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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Biosfer: Jurnal Pendidikan Biologi Bioma : Jurnal Biologi Indonesia Pendas : Jurnah Ilmiah Pendidikan Dasar Edusifa: Jurnal Pendidikan Islam Khidmatussifa: Journal of Islamic Studies Best Journal of Administration and Management Jurnal Ilmu Kesehatan dan Gizi Tasyri' Journal on Education and Teacher Professionalism Prosiding Seminar Nasional dan Call For Paper Kebidanan Universitas Ngudi Waluyo Jurnal Warna EDUCATIONE: Journal of Education Research and Review Science Techno Health Journal
Supriyatin
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Nursing Physics Public Health Social Sciences Other

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STRATEGI OPTIMALISASI MOTORIK HALUS ANAK USIA DINI MELALUI AKTIVITAS PAPER CRAFT 3M (MELIPAT, MENGGUNTING, DAN MENEMPEL) DI TK KARTINI WANGKAL Supriyatin
Pendas : Jurnal Ilmiah Pendidikan Dasar Vol. 11 No. 01 (2026): Volume 11 No. 01 Maret 2026 Publish
Publisher : Program Studi Pendidikan Guru Sekolah Dasar FKIP Universitas Pasundan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23969/jp.v11i01.41480

Abstract

Fine motor skills play an important role in early childhood learning readiness. This study aimed to optimize children’s fine motor skills through a learning strategy based on Paper Craft 3M activities (folding, cutting, and pasting). The research employed two-cycle Classroom Action Research (CAR) consisting of planning, action, observation, and reflection, involving 20 children aged 4–5 years at Kartini Wangkal Kindergarten, Probolinggo Regency. Data were collected through structured observation using a fine motor development assessment sheet. The results showed an improvement in fine motor skills, from the pre-cycle stage with no children achieving the Developing as Expected (DE) and Very Well Developed (VWD) categories, to 20% of children reaching DE in Cycle I, and a significant increase in Cycle II with 75% achieving DE and 25% achieving VWD. These findings indicate that Paper Craft 3M activities are effective in optimizing fine motor skills in early childhood.
Leaf area and stomatal density of Rhizophora mucronata Poir. under high and low light environment of Nature Tourism Park Angke-Kapuk, Jakarta, Indonesia Wibisono, Bagus Tito; Tri Wahyuni; Murniati Simanjuntak; Abizar; Supriyatin
Bioma Vol. 20 No. 2 (2024): Bioma
Publisher : LPPM Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/bioma.v20i2.49339

Abstract

Each type of mangrove has specific stomatal characteristics, one of which is stomatal density. This stomatal density is directly proportional to the rate of evaporation, transpiration, and photosynthesis which is a form of mangrove adaptation to its environment. One of the external factors affecting stomatal density is light intensity which can vary due to canopy cover. This study aims to compare the stomatal density of Rhizophora mucronata Poir. in the Angke-Kapuk area, Jakarta, Indonesia. The location is a mangrove conservation area that has experienced a lot of environmental pressure, especially due to population growth and land conversion into settlements. Descriptive methods was used with transect sampling techniques at locations that represent very open and very closed canopies determined by purposive sampling. Stomatal sampling was carried out by applying a transparent nail polish on the lower surface of the leaf and then covering it with tape. The tape was observed using a microscope, and showed that Rhizophora mucronata Poir. has a low stomatal density. The results of the parametric independent sample t-test showed that the stomatal density of Rhizophora mucronata was not significantly different between very open and very closed canopy cover.
In Silico Study of the potency of Drynaria rigidula (Sw.) Bedd. (Polypodiaceae) compounds in breast cancer therapy targeting AKT1 protein pathways Ma'arif, Naufal; Sefti Adelia; Alifia Dwinanti Hakamashe; Fadila Nur’anfa Putri; Nailul Rahmi Aulya; Supriyatin
Bioma Vol. 20 No. 2 (2024): Bioma
Publisher : LPPM Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/bioma.v20i2.49340

Abstract

Breast cancer is the second most prevalent cancer globally. One of the key pathways involved in breast cancer is the PI3K/Akt mechanism. A natural compound with potential that has not been extensively studied is Drynaria rigidula (Sw.) Bedd., a Polypodiaceous fern native to Indonesia and is commonly used in traditional medicine. This study aims to explore the potential of Drynaria rigidula as an anti-breast cancer agent. The method used in silico analysis by collecting data from several web servers such as SwissADME (https://www.swissadme.ch/) with the parameters Lipinski’s rule of five, Veber, Egan, and Way2Drug for biological activity. The protein used in this study is AKT1 (PDB ID: 6HHF), obtained from the RCSB database. Molecular docking analysis was conducted using PyRx software with visualization performed in Biovia Discovery Studio. The results showed that several compounds, such as 3,4-dihydroxybenzoic acid, fern-9(11) ene, Stigmasterol, dan Campesterol, had RMSD values < 3.0 Å and binding affinities of -9.4, -9.2, -7.6, and -7.6 respectively. These results were compared with the control ligand AZD5363 and doxorubicin, which had a binding affinity from each other are -8.3 and -7.4. Therefore, the docking results indicate that compounds from Drynaria rigidula are predicted to have potential as anti-cancer agents.
Co-Authors Abizar Ahmad Sofyan Ahmad Sofyan Alifia Dwinanti Hakamashe Arifah Siti Dinah Daiyatul Falah Fadila Nur’anfa Putri Fadillah, Taufik Ismail Faros, Arrum Ardila Fatimatuz, Farida Fitriasih, Fajarani Hapsari Windayanti Hery Prambudi Indiya Gilang Ingkwi Sohogono Husuwi Isriyah, Mudafiatun Jayawarsa, A.A. Ketut kaimudin Kaimudin, Kaimudin Laeli Mufarikhah Ma'arif, Naufal Misno Misno, Misno Mufarikah, Lailiyatul Murniati Simanjuntak Nailul Rahmi Aulya Nana Mulyana Neni Ratna Nur Khasanah Nur Khasanah Savitriani Nuryati Qori Amarullah, Risal Rahmawati, Weni Kurnia Ratna Komala, Ratna Ratna, Neni Sefti Adelia Siti Nurhayati Solikhah SRI RAHAYU Sunaryati, Nani Supenah, Pipin Titus Tambaip Tri Wahyuni Wibisono, Bagus Tito Widayati Wulandari Retnaningrum Yanuar, Rizki Aditya Zaenal Abidin