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All Journal Sport and Fitness Journal Majalah Kedokteran Bandung Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan JOURNAL SPORT AREA ANIMA Indonesian Psychological Journal Jurnal Layanan Masyarakat (Journal of Public Service) Folia Medica Indonesiana
Raden Argarini
Departemen Faal Fakultas Kedokteran Universitas Airlangga Surabaya
Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Comparison effect of cv 12, st 36 and st 40 ea on short term energy balance regulation in high fat diet rat Rejeki, Purwo Sri; Harjanto, Harjanto; Argarini, Raden; Subadi, Imam
Folia Medica Indonesiana Vol. 52, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

The aim of this study was to determine the comparative effects of EA (EA) on the CV12, ST36 and ST40 to weight gain prevention over the short-term regulation of energy balance. The study was conducted with a completely randomized design. Rats were divided into five groups: negative control group (no treatment, n=5), positive control (sham EA/back, n=5), EA CV 12 (n=6), EA ST 36 (n=6) and EA ST 40 (n=7). Rats were exposed to high-fat diet for two weeks and EA was simultaneously performed once daily, five days a week for two weeks with 2 Hz, for 10 minutes with continuous wave. Body weight, BMI, front limb circumference and rear were measured during study. Levels of blood glucose, cholesterol, triglycerides, LDL and HDL were measured at the end of the study; which reflects the short-term regulation of energy homeostasis. For weight loss, EA CV12, ST36 and ST40 group have lost weight significantly compared to the negative and positive control group. The ST40 group has a significant decrease than ST36 and CV12. The most significant decrease in BMI found in the ST40 group. EA did not affect blood glucose levels, but modulated blood lipid profile. In ST 40 group there was a significant decrease in cholesterol, LDL and triglycerides. EA at point ST 40 is potential in preventing increased body weight and BMI in rats exposed to high-fat diet compared to the CV 12 and ST 36. ST 40 is a point with a potential of lowering LDL and triglycerides serum so that it can play a role in the short term regulation of energy homeostasis but also in the prevention of dyslipidemia.
High Calorie Diet with a Combination of Intermittent Restriction Affects the Reproductive Cycle and The Uterine Weight of Mice (Mus Musculus) Kumalasari, Anggraeni Dyah; Herawati, Lilik; Argarini, Raden; Lukitasari, Lina; Othman, Zulhabri; Ningrum, Astika Gita
Folia Medica Indonesiana Vol. 57, No. 4
Publisher : Folia Medica Indonesiana

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Highlight: • High-calorie diet influence with interval restrictions combination on the reproductive cycle and weight of the uterus in mice were analyzed. • Calories balance impact for female reproductive health. Abstract : Balanced calories affected for body health and daily activities. Lose of energy can disturb the health and daily activities, while over calorie for diets also causes disorders such as metabolic. When there are excess calories in the body will be involved. It can be an obesity risk, diabetes mellitus, fertility disorder, cancer, and cardiovascular disease. Furthermore, in women there can be an increase in menstrual disorders and fertility disorder risk (Silvestris et al., 2018). This study aims to analyze highcalorie diet influence with interval restrictions combination on the reproductive cycle and weight of the uterus in mice. Experimental laboratory is a mouse (mus musculus) female's balb/c as object population. Sampling techniques using probability sampling with simple random sampling type. The study results on fisher's exact test gave a result of p > 0.05 so there was no significant difference between control group, high calorie diet group, and high calorie diet with interval restrictions group on the results of vaginal swabs /post-treatment reproductive cycle. The study outcome on robust tests between control, high calorie diet, and high calorie diet with interval restrictions groups. Obtained results (p < 0.05) that mean there are some significant discrepancies in the weight of uterine organ between groups. Calories balance in the body can impact female reproductive health.
A Biomolecular Review of the Effects of Weight-Bearing and Non-Weight-Bearing Exercise on Bone. Taena, Fauzan Syahru Ramadhan; Sari, Dewi Ratna; Argarini, Raden
Syifa'Medika Vol 16, No 2 (2026): Syifa Medika: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v16i2.10562

Abstract

Kerusakan tulang seperti osteopenia dan osteoporosis merupakan masalah kesehatan global yang prevalensinya terus meningkat, terutama pada wanita pascamenopause dan populasi lanjut usia. Aktivitas fisik berbeban (weight-bearing exercise) diketahui memberikan stimulus mekanik penting dalam mempertahankan homeostasis tulang, namun perbedaan mekanisme biomolekuler antara latihan weight-bearing dan non weight-bearing masih perlu dipahami secara komprehensif. Tinjauan ini bertujuan menganalisis secara mendalam perbedaan respons biomolekuler kedua jenis latihan terhadap regulasi remodeling tulang. Metode tinjauan dilakukan melalui evaluasi literatur ilmiah terbaru mengenai mekanotransduksi dan jalur sinyal terkait, termasuk Wnt/?-catenin, RANKL–RANK–OPG, MAPK/ERK, dan PI3K/Akt. Hasil kajian menunjukkan bahwa weight-bearing exercise menghasilkan tekanan aksial dan fluid shear stress tinggi yang menstimulasi integrin, Piezo 1, dan primary cilium pada osteosit, menurunkan sklerostin, serta mengaktifkan jalur Wnt/?-catenin yang meningkatkan diferensiasi osteoblas dan menekan osteoklas melalui peningkatan rasio OPG/RANKL. Aktivasi jalur MAPK/ERK dan PI3K/Akt juga memperkuat sintesis matriks tulang dan menjaga viabilitas sel. Sebaliknya, olahraga non weight-bearing hanya menimbulkan stimulus mekanik minimal sehingga aktivasi jalur anabolik tulang berlangsung parsial dan tidak meningkatkan densitas mineral tulang secara bermakna. Kesimpulannya, olahraga weight-bearing memberikan efek biomolekuler yang lebih kuat dalam mencegah kerusakan tulang dibandingkan olahraga non weight-bearing, sehingga layak dipertimbangkan sebagai strategi pencegahan osteoporosis yang efektif.
Pengaruh Olahraga Aerobik Tipe Closed Skill Terhadap Konsentrasi Mahasiswa Kedokteran Universitas Airlangga Andira, Dzulqarnain; Argarini, Raden; Maramis, Margarita Maria
Journal Sport Area Vol 4 No 1 (2019): June
Publisher : UIR Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25299/sportarea.2019.vol4(1).2195

Abstract

This research was conducted to determine the effect of using aerobic of closed-skill type toward students’ concentration of Pediatric Department of Universitas Airlangga. This research was experimental design which randomized pre-test post-test control group with 36 students who seldom doing sport as samples. These students were divided into two groups; experimental group and control group. Experimental group did aerobic with closed technique type training which medium to high intensity around 75 minutes a week for 3 weeks. On the otherwise, control group did not do it. The research instruments were xbox with kinetic sensor and attention network test. The students’ concentration was measured three aspects such as alerting, orienting and conflict effect. This analysis technique was done by using statistical technique through SPSS. The result shown that there was no significant different between experimental group and control group by comparing average score of pre-test and post-test for alerting aspect (0.895), orienting (0.572), and conflict effect (0.019). Therefore, there was significant different from pre-test and post-test of control group for conflict effect (0.019) but there were not significant different for alerting (0.072) and orienting (0.735) and for experimental group, there was significant different in alerting (0.02) and conflict (0.001) but there was not significant different for orienting effect (0.653). It can be concluded that there was not significant effect on students’ concentration between control group (0.778) and experimental group (0.571). It means that aerobic cannot influence students’ concentration.
Co-Authors Anggraeni Dyah Kumalasari Atsari, Nadhila Azmy, Ulul Choesnan Effendi Choesnan Effendi Dewi Ratna Sari Dzulqarnain Andira Etha Dini Widiasi HARJANTO HARJANTO Harjanto, J. M. HERAWATI, LILIK Hermawan Susanto Hesty Rohmatul Fajri Imam Subadi Indri Safitri Mukono, Indri Safitri Intan Anggun Pratiwi Irwadi, Irfiansyah Kumalasari, Anggraeni Dyah Lukitasari, Lina Made Pury Pratiwi Made Pury Pratiwi Margarita Maramis, Margarita Mayang Rizki Anggraeni Naesilla - Nancy M. Rehatta, Nancy M. Ningrum, Astika Gita Noer Halimatus Syakdiyah Othