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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Medika Kartika : Jurnal Kedokteran dan Kesehatan Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Bakti Masyarakat Indonesia Jurnal Pengabdian Masyarakat (ABDIRA) Journal of Research in Pharmacy and Pharmaceutical Sciences Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia Clinical and Pharmaceutical Sciences Journal Jurnal Serina Abdimas
Rahmi, Eldiza Puji
Fakultas Kedokteran UPN Veteran Jakarta
Aerospace Engineering Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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EDUKASI PEMANFAATAN LIMBAH ORGANIK SEBAGAI ECO-ENZYME UNTUK PRODUK KESEHATAN BAGI MASYARAKAT RAWA KOPI-DEPOK Rahmi, Eldiza Puji; Revina, Rika; Farkhani, Aulia
Jurnal Bakti Masyarakat Indonesia Vol. 6 No. 3 (2023): Jurnal Bakti Masyarakat Indonesia
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/jbmi.v6i3.26792

Abstract

Waste from the production process in the community around Rawa Kopi, Depok, is one of the problems in their environment that requires further processing. Eco-enzyme is a potential organic waste processing technology and can be an effort to achieve the 12th SDGs goal regarding sustainable production and consumption patterns. This technology involves a fermentation process of organic waste combined with brown sugar/molasses and air in a certain ratio. The eco-enzyme liquid produced is an active ingredient that can be used for various purposes. This community service activity aims to provide outreach and education in utilizing waste, especially organic waste, which can be processed into eco-enzymes for the community around Rawa Kopi, Depok. The activity began with giving a pretest, then socialization about eco-enzymes through lectures and interactive discussions. Evaluation is carried out on the process, including attendance, enthusiasm/enthusiasm, participants' responses to training activities, and post-test material education. The results of the activity will provide knowledge to utilize organic waste around us into eco enzymes, which can then be further utilized into materials such as fertilizer, disinfectant, hand sanitizer and others. Community knowledge and understanding in utilizing organic waste around us into eco enzymes can increase after the activity. The results of the activity were able to provide knowledge about degenerative diseases and the use of Indonesian medicinal plants for degenerative diseases. Community knowledge and understanding of degenerative diseases and recognizing and utilizing plant medicines can increase significantly (p<0.001) after the activity up to 77.57%. ABSTRAK; ABSTRAK Limbah dari proses produksi pada UMKM masyarakat sekitar Rawa Kopi, Depok, menjadi salah satu permasalahandi lingkungan mereka yang memerlukan pengolahan lebih lanjut. Eco-enzyme adalah salah satu teknologipengolahan sampah organik yang potensial dan dapat menjadi salah satu upaya mencapai tujuan SDGs ke-12terkait pola produksi dan konsumsi yang berkelanjutan. Teknologi ini melibatkan proses fermentasi sampah organikyang dikombinasikan dengan gula merah/molase dan air dengan perbandingan tertentu. Cairan eco-enzim yangdihasilkan merupakan bahan aktif yang dapat digunakan untuk berbagai kepentingan. Kegiatan pengabdian kepadamasyarakat ini bertujuan untuk memberikan sosialisasi dan edukasi dalam memanfaatkan limbah terutama limbahorganik yang dapat diolah menjadi eco-enzyme bagi masyarakat sekitar Rawa Kopi, Depok. Kegiatan dimulaidengan pemberian pretest, selanjutnya sosialisasi mengenai eco-enzyme melalui ceramah dan diskusi interaktif.Evaluasi dilakukan terhadap proses yang meliputi kehadiran, semangat/antusiasme, dan respon/tanggapan pesertaterhadap kegiatan pelatihan, serta posttest materi edukasi. Hasil kegiatan diharapkan mampu memberikanpengetahuan untuk memanfaatkan sampah organik di sekitar kita menjadi eco enzyme yang selanjutnya dapatdimanfaatkan lebih jauh menjadi bahan-bahan seperti pupuk, desinfektan, hand sanitizer dan lain-lain.Pengetahuan dan pemahaman masyarakat dalam memanfaatkan sampah organik di sekitar kita menjadi eco enzymebisa meningkat setelah kegiatan. Hasil kegiatan mampu memberikan pengetahuan tentang pemanfaatan limbahorganik sebagai eco-enzyme untuk produk kesehatan. Pengetahuan dan pemahaman masyarakat meningkat secarasignifikan (p<0,001) setelah kegiatan hingga 77,57%.
Association between Hormonal Contraceptive Use and Hypertension Risk among Reproductive-Age Women: A Cross-sectional Study at Cileungsi Public Health Center, Indonesia Nafara Maharani Itamy, Defa; Rahmi, Eldiza Puji; Luthfiyani Citra Pradana, Dhigna; Farida Muti, Annisa
Media Farmasi: Jurnal Ilmu Farmasi Vol. 22 No. 2 (2025): September 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v22i2.31400

