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All Journal Molecular and Cellular Biomedical Sciences (MCBS) Majalah Kedokteran Nusantara The Journal Of Medical School Buletin Farmatera Manuju : Malahayati Nursing Journal International Journal of Nursing and Health Services (IJNHS) Sumatera Medical Journal Jurnal Kesehatan Ilmiah Indonesia / Indonesian Health Scientific Journal Journal of Telenursing (JOTING) Jurnal Aisyah : Jurnal Ilmu Kesehatan SCRIPTA SCORE Scientific Medical Journal Indonesian Journal of Global Health research Cermin Dunia Kedokteran The Journal of Society Medicine (JSOCMED) Media Dermato-Venereologica Indonesiana Journal of General Procedural Dermatology and Venereology Indonesia Cermin Dunia Kedokteran
Putra, Imam Budi
Department Of Dermatology And Venereology, Faculty Of Medicine, Universitas Sumatera Utara, Medan
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Comparison of Adiponectin Levels in Patients with Familial and Non-Familial Keloid History Finarsih ES, Ella; Putra, Imam Budi; Wardani, Meidina Kesuma
Journal of Society Medicine Vol. 4 No. 1 (2025): January
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i1.188

Abstract

Introduction: Keloid is an abnormal wound healing condition influenced by various factors, including adiponectin levels and genetic predisposition. The role of adiponectin in keloid formation, particularly concerning familial and non-familial history, remains unclear. This study aims to compare adiponectin levels in keloid patients with and without a familial history of keloid formation. To compare adiponectin levels in patients with familial and non-familial keloid history. Methods: This observational analytic study utilized a cross-sectional design involving 40 keloid patients. Participants underwent anamnesis, dermatological examination, and blood sampling to measure serum adiponectin levels using enzyme-linked immunosorbent assay (ELISA). Data were analyzed descriptively using IBM SPSS Statistics version 21. Results: Keloid was more frequently observed in female patients, particularly in the 18–25-year age group. The mean serum adiponectin level among all participants was 11.01±8.34 μg/ml. In patients with a familial history of keloid, 40.0% had low adiponectin levels, while 42.5% of those without a familial history also exhibited low levels. Statistical analysis revealed no significant difference in adiponectin levels between the two groups, suggesting that low adiponectin levels are a common feature in keloid patients regardless of genetic predisposition. Conclusion: Low adiponectin levels are prevalent among keloid patients, but they are not significantly associated with a familial history of keloid formation. Further research is needed to explore the mechanisms linking adiponectin to keloid development.
The Role of Herbal Medicine for Hypertrophic Scars Management Mendrofa, Ira; Putra, Imam Budi
Journal of Society Medicine Vol. 4 No. 1 (2025): January
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i1.191

Abstract

The process of wound healing is intricate, involving highly coordinated and synchronized mechanisms. Deviations from normal physiological responses can result in hypertrophic scarring. In recent years, there has been a global resurgence of interest in herbal remedies. Many plant-derived compounds and extracts have demonstrated the capacity to inhibit hypertrophic scar formation. The primary mode of action involves inhibiting proliferation and/or triggering apoptosis in scar fibroblasts by modulating various pathways, including PI3K/AKT, VEGF, and TGF-Beta/SMAD. Advancing our comprehension of hypertrophic scar pathophysiology, conducting follow-up research, and pursuing future investigations will help overcome current challenges and lead to the development of promising therapeutic approaches.
Vitamin D sebagai Terapi Adjuvan Kandidiasis Vulvovaginalis untuk Mengurangi Risiko Rekuren. Laporan Kasus Berbasis Bukti Peggy Liberty; Imam Budi Putra; Nelva Karmila Jusuf
Cermin Dunia Kedokteran Vol 49 No 7 (2022): Nutrisi - Vitamin D
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v49i7.261

