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Comparison effect of cv 12, st 36 and st 40 ea on short term energy balance regulation in high fat diet rat Rejeki, Purwo Sri; Harjanto, Harjanto; Argarini, Raden; Subadi, Imam
Folia Medica Indonesiana Vol. 52, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

The aim of this study was to determine the comparative effects of EA (EA) on the CV12, ST36 and ST40 to weight gain prevention over the short-term regulation of energy balance. The study was conducted with a completely randomized design. Rats were divided into five groups: negative control group (no treatment, n=5), positive control (sham EA/back, n=5), EA CV 12 (n=6), EA ST 36 (n=6) and EA ST 40 (n=7). Rats were exposed to high-fat diet for two weeks and EA was simultaneously performed once daily, five days a week for two weeks with 2 Hz, for 10 minutes with continuous wave. Body weight, BMI, front limb circumference and rear were measured during study. Levels of blood glucose, cholesterol, triglycerides, LDL and HDL were measured at the end of the study; which reflects the short-term regulation of energy homeostasis. For weight loss, EA CV12, ST36 and ST40 group have lost weight significantly compared to the negative and positive control group. The ST40 group has a significant decrease than ST36 and CV12. The most significant decrease in BMI found in the ST40 group. EA did not affect blood glucose levels, but modulated blood lipid profile. In ST 40 group there was a significant decrease in cholesterol, LDL and triglycerides. EA at point ST 40 is potential in preventing increased body weight and BMI in rats exposed to high-fat diet compared to the CV 12 and ST 36. ST 40 is a point with a potential of lowering LDL and triglycerides serum so that it can play a role in the short term regulation of energy homeostasis but also in the prevention of dyslipidemia.
High Calorie Diet with a Combination of Intermittent Restriction Affects the Reproductive Cycle and The Uterine Weight of Mice (Mus Musculus) Kumalasari, Anggraeni Dyah; Herawati, Lilik; Argarini, Raden; Lukitasari, Lina; Othman, Zulhabri; Ningrum, Astika Gita
Folia Medica Indonesiana Vol. 57, No. 4
Publisher : Folia Medica Indonesiana

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Highlight: • High-calorie diet influence with interval restrictions combination on the reproductive cycle and weight of the uterus in mice were analyzed. • Calories balance impact for female reproductive health. Abstract : Balanced calories affected for body health and daily activities. Lose of energy can disturb the health and daily activities, while over calorie for diets also causes disorders such as metabolic. When there are excess calories in the body will be involved. It can be an obesity risk, diabetes mellitus, fertility disorder, cancer, and cardiovascular disease. Furthermore, in women there can be an increase in menstrual disorders and fertility disorder risk (Silvestris et al., 2018). This study aims to analyze highcalorie diet influence with interval restrictions combination on the reproductive cycle and weight of the uterus in mice. Experimental laboratory is a mouse (mus musculus) female's balb/c as object population. Sampling techniques using probability sampling with simple random sampling type. The study results on fisher's exact test gave a result of p > 0.05 so there was no significant difference between control group, high calorie diet group, and high calorie diet with interval restrictions group on the results of vaginal swabs /post-treatment reproductive cycle. The study outcome on robust tests between control, high calorie diet, and high calorie diet with interval restrictions groups. Obtained results (p < 0.05) that mean there are some significant discrepancies in the weight of uterine organ between groups. Calories balance in the body can impact female reproductive health.
IMPROVING PHYSICAL LITERACY AND EXERCISE AWARENESS FOR TEACHERS AND ELEMENTARY SCHOOL STUDENTS THROUGH THE CAKRAM RAGA TRAINING PROGRAM IN BANJARMASIN Argarini dr., M.Kes., Ph.D., Raden; Kinandita, Hayuris; Herawati, Lilik; Azmy, Ulul; Dirgantari, Rafi Arofah; Aji, Wahyu Renandi; Ramadhani, Laila
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 9 No. 4 (2025): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/.v9i4.2025.593-605