Abstract

Hypertension remains a major public health problem that may be influenced by hormonal contraceptive use, particularly oral and injectable methods commonly used by women of reproductive age. These contraceptives have raised concerns about their potential impact on blood pressure regulation. This study aimed to investigate the association between hormonal contraceptive use and the occurrence of hypertension among women of reproductive age at the Cileungsi Public Health Centre, Bogor Regency, Indonesia. A cross-sectional study was conducted in 2024 using retrospectively collected medical record data of all hormonal contraceptive users at the facility. Total sampling was applied, and data on contraceptive type, duration of use, age, parity, and the most recent blood pressure readings were analyzed. The chi-square test was employed to examine associations between hormonal contraceptive characteristics and hypertension, with a significance level set at p < 0.05. The results revealed a significant association between contraceptive type and hypertension (p = 0.01, OR = 0.27), showing that users of oral contraceptive pills were more likely to develop hypertension than injectable users. Duration of use (p = 0.03, OR = 3.06), age (p = 0.04, OR = 0.12), and parity (p = 0.01, OR = 0.21) were also significantly associated with hypertension. Women aged ≥45 years, those with longer contraceptive use, and multiparous users exhibited a higher risk of elevated blood pressure. These findings highlight that both contraceptive-related and demographic factors contribute to hypertension risk among hormonal contraceptive users. Regular blood pressure monitoring and individualized counseling are essential, especially for oral and long-term users. This study contributes local evidence supporting safer contraceptive practices and cardiovascular risk management within primary healthcare settings.
PENDAMPINGAN KADER KESEHATAN KECAMATAN CINERE DEPOK DALAM UPAYA MENCEGAH STUNTING DENGAN METODE CARA BELAJAR INSAN AKTIF Pradana, Dhigna Luthfiyani Citra; Sartika, Luthfiah Dewi; Rahmi, Eldiza Puji; Muti, Annisa Farida; Syarifah, Andiri Niza; Ilmi, Primayanti Nurul
Jurnal Serina Abdimas Vol 1 No 4 (2023): Jurnal Serina Abdimas
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/jsa.v1i4.28336

