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Pengembangan Metode Edukasi dan Pengawasan Kepatuhan Minum Obat Hipertensi di Kecamatan Gunung Sindur Delphia Hermada Marchia; Ima Maria; Primayanti Nurul Ilmi; Eldiza Puji Rahmi
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 6, No 1 (2025): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v6i1.25417

Abstract

Hipertensi di Indonesia sering ditemukan pada pelayanan kesehatan primer. Prevalensi hipertensi di Kabupaten Bogor Tahun 2019, terhadap jumlah penduduk usia ≥ 15 tahun yaitu sebesar 1.313.562 kasus. Terapi hipertensi merupakan terapi yang harus dilakukan seumur hidup, namun berdasarkan Laporan Riskesdas tahun 2018 mendapatkan hasil bahwa kepatuhan dalam minum obat pada pasien hipertensi tergolong rendah. Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian edukasi terhadap tingkat kepatuhan minum obat hipertensi di Puskesmas Gunung Sindur Kabupaten Bogor. Desain penelitian ini adalah kuasi eksperimen dengan satu grup pre-post test. Variabel independen dalam penelitian ini adalah pemberian edukasi terhadap pasien hipertensi dan variabel dependennya adalah kepatuhan minum obat pada pasien hipertensi setelah hari ke-21 pemberian edukasi. Hasil penelitian ini menunjukkan bahwa terdapat pengaruh pemberian edukasi terhadap tingkat kepatuhan minum obat (p < 0,0001) dan penurunan terhadap tekanan darah sistol responden (p < 0,0001) serta diastol (p < 0,003). Pemberian edukasi dapat memengaruhi tingkat kepatuhan minum obat serta tekanan darah pasien hipertensi secara signifikan.
Assessing the Impact of Opioid Analgesics on Pain Intensity Among Breast Cancer Inpatients at Dharmais Cancer Hospital, Jakarta Annisa Farida Muti; Salsabila Azka Maharan Azka Maharani; Dhigna Luthfiyani Citra Pradana Pradana; Eldiza Puji Rahmi
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 15 No 1 (2026): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v15i1.730

Abstract

Pain is a significant primary complaint among breast cancer patients. The WHO Analgesic Ladder guidelines recommend the use of opioid analgesics as a primary management strategy for cancer pain. However, a periodic evaluation of its effectiveness in specific populations remains necessary. This study aimed to evaluate the effectiveness of opioid analgesic therapy in reducing pain intensity for breast cancer inpatients at Dharmais Cancer Hospital, Jakarta, in 2023. This research was an observational study with a retrospective design. The study sample comprised 58 medical records from breast cancer inpatients who had received opioid analgesic therapy, collected using a total sampling technique. Data analysis was performed using the non-parametric Wilcoxon signed-rank test to compare pain intensity before and after the administration of therapy. The results of the statistical analysis demonstrated a highly significant reduction in pain scores following the administration of opioid analgesic therapy (p < 0.001). The administration of opioid analgesics were significantly effective in the management of pain for breast cancer patients at Dharmais Cancer Hospital, Jakarta.
Effectiveness of Anaemia Therapy in Breast Cancer Patients with Chemotherapy-Induced Anaemia at Dharmais Cancer Hospital Jakarta in 2023 Muti, Annisa Farida; Yasya Sabrinanissa; Rahmi, Eldiza Puji; Pradana, Dhigna Luthfiyani Citra
Pharmaceutical Journal of Indonesia Vol. 11 No. 2 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Introduction: Chemotherapy-induced anemia is a common complication in breast cancer patients, primarily caused by bone marrow suppression, which inhibits erythropoiesis and reduces hemoglobin levels. Effective management of anemia is crucial in improving patients' quality of life and tolerance to cancer therapy. This study aims to evaluate the clinical effectiveness of anemia therapy, including packed red cell (PRC) transfusion and erythropoiesis-stimulating agents (ESA) administration, in breast cancer patients post-chemotherapy at Dharmais Cancer Hospital in Jakarta. Methods: The study design used was a retrospective observational study with data collected from inpatient medical records throughout 2023. A total of 35 patient records were selected using total sampling technique. Hemoglobin levels before and after anemia therapy were analyzed using paired statistical tests to assess the effectiveness of the therapy. Results: The analysis results showed a statistically significant increase in hemoglobin levels after therapy was administered (p < 0.001). Conclusion: indicating that both PRC transfusions and ESA therapy effectively contributed to correcting post-chemotherapy anemia in breast cancer patients.
Effectiveness of Anaemia Therapy in Breast Cancer Patients with Chemotherapy-Induced Anaemia at Dharmais Cancer Hospital Jakarta in 2023 Muti, Annisa Farida; Yasya Sabrinanissa; Rahmi, Eldiza Puji; Pradana, Dhigna Luthfiyani Citra
Pharmaceutical Journal of Indonesia Vol. 11 No. 2 (2026)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/

