Article Per Year (5 Year)
p-Index From 2021 - 2026
3.146
P-Index
This Author published in this journals
All Journal E-Jurnal Medika Udayana JOPS (Journal Of Pharmacy and Science) JURNAL KESEHATAN PERINTIS Health and Medical Journal Andalas obstetrics and gynecology journal Jurnal Abdi Insani jurnal abdimas saintika Nusantara Hasana Journal Scientific Journal Jurnal Pengabdian Masyarakat Bangsa AMMA : Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Kesehatan (JURABDIKES) Journal of Public Health Science (JoPHS) Frontiers on Healthcare Research
liana, nana
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

Published : 23 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 23 Documents
Search

 1   2   3 
Skrining Tekanan Darah, Gula Darah, dan Status Gizi sebagai Upaya Pencegahan Penyakit Kronis di Masyarakat Oktora, Meta Zulyati; Anggraini, Debie; Haiga, Yuri; Liana, Nana; Nurwiyeni; Putriyuni, Anandia; Aliefia, Desi
Abdika Sciena Vol 3 No 1 (2025): JURABDIKES Volume 3 No 1, Juni 2025
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/jurabdikes.v3i1.219

Abstract

Latar Belakang: Penyakit tidak menular (PTM) seperti hipertensi, diabetes mellitus, dan dislipidemia merupakan penyebab utama morbiditas dan mortalitas di Indonesia. Deteksi dini melalui pemeriksaan kesehatan komunitas merupakan langkah strategis untuk mencegah komplikasi jangka panjang dan meningkatkan kesadaran masyarakat terhadap pentingnya gaya hidup sehat. Tujuan: Kegiatan pengabdian ini bertujuan untuk melakukan deteksi dini faktor risiko PTM dan memberikan edukasi kesehatan kepada masyarakat Nagari Sagalo, Kabupaten Pesisir Selatan. Metode: Kegiatan dilaksanakan pada bulan Agustus 2024 dalam bentuk pemeriksaan kesehatan massal oleh tim KKN terpadu. Parameter yang diperiksa meliputi tekanan darah, kadar gula darah, berat badan, tinggi badan, dan status lansia. Edukasi mengenai pencegahan PTM dan gaya hidup sehat diberikan secara langsung melalui penyuluhan dan media cetak. Data hasil pemeriksaan dianalisis secara deskriptif. Hasil: Rata-rata berat badan peserta adalah 54,9 kg dengan kisaran 29,5–85,2 kg. Tinggi badan rata-rata 148,9 cm. Rata-rata tekanan darah sistolik sebesar 129,4 mmHg dan diastolik 76,8 mmHg. Kadar gula darah rata-rata 110,8 mg/dL dengan nilai tertinggi mencapai 162 mg/dL. Ditemukan beberapa peserta dengan tekanan darah dan kadar gula di atas ambang normal, yang belum menyadari status kesehatannya sebelumnya. Kesimpulan: Kegiatan deteksi dini ini berhasil mengidentifikasi individu dengan faktor risiko PTM yang belum terdiagnosis. Pemeriksaan komunitas dan edukasi kesehatan terbukti penting untuk meningkatkan kesadaran masyarakat terhadap pencegahan penyakit kronis. Disarankan dilakukan tindak lanjut berupa pembinaan dan pemantauan kesehatan secara berkala.
Subtipe Histopatologis Adenokarsinoma Kolorektal Berdasarkan WHO : Implikasi Terhadap Prognosis Liana, Nana; Setiawati, Yessy; Ruhsyahadati; Triyana, Rahma; Helmizar, Roland
Scientific Journal Vol. 4 No. 3 (2025): SCIENA Volume IV No 3, May 2025
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v4i3.209

