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All Journal Jurnal Veteriner Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Kesehatan Hesti Wira Sakti Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Jurnal Ilmu Kefarmasian Indonesia Pharmaceutical Journal of Indonesia Keluwih: Jurnal Kesehatan dan Kedokteran Sainstech Farma: Jurnal Ilmu Kefarmasian Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Jurnal Bina Pengabdian Kepada Masyarakat Jurnal Inkofar Jurnal Endurance: Kajian Ilmiah Problema Kesehatan Indonesian Journal of Cancer Jurnal Farmasi Sains dan Praktis SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Mestaka: Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Masyarakat Bangsa Herbal Medicine Journal GEMBIRA (Pengabdian Kepada Masyarakat) PEDAMAS (Pengabdian Kepada Masyarakat) Jurnal Kepengawasan, Supervisi dan Manajerial (JKSM) Borneo Journal of Pharmacy Science and Technology: Jurnal Pengabdian Masyarakat JCSE: Journal of Community Service and Empowerment Jurnal Farmasi Ma Chung: Sains, Teknologi, dan Klinis Komunitas Jihapenmas Jurnal Kefarmasian Indonesia Journal of Tropical Pharmacy and Chemistry Masyarakat: Jurnal Pengabdian
Teodhora, Teodhora
Fakultas Farmasi, Institut Sains Dan Teknologi Nasional, Jakarta
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Journal : Jurnal Veteriner

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Antipyretic Activity of The Combination of Momordica charantia L. and Carica papaya L.on Male Mice (Mus musculus) Muhammad Furqan; Herdini Herdini; teodhora teodhora
Jurnal Veteriner Vol 24 No 4 (2023)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19087/jveteriner.2023.24.4.452

Abstract

Fever or pyrexia is a symptom of an illness. Disease infections such as dengue fever, typhus, malaria, liver inflammation, and other infectious diseases are examples of diseases that often cause fever symptoms. To reduce this negative impact means that fever needs to be treated with antipyretics. This study was aimed to determine the antipyretic effectiveness of a combination of papaya and leaf extracts of pare. A total of 15 healthy male mice (Mus musculus) of the ddY strain were 2-3 months old with a weight of 20-30 g were used in this study. Treatment in five groups is group I; ibuprofen 400 mg, group II; Carboxymethyl Cellulosa or CMC-Na 1%, group III (100:100) mg/kg BW, group dose IV (50:150) mg/kg BW, and group dose V (150:50) mg/kg BW, induced fever using the diptheria, pertussis, tetanus (DPT) vaccine with a volume of 0.1 cc (IP) and carried out three repetitions. Observations were made by measuring the rectal temperature of mice using a digital thermometer before DPT vaccine injection or average temperature, 0 minutes (after DPT vaccine injection), 30, 60, 90, and 120 minutes after administering test materials. The combination of papaya leaves and pare leaves can reduce the body temperature of mice. The dose (150:50) mg/kg BW provides the reduction in weight loss body temperature of mice; however, it was not significantly different from ibuprofen.
Co-Authors Agung Endro Nugroho Ainun Wulandai Ainun Wulandari Akhatik, Nurul Amalia Khoirunnisa Andini, Issri Mila Nova Annisa Aulia Rahmawati Arsa, Imalia Aulia Rahimi Awaliya, Azmi Azizah, Shandy Barakatun Nisak Chori Azizah Dea Selia Devi Purwita Sari Dienillah, Qonita Dini Juliana Diny Auliya Mawarni Djuhariah, Yayah Siti Dwi Okta Mellya Eka Putri Maliawati Elmira Yulian Yori Elva Asrida Sipayung Elzius Fransiscus Lumban Gaol Erna Yanti Erwi Putri Setyaningsih Eva Oktavia Fathin Hamida Febriani , Amelia Febriani, Amelia Firdaus Firdaus Fitria Rahayu Fitria Yustisiani Gaol, Elzius Fransiscus Lumban Gunawan Pamudji Widodo Herdini Herdini , Herdini Hervianti Nurfitria Nugrahani Hirim Hotma Uli Aprianis Ika Maruya Kusuma Jaya, Rendy Indra Jessica Khairunnisa Karina Sinungan, Ulfa Mutia Kinanthi Kusumawardhani Krisnawati, Indah Kusuma , Ika Maruya Kusuma, Ika Maruya Lestiana, Elina Lidia Anggita Ramadhani Lili Musnelina Magvierah, Vidya Maigoda, Tonny Cortis Maliawati, Eka Putri Manalu, Rosario Trijuliamos Marsa Falihah Muh. Faris Hidayat Muhammad Furqan Mulandita Munawarohthus Sholikha Munawarohthus Sholikhah Musnelina , Lili Ni’matul Khoeriyah Nopianti, Hermila Nugrahani, Hervianti Nurfitria Nurul Akhatik Nurul Fajri Pontoan, Jenny Pratiwi Ally Florentina Pratiwi, Ritha Widya Pujiastuti, Fitria Putri, Elvina Triana Rachmatiah, Tiah Ratna Nilam Cahya Refdanita Refdanita Refdanita Refdanita Refdanita Refdanita Refdanita Risma Eka Putri Ritha Widyapratiwi Rogahang, Preisilia Rosario Trijuliamos Manalu Rosario Trijuliamos Manalu Saiful Bahri Saiful Bahri Saputra, Richi Andika Setiadi, Fandy Rezha Shella Utami Sholikhah , Munawarohthus Sister Sianturi Siswati Siswati Siti Fadila Azahra Soehartati, Tri Sonia Mutiara Subaryanti Subaryanti, Subaryanti Suci Tiara Syafriana, Vilya Tanama, Celin Gracela Teti Indrawati Teti Indrawati Tiah Rachmatiah Tri Soehartati Veryanti, Putu Rika Vina Novia Welisa, Selfina Junita Widyapratiwi , Ritha Widyapratiwi, Ritha Windiarto, Henriko Suryo Wulandari , Ainun Yayah Siti Djuhariah Yunisa Simehete Zabitha Zahwa Zahra, Aishah Az