Article Per Year (5 Year)
p-Index From 2021 - 2026
4.269
P-Index
This Author published in this journals
All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Pijar MIPA Jurnal Farmasi Sains dan Praktis Prosiding University Research Colloquium Jurnal Farmasi Klinik dan Sains Jurnal Pengabdian Masyarakat (Jupemas)
Rahayu, Titi Pudji
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health

Published : 33 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 33 Documents
Search

 1   2   3   4 
Formulation and Physical Evaluation of Papaya Leaf (Carica papaya L.) Ethyl Acetate Fraction Cream Preparation as Anti Acne Against Propionibacterium acne Bacteria Farda, Zais; Rahayu, Titi Pudji; Kiromah, Naelaz Zukhruf Wakhidatul
Jurnal Pijar Mipa Vol. 19 No. 2 (2024): March 2024
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v19i2.6146

Abstract

Acne or acne vulgaris is a disease in the form of inflammation of multiple sebaceous glands caused by the bacteria Propionibacterium acne. Papaya leaves are a plant that can potentially be used as an acne treatment. To determine the antiacne activity of papaya leaf ethyl acetate fraction cream preparations caused by Propionibacterium acne bacteria. The ethyl acetate fraction of papaya leaves are made into a cream preparation with varying concentrations of ten, fifteen, and twenty percent. The results of the cream preparation test met the physical property standards. Still, the viscosity in formulation three did not meet the standards, and formulas two and three did not meet the cream stability test standards. Antibacterial tests show that all formulas have inhibitory power against bacteria. The average inhibition zone results in formula one, formula two, and formula three were 4.99 ± 0.48 mm, 6.85 ± 0.48 mm and 10.12 ± 1.42 mm. Formula One papaya leaf fraction cream fulfills all the physical characteristics of the preparation. All papaya leaf ethyl acetate fraction cream preparations are antibacterial against Propionibacterium acne. So, research can be developed using the ethyl acetate fraction of papaya leaves in various preparations, and activity tests against other bacteria can be carried out.
FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN MASKER CLAY EKSTRAK METANOL DAUN MANGGA ARUM MANIS (Mangifera indica L.) TERHADAP Propionibacterium acnes Wati, Iis Rizki; Rahayu, Titi Pudji; Fitriyati, Laeli
Jurnal Farmasi Klinik dan Sains Vol 3, No 1 (2023): Jurnal Farmasi Klinik dan Sains
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Gombong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26753/jfks.v3i1.965

Abstract

Masalah pada kulit wajah salah satunya yaitu jerawat. Jerawat dapat disebabkan oleh bakteri Propionibacterium acnes. Tanaman daun mangga arum manis merupakan tanaman yang banyak tersebar di Indonesia dengan kandungan flavonoid yang memiliki potensi sebagai antijerawat. Masker clay merupakan sediaan masker yang paling populer dibandingkan sediaan masker lainnya. Penelitian ini bertujuan untuk mendapatkan formula sediaan masker clay ekstrak metanol daun mangga arum manis yang memiliki karakteristik baik dan efektif sebagai antijerawat. Penelitian ini membuat 3 formula sediaan masker clay menggunakan zat aktif ekstrak metanol daun mangga arum manis dengan konsentrasi formula yang berbeda F1 (10%), F2 (15%), dan F3 (20%). Sediaan masker clay ekstrak daun mangga arum manis dilakukan karakteristik fisik sediaan dan diujikan aktivitas antibakterinya terhadap Propionibacterium acnes dengan mengukur zona hambat yang terbentuk. Metode antibakteri yang digunakan merupakan metode sumuran. Hasil menunjukkan bahwa semua sediaan masker clay ekstrak metanol daun mangga arum manis mempunyai karakteristik sediaan, kecuali formula 3 tidak memenuhi viskositas sediaan. Variasi konsentrasi ekstrak metanol daun mangga arum manis mempengaruhi karakteristik sediaan dengan hasil one way annova p<0.05. Hasil uji antibakteri menunjukkan bahwa ketiga formula memiliki aktivitas antibakteri terhadap Propionibacterium acnes dengan diameter zona hambat berturut-turut adalah 9,21 mm, 9,63 mm, dan 11,06 mm. Hasil uji antibakteri ketiga formula sediaan masker clay ekstrak metanol daun mangga arum manis memiliki aktivitas antibakteri pada formula 1 dan 2 dengan kategori sedang dan formula 3 dengan kategori kuat. Semua formula sediaan masker clay ekstrak daun mangga memenuhi persyaratan mutu sediaan dan mempunyai aktivitas antibakteri.
In Vivo Identification of the Iron-Chelating Potential of Kwini Mango (Mangifera odorata Griff) Leaf Extract in Iron Overload Cases Rahayu, Titi Pudji; Yuliani, Sapto; Susanti, Hari; Supriyanto, Sugeng; Indratmoko, Septiana
Jurnal Penelitian Pendidikan IPA Vol 11 No 5 (2025): May
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i5.11180