Abstract

Introduction: Chemotherapy-induced anemia is a common complication in breast cancer patients, primarily caused by bone marrow suppression, which inhibits erythropoiesis and reduces hemoglobin levels. Effective management of anemia is crucial in improving patients' quality of life and tolerance to cancer therapy. This study aims to evaluate the clinical effectiveness of anemia therapy, including packed red cell (PRC) transfusion and erythropoiesis-stimulating agents (ESA) administration, in breast cancer patients post-chemotherapy at Dharmais Cancer Hospital in Jakarta. Methods: The study design used was a retrospective observational study with data collected from inpatient medical records throughout 2023. A total of 35 patient records were selected using total sampling technique. Hemoglobin levels before and after anemia therapy were analyzed using paired statistical tests to assess the effectiveness of the therapy. Results: The analysis results showed a statistically significant increase in hemoglobin levels after therapy was administered (p < 0.001). Conclusion: indicating that both PRC transfusions and ESA therapy effectively contributed to correcting post-chemotherapy anemia in breast cancer patients.
COMPARATIVE TEST OF EFFECTIVENESS OF ALCOHOL MIXTURE BASE HAND SANITIZER WITH CHLORHEXIDINE MIXTURE BASE ON ESCHERICHIA COLI AND SHIGELLA SONNEI BACTERIA eldiza puji rahmi; Annisa Farida Muti; Dhinga Luthfiyani Pradana; Mikhael Valentino; Salwa Nisrina Cahyadi; Putri Andini; Muhamad Ferdian; Tiyon Widjaja; Brooklyn Razan Fachrudin; Annisa Hasna Nabila; Salsabilla Puteri Wandira; Sirly Marliah Saputri; Khayla Shifa Azzahra; Alfina Aprilia Kusumaningrum; Cut Laila Nur Shabrina; Rabbiah Putri Nurjannah
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 2 No 1 (2023): Vol.2 No.1 JUNE (2023)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v2i1.7013

Abstract

ABSTRACT Hand sanitizer is a hand cleanser which is easy and practical in use. Using hand sanitizer can be an alternative for washing hands if in condition without water and soap. Hand sanitizer is used to clean pathogens on hands. The ability to kill pathogens in hand sanitizers is due to the active substance content in them. In this research, the effectiveness of 2 hand sanitizers on the market was tested. The test aims to see the effect of the active substances in each preparation on the effectiveness of killing pathogens. Testing was carried out using the Kirby Bauer method and on 2 bacterial media, namely Escherichia coli and Shigella sonnei. Hand sanitizer 1 has a composition consisting of 70% ethyl alcohol and 0.5% chlorhexidine. Hand sanitizer 2 has a composition consisting of 55% ethyl alcohol and 18% isopropyl alcohol with a total of 73% alcohol. Based on observations, it was found that hand sanitizer 1 was more effective than hand sanitizer 2. The chlorhexidine content in hand sanitizer 1 increased its effectiveness in killing pathogens.
COMPARING ANTIMICROBIAL EFFICACY OF DIFFERENT HAND SANITIZERS IN PSEUDOMONAS AERUGINOSA AND STAPHYLOCOCCUS AUREUS Zeashafa Zafira Ramdhan; Roqayyah; Salma Ika Rahmadani; Nasyia Qaanita; Anggita Virginia Naulina Manurung; Tirta Fitri Aryani; Nafis Ikhwana; Anggita Cahya Ningrum; Nasywa Dwi Ayu; Afdhal Raziq Hanania; Deskia Amanda Fitriyani; Kharazi Farand Vitonova; Dhigna Luthfiyani Citra Pradana; Eldiza Puji Rahmi; Annisa Farida Muti
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 3 No 1 (2024): Vol.3 No.1 JUNE (2024)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v2i2.7017