Abstract

Malnutrition in children who are stunted occurs from the baby in the womb to after birth or commonly called the First 1,000 Days of Life (HPK). Stunting prevention is more effective than stunting treatment. Therefore, the purpose of this community service is to assist health cadres of Cinere sub-district in preventing stunting. The method used in this community service is education on how to learn active people and participants are given pre-test and post-test. The activeness of community service participants is expected to make it easier to understand stunting prevention education by seeing and discussing vitamins and minerals needed in stunting prevention. The results of community service were followed by 113 people divided into 4 villages in Cinere District, Depok City. Most of the participants were mothers so that information and implementation of stunting prevention could be seen immediately. There was a significant difference of 0.000 between pretest and posttest values analyzed using the Wilcoxon test on SPSS. The results of the pre-test and post-test assessments, attitudes and understanding of health cadres in Cinere sub-district increased by an average of around 87, so it can be assumed that the participants had understood the educational material for stunting prevention in Cinere sub-district, Depok city. Kekurangan gizi pada anak yang mengalami stunting terjadi sejak bayi dalam kandungan hingga setelah lahir atau biasa disebut 1.000 Hari Pertama Kehidupan (HPK). Pencegahan stunting lebih efektif dibandingkan pengobatan stunting. Oleh karena itu tujuan dari pengabdian masyarakat ini adalah untuk mendampingi kader Kesehatan kecamatan cinere dalam mencegah kejadian stunting. Metode yang digunakan dalam pengabdian masyarakat ini yaitu edukasi cara belajar insan aktif serta para peserta diberikan pre-test dan post-test. Keaktifan para peserta pengabdian masyarakat diharapkan dapat memudahkan untuk memahami edukasi pencegahan stunting dengan melihat serta mendiskusikan vitamin dan mineral yang dibutuhkan dalam pencegahan stunting. Hasil pengabdian masyarakat diikuti 113 orang yang terbagi menjadi 4 kelurahan di Kecamatan Cinere Kota Depok. Sebagian besar peserta adalah seorang ibu sehingga informasi dan penerapan pencegahan stunting langsung dapat dilihat hasilnya. Terdapat perbedaan yang signifikan 0,000 antara nilai pretest dan posttest yang dianalisis menggunakan uji Wilcoxon pada SPSS. Hasil penilaian pre-test dan post-test sikap dan pemahaman kader kesehatan di Kecamatan Cinere meningkat rata-rata sekitar 88 sehingga dapat diasumsikan bahwa para peserta telah paham materi edukasi pencegahan stunting di kecamatan cinere kota depok.
Optimization of Ultrasonic-Assisted Extraction Parameters and Antibacterial Activity of Zanthoxylum acanthopodium D.C against Cutibacterium acnes Rahmi, Eldiza Puji; Pasaribu, Rini Sarah; Harfiani, Erna; Revina, Rika; Septama, Abdi Wira
Pharmacon: Jurnal Farmasi Indonesia Vol. 22 No. 2 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i2.5932

Abstract

Acne is a disease that has affected many populations globally. One of the causes of acne is the presence of acne-causing bacteria, namely Cutibacterium acnes, which is reportedly resistant to several antibiotics. Andaliman fruit (Zanthoxylum acanthopodium DC.) is traditionally used by Indonesian people as a spice which has antibacterial potential. This study aims to evaluate the antibacterial activity of the ethanolic extract of Andaliman fruit against C. acnes using the microdilution method. The extraction method for andaliman fruit was the Ultrasonic-Assisted Extraction with variations in frequency (30, 40, and 50 kHz) and duration (10, 15, and 20 minutes). Phytochemical screening showed the presence of flavonoids, alkaloids, tannins, steroids, and saponins in the extract. The results showed the antibacterial activity of Andaliman fruit extract against C. acnes, with the Minimum Inhibitory Concentration (MIC) observed in the extract with a frequency of 40 kHz and an extraction duration of 10 and 15 minutes at a concentration of 5000 ppm. However, the Minimum Bactericidal Concentration (MBC) test showed negative results, indicating that Andaliman extract did not have a bactericidal effect on these bacteria. Statistical analysis using the Kruskal–Wallis and Dunn tests revealed significant differences (p < 0.05) between extraction treatments and the positive control in MIC and MBC values. These findings indicate that the ethanolic extract of andaliman fruit possesses inhibitory but not bactericidal activity against C. acnes, suggesting its potential as a natural anti-acne agent for further formulation and mechanistic studies.
RATIONALITY OF ANTIBIOTIC PRESCRIPTIONS AMONG OUTPATIENTS IN THE INTERNAL MEDICINE CLINIC AT PERSAHABATAN GENERAL HOSPITAL JULY–SEPTEMBER 2023 Artanti, Astrid Nada; Maria, Ima; Rahmi, Eldiza Puji; Citra Pradana, Dhigna Luthfiyani; Diliana, Diliana
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 8 No 4 (2025): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Antibiotic use has increased in both developing countries, such as Indonesia, and developed countries, such as Japan and Australia. This trend may lead to a rise in antibiotic resistance if antibiotics are used irrationally. This study aimed to evaluate antibiotic prescribing patterns using the Gyssens method among adult outpatients in the Internal Medicine Clinic at Persahabatan General Hospital during the period of July–September 2023. This was a descriptive study with a cross-sectional design. Data were collected retrospectively from the medical records of adult outpatients attending the Internal Medicine Clinic during the study period. Of the 30 patient records that met the inclusion and exclusion criteria, the age group 51–60 years represented the largest proportion of antibiotic prescriptions (46.67%). Levofloxacin was the most frequently prescribed antibiotic (30.3%). Based on the Gyssens method, 88.8% of prescriptions were classified as rational, while 11.1% were irrational. In conclusion, 88.8% of antibiotics prescribed for adult outpatients in the Internal Medicine Clinic at Persahabatan General Hospital during July–September 2023 were deemed rational according to the Gyssens method. Keywords : antibiotics, gyssens method, outpatient DOI : 10.35990/mk.v8n4.p400-411
Pharmacokinetic Evaluation of Paracetamol Co-administered with Moringa oleifera and Caesalpinia sappan Extracts Individually in Sprague Dawley Rats Pradana, Dhigna; Nur, Syifa; Hakim, Annisa Ayu Nur; Rahmi, Eldiza Puji; Muti, Annisa Farida; Abdurrahman Munir, Muhammad
Clinical and Pharmaceutical Sciences Journal Vol. 2 No. 1 (2026)
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/clips.v2i1.579