Abstract

Latar belakang: Kandidiasis vulvovaginalis (KVV) merupakan infeksi yang disebabkan oleh Candida sp. terutama Candida albicans, dengan gejala pruritus, dispareunia, disuria, dan sekret vagina abnormal. Diperkirakan 75% wanita pernah mengalami 1 episode KVV dan 40-45% mengalami 2 atau lebih episode. Tingginya kejadian KVV menjadi masalah. Angka resistensi antijamur yang tinggi juga meningkatkan risiko kejadian KVV rekuren. Untuk mengatasi masalah ini, diperlukan terapi adjuvan KVV yang terbukti dapat menurunkan risiko kejadian KVV rekuren. Penggunaan vitamin D sebagai terapi adjuvan pada KVV dinilai berpotensi menurunkan risiko kejadian KVV rekuren karena sifat liposolubilitasnya yang mampu mengganggu integritas membran sel Candida albicans. Metode: Penelusuran literatur dilakukan pada 9 database berdasarkan pertanyaan klinis dengan kata kunci yang sesuai. Artikel dipilih berdasarkan kriteria inklusi dan eksklusi, kemudian dilakukan telaah kritis pada artikel terpilih untuk dinilai validitas, kepentingan, dan penerapannya. Hasil: Didapatkan 1 artikel yang memenuhi kriteria inklusi dan komponen telaah kritis. Simpulan: Vitamin D sebagai terapi adjuvan pada pengobatan KVV terbukti bermanfaat menurunkan risiko kejadian KVV rekuren. Background: Vulvovaginal candidiasis is an infection caused by Candida sp. especially Candida albicans, with symptoms include pruritus, dyspareunia, dysuria, and abnormal vaginal discharge. It is estimated that 75% women experience one episode of vulvovaginal candidiasis and 40-45% experience two or more episodes. The high prevalence of vulvovaginal candidiasis has become a problem. Antifungal resistance also increases risk to recurrent vulvovaginal candidiasis. Proven adjuvant therapy to lower risk of recurrent vulvovaginal candidiasis is needed. Vitamin D is potentially used as adjuvant therapy, indicated by its liposolubility which disrupt the integrity of Candida albicans’ cell membrane. Methods: Search of literature was conducted on 9 databases according to clinical question and appropriate keywords. Articles were selected according to inclusion and exclusion criteria, the selected articles were critically appraised for its validity, importance, and applicability. Results: One article fulfills the inclusion criteria and components of critical appraisal. Conclusion: Vitamin D as adjuvant in treatmentof vulvovaginal candidiasis is proven to lower recurrent vulvovaginal candidiasis risk.
Identification of Microbiota Causing Bromhidrosis in the Axillary Utama, Putri Wahdiah; Jusuf, Nelva Karmila; Putra, Imam Budi; Ichwan, Muhammad; Kusumawati, R. Lia
Indonesian Journal of Global Health Research Vol 7 No 1 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i1.4194

Abstract

Bromhidrosis is a clinical condition defined by an uncomfortable or unpleasant body odor. Since the apocrine glands are only active during puberty, most bromhidrosis occurs in the apocrine glands in the armpit and occurs when apocrine gland secretions approach the skin's surface, where they undergo various biochemical reactions caused by the presence of microbiota in the axillary skin, resulting in odor in the axilla. This research aims to identify microbiota species in the axilla that can cause bromhidrosis. A laboratory experimental research design with purposive sampling is used in this study. In this study, 60 samples were collected from students aged 15 to 18 years old at a high school in Medan, and the samples were analyzed at the University of North Sumatra Hospital's Microbiology Laboratory. All samples were taken from the right axillary skin swab, a Gram stain was performed, and the identified microbiota isolates were identified. The results of skin smear culture revealed a Gram-positive cocci group in 59 samples (98.3%) and a Gram-positive bacilli group in only one sample (1.7%). The microbiota responsible for bromhidrosis was identified as Staphylococcus hominis spp. hominins (30.4%), Staphylococcus epidermidis (27.8%), Staphylococcus aureus (16.5%), Kocuria kristinae and Staphylococcus haemolyticus (6.3%), Staphylococcus lugdunensis and Staphylococcus saprophyticus. The most common microbiota that causes bromhidrosis in the axilla is Staphylococcis hominis spp. Hominis, Staphylococcus epidermidis, and Staphylococcus aureus.
Gambaran Stretch Mark pada Siswi SMA Global Prima National Plus School Kamila, Rania; Putra, Imam Budi; Dalimunthe, Dina Arwina; Samosir, Fauzan Azmi Hasti Habibi; Kadri, Alfansuri
SCRIPTA SCORE Scientific Medical Journal Vol. 5 No. 1 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v5i1.11035