Abstract

Human activities every day have a lot of physical contact with the environment, this can cause various kinds of diseases. These diseases can come from various types of microorganisms such as bacteria, fungi and viruses. Examples of bacteria that can cause disease are Escherichia coli and Staphylococcus aureus. Escherichia coli and Staphylococcus aureus are Gram-positive and Gram-negative bacteria that most commonly cause diarrhoea. To avoid these bacteria, humans need to wash their hands using soap and clean running water. However, washing hands cannot be done every time and in every place. Therefore, there is an innovation of hand sanitizer without using running water, namely hand sanitizer. Hand sanitizer is a waterless hand sanitizer innovation that contains antiseptic substances. Hand sanitizer works as an antibacterial in inhibiting and even killing bacteria. Antiseptics are chemical compounds used to inhibit or kill microorganisms in living tissue. The purpose of using antiseptics is to inhibit or kill bacteria by inhibiting bacterial enzymes and reducing the permeability of bacterial cell membranes through bacterial precipitation, oxidation, and halogenation. Antiseptics usually contain alcohol, chlorhexidine, and anilides. Antiseptics that are widely used in the medical world are antiseptics with alcohol content based on the ability of alcohol to kill bacteria.
ASSESSMENT OF KNOWLEDGE AND SELF-MEDICATION PRACTICE OF DYSMENORRHEA AMONG PHARMACY UNDERGRADUATE STUDENTS: A CROSS-SECTIONAL STUDY Eldiza Puji Rahmi, M.Sc; Bella Ananda; Imam Prabowo; Dhigna Luthfiyani Citra Pradana
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 2 No 2 (2023): Vol.2 No.2 DECEMBER (2023)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v2i2.7207

Abstract

Dysmenorrhea is pain during menstruation that is experienced during adolescence caused by uterine muscle spasms. Data on knowledge of dysmenorrhea and self-medication practice among undergraduate student at Universitas Pembangunan Nasional Veteran Jakarta (UPN Veteran Jakarta) are scarce. This study aimed to assess and determine the relationship between the level of knowledge and primary dysmenorrhea self-medication practice. A cross-sectional study was carried out among female undergraduate Pharmacy Student of UPN Veteran Jakarta. A total of 107 unmarried and nulliparous female students were included in this study using the stratified random sampling technique. Based on the results of the study, 47 students (43.9%) had adequate knowledge, 46 students (43.0%) had moderate knowledge, and 14 students (13.1%) had inadequate knowledge. Forty female students (37.4%) had good practice, 40 female students (37.4%) had moderate practice, and 27 female students (25.2%) had poor practice regarding dysmenorrhea, and in this study, the value of confidentiality (p< 0.05). It is considered significant, with the intention that there is a relationship between the level of knowledge and primary dysmenorrhea self-medication.
THE RELATIONSHIP OF COMPLIANCE WITH MEDICATION ON BLOOD PRESSURE STABILITY IN HYPERTENSION PATIENTS AT CINERE DISTRICT HEALTH CENTER 2023 Salsabila Sumantri; eldiza puji rahmi; Via Rifkia; Dhinga Luthfiyani Pradana
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 2 No 2 (2023): Vol.2 No.2 DECEMBER (2023)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v2i2.7416