Abstract

Adenokarsinoma kolorektal merupakan tipe histologis paling umum dari kanker kolorektal yang menunjukkan heterogenitas morfologis dan biologis yang tinggi. Variasi ini memengaruhi tidak hanya pola penyebaran dan respons terhadap terapi, tetapi juga prognosis pasien secara keseluruhan. Klasifikasi histopatologi yang ditetapkan oleh World Health Organization (WHO) memberikan pedoman sistematis dalam membedakan berbagai subtipe adenokarsinoma kolorektal, seperti adenokarsinoma konvensional, mucinous, signet-ring cell, dan medullary carcinoma. Subtipe-subtipe ini diketahui memiliki perbedaan signifikan dalam perilaku klinis dan sensitivitas terhadap pengobatan. Oleh karena itu, pemahaman dan penerapan klasifikasi WHO sangat penting untuk meningkatkan akurasi diagnosis, perencanaan terapi yang tepat sasaran, serta prediksi prognosis yang lebih akurat. Tujuan penulisan ini adalah untuk menyoroti pentingnya klasifikasi histopatologi WHO dalam menunjang pengambilan keputusan klinis terkait terapi dan prognosis pasien dengan adenokarsinoma kolorektal.
DIAGNOSTIC HISTOPATHOLOGY OF JUVENILE GRANULOSA CELL TUMOR: HALLMARK MORPHOLOGICAL AND CYTOLOGICAL FINDINGS Liana, Nana; Ruhsyahadati, Ruhsyahadati; Triyana, Rahma; Helmizar, Roland; Dhuha, Alief; Malik, Rifkind; Saputra, Muhammad Rizki
Nusantara Hasana Journal Vol. 4 No. 12 (2025): Nusantara Hasana Journal, May 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v4i12.1417

Abstract

Juvenile granulosa cell tumour (JGCT) is a subtype of granulosa cell tumour that predominantly affects young females, particularly those who are premenarchal, with a mean age at diagnosis of 13 years. Although rare, this tumour can occur across a wide age range, from 10 months to 67 years. Histologically, JGCT resembles the adult-type granulosa cell tumour but presents with distinct features, including aggressive growth and the absence of FOXL2 mutations. Common clinical manifestations include an abdominal mass, abdominal pain, precocious puberty in prepubertal girls due to estrogen secretion, and menorrhagia or amenorrhea in premenopausal women. Macroscopically, the tumour typically exhibits a dominant solid component, frequently accompanied by hemorrhagic and necrotic areas. High mitotic activity and variable degrees of cytological atypia are characteristic findings. The diagnosis is supported by positive immunoreactivity for inhibin, calretinin, and CD99. In early-stage disease, the primary treatment is unilateral oophorectomy with fertility preservation. In contrast, advanced stages often require total hysterectomy and adjuvant chemotherapy. Prognosis is highly dependent on disease stage; patients with stage I disease have a survival rate of up to 97%, whereas advanced-stage disease is associated with a poorer outcome. This review aims to provide a comprehensive overview of the epidemiology, pathogenesis, clinical manifestations, diagnostic approaches, and management strategies of Juvenile Granulosa Cell Tumour (JGCT). It also underscores the importance of early detection and the development of more effective therapeutic options to enhance clinical outcomes.
MEKANISME PENSINYALAN VASCULAR ENDOTHELIAL GROWTH FACTOR DALAM PERKEMBANGAN DAN PENYEBARAN KANKER Liana, Nana; Helmizar, Roland; Ruhsyahadati, Ruhsyahadati; Triyana, Rahma; Saputra, Muhammad Rizki
Nusantara Hasana Journal Vol. 5 No. 3 (2025): Nusantara Hasana Journal, August 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i3.1598

