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Maulana, Sidik
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Mpox, HIV infection, and genital skin disease: triple burden, threats and challenges from an epidemiological perspective Adnyana, I Made Dwi Mertha; Eljatin, Dwinka Syafira; Maulana, Sidik; Ibrahim, Kusman; Umar, Tungki Pratama; Armini, Luh Nik; Cruz, Zito Viegas da
Svāsthya: Trends in General Medicine and Public Health Vol. 1 No. 1 (2024): July 2024
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v1i1.1

Abstract

The expansion and transformation of Mpox (MPX) disease alongside HIV and genital skin diseases has led to an increase in global morbidity and mortality in a relatively brief period. These diseases have a similar transmission pathway through sexual intercourse (mainly MSM/men-sex with males). This review aims to provide a concise, evidence-based overview of MPX, HIV, and genital skin disease coinfections, and to identify epidemiological threats and challenges. Our investigations revealed that from January 2022 to July 2023, there was a significant increase in the number of MPX cases, which reached a total of 88,600, resulting in 152 deaths across 113 countries. There have been case reports of triple-burden disease in six different areas of the world, with at least 52% of reported cases occurring in men who have had sexual activity with other men, 84.1% of whom do not use condoms and do not take pre-exposure prophylaxis (PrEP). In addition, the highest number of deaths due to co-infection with MPX, HIV infection, and genital skin diseases occurred in vulnerable groups (LGBTQIA2S+), especially in men who had sex with men, up to 90.9%, and experienced an increase in the frequency of triple burden diseases to 104.9%. From an epidemiological standpoint, this condition generates several threats and challenges, including an increasing burden of infectious diseases, an increase in immunocompromised populations, an increase in overlapping risk factors, diagnostic difficulties, an increase in interactions and comorbidities, and relatively complex treatment challenges. To suppress these outbreaks and pandemics, comprehensive control and prevention should be proposed collaboratively, including collaboration with the education sector to conduct better research and investigation using one health in complex settings. Epidemiological modeling can be used in the future to accelerate the control of these diseases.
Raising the flag of vigilance on Mpox outbreak in Indonesia: are we prepared? Adnyana, I Made Dwi Mertha; Maulana, Sidik; Lutfian, Lutfian; Adiwinoto, Ronald Pratama
Svāsthya: Trends in General Medicine and Public Health Vol. 1 No. 2 (2024): September 2024
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v1i2.63

Abstract

In the wake of the COVID-19 pandemic, the world has become acutely aware of the devastating impact of infectious diseases on public health, economies, and societies. As we gradually recover from the aftermath of COVID-19, another potential threat looms on the horizon, mpox, formerly known as monkeypox. The recent surge in mpox cases worldwide has prompted health authorities to sound an alarm, and Indonesia, as a populous nation with a complex healthcare system, must ask itself: Are we prepared for this emerging challenge?. The question "Are we prepared?" may not have a simple yes or no answer. Instead, it should serve as a reminder of the need for vigilance, adaptation, and continuous improvement in public health systems. As we navigate this new health challenge, the true measure of Indonesia's preparedness is its ability to respond swiftly, effectively, and equitably to protect the health and well-being of all citizens.
Co-Authors Adnyana , I Made Dwi Mertha Ahmad Soleh Alamsyah , Alif Novliyan Amirah, Shakira Cruz, Zito Viegas da Dwi Puji Lestari, Dwi Puji Dwinka Syafira Eljatin Gartika, Nina Gatot Pramuhadi Gayatri, Ida Ayu Made Ermeytha Hana Rizmadewi Agustina Hijeria, Putri Iqbal Pramukti Jabareen, Raifa Khairunnisa, Najwa Nisriina Kholilurahman, Dede Kosim Kosim Kurniawan Kurniawan Kusman Ibrahim Laili Rahayuwati Luh Nik Armini Lutfian, Lutfian Mago, Arpit Maria komariah Michael MB Kilikily, Rayen Devid Musthofa, Faizal Nita Fitria Qadous, Shurouq Ghalib Racmi, Seci Lia Ramadani, Regina Cahya Ristina Mirwanti, Ristina Ronald Pratama Adiwinoto Suwarni Suwarni Tito Irwanto, Tito Tohadi Tohadi Umar, Tungki Pratama Wagini Wagini, Wagini Yovita Hartantri Zanaya, Khaeliza Putri