Abstract

Iron overload (IO) is a condition characterized by an abnormal accumulation of iron in the body, which affects vital organs such as the liver, heart, pancreas, and endocrine tissues. Kwini mango (Mangifera odorata Griff) leaves, which contain mangiferin (a phenolic compound), have the ability to chelate Fe3+ by promoting the oxidation of Fe2+, potentially lowering blood iron levels. This study aimed to explore the potential of kwini mango leaf extract (KMLE) as an in vivo iron chelator for treating IO, using blood samples from an IO patient. The in vivo study assessed the effects of KMLE on ferritin, SGPT, SGOT, BUN, creatinine, and serum hematology levels in blood samples. Additionally, liver and kidney histopathology were examined as markers of iron chelation. The extract's standardization was performed to determine the mangiferin content in KMLE. The in vivo results showed a decrease in ferritin, SGPT, SGOT, BUN, creatinine, and hematological parameters. Comparisons between the KMLE group, deferoxamine group, and mangiferin group indicated a significant reduction in ferritin levels in both the deferoxamine and mangiferin groups when compared to the KMLE group at doses of 50 mg/200 g BW and 100 mg/200 g BW (Asym. Sig. (2-tailed) < 0.05). A similar pattern was observed for reductions in SGPT, SGOT, BUN, and creatinine levels at the same doses (Asym. Sig. (2-tailed) < 0.05). No significant difference was observed in the KMLE group at a dose of 200 mg/200 g BW (Asym. Sig. (2-tailed) > 0.05). KMLE demonstrates the potential to reduce serum ferritin, SGOT, SGPT, BUN, creatinine, and improve liver histopathology, suggesting its effectiveness as an iron chelator for treating IO.
Co-Authors Ainni, Ayu Nissa Anggraeni Eka Puspitasari Anwar Sodik, Anwar Arsyad, Fitdyah Al Ridha Dewi, Rahmatia Candra Ery purwanti Fajrian, Zesi Oktina Nur Farda, Zais Fatimah, Ayu Fitriyati, Laeli Fitriyati, Laely Handayani, Eka Wuri Hari Susanti Herniyatun, H Huluk, Muhammad Husnul Intiyani, Rafila Khuluq, Husnul Khuluq, Muh.Husnul Khuluq, Muhammad Husnul Kinanti, Ayu Pratama Kiromah, Naelaz Zukhruf Wakhidatul Kiromah, Naelaz Zukruf Wakhidatul Kumalasari, Siska Melisa, Leni Mulyana, Satria Eta Mulyani, Ayu Achiriyah Najah, Azka Barokatun Ningsih, Eka Ratna Pamungkas, Anindya Arya Pratiwi, Noviani Pravitasari, Rokhania Eka Putri Amalia Putri, Ferlia Setianifah Rachmawati, Indah Raharjo, Rahmat Budhi Riantika, Sabrina Safitriyani, Riyan Eka Nurul Sapto Yuliani Septiani, Sinta Wahyu Siti Khoiriah Sugeng Supriyanto Supriyanto, Sugeng Tangawuningsih, Asriani Utomo, Hijan Dzulfadhli Wahyu Rahmatulloh Wahyuni, Septi Wati, Iis Rizki Widarto, Mulyo Yusuf Kurniawan Zen, Achmad Lutfi