Article Per Year (5 Year)
p-Index From 2021 - 2026
2.808
P-Index
This Author published in this journals
All Journal MPI (Media Pharmaceutica Indonesiana) Acta Pharmaceutica Indonesia Indonesian Journal of Halal Research Jurnal Humaniora Teknologi Jurnal Humaniora Teknologi Borneo Journal Of Pharmascientech Jurnal Computer Science and Information Technology (CoSciTech) Abdimas: Papua Journal Of Community Service JEMSI (Jurnal Ekonomi, Manajemen, dan Akuntansi) Jurnal Pengabdian Masyarakat Majalah Cendekia Mengabdi Jurnal Jurnal Al-Muharrik: Jurnal Pendidikan Agama Islam Ecoducation Jurnal Serambi Ilmu Indonesian Journal of Islamic Jurisprudence, Economic and Legal Theory
Norhayati
Unknown Affiliation
Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

Published : 17 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Borneo Journal Of Pharmascientech

 1 
Rendemen dan Skrining Fitokimia Simplisia Daun Bayam (Amaranthus viridis) Norhayati; Rizaldi, Gusti; Noorwina, Syifa; Anida
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 1 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i1.522

Abstract

Indonesia is rich in biodiversity. One of the plants that grows widely in Indonesia is spinach (Amaranthus viridis). The aim of this research was to determine the secondary metabolite content of the ethanol extract of spinach leaves (A. viridis) qualitatively. This research consisted of 2 stages. The first stage is making simplicia and the second stage is screening phytochemical simplicia. The yield obtained from making simplicia was 20.83%. Based on the results, it can be concluded that spinach leaves (A. viridis) contain secondary metabolites of alkaloids, tannins, phenols, and saponins. The suggestion for this research is that the secondary metabolites can be isolated and then continued with activity tests.
Studi in silico tentang naringin sebagai reseptor anti-HER-2 dalam pengobatan kanker payudara Abdurrahman, Abdurrahman; Rijal, Muh. Agus Syamsur; Yusuf, Helmy; Norhayati; Rizaldi, Gusti
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 2 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i2.535

Abstract

Overexpression of Human Epidermal Receptor-2 (HER-2) is the cause of the development of breast cancer, so HER-2 can be a target for anticancer therapy. Trastuzumab is the drug of choice in inhibiting the HER-2 receptor and tyrosine kinase, but the weakness of this drug is that drug resistance can occur. Naringin has potential as a breast cancer therapy. The research aims to determine the inhibiting overexpression of the HER-2 receptor by naringin using in silico method. Molecular docking has been carried out by optimizing naringin and trastuzumab, preparing the HER-2 protein target (PDB ID 3PP0), validating the molecular docking protocol, and docking naringin and trastuzumab on HER-2. The research produced a binding energy of -8,66 kcal/mol, while the binding energies of the original ligand and trastuzumab to HER-2 were -9,94 kcal/mol and -5,87 kcal/mol, respectively. The binding energy shows that naringin has potential as an anti-breast cancer agent as indicated by its stronger affinity for HER2.
Co-Authors Abdurahman Abdurrahman Agung Prabowo Agustina, Fitria Sanova Ahmad Syauqi Fuady ANIDA Ariza, A. Firsa Bayu Pratama Nugroho Catharina Elmayantie Catharina Elmayantie, Catharina Chandra, M. Andi Diki Hidayat Elvine Ivana Kabuhung Haris, Ferdiyani Ichsan, Mochammad Ika Safitri Windiarti Irawan, Angga Januar, Khomsya Ninteen Jayanti, Elfa Kholis Amalia Nofianti Luqmanul Hakim Muhammad Agus Syamsur Rijal Noorwina, Syifa Nuntufa Nur Mashani Mustafidah Nurul Amalia Paramita, Diajeng Putri Putra, Christia Rahmah, Helena Rizaldi, Gusti Rosmiati Rusida, Esty Restiana Safitri, Nia Sam'ani Sam'ani Santoso Pakpahan, Herman Sherly Jayanti Sitanggang, Fransiska Sulistyowati Sulistyowati Suparno Toyyibah, Wardah Ula, Ummi Mauliatul Warni Yusuf, Helmy