Abstract

Several reasons for hypertension sufferers who do not comply with taking medication will slow down healing time and worsen the patient's condition and can even cause death. This study aims to determine the characteristics of hypertensive patients at the Cinere Community Health Center, the results of antihypertensive therapy at the Cinere Community Health Center and to determine the relationship between adherence to medication use and the success of therapy at the Cinere Community Health Center. This research uses a correlational analytical research design. Based on the discussion above, it can be concluded that the characteristics of hypertensive patients at the Cinere Community Health Center are the majority aged 45-65 years, female with the highest education level being elementary school and having suffered for > 1 year. The majority of medication adherence among hypertensive patients at the Cinere Community Health Center is still relatively low. The success of therapy in hypertensive patients at the Cinere Community Health Center resulted in a reduction in blood pressure of 31 people and in patients who did not reduce blood pressure there were 71 people. There is a relationship between adherence to taking medication and blood pressure stability in hypertensive patients at the Cinere Community Health Center
Association between Hormonal Contraceptive Use and Hypertension Risk among Reproductive-Age Women: A Cross-sectional Study at Cileungsi Public Health Center, Indonesia Defa Nafara Maharani Itamy; Eldiza Puji Rahmi; Dhigna Luthfiyani Citra Pradana; Annisa Farida Muti
Media Farmasi: Jurnal Ilmu Farmasi Vol. 22 No. 2 (2025): September 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v22i2.31400

Abstract

Hypertension remains a major public health problem that may be influenced by hormonal contraceptive use, particularly oral and injectable methods commonly used by women of reproductive age. These contraceptives have raised concerns about their potential impact on blood pressure regulation. This study aimed to investigate the association between hormonal contraceptive use and the occurrence of hypertension among women of reproductive age at the Cileungsi Public Health Centre, Bogor Regency, Indonesia. A cross-sectional study was conducted in 2024 using retrospectively collected medical record data of all hormonal contraceptive users at the facility. Total sampling was applied, and data on contraceptive type, duration of use, age, parity, and the most recent blood pressure readings were analyzed. The chi-square test was employed to examine associations between hormonal contraceptive characteristics and hypertension, with a significance level set at p < 0.05. The results revealed a significant association between contraceptive type and hypertension (p = 0.01, OR = 0.27), showing that users of oral contraceptive pills were more likely to develop hypertension than injectable users. Duration of use (p = 0.03, OR = 3.06), age (p = 0.04, OR = 0.12), and parity (p = 0.01, OR = 0.21) were also significantly associated with hypertension. Women aged ≥45 years, those with longer contraceptive use, and multiparous users exhibited a higher risk of elevated blood pressure. These findings highlight that both contraceptive-related and demographic factors contribute to hypertension risk among hormonal contraceptive users. Regular blood pressure monitoring and individualized counseling are essential, especially for oral and long-term users. This study contributes local evidence supporting safer contraceptive practices and cardiovascular risk management within primary healthcare settings.
Optimization of Ultrasonic-Assisted Extraction Parameters and Antibacterial Activity of Zanthoxylum acanthopodium D.C against Cutibacterium acnes Eldiza Puji Rahmi; Rini Sarah Pasaribu; Erna Harfiani; Rika Revina; Abdi Wira Septama
Pharmacon: Jurnal Farmasi Indonesia Vol. 22 No. 2 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i2.5932

Abstract

Acne is a disease that has affected many populations globally. One of the causes of acne is the presence of acne-causing bacteria, namely Cutibacterium acnes, which is reportedly resistant to several antibiotics. Andaliman fruit (Zanthoxylum acanthopodium DC.) is traditionally used by Indonesian people as a spice which has antibacterial potential. This study aims to evaluate the antibacterial activity of the ethanolic extract of Andaliman fruit against C. acnes using the microdilution method. The extraction method for andaliman fruit was the Ultrasonic-Assisted Extraction with variations in frequency (30, 40, and 50 kHz) and duration (10, 15, and 20 minutes). Phytochemical screening showed the presence of flavonoids, alkaloids, tannins, steroids, and saponins in the extract. The results showed the antibacterial activity of Andaliman fruit extract against C. acnes, with the Minimum Inhibitory Concentration (MIC) observed in the extract with a frequency of 40 kHz and an extraction duration of 10 and 15 minutes at a concentration of 5000 ppm. However, the Minimum Bactericidal Concentration (MBC) test showed negative results, indicating that Andaliman extract did not have a bactericidal effect on these bacteria. Statistical analysis using the Kruskal–Wallis and Dunn tests revealed significant differences (p < 0.05) between extraction treatments and the positive control in MIC and MBC values. These findings indicate that the ethanolic extract of andaliman fruit possesses inhibitory but not bactericidal activity against C. acnes, suggesting its potential as a natural anti-acne agent for further formulation and mechanistic studies.