Abstract

Vascular Endothelial Growth Factor (VEGF) is a key mediator in the process of angiogenesis, playing a crucial role in the development and spread of malignant tumors. VEGF consists of several isoforms, primarily VEGF-A, which exert their effects through receptors VEGFR-1, VEGFR-2, and VEGFR-3, as well as co-receptors neuropilin-1 and -2. Activation of VEGF signaling pathways stimulates endothelial cell proliferation, migration, and survival, increases vascular permeability, and facilitates the formation and invasion of tumor-associated blood vessels. VEGF expression is regulated by various factors, including hypoxia via HIF-1α activation, oncogenes such as KRAS and Src, and the suppression of tumor suppressor genes such as p53 and PTEN. Additionally, several growth factors including EGF, PDGF, and IGF contribute to the regulation of VEGF. VEGF signaling also promotes tumor invasion by activating proteolytic enzymes such as MMP-2, MMP-9, and uPA, which degrade the basement membrane. Due to its central role in angiogenesis and tumor invasion, VEGF is a strategic target in anti-angiogenic therapies for various types of cancer. A comprehensive understanding of the structure, function, and regulation of VEGF is essential for the development of more effective molecular therapies.
PROFIL RESPIRATORY DISTRESS PADA BAYI BARU LAHIR DI NICU RSIA SITI HAWA PADANG TAHUN 2021 Eldrian, Febiane; Liana, Nana; Aditia Permana, Yudhi; Lismawati; Helmizar, Roland
Nusantara Hasana Journal Vol. 3 No. 12 (2024): Nusantara Hasana Journal, May 2024
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v3i12.1121

Abstract

Respiratory distress (RD) poses a significant issue that can lead to fatal consequences such as respiratory failure, brain damage, and an increase in morbidity and mortality among newborns. The diagnosis of RD is based on the identification of one or more signs of increased respiratory activity, including tachypnea, nasal flaring, retractions in the intercostal area, and grunting. Objective: The purpose of this research is to provide an overview of the occurrence of RD among neonatus who were hospitalized in the Neonatal Intensive Care Unit (NICU) at RSIA Siti Hawa Padang in the year 2021. Methods: This study is an analytic descriptive research. The accessible population in this study consists of newborns who were treated at the NICU of RSIA Siti Hawa Padang during the year 2021. Results: From the study findings, it was observed that 94 newborns (approximately 5.2%) experienced RD. Among them, males were more predominant, accounting for 54 infants (57%). The majority of infants had a gestational age categorized as full-term, totaling 56 infants (59.6%). Furthermore, the birth weight for the majority of newborns was within the normal range, with 65 infants (69.1%) falling into this category. Conclusion: In conclusion, the majority of newborns at NICU RSIA Siti Hawa Padang in 2021 did not experience RD. Among those affected by RD, males were predominant, and most had a gestational age categorized as full-term, indicating a low risk of prematurity. The average birth weight also tended to be within the normal range for newborns born and cared for in NICU RSIA Siti Hawa Padang in 2021.
THE PROFILE OF COLORECTAL ADENOCARCINOMA AT DR. M. DJAMIL GENERAL HOSPITAL PADANG, INDONESIA Liana, Nana; Helmizar, Roland; Ruhsyahadati, Ruhsyahadati; Jelmila, Sri Nani; Triyana, Rahma; Lismawati, Lismawati
Nusantara Hasana Journal Vol. 4 No. 1 (2024): Nusantara Hasana Journal, Juny 2024
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v4i1.1132

Abstract

Colorectal carcinoma is the third most common malignancy in the world. This malignancy originates from the epithelium of the colon and/or rectum, showing glandular or mucinous differentiation, where tumor cells have penetrated the muscularis mucosae layer. The study aims to report on epidemiological, clinical, and pathological characteristics of colorectal adenocarcinoma. Methods: We performed a retrospective descriptive study of 140 cases of colorectal adenocarcinoma in the gastroenterology and general surgery departments of M. Djamil General Hospital Padang, Indonesia conducted from January 2022 to December 2022. Data collection using medical records of patients in M. Djamil General Hospital Padang, Indonesia. We reported different data: Age, sex, site, and differentiation grade of the tumor. Results: Our study included 140 patients 80 males (57,1%) and 60 females (42.9%), with a median age range of 51-60 years. The tumors were found in the rectum 82 (58.6%), distal colon 37(26.4%), and proximal colon 21(15.0%). The differentiation grade was majority low grade 117 (83.6%). Conclusion: In conclusion, our result showed that colorectal adenocarcinoma is highest in the male population with an age range of 61-70 years. The most common site of adenocarcinoma is rectum. A low grade is the most differentiated grade. Keywords: colorectal adenocarcinoma, anatomical location, differentiation grade, profile
Transformasi Teratoma Matur Mediastinum Menjadi Mucinous Adenocarcinoma Disertai Sitologi Sikatan Bronkus Positif Liana, Nana; Yenita, Yenita
Health and Medical Journal Vol 5, No 2 (2023): HEME May 2023
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v5i2.1281

Abstract

Pendahuluan: Teratoma matur adalah germ cell tumor yang paling banyak ditemukan di mediastinum yaitu 50-70%. Namun kejadian transformasi keganasan non germ cell masih sangat jarang hanya sekitar 6% dari germ cell tumor. Laporan Kasus: Kami melaporkan kasus pasien perempuan usia 43 tahun datang dengan keluhan sesak nafas dan massa kistik multilokular di mediastinum anterior. Pasien menjalani tindakan torakotomi eksplorasi dan eksisi tumor dengan diagnosis histopatologi teratoma matur. Sepuluh bulan setelah operasi pasien datang dengan benjolan baru di suprasternum. Biopsi massa di suprasternum menunjukkan metastasis mucinous carcinoma. Pemeriksaan CT-Scan toraks tampak adanya pulmoner metastase dari tumor mediastinum anterior (residif). Pada sitologi sikatan bronkus juga ditemukan metastase mucinous adenocarcinoma. Setelah dilakukan review pada sediaan awal ditemukan fokus mucinous adenocarcinoma dalam teratoma matur mediastinum dan radang granulomatosa ekstensif yang menandakan ruptur kista. Kesimpulan: Teratoma matur dapat mengalami transformasi keganasan dari komponen non germ cell. Untuk mengetahui asal komponen mucinous adenocarcinoma dibutuhkan pemeriksaan imunohistokimia CK7, CK20 dan TTF1. Pada kasus ini didapatkan CK7 positif, CK 20 negatif dan TTF1 negatif, sehingga disimpulkan komponen mucinous adenocarcinoma berasal dari teratoma matur di mediastinum yang mengalami transformasi keganasan
Extra Gastrointestinal Stromal Tumor Pada Ovarium, Kasus Jarang Liana, Nana; Nizar, RZ; Asri, Aswiyanti; Novianti, Hera; Friadi, Andi
Andalas Obstetrics And Gynecology Journal Vol. 4 No. 2 (2020)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.2.173-182.2020

