. Chairuddin P. Lubis USU Hospital. Method: This study employed an analytic observational design with a retrospective cohort approach. Data were collected from 25 asthma patients through medical records, including demographic characteristics, blood eosinophil levels, and asthma exacerbation severity. The relationship between eosinophil levels and exacerbation severity was analyzed using the Whitney test. Results: The majority of asthma patients were in the 26-50 age group (44%) and predominantly female (80%). Most patients had blood eosinophil levels <100 (84%), and severe exacerbations were the most common (72%). Statistical analysis showed no significant relationship between blood eosinophil levels and asthma exacerbation severity (p = 0.976). Conclusion: This study found no significant correlation between blood eosinophil levels and asthma exacerbation severity. Other factors, such as corticosteroid use, delayed immune response, and non-eosinophilic asthma, may influence exacerbation severity. These findings emphasize the importance of a multidimensional evaluation in asthma management, including the identification of different asthma phenotypes to guide more precise treatment strategies.
Analysis of Blood Eosinophil Levels as an Indicator of Controlled Asthma Classification at the University of Sumatra Utara Hospital Damanik, Rizki Amaliah; Pradana, Andika; Pandia, Pandiaman
Journal of Society Medicine Vol. 4 No. 3 (2025): March
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i3.198

Abstract

Introduction: Asthma is a chronic inflammatory disease of the airways characterized by variable airflow obstruction. Eosinophils play a crucial role in airway inflammation and may serve as a biomarker for asthma control classification. This study aims to analyze the relationship between blood eosinophil levels and asthma control classification in patients at the University of Sumatra Utara Hospital. Methods: This was an analytical observational study with a retrospective cohort approach based on medical records. A total of 25 stable asthma patients who had been receiving inhaled corticosteroid-long-acting beta-agonist (ICS-LABA) therapy for at least one year were included. Data were analyzed using SPSS version 26, and the Kruskal-Wallis test was performed to assess the relationship between eosinophil levels and asthma control classification. Results: The majority of patients were aged 26-50 years (44%) and female (80%). Most patients had eosinophil levels <100 (84%), while 8% had levels between 100-300 and another 8% had levels >300. Regarding asthma control, 46.7% of patients were fully controlled, 43.3% were partially controlled, and 10% were uncontrolled. Statistical analysis showed a significant relationship between eosinophil levels and asthma control classification (p = 0.009), indicating that lower eosinophil levels are associated with better asthma control. Conclusion: The study found that lower eosinophil levels were associated with better asthma control. These findings suggest that blood eosinophil levels may serve as an indicator for assessing asthma control, though further research is needed to confirm this relationship.
Effects of Upper Arm and Breathing Exercise on Interleukin-6 in COVID-19 Patients Tarigan, Amira Permatasari; Listyoko, Aditya Sri; Pandia, Pandiaman; Pradana, Andika; Eyanoer, Putri Chairani; Sinaga, Sudirman Parningotan; Vera, Yeni; Firdaus, Ruby; Ramadhani, Adini Arifah
Jurnal Respirasi Vol. 10 No. 1 (2024): January 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.1.2024.36-41

Abstract

Introduction: COVID-19 disease has become a comprehensive world issue and has been declared a significant threat to global health. Interleukin-6 (IL-6) is an important inflammatory marker and one of the triggers of the cytokine storm in COVID-19, where increased levels can be an independent predictor of COVID-19 mortality. This study aimed to observe the effect of upper arm and breathing exercises on IL-6 levels in severe COVID-19 patients. Methods: The study design was quasi-experimental, with blood tests conducted before and after the examination. A total of 20 patients with confirmed COVID-19 were involved, divided into intervention and control groups. Results: Blood tests to determine baseline IL-6 levels were performed in all patients. Patients from the intervention group were given upper arm and breathing exercises for ten days, twice a day, via video tutorials on mobile phones, while patients from the control group did not receive any exercises. Patients from the intervention group obtained mean pre- and post-exercise IL-6 levels of 42.38 ± 48.48 and 16.78 ± 18.29, respectively (p = 0.005). Conclusion: Upper arm and breathing exercises showed significant changes in IL-6 levels in severe COVID-19 patients.
A Rare Case of Completely Healed Pneumomediastinum Due to Asthma Exacerbation in A Young Male Patient Tarigan, Amira Permatasari; Pandia, Pandiaman; Pradana, Andika; Hutabarat, Eva Susanti Debora; Ramadhani, Adini Arifah
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.95

