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All Journal International Journal of Public Health Science (IJPHS) Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Indonesian Journal of Forestry Research Jurnal Penelitian Hutan dan Konservasi Alam Jurnal Penelitian Hasil Hutan Folia Medica Indonesiana Indonesian Journal of Tropical and Infectious Disease Jurnal Penelitian Ekosistem Dipterokarpa Dental Journal (Majalah Kedokteran Gigi) The Indonesian Biomedical Journal Jurnal Ilmiah Rekayasa Pertanian dan Biosistem Health Notions Buletin Farmatera Jurnal Respirasi (JR) Biomolecular and Health Science Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Edukasi: Journal of Educational Research AKSONA Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)

Abdurachman Abdurachman

Department Of Anatomy And Histology, Faculty Of Medicine, Universitas Airlangga, Surabaya

Author-ID : 218132

Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Acupuncture analgesia: The complementary pain management in dentistry Abdurachman Abdurachman
Dental Journal (Majalah Kedokteran Gigi) Vol. 44 No. 1 (2011): March 2011
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Background: Pain is the most common reason for medical consultation in the United States. Pain is a major symptom in many medical conditions, and can significantly interfere with a person’s quality of life and general functioning. One of the very unpleasant pain is toothache. Conventional treatments for toothache are improving oral hygiene, prescribing analgesics, anti-inflammatory, and also antibiotics if there are infection even extractions are performed if necessary. Another way to conventional approaches, patients may consider acupuncture method. Acupuncture involves the insertion of needles with the width of a human hair along the precise points throughout the body. This process triggers body’s energy normal flow through extra anatomy pathway called meridian. Purpose: This case report is aimed to emphasize the existence of teeth-organ relationships through communication channels outside the lines of communication that has been known in anatomy. Case: Two patients with toothache complaints in the lower right molars came to an acupuncturist who was a medical practitioner. In these cases pain were relieved by acupuncture analgesia. Case management: Two patients were subjected to acupuncture analgesia with different acupuncture points that were customized to the affected tooth, case 1 with the large intestine-4 (Li-4) which located in the hand and case 2 with bladder-25 (Bl-25) which located in the back of the body. Ninety percent of pain was relieved in 40 seconds. Conclusion: Pain in toothache can be relieved using acupuncture analgesia technique, using meridian as an extra anatomy pathway. Nevertheless, treating the source of pain by dental practitioner is mandatory.Latar belakang: Nyeri adalah alasan paling umum yang menyebabkan orang datang berkonsultasi kepada profesional medis di Amerika Serikat. Nyeri merupakan gejala utama dalam kasus medis, dan dapat mengganggu kualitas hidup dan kegiatan umum seseorang secara signifikan. Salah satu nyeri yang sangat tidak menyenangkan adalah nyeri gigi. Pengobatan selalu diarahkan kepada menjaga kebersihan mulut, memberikan analgesik, mengurangi inflamasi dan menambahkan antibiotik jika ada infeksi bahkan jika perlu dilakukan ekstraksi gigi. Cara lain dari pendekatan konvensional di atas adalah pasien dapat mempertimbangkan metode akupunktur. Akupunktur dilakukan dengan menusukkan jarum seukuran rambut manusia di sepanjang titik yang tepat di seluruh tubuh. Proses ini memicu aliran normal energi tubuh melalui jalur ekstra anatomi disebut meridian. Tujuan: Laporan kasus ini untuk menekankan adanya hubungan gigi-organ melalui jalur komunikasi di luar jalur komunikasi yang telah dikenal dalam anatomi. Kasus: Dua penderita dengan keluhan nyeri gigi geraham kanan bawah dilakukan terapi analgesia akupunktur oleh akupunkturis yang adalah dokter umum. Dalam kasus ini ditunjukkan bahwa rasa nyeri pada gigi dapat dihilangkan menggunakan teknik akupunktur. Tatalaksana kasus: Pasien dengan keluhan nyeri gigi, kasus #1 pada rahang bawah dilakukan terapi akupunktur pada titik Li-4 pada tangan dan kasus #2 pada titik Bl-25 pada pinggang. Pemilihan titik disesuaikan dengan keluhan pasien, menurut teori meridian dalam akupunktur. Nyeri berkurang sampai 90% dalam 40 detik. Kesimpulan: Keluhan nyeri pada gigi dapat dihilangkan menggunakan teknik akupunktur analgesia, menggunakan meridian sebagai jalur komunikasi di luar jalur komunikasi anatomi. Walaupun demikian perawatan kedokteran gigi pada penyebab nyeri yang utama adalah yang paling penting.

Dedifferentiation of MCF-7 Breast Cancer Continuous Cell Line, Development of Breast Cancer Stem Cells (BCSCs) Enriched Culture and Biomarker Analysis Ami Ashariati Prayogo; Andi Yasmin Wijaya; Winona May Hendrata; Steven Sheng Looi; Reny I’tishom; Lukman Hakim; Fedik Abdul Rantam; I Ketut Sudiana; Abdurachman Abdurachman
The Indonesian Biomedical Journal Vol 12, No 2 (2020)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v12i2.977

BACKGROUND: Cancer stem cells (CSCs) eradication might serve as a robust approach for cancer eradication. MCF-7 as breast cancer continuous cell line is known to contain breast CSCs (BCSCs) for its capability to maintain its original tumor population. CSCs enriched culture is a fundamental tool for CSCs targeted therapy development. Effective and unsophisticated CSCs dedifferentiation protocol for producing CSCs enriched culture is needed.METHODS: MCF-7 cells were cultured initially in Dulbecco's Modified Eagle Medium (DMEM) low glucose medium then changed to DMEM:F12. Serum starvation was performed during each medium refreshment gradually with fetal bovine serum (FBS) concentration of 10%, 5%, 2.5% until reaching 1% FBS concentration. Stable MCF-7 culture was then adapted to serum free culture system, containing DMEM:F12, epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), and B27 supplement as dedifferentiation protocol for 18 days. Cluster of differentiation (CD)44 and CD24 double staining immunocytochemistry was performed to evaluate cell stemness.RESULTS: The population of cells expressing BCSCs markers (CD44+/CD24low) in non-adherent single cells subpopulation was significantly increased after the dedifferentiation procedure (70.39%) compared to control groups (0.71%) (p<0.05). In contrast, the expression of BCSCs marker in adherent single cells subpopulation and for both adherent and non-adherent mammosphere the BCSCs markers showed a stable expression.CONCLUSION: BCSCs enrichment of breast cancer cell cultures from MCF-7 breast cancer cell line can be performed. Breast cancer cell plasticity is observed during the dedifferentiation protocol. Development of dedifferentiation inducing protocols can serve as an important foundation for breast cancer therapy development through BCSCs elimination.KEYWORDS: breast neoplasms, cell line, dedifferentiation, immunohistochemistry, neoplastic stem cells

Profile of Maxillofacial Fracture Patients at General Hospital in Surabaya Bonfilio Neltio Ariobimo; Marjono Dwi Wibowo; Abdurachman Abdurachman
Biomolecular and Health Science Journal Vol. 4 No. 1 (2021): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v4i1.26723

Introduction: Maxillofacial fractures can be caused by blunt trauma or sharp trauma. The purpose of this study was to identify the characteristics in patients with maxillofacial fractures who were treated in the Head and Neck Surgery Division of Dr. Soetomo General Academic Hospital, Surabaya during 2016.Methods: The research design was cross-sectional from patients with maxillofacial fractures. Those variables were evaluated are gender, age, type of etiology, site of maxillofacial fracture, gender and type of etiology based incidence, age and type of etiology based incidence. Data presented descriptively.Results: From 68 patients, consisted of 57 (83.82%) male, average age of 30.1 years old. The most common type of etiology was traffic accidents (92.64%), most common site of fractures were mandibular (33.33%), gender associated with the type of etiology was men who experienced traffic accidents (79.41%), and the age associated with the most types of events was ages 26-45 years with traffic accidents (47.05%).Conclusion: Maxillofacial fractures still become the problem that mainly cause is traffic accidents which occurred mostly in male and mandibular fracture as the most common site of fracture.

