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All Journal Science and Technology Indonesia JSFK (Jurnal Sains Farmasi & Klinis) JFIOnline Majalah Kedokteran Andalas Jurnal Pembelajaran Inovatif KOLOKIUM: Jurnal Pendidikan Luar Sekolah JPK: Jurnal Proteksi Kesehatan Journal of Pharmaceutical and Health Research Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks ARZUSIN: Jurnal Manajemen dan Pendidikan Dasar Kartika : Jurnal Ilmiah Farmasi Jurnal Kognisia
Rini Agustin
Universitas Andalas Padang
Religion Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Curriculum Management In Kapau Islamic Boarding Schools Agustin, Rini; Al Kadri, Hanif
KOLOKIUM Jurnal Pendidikan Luar Sekolah Vol 11, No 1 (2023): KOLOKIUM : Publisihing April 2023
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/kolokium.v11i1.576

Abstract

The problem in this study is related to the process of managing the curriculum and organizing the curriculum at Kapau Islamic Boarding School which has not been well planned, the level of supervision over curriculum management at Kapau Islamic Boarding School is still low. The purpose of this research is to look at curriculum management at Kapau Islamic Boarding School. This research is in the form of qualitative description. The research was conducted at the Islamic Boarding School Tarbiyah Ilamiyah Kapau Tilatang Kamang Kab. Agam. The techniques used to collect data in this study are observation, documentation, interviews. The results of the study show that Curriculum Management at Kapau Islamic Boarding School goes through a process or framework, which involves all institutional structures at Kapau Islamic Boarding School which are guided by the vision and mission of education, curriculum components, curriculum organization, curriculum implementation and control of curriculum implementation. Implementation of the curriculum at Kapau Islamic Boarding School uses two curriculum models, namely the madrasah curriculum which refers to the curriculum of the Ministry of Religion, and a special cottage curriculum for cottage lessons. The two curricula run separately in the education system at Kapau Islamic Boarding School. The madrasah curriculum is systematized, has documents and develops with reference to Islamic education curriculum standards from the Ministry of Religion, while the pondok (religious) curriculum refers to the teaching of kiyai/sheikh and does not have written curriculum documents using yellow books. So that the implementation and organization of the curriculum at Kapau Islamic Boarding School integrates one subject with another
Enhanced Piperine Solubility and Dissolution Rate in Piperine-Nicotinamide Multicomponent Crystal Adsorbed in Mesoporous Silica SBA-15 Fitriani, Lili; Fauziah, Gusrina; Hasanah, Uswatul; Agustin, Rini; Zaini, Erizal
Science and Technology Indonesia Vol. 11 No. 1 (2026): January
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2026.11.1.109-120

Abstract

Piperine, classified as a Class II substance in the Biopharmaceutics Classification System (BCS), has poor solubility in water but high permeability. This research aims to improve the solubility and dissolution rate of piperine by adsorbing a multicomponent crystal (MCC) of piperine-nicotinamide onto mesoporous silica SBA-15. Tetraethyl orthosilicate (TEOS) was used as a silica precursor and Pluronic P123 as a pore-formation template to create SBA-15. Adsorption of the MCC was carried out by solvent evaporation with MCC:SBA-15 mass ratio (1:1). Solid state characterization was carried out by nitrogen adsorption-desorption isotherm, X-ray powder diffraction (XRPD), differential scanning calorimetry (DSC), Fourier-transform infrared (FT-IR) spectroscopy, and scanning electron microscopy (SEM). Solubility tests were carried out for 24 hours and the dissolution rate profile was conducted for 60 minutes in distilled water. Dissolved piperine was determined using high performance liquid chromatography (HPLC) with methanol and distilled water as the mobile phase (75:25). The physical stability of MCC:SBA-15 was evaluated at various high relative humidities. The solid-state characterization results showed successful adsorption of the MCC in SBA-15 with a decrease in surface area, pore volume, and intensity of the X-ray diffraction peaks. The FT-IR spectrum of MCC:SBA-15 resembled that of SBA-15. The solubility test results showed 2.47-fold and 3.07-fold increases in solubility and dissolution rate compared to pure piperine, respectively. MCC:SBA-15 demonstrated high stability at 75% and 85% RH at 40◦C. In conclusion, adsorption of the MCC piperine-nicotinamide crystal in mesoporous silica SBA-15 can enhance the solubility and dissolution rate of piperine.
Pembentukan dan karakterisasi kristal cair aceklofenak untuk sistem penghantaran transdermal Mutiara Zulkarnaini; Erizal Zaini; Rini Agustin
JSFK (Jurnal Sains Farmasi & Klinis) Vol 12 No 1 (2025): J Sains Farm Klin 12(1), April 2025
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.12.1.81-91.2025