Abstract

An active society plays a crucial role in enhancing physical fitness, productivity, and overall quality of life. Data from the Ministry of Youth and Sports (Kemenpora) in 2023 indicated a steady decline in sports participation from 2021 to 2023. South Kalimantan ranks second lowest nationwide, with only 16.67% participation and an index score of 0.167. Furthermore, more than 77.13% of Indonesian children and adolescents aged 10 to 15 years were classified as having “low” or “very low” fitness levels. These conditions underscore the urgent need for health promotion through physical activity to support the Indonesia Emas 2045 vision. This community engagement program aimed to increase sports participation among school-age children in Banjarmasin through the innovative educational media CAKRAM RAGA (Sports Reference Disc) and educational videos. This educational media provides several options for physical exercise for children, allowing teachers and students to select a package of exercises for their daily exercise program. The training was conducted in the form of a seminar and workshop, during which participants were trained to use the CAKRAM RAGA media. The program took place on August 21–22, 2025, and involved physical education teachers, classroom teachers, and students, in collaboration with STIKES Suaka Insan Banjarmasin, with a total of 46 participants. Evaluation results demonstrated an improvement in participant knowledge regarding recommended physical activity, sport injury prevention, and nutrition for children, with the mean pre-test score increasing from 87.85 to 89.63 on the post-test. Although the improvement was only about 2%, it indicated that participants already had a strong baseline understanding, and the activities effectively reinforced existing concepts. Overall activity evaluation results showed that 98% of respondents strongly agreed that CAKRAM RAGA was easy to understand and use, while 94% strongly agreed that it was suitable for implementation in schools. Moreover, 98% expressed motivation to encourage daily student exercise after recognizing its importance. In conclusion, the implementation of the innovative educational media CAKRAM RAGA proved to be effective, user-friendly, and received highly positive feedback from participants. It is recommended that similar programs be expanded to more schools to broaden their benefits and promote an active, healthy generation in support of Indonesia Emas 2045.
A Biomolecular Review of the Effects of Weight-Bearing and Non-Weight-Bearing Exercise on Bone. Taena, Fauzan Syahru Ramadhan; Sari, Dewi Ratna; Argarini, Raden
Syifa'Medika Vol 16, No 2 (2026): Syifa Medika: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v16i2.10562

Abstract

Kerusakan tulang seperti osteopenia dan osteoporosis merupakan masalah kesehatan global yang prevalensinya terus meningkat, terutama pada wanita pascamenopause dan populasi lanjut usia. Aktivitas fisik berbeban (weight-bearing exercise) diketahui memberikan stimulus mekanik penting dalam mempertahankan homeostasis tulang, namun perbedaan mekanisme biomolekuler antara latihan weight-bearing dan non weight-bearing masih perlu dipahami secara komprehensif. Tinjauan ini bertujuan menganalisis secara mendalam perbedaan respons biomolekuler kedua jenis latihan terhadap regulasi remodeling tulang. Metode tinjauan dilakukan melalui evaluasi literatur ilmiah terbaru mengenai mekanotransduksi dan jalur sinyal terkait, termasuk Wnt/?-catenin, RANKL–RANK–OPG, MAPK/ERK, dan PI3K/Akt. Hasil kajian menunjukkan bahwa weight-bearing exercise menghasilkan tekanan aksial dan fluid shear stress tinggi yang menstimulasi integrin, Piezo 1, dan primary cilium pada osteosit, menurunkan sklerostin, serta mengaktifkan jalur Wnt/?-catenin yang meningkatkan diferensiasi osteoblas dan menekan osteoklas melalui peningkatan rasio OPG/RANKL. Aktivasi jalur MAPK/ERK dan PI3K/Akt juga memperkuat sintesis matriks tulang dan menjaga viabilitas sel. Sebaliknya, olahraga non weight-bearing hanya menimbulkan stimulus mekanik minimal sehingga aktivasi jalur anabolik tulang berlangsung parsial dan tidak meningkatkan densitas mineral tulang secara bermakna. Kesimpulannya, olahraga weight-bearing memberikan efek biomolekuler yang lebih kuat dalam mencegah kerusakan tulang dibandingkan olahraga non weight-bearing, sehingga layak dipertimbangkan sebagai strategi pencegahan osteoporosis yang efektif.