Optimal Diaphragmatic Breathing Patterns through Exercise Can Light Some Medical Problems Asmaul Lutfi Marufah; Hilmy Yafi Zuhair; Ulfi Qomariyah Hanum; Agus Rubiyanto; Astri Dewayani; Abdurachman Latief
Jurnal Respirasi Vol. 8 No. 2 (2022): May 2022
Publisher : Faculty of Medicine Universitas Airlangga

Breathing is an absolute human need. In an emergency, airway and breathing are the main problems that must be addressed immediately. Empirically, breathing techniques that people do in general are varied. Of all breathing patterns, it is believed that there must be the most optimal. One of them is diaphragmatic breathing (DB). DB plays the role of the diaphragm as the main muscle that performs the activity of inhaling and exhaling. Optimal breathing patterns, including certain DB, have the ability to relieve several medical problems. The aim of this study was to examine whether an optimal DB pattern could alleviate some medical problems. We conducted a literature study on 40 references consisting of 27 journals and 13 other appropriate literature sources. We searched library resources using the PubMed search engine through keywords: effectiveness of breathing, DB, and breathing exercises. Literature analysis was based on requirements, including inclusion and exclusion criteria. There were 26 journals which met the criteria. Optimal DB pattern can be a solution for chronic obstructive pulmonary disease (COPD), asthma, chronic stroke, congestive heart failure (CHF), gastroesophageal reflux disease (GERD), cerebral palsy (CP), labor pain management, and anxiety. It can be therapeutic to relieve some medical problems.

MODULATION OF BONE TISSUE HISTOMORPHOMETRY AND MALONDIALDEHYDE EXPRESSION LEVELS BY VITAMIN C IN RODENTS AFTER PRENATAL NOISE EXPOSURE Taya Elsa Savista; Viskasari Pintoko Kalanjati; Abdurachman Abdurachman
Buletin Farmatera Vol 4, No 2 (2019)
Publisher : Universitas Muhammadiyah Sumatera Utara

Abstract: Vitamin C is proposed as an antioxidant to combat the oxidative stress of prenatal noise exposure in bone tissue of newborn Wistar rats. Thirty-two Wistar mothers were administered oral vitamin C 150 mg/kg BW/day from D1 of pregnancy until delivery; white noise exposure of 95 dB, 4 hr/day was given from D15 of pregnancy until delivery. Newborn rats were divided into 4 groups equally (n=24): K1 (distilled water), K2 (vitamin C), P1 (distilled water + WN), P2 (vitamin C + WN). The osteoblast and osteoclast mean cell numbers, the osteoid volume, and an oxidative stress expression level marker of malondialdehyde (MDA) were calculated from two adjacent longitudinal slices of newborn rats’ tibiae using Cell Sense and ImageJ softwares (4 μ; 400x of light microscope magnification). Data were analyze using either ANOVA and LSD post-test or Brown-Forsythe and Games Howell post- test; significance level if p<0.05. In P2, the mean number of the osteoblast was significantly higher than in P1 (p<0.001); whilst the osteoclast mean number was significantly lower compared to other groups (p=0.03). In P2, the osteoid volume was significantly higher than in P1 (p=0.021); with lower MDA levels than P1 (p=0.074). From this study, vitamin C could protect the newborn rat bones exposed by prenatal noise as an oxidative stressor.Keywords: vitamin C, prenatal noise, osteogenesis, malondialdehyde

Electroencephalogram in Children who Experienced First Unprovoked Seizure Arinda Putri Auna Vanadia; Prastiya Indra Gunawan; Abdurachman Abdurachman; Martono Tri Utomo; Hanik Badriyah Hidayati
AKSONA Vol. 2 No. 2 (2022): JULY 2022
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (670.869 KB)

Highlight: Epiletiform abnormalities on the EEG provide additional clinical infromation about seizures The majority of patients who have a first unprovoked seizure have an abnormal EEG (Abnormal II). Using EEG as a supporting diagnostic tool in patients experiencing their first unprovoked seizures may provide more information to improve treatment ABSTRACT Introduction: The first unprovoked seizure is defined as a series of seizures that occur within 24 hours and are followed by recovery of consciousness with unknown triggering causes such as head trauma, central nervous system infections, tumors, or hypoglycemia. The first unprovoked seizure is a thing that cannot be underestimated. According to a previous study, less than half of those who experience their first unprovoked seizure will have another. An electroencephalogram (EEG) is one of the supporting examinations for the first unprovoked seizure. Objective: This study aims to determine the EEG as the first unprovoked seizure supporting examination. Methods: This is a retrospective, descriptive, observational study with sampling from the patient's medical record at Dr. Soetomo General Hospital Surabaya from January 2017 to December 2018 based on predetermined inclusion and exclusion criteria. Results: The EEG results in children who experienced their first unprovoked seizure were more abnormal (52.9%) than normal (47.1%), with an abnormal EEG breakdown of abnormal II (17.6%) and abnormal III (35.3%). There were no patients in this study who had EEG abnormal I. All patients with EEG abnormal II (17.6%) had an intermittent slow EEG waveform, while all patients with EEG abnormal III (35.3%) had a sharp waveform. The most common location of EEG wave abnormalities was temporal (55.6%). Conclusion: In the first unprovoked seizure, an EEG examination can assist clinicians as a seizure diagnostic assistant tool. It is hoped that the results of the EEG can provide better management of the first unprovoked seizure.