Abstract

Background: The term pneumomediastinum (PNM) refers to the presence of air within the mediastinal cavity. This illness is uncommon but can arise in adolescents with severe asthma attacks. In children aged 5 to 34, the incidence of pneumomediastinum after an acute asthma attack is 1 in 25,000. Men made up the majority of patients (76 percent of all cases). Pneumomediastinum can be diagnosed with the assistance of a chest CT scan. Case: A young man was diagnosed with pneumomediastinum due to an acute asthma attack in this case report. Symptoms of uncontrolled asthma include shortness of breath that worsens with wheezing, chest tightness, and a nonproductive cough. Since the age of 12, the patient in this instance has been receiving salbutamol inhalers. The physical examination revealed polyphonic lung respiration and subcutaneous crepitus in the neck, shoulders, and anterior chest. With adequate management of an asthma episode, pneumomediastinum recovers spontaneously, followed by recurrent symptomatic status, physical examination, and radiography examination. Discussion: Acute asthma exacerbations are one of the factors that can lead to spontaneous pneumomediastinum, in which mediastinal air can permeate the tissue and generate a pneumothorax, and if there is air in the subcutaneous area, it can lead to subcutaneous emphysema. Conclusion: Pneumomediastinum was a rare incidence, pulmonologists examining young adults with acute asthma exacerbations should evaluate for pneumomediastinum. In usual asthma therapy, a chest CT-scan is essential to screen for pneumomediastinum.
PROPORTION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN CORONARY HEART DISEASE PATIENTS AT HAJI ADAM MALIK GENERAL HOSPITAL MEDAN Simanjuntak, Donal Anjar; Pandia, Pandiaman; Tarigan, Amira P
Medicina Biomedica Journal Vol 1, No 2 (2022)
Publisher : Medicina Biomedica Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/mbj.v1i2.9434

Abstract

Background: Chronic obstructive pulmonary disease and coronary heart disease are diseases that have several common risk factors, one of which is age and smoking habits. Research conducted by Enriguez et al. reported that CHD patients with COPD had a significantly increased risk of death after 1 year compared to patients with COPD. without COPD, meaning that finding the right diagnosis and appropriate treatment for CHD patients can improve the patient's quality of life and possibly reduce the mortality rate in CHD patients. outpatient treatment at the cardiology outpatient clinic, Haji Adam Malik Hospital, Medan. Results: After examining the history, questionnaire, and post-bronchodilator spirometry, the proportion of COPD patients in CHD patients was 27.50%. Conclusion: This study of the proportion of COPD in patients with coronary heart disease is quite high as much as 27.50%, so it is necessary for clinicians to carry out pulmonary function examinations in CHD patients, especially those who have risk factors for COPD so that clinicians can determine the appropriate management for the patient.
Pulmonary Function Recovery After Treatment in Drug Sensitive TB: What Factors Matter? Simbolon, Novery; Pandia, Pandiaman; Pradana, Andika; Anhar, Taufik
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025 ( Indonesia - Thailand)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.465

Abstract

Background: Indonesia ranks second globally in tuberculosis burden, and up to 50% of treated patients develop pulmonary dysfunction. Objectives: To identify clinical and radiographic factors influencing spirometric recovery after treatment in drug-sensitive pulmonary tuberculosis. Methods: Analytical observational study with cross-sectional design. Population comprised adults (>18 years) in Medan who completed standard drug-sensitive TB therapy within six months. Sixty participants were selected by consecutive sampling. Instruments included spirometry (Global Lung Function Initiative 2022 equations) and chest radiograph scoring. A structured questionnaire captured demographics, TB history, comorbidities, and smoking. Data analysis involved bivariate tests (chi-square, Kruskal–Wallis, Fisher’s exact) and multivariate logistic regression (enter method). Results: Advanced radiographic lesion extent was the only independent predictor of abnormal spirometry (Exp(B)=4.889; 95% CI 1.386–17.241; p=0.014). Other variables lost significance after adjustment. Conclusion: Initial lesion burden on chest radiograph strongly determines pulmonary function recovery post-treatment. Early stratification by lesion extent is recommended for targeted follow-up and rehabilitation
Co-Authors Abdullah, Muntasir Adida, Fiony Amin Soebandrio Andika Pradana Anhar, Taufik Aritonang, Minarni ES. Bayani, Sri Damanik, Rizki amaliah Dangana, Amos Erna Mutiara Eyanoer, Putri C. Firdaus, Ruby Fotarisman Zaluchu, Fotarisman Hutabarat, Eva Susanti Debora Jefri, Budi Kusumawati, R. Lia Lingga, Elfia Damaiyanti Br Listyoko, Aditya S. Listyoko, Aditya Sri Maryaningsih, Maryaningsih Miranda, Melly Monica, Nanda S. Osakue, Osareniro E. Pohan, Indah TS. Putri Chairani Eyanoer, Putri Chairani Raffael, Frans Ramadhani, Adini Arifah Rhinsilva, Ella Rina Amelia Rina Yunita Sebayang, Risa RB. Sembiring, Rosita J. Sihombing, Benny Simanjuntak, Donal Anjar Simbolon, Novery Sinaga, Bintang YM. Sinaga, Sudirman P. Sinaga, Sudirman Parningotan Tarigan, Amira P. Tarigan, Amira Permatasari Taufik Ashar Triwahyudi, Bibit Vera, Yeni Wahyuni, Arlinda S. Wijanarko, Wahyu Yamamoto, Zulham Zulkarnain Zulkarnain