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Journal : CHEMPUBLISH JOURNAL

Formulasi Nanopartikel Ekstrak Buah Naga (Hylocereus Polyrhizus) Sebagai Zat Warna Sediaan Lipstik Indri Maharini
CHEMPUBLISH JOURNAL Vol. 2 No. 1 (2017): Chempublish Journal
Publisher : Universitas Jambi, Fakultas Sains dan Teknologi, Program Studi Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (364.582 KB)

Abstract

Lipstick merupakan sediaan dekoratif yang banyak digunakan oleh wanita. Dalam sediaan ini biasanya mengandung bahan pewarna sintetik. Penggunaan lipstick sangat mungkin tertelan bersama ludah, makanan dan minuman oleh karena itu sangat berbahaya jika dalam sediaan lipstik mengandung zat pewarna berbahaya. Zat warna alami dibutuhkan keberadaannya karena dianggap lebih aman dibandingkan dengan pewarna sintetik. Buah naga merupakan tanaman yang mengandung betasianin. Senyawa ini merupakan zat warna merah pada buah yang berkhasiat sebagai antioksidan. Antioksidan diperlukan dalam formulasi sediaan lipstick untuk mencegah teroksidasinya lemak dari basis yang dapat menyebabkan bau tengik pada sediaan. Dalam penelitian ini akan dilakukan formulasi nanopartikel ekstrak buah naga. Nanopartikel mampu mencegah terjadinya migrasi zat warna pada sediaan lipstick. Metode pembuatan sediaan nanopartikel menggunakan gelasi ionic. Komposisi formula nanopartikel buah naga yaitu : eksrak cair buah naga konsentrasi 1 g/ 25 ml 4 bagian, larutan kitosan 1 mg/ml 1 bagian dan 0,05 bagian Na TPP konsentrasi 0,4 mg/ml. hasil sediaan nanopartikel menunjukkan larutan opalesen dan stabil dalam penyimpanan. Sediaan lipstick berkonsisitensi rendah dengan warna pink pucat. Kata kunci: nanopartikel, buah naga, antioksidan, zat warna, lipstik
Nanoparticles Formulated from Young Areca Nut Extract Utilizing Sodium Alginate as a Polymer and Calcium Chloride (CaCl2) Rohmahdana, Indis Hilwa; Maharini, Indri; Purba, Eka Novita Br; Salsabilah, Indah; Nugroho, Aulia Hafizhah; Virginia, Yulwilla
Chempublish Journal Vol. 8 No. 2 (2024): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v8i2.38128

Abstract

Nanoparticles are an innovative formulation designed to enhance the bioavailability of drugs with poor absorption while allowing for a more targeted release of active compounds to minimize the risk of side effects. This study aims to develop nanoparticle formulations of young areca nut extract. The ionic gelation method, utilizing 0.02% CaCl2 and 0.1% sodium alginate, was employed in the preparation process. The three formulas were developed with different concentrations and volumes of extract. The evaluation of nanoparticles included phytochemical screening, particle size analysis (PSA), zeta potential, % transmittance, and FTIR for functional group identification. The characterization results of the nanoparticles from young areca nut seed ethanol extract showed that formulas F1, F2, and F3 had particle sizes of 84.267±1.250 nm, 97.367±1.079 nm, and 82.333±0.723 nm, respectively. The polydispersity index values ranged from 0.254±0.046 to 0.325±0.02, suggesting good particle distribution. The zeta potential values, all below -30 mV, indicate the stability of the colloidal suspension system. FTIR analysis showed that the young areca nut seed extract nanoparticles in all formulas contained functional groups such as alcohol, alkene, and amide.
The Formulation of a Body Scrub Combining Sweet Orange Peel (Citrus x sinensis L.) and Coconut Dregs (Cocos nucifera L.) as an Antioxidant Riziek, Habieb; Arrahman, Ghery; Savitri, Anita; Zahara; Hanifah, Risa; Maharini, Indri; Efendi, M. Rifqi
Chempublish Journal Vol. 8 No. 2 (2024): Chempublish Journal
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v8i2.38181

Abstract

The sweet orange peel (Citrus x sinensis L.) possesses antioxidant properties that can be harnessed for developing a pharmaceutical preparation based on natural ingredients, particularly in skin care products such as body scrubs. Meanwhile, coconut pulp (Cocos nucifera L.) has a textural quality that lends itself to use as a scrubbing agent, capable of removing dead skin cells. This study aimed to ascertain the antioxidant activity of body scrub formulations with varying concentrations of extract. The results of the phytochemical screening indicated the presence of alkaloids, flavonoids, tannins, and triterpenoids. Three formulations of body scrub were prepared, designated FI (1.25% extract), FII (2.5% extract), and FIII (5% extract). The results of the physical tests demonstrated that the organoleptic, pH, spreadability, and adhesion tests met the requisite standards. In the antioxidant activity test with the DPPH reagent, the IC50 value of each formula is as follows: The results demonstrated that the IC50 value of each formula was 7.28 ppm (very strong) for FI, 11.839 ppm (very strong) for FII, and 17.354 ppm (very strong) for FIII.