Abstract

Objective : This article objective is to describe a woman with extra gastrointestinal stromal tumor (extra GIST) in ovary; Method : A case report and literature review; The author reports a woman 54 years old with complaints of swelling in the abdomen. Tumors suspected originate from ovary with an extension to abdominal wall. The patient had history of previous ovarian tumor surgery with pathological anatomy diagnosis was thecoma. Working diagnosis of the patient was residif ovarian malignancy and then suboptimal debulking was performed. Microscopically, ovarian tumors appear cellular and diffuse, partially arranged fascicles. Cells with rounded-spindle nuclei, mitosis ≥ 4 per 10 HPF. The conclusion was malignant thecoma which metastasizes to peritoneum and omentum. Differential diagnosis were GIST and leiomyosarcoma. Immunohistochemistry examination was performed with  Calretinin and CD117 to rule out the differential diagnosis. Calretinin were negative  and CD117 were strongly positively smeared. Based on the morphology and positive CD117 results, diagnosis was extra GIST of ovary.; Conclusion: Extra GIST in the ovary is an unusual location so that it can be misdiagnosed as a gynecological disorder. The differential diagnosis at this location is quite limited including thecoma, fibrothecoma and leiomyosarcoma.Keywords: extra gastrointestinal stromal tumor, ovary, thecoma
Deteksi Dini Kanker Serviks dan Edukasi Kegunaan Pemeriksaan Pap Smear Liana, Nana; Nurwiyeni; Zulyati Oktora, Meta; Putriyuni, Anandia
AMMA : Jurnal Pengabdian Masyarakat Vol. 2 No. 4 (2023): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cervical cancer is the second largest malignancy after breast cancer in Indonesia. The incidence is increasing every year. In the United States and several other countries, the incidence of cervical cancer has decreased due to public health services and lifestyle changes as well as early implementation through pap smears. In developing countries, the mortality and incidence of cervical cancer has also decreased by 34-80% in the last 50 years. This is sufficient because the period of occurrence of cervical cancer is long and 90-95% of pathological changes in the epithelium can be determined through the Pap smear test. However, in developing countries, health services are still limited and there are no screening programs, cervical cancer is still the leading cause of death in women. Cervical cancer is often diagnosed at an advanced stage and the survival rate is low. On the other hand, the cure rate for early cervical cancer is very high. Therefore, it is important for women to undergo regular pap smears test so that the health condition of the cervix can be monitored and cervical cancer can be detected early.
EDUKASI EFEK PENGGUNAAN GAWAI TERHADAP KESEHATAN TUBUH DAN MENTAL Ruhsyahadati; Liana, Nana; Tri Yana, Rahma; Susanti, Melya; Helmizar, Roland; Nani Jelmila, Sri; Puspita, Dian; Tri Septiana, Vina
Jurnal Abdi Insani Vol 11 No 3 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i3.1650

Abstract

The integration of gadgets into daily life has become unavoidable, especially among children and teenagers. These devices offer numerous advantages, such as facilitating access to information and communication. However, overuse can harm physical and mental well-being. Studies have shown that excessive gadget use can cause posture issues, eye strain, obesity, and developmental problems both psychologically and socially in young individuals. To combat these negative effects, the Faculty of Medicine at Baiturrahmah University in Padang organized an educational initiative at the Babussalam Muhammadiyah Mosque. This program, aimed at elementary school students in a Ramadan boarding school, utilized interactive presentations, discussions, and quizzes to educate participants about responsible gadget use. Thirty-five students aged 10-13 attended, showing improved understanding of the adverse effects of gadget overuse and learning tips for maintaining eye health and proper posture. The students were highly engaged and appreciated the information. Overall, educating young people about the implications of gadget use enhances their awareness and promotes healthier usage habits, mitigating potential health risks.
Co-Authors A, Meridha Mutiara Adelin, Prima Aditia Permana, Yudhi Ajisman, Ruhsyahadati Aliefia, Desi Amanah Fauziah, Suci Andi Friadi Anggraini, Debie Angraini, Desti Arifa, Nurwahidatul Aswiyanti Asri Dhuha, Alief Dian Puspita Eldrian, Febiane Erlina Rustam Ferdian, Arif Gestina Aliska Haiga, Yuri Hasni, Dita Helmizar, Roland Jelmila, Sri Nani Lismawati Lismawati, Lismawati Malik, Rifkind Melya Susanti Miming Andika Muhammad Rizki Saputra, Muhammad Rizki Nani Jelmila, Sri Nizar, RZ Nova, Riki Novianti, Hera Nurwiyeni Oktora, Meta Zulyanti Oktora, Meta Zulyati Oktora, MetaZulyati Putriyuni, Anandia Rasyid, Lismawati Reza, Tia Riyada, Fauziatul Ruhsyahadati Ruhsyahadati, Ruhsyahadati Setiawati, Erdanela Setiawati, Yessy Suharni Suharni Tasya, Cerint Iralloza Tri Septiana, Vina Tri Yana, Rahma Triyana, Rahma Yahdian Rasyadi Yenita . Yesika, Relin Yurizali, Bun Zulyati Oktora, Meta