Abstract

Paracetamol is frequently utilized to alleviate pain and fever due to its pharmacological properties as an analgesic and antipyretic. Consuming paracetamol drugs while self-medication might potentially lead to drug interactions when used with other medications, as well as certain foods and herbs. Moringa oleifera and Caesalpinia sappan are popular herbal plants in Indonesia, commonly used to produce herbal food and drinks. These plants contain flavonoids and phenols, which have the potential to impact the metabolism, effectiveness, and toxicity of medications, including paracetamol. This study investigated alterations in the pharmacokinetic characteristics of paracetamol when co-administered with Moringa oleifera and Caesalpinia sappan. The research utilized a true experimental approach with a posttest-only control group design and animal model study is male Sprague-Dawley rats . The control group was administered an oral dose of 9mg/200g body weight of paracetamol. By contrast, the treatment group of male Sprague-Dawley rats was administered an oral dose of 9mg/200g body weight of paracetamol, combined with a dose of 60mg/200g of Moringa leaf extract and sappan heartwood extract at 294 mg/kg body weight. At 30, 60, 120, 180, and 240 minutes, blood samples were collected from the rats' lateral tail vein. Analyzing the concentration of paracetamol in plasma was conducted using a UV-Vis spectrophotometer set at a wavelength of 244 nm. The study showed that combining sappan heartwood extract with paracetamol resulted in a substantial 453.10% increase in the volume of distribution (Vd) (p<0.05). The administration of Moringa leaf extract decreased a little effect the pharmacokinetic profile of paracetamol, as shown by the statistical analysis of the unpaired t-test (p>0.05).
Co-Authors Abdi Wira Septama Abdi Wira Septama Abdurrahman Munir, Muhammad Afdhal Raziq Hanania Ananda, Bella Anggita Cahya Ningrum Anggita Virginia Naulina Manurung Annisa Farida Muti Artanti, Astrid Nada Azzahra, Khayla Shifa Cahyadi, Salwa Nisrina Deskia Amanda Fitriyani Dhigna Luthfiyani Citra Pradana Dian Mega Sugiyarto Diliana, Diliana Erna Harfiani Farida Muti, Annisa Farkhani, Aulia Ferdian, Muhamad Hakim, Annisa Ayu Nur Ima Maria Imam Prabowo, Imam Kharazi Farand Vitonova Kusumaningrum, Alfina Aprilia Luthfiyani Citra Pradana, Dhigna Marchia, Delphia Hermada Maria, Ima Marliah Saputri, Sirly Nabila, Annisa Hasna Nafara Maharani Itamy, Defa Nafis Ikhwana Nasyia Qaanita Nasywa Dwi Ayu Nur, Syifa Nurjannah, Rabbiah Putri Pasaribu, Rini Sarah Pradana, Dhigna Pradana, Dhinga Luthfiyani Primayanti Nurul Ilmi Putri Andini, Putri Ramdhan, Zeashafa Zafira Razan Fachrudin, Brooklyn Revina, Rika Rifkia, Via Roqayyah Salma Ika Rahmadani Sartika, Luthfiah Dewi Shabrina, Cut Laila Nur Situmorang, Vania Clarissha Sumantri, Salsabila Syarifah, Andiri Niza Tirta Fitri Aryani Valentino, Mikhael Wandira, Salsabilla Puteri Widjaja, Tiyon