Abstract

ABSTRAK Latar Belakang. Stretch mark merupakan jenis skar atrofi pada kulit yang disebabkan oleh peregangan kulit yang berlebihan. Karakteristik stretch mark bervariasi tahap awal yaitu striae rubrae yang berwarna kemerahan, hingga tahap kronis yaitu striae albae, stretch mark yang halus dan berwarna putih. Prevalensi stretch mark pada populasi remaja dilaporkan berkisar antara 6% hingga 86%. Hal ini dapat terjadi diakibatkan oleh beberapa faktor sehingga gambaran stretch mark pada remaja perempuan penting diketahui. Penelitian ini bertujuan untuk mengetahui gambaran stretch mark pada siswi SMA Global Prima National Plus School. Metode. Penelitian ini merupakan penelitian deskriptif dengan desain cross-sectional study. Subjek penelitian pada penelitian ini adalah siswi kelas XII SMA Global Prima National Plus School sebanyak 47 orang yang memenuhi kriteria inklusi dengan menggunakan metode purposive sampling. Pengumpulan data dilakukan dengan menggunakan lembar penelitian yang ditanyakan langsung kepada subjek penelitian lalu dilanjutkan dengan pemeriksaan fisik pada subjek penelitian secara langsung. Hasil. Stretch mark dijumpai pada 38 siswi dari 47 siswi dengan distribusi paling banyak pada usia 17 tahun (66%) dan reponden dengan usia menarche normal (51,1%) regio stretch mark terbanyak pada regio femur (25,4%) dan jenis stretch mark terbanyak yaitu striae albae (82,5%). Kesimpulan. Secara keseluruhan, sebagian besar subjek penelitian memiliki stretch mark, dimana paling banyak dijumpai pada subjek penelitian dengan IMT kategori normal dan pada subjek penelitian dengan riwayat keluarga memiliki stretch mark. Kata Kunci: Gambaran, stretch mark, striae albae, striae rubrae.   ABSTRACT Background. Stretch mark is a a type of atrophic scar that was caused by excessive stretching of the skin. Stretch mark vary in the early stages as striae rubrae, are characterized with redness and the chronic stage, striae albae which appears white and wrinkly. The prevalence of stretch marks in the adolescent population reportedly ranged from 6% to 86%. This can occur due to several factors so that the picture of stretch marks in adolescent girls is important to know. Aim of this study is to describing stretch mark in Global Prima National Plus School high school students. Methods.This is a descriptive study with cross-sectional study design. The sample in this study were 47 students of SMA Global Prima National Plus School who met the inclusion criteria by using the purposive sampling method. Data acquired by using a research sheet that was asked directly to the research subject followed by physical examination of the research subject directly. Results. Stretch marks were found in 38 students from 47 students with the most distribution at the age of 17 years (66%) and research subject with normal menarche (51.1%) the most common location of stretch marks are in the femur region (25.4%) and the most common types of stretch marks are striae albae (82.5%). Conclusion. Overall, most of the research subjects had stretch marks, where majority of the research subjects had normal BMI with family history of stretch marks with normal BMI and in the research subjects with a family history of stretch marks. Key words: Descriptive,  Stretch mark, striae albae, straie rubrae.
PENGARUH MADU SEBAGAI TOPIKAL TERAPI TERHADAP TINGKAT KENYAMANAN KLIEN DENGAN LUKA KAKI DIABETIK Ritonga, Sukhri Herianto; Putra, Imam Budi; Ariani, Yesi
Jurnal Kesehatan Ilmiah Aufa Royhan Vol 1 No 1 (2016): Vol.1 No.1. April 2016
Publisher : Universitas Aufa Royhan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tingginya prevalensi diabetes mellitus (DM) memicu meningkatnya berbagai macam penyakit penyerta,salah satunya adalah luka kaki diabetik. Luka kaki diabetik hingga saat ini masih merupakanpermasalahan yang sulit untuk ditangani oleh tenaga medis. Tujuan penelitian ini adalah untukmengetahui pengaruh terapi madu terhadap tingkat kenyamanan pada klien dengan luka kaki diabetik.Penelitian ini dilaksanakan di Asri Wound Care Centre Medan dan di wilayah Kota Padangsidimpuanselama 28 minggu. Desain penelitian ini adalah quasi eksperiment dengan pendekatan one group pre testpost test design. Teknik sampling yang digunakan adalah consecutive sampling dengan kriteria penderitaluka kaki diabetik derajat IV dan V. Jumlah sampel dalam penelitian ini adalah 31 orang. Tingkatkenyamanan diukur dengan menggunakan comfort verbal rating scale. Rata-rata skala kenyamanansebelum intervensi adalah skala 1 dan menjadi skala 3,17 setelah intervensi. Hasil uji T Berpasangan padakenyamanan menunjukkan nilai 0,000 sehingga peneliti menyimpulkan terapi madu berpengaruh secarasignifikan pada terhadap kenyamanan. Berdasarkan hasil penelitian ini direkomendasikan agar dipelayanan kesehatan mengambil kebijakan yang mengakomodasi penggunaan madu sebagai alternatiftopical terapi dalam perawatan luka kaki diabetik.
Co-Authors Anita Yustina Annisa Astari Asrizal Asrizal Candra Meriani Damanik Cholina Trisa S Damanik, Candra Meriani Danil, Rezkyana Dhillon, Jesryn Dina Arwina Dalimunthe, Dina Arwina Finarsih ES, Ella Isma Aprita Lubis Jusuf, Nelva Karmila Jusuf, Nelva Karmila Kadri, Alfansuri Kamila, Rania Kartayana, Johan Kartayana, Johan Khairina Nasution Kusumawati, R. Lia Lubis, Ade Fitriyani Mendrofa, Ira Meutia, Nanda Muhammad Husaini Muhammad Ichwan Nasution, Siti Saidah Nelva K. Jusuf Nelva Karmila Jusuf Nelva Karmila Jusuf Nelva Karmila Jusuf Peggy Liberti Peggy Liberty Risanti, Rinda Chindra Ritonga, Sukhri Herianto Saidah Nst, Siti Samosir, Fauzan Azmi Hasti Habibi Sari, Lovena Setiawan Setiawan Setiawan, Setiawan Siti Saodah Syahputri, Fitriend Utama, Putri Wahdiah utami, dina rizki Utami, Dina Rizki Wardani, Meidina Kesuma Wiryadana, Michelle Yesi Ariani Yosie Anra Zega, Petra Diansari