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All Journal Berkala Kedokteran Jurnal Surya Medika Jurnal Kajian Ilmiah Kesehatan Dan Teknologi (JKIKT) Jurnal Riset Kefarmasian Indonesia Indonesia Berdaya Journal of Pharmaceutical Care and Sciences Innovative: Journal Of Social Science Research Sains Medisina Majalah Cendekia Mengabdi Jurnal Farmasi SYIFA Jurnal Pengabdian Masyarakat Panacea
Malahayati, Siti
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P Penetapan Kadar Metilparaben Pada Krim Pemutih Wajah Yang Beredar Di Kecamatan Mentaya Hilir Utara Menggunakan HPLC (High Performance Liquid Chromatography) Sa'diyah, Halimatus; Rahmadani, Rahmadani; Malahayati, Siti
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 1 (2023): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i1.475

Abstract

Background: Based on the results of direct observations made by researchers in North Mentaya Hilir District, there are still many traditional markets or cosmetic shops that sell cosmetic products, especially whitening creams that have not been registered with BPOM and do not meet the requirements that have been set, and are indicated to contain methylparabens exceeding the maximum limit set by BPOM. Objective: To analyze the difference in methylparaben levels contained in BPOM registered and non-BPOM registered whitening cream preparations. Methods: Qualitative analysis was carried out by observing retention time, quantitative analysis using HPLC, and making comparisons to see the differences in levels contained in BPOM registered and non-BPOM registered face whitening cream preparations with parametric statistical tests Paired Sample T-Test. Results: The results of the study of BPOM registered and non-BPOM registered whitening creams were positive for containing methylparabens with the average levels contained in BPOM registered whitening cream samples A 0.19 ± 0.003% and samples B 0.79 ± 0.008%. While the levels contained in whitening creams are not registered with BPOM in sample A 0.18 ± 0.0005% and sample B 1.16 ± 0.066%. From the results of determining these levels, there is no difference in methylparaben levels contained. Conclusion: Whitening creams registered with BPOM and not registered with BPOM circulating in North Mentaya Hilir district contain methylparaben.
FORMULASI DAN UJI STABILITAS SEDIAAN TONER WAJAH EKSTRAK BUAH PARE (Momordica charantia L) SEBAGAI ANTI JERAWAT DENGAN VARIASI SURFAKTAN Noor, Muhammad; Malahayati, Siti; Nastiti, Kunti
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 1 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i1.330

Abstract

Bitter gourd extract (Momordica charantia L) contains secondary metabolites such as flavonoids, alkaloids, and saponins that can be antibacterial against acne-causing bacteria (Propionibacterium acnes). Momordica charantia L., could make into facial toner preparations to prevent the emergence and worsen acne. It is formulated with various concentrations of polysorbate 20 and performs stability testing. This study aimed at the optimal formula and analyzed the variations in the concentration effect of polysorbate 20 on the bitter gourd extract facial toner preparation. Bitter gourd extract would make into facial toner preparation with variations in the concentration of polysorbate 20. The accelerated stability test with the cycling test method includes before and after organoleptic, homogeneity, viscosity, and pH tests. The organoleptic stability result shows both stable formulas had the same liquid form, clear brown color, and characteristic rose odor. All formulations are stable on homogeneity, in which the particles are evenly mixed. The Formula I viscosity value is constantly stabilized and meets the parameters, while formula II is not but meets the parameters. The pH stability values of both formulas are stable and meet the parameters. Formula I is more optimal than formula II and the difference in surfactant concentration of polysorbate 20 has no effect on organoleptic, homogeneity, and pH but will affect viscosity.
Co-Authors Agustina, Ni Kadek Ayu Amelia, Norrahmi Aryzki, Saftia Aspia, Noor Auliyani, Nurul Bila, Widi Salsa Buih, Putri Helena Junjung Claudia, Yovi Dwi Salmarini, Desilestia Fitriah, Sita Hadhrianor, Hadhrianor Hikmah, Fitria Noor Husda Oktaviannoor, Husda Ira Wati, Nyoman Rindi Izma, Hayatun Karami, Muhammad Rian Al Nafis Kurniawati, Darini Liling Triyasmono Lubis, Lidya Ivana Larissa Maharani, Tri Anita Mayna, Mayna Melviani Melviani, Melviani Mia Audina, Mia Muhammad Ikhwan Rizki Muhammad Noor Nastiti, Kunti Nazhipah Isnani Norhabibah, Norhabibah Normaidah, Normaidah Noval Noval Novianty, Nadya Nugraha, Dyan Fitri Nur Mahdi NURUL HIDAYAH Perdana, Ratna Dewi Wulandari Putri Putri Vidiasari Darsono, Putri Vidiasari Putri, Lidia Risma Rachman, Muhammad Rezki Rahmadani Rahmadani Ramadhan, Puteri Wulan Ratnapuri, Prima Happy Sa'diyah, Halimatus Saftia Aryzki Samsul Hadi Sari, Putri Indah Setia Budi Sinta Dewi Tuti Alawiyah Wulan Ramadhan, Puteri Yuniarti, Ainun