Abstract

Aceclofenac is a phenylacetic acid derivative classified as a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain caused by inflammation. It has potential for topical application through a transdermal delivery system. One promising approach is the use of liquid crystals as carriers in transdermal dosage forms. This study aims to develop a simple liquid crystal cream formulation for aceclofenac, using glyceryl monostearate as a mesogen and Pluronic as a stabilizer. The aceclofenac liquid crystal cream was characterized using Polarized Light Microscopy (PLM), Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy (ATR-FTIR), and Differential Scanning Calorimetry (DSC). Evaluations included drug release, permeation, viscosity, flow properties, zeta potential, and freeze-thaw stability. The optimal formulation consisted of oil: glyceryl monostearate–Pluronic P123: water in a 5:15:80% ratio. PLM results showed birefringence and a lamellar phase texture. FTIR analysis confirmed no new chemical bonds, while DSC indicated a reduced melting point and increased enthalpy of fusion. The release and permeation of aceclofenac after 6 hours were 27.849 ± 0.5479 µg/cm² and 21.093 ± 0.5761 µg/cm², respectively—higher than non-liquid crystal preparations. The cream exhibited thixotropic flow behavior, a zeta potential of -50.8 mV, and remained stable after six freeze-thaw cycles. In coclusion, Aceclofenac can be formulated into a liquid crystal cream with glyceryl monostearate as a mesogen, showing a birefringent lamellar phase that enhances its release and permeation
A Novel Postbiotic Patch Formulation Using Pediococcus acidilactici BK01 for Anti-Acne Applications Lidia Armayeni; Rini Agustin; Sri Melia; Adhitya Jessica
JSFK (Jurnal Sains Farmasi & Klinis) Vol 13 No 1 (2026): J Sains Farm Klin 13(1), April 2026
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.13.1.70-83.2026

Abstract

Acne is an inflammatory skin disorder often associated with infection by Cutibacterium acnes. Postbiotics in the form of cell-free supernatant (CFS) from Pediococcus acidilactici BK01 contain lactic acid, bacteriocins, and hydrogen peroxide, which exhibit potential antibacterial activity. This study aimed to formulate P. acidilactici BK01 CFS into a topical patch and evaluate its activity against C. acnes. Antibacterial activity and minimum inhibitory concentration (MIC) were determined using the well-diffusion method. The MIC (6.25%) was used to formulate patches via solvent-casting with HPMC K4M or PVA (2–4%) as polymers and glycerin, propylene glycol, or PEG 400 (0.2–0.6%) as plasticizers. The selected formulation was evaluated for antibacterial activity and physical characteristics. A combination of 4% PVA and 0.6% glycerin produced the best base and was used to prepare patches containing 6.25–75% CFS. The 65% CFS patch showed the highest inhibition against C. acnes ATCC 11827 (12.03 ± 0.373 mm), categorized as strong. The patch demonstrated acceptable organoleptic properties, thickness, folding endurance, pH, moisture content, and tensile strength. These findings indicate that the 65% CFS patch has potential as a topical anti-acne preparation.
Co-Authors Achmad, Rendy Alfiannoor Adhitya Jessica Akmal Djamaan Akrami, Hafizatul Al Kadri, Hanif Arta, Dwi Ramasepti Auzal Halim Auzal Halim Bilqis Nurganiyu Cecep Kustandi Diana Ariani Dwi Ramasepti Arta Edtyva Monicha Erizal Zaini Fajrin, Mutiara Izmu Fathya Intan Lestari Fathya Intan Lestari, Fathya Intan Fauziah, Gusrina Friardi Ismed Goeswin Agoes, Goeswin Lidia Armayeni Makhsura, Suri Marina Dwi Mayangsari Melia, Sri Muhsinin, Umil Mutiara Izmu Fajrin Mutiara Zulkarnaini Nova Syafni Novica Sari Putri, Fia Alifah Rahmadasmi, Nola Rahmaddiansyah, Refa Rahmi Nofita Rahmi Yosmar Rifma Rifma Rusmana Wijaya Setia Ningrat Saafrida Saafrida Sufyarma Marsidin Sulastri Sulastri T, Sasanti T, Sasanti Try Andy Sahputra Uswatul Hasanah Uswatul Hasanah, Uswatul Yolanda, Riri Prima