Pengaruh Shielding Aluminium Foil terhadap Perubahan Ketebalan Lapisan Epitel Kornea Akibat Paparan Radiasi Gelombang Elektromagnetik pada Tikus Wistar Jantan Dion K. Dharmawan; Viskasari P. Kalanjati; Abdurachman
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 7 No. 2 (2020): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universi
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v7i2.144

Ponsel telah diketahui memancarkan radiasi gelombang elektromagnetik (RGEM) yang digunakan sebagai media dalam telekomunikasi. Dampak buruk akibat paparan RGEM dapat terjadi pada lapisan epitel kornea mata yang secara anatomis terletak pada bagian anterior. Kami melakukan penelitian potensi aluminium foil (AF) sebagai perisai terhadap RGEM yang diukur dengan membandingkan ketebalan lapisan epitel kornea mata tikus kelompok kontrol dan perlakuan. Masing-masing tikus dimasukkan ke masing-masing kandang paparan secara terpisah. Sumber paparan RGEM berupa ponsel GSM 2100 (Taiwan) dengan SAR 0,84 – 1,86 W/kg yang tersambung wifi yang diletakkan di bagian bawah setiap kandang paparan tikus dengan paparan 4 jam /hari. Sejumlah 32 tikus dengan usia 2-3 bulan diacak dan dibagi menjadi 4 kelompok. Kelompok kontrol tanpa paparan RGEM terbagi menjadi K1 (tanpa pemberian AF) dan K2 (dengan pemberian AF). Sedangkan kelompok perlakuan yang diberi paparan RGEM terbagi menjadi P1 (tanpa pemberian AF) dan P2 (dengan pemberian AF). Hasil yang didapatkan bahwa kelompok P1 memiliki ketebalan lapisan epitel kornea paling tipis dibandingkan kelompok lainnya, namun secara statistik tidak signifikan (uji Kruskal Wallis; p value 0,147). Dari penelitian ini dapat disimpulkan bahwa, AF kemungkinan dapat menurunkan stres oksidatif yang memicu apoptosis pada lapisan epitel kornea mata dengan proses shielding sumber paparan RGEM.

Efektifitas Fraksinasi Kering pada Pengolahan Empulur Sagu dan Pemanfaatan Produk untuk Produksi Etanol abdurachman, Abdurachman; Noor, Erliza; Sunarti, Titi Chandra; Bantacut, Tajuddin; Tjahjono, Agus Eko; Musa, Musa
Jurnal Ilmiah Rekayasa Pertanian dan Biosistem Vol 12 No 1 (2024): Jurnal Ilmiah Rekayasa Pertanian dan Biosistem
Publisher : Fakultas Teknologi Pangan & Agroindustri (Fatepa) Universitas Mataram dan Perhimpunan Teknik Pertanian (PERTETA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jrpb.v12i1.599

Starch is more easily converted to sugars and fermented into ethanol. To increase ethanol productivity, a high-gravity fermentation method was developed. Sago trees are starch-producing that do not compete with food crops, but conventional processing has a negative impact on the environment. An alternative technology to minimize environmental impact is dry fractionation, product characteristics are suitable for ethanol production. Analysis of the effectiveness the processing of sago pith and the use of products for ethanol has never been published, so the analysis is carried out based on vertical differences in stem parts and determination of the optimum conditions of the ethanol production using sago starch-rich flour. Yield, starch recovery, starch ennrichment and shift starch are observational variables for the analysis of dry fractionation effectiveness. Starch-rich flour from the results of dry fractionation of each group of stem parts is mixed with a uniform composition and used as a fermentation medium. The one factor at a time (OFAT) experiment design was used to determine the effect of variables on optimal response, and verification is carried out. The distribution of starch granule size, starch content and parenchyma fiber characteristics can affect the effectiveness . Ethanol productivity showed optimum results at liquifaction 80oC for 60 minutes, using simultaneous saccharification and fermentation (SSF), high gravity fermentation and self-flocating yeast. The application of dry fractionation technology to obtain ethanol raw materials from sago trees has the potential to increase the added value of sago cultivation and the economic value of ethanol to be more competitive.

PAIN RELIEVED USING EXTRA ANATOMY PATHWAY IN ACUTE INFECTION Abdurachman, Abdurachman
Indonesian Journal of Tropical and Infectious Disease Vol. 3 No. 1 (2012)
Publisher : Institute of Topical Disease Universitas Airlangga

Acute infection is characterized especially by pain as major complaint of patients. In this following case report, it will be shown that pain cause of acute infection can be relieved using acupuncture technique. Acupuncture use meridian as extra anatomy pathway.

Kesamaan Elektromiogram pada Otot yang Memiliki Morfologi Mirip Tomas Marcelino A. Martin; Abdurachman Abdurachman; Subagyo Subagyo; Irfiansyah Irwadi
Majalah Kedokteran Indonesia Vol 72 No 4 (2022): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.72.4-2022-656

Introduction: Muscles are the largest tissue group in the body and can be classified into various classifications, one of which is based on their morphological shape. Examination of muscles, especially skeletal muscles, can use electromyography. The purpose of this study was to determine whether muscles that have similar morphology have no different electromyogram.Method: This is a descriptive observational study using needle electromyography. The sample amounted to 5 with five times MUP (Motor Unit Potential) in each musculus deltoideus and musculusResult: The mean amplitude, duration, number of voltage phases and the number of voltage turns off the musculus deltoideus and musculus gluteus medius in the study subjects were similar (p-value greater than 0.05).Conclusion: Muscles that have similar morphology in each parameter of amplitude, duration, number of voltage phases, and number of voltage turns do not have a significant difference in electromyogram.

Co-Authors Agus Ismanto Agus Rubiyanto Ahmad Sukandar Ami Ashariati Amiril Saridan, Amiril Andi Yasmin Wijaya Andianto Andianto, Andianto Andika Darmawan Wahono Arinda Putri Auna Vanadia Asmaul Lutfi Marufah Astri Dewayani Atika Atika Atika Atika Atsira, Olga Putri Bambang E. Suwito Bambang Purwanto Bambang Purwanto Barly Barly Bonfilio Neltio Ariobimo Chorisma Permata Putri Nurazizah Dian Eka Indriani, Dian Eka Dion K. Dharmawan Dominicus Martono, Dominicus Dzanuar Rahmawan Efrida Basri Erikavitri Yuliati Erliza Noor Farida Herry Susanty Fedik Abdul Rantam Hanafiah Hanik Badriyah Hidayati,* Mohammad Hasan Machfoed,* Kuntoro,** Soetojo,*** Budi Santoso,**** Suroto,***** Budi Utomo****** Hilmy Yafi Zuhair I'tishom, Reny Ida Lanniari, Ida Irwadi, Irfiansyah Jamal Balfas Jasni Jasni Khairina Khairina Krisdianto Sugiyanto Krisnawan A. Pradana Krisnawan Andy Pradana Lukman Hakim Luqman Hakim Andira Maramis, Margarita M. Maramis, Margarita Maria Marjono Dwi Wibowo Martono Tri Utomo Massofian Noor, Massofian Musa Musa Nurwati Hadjib Oktariza, Rury Tiara Olga Putri Atsira Prastiya Indra Gunawan Pratiwi, Wahyu Nur Rahmawan, Dzanuar S.Pd. M Kes I Ketut Sudiana . Saefudin Saefudin Sita Setyowatie SOETJIPTO . Steven Sheng Looi Subagyo Subagyo Sunarti, Titi Chandra Suwito, Bambang Edi Tajuddin Bantacut Taya Elsa Savista Tjahjono, Agus Eko Tomas Marcelino A. Martin Ujianto Ujianto Ulfi Qomariyah Hanum Viskasari P. Kalanjati Wahyu N. Pratiwi Winona May Hendrata Yudi Her Oktaviono, Yudi Her Yuliati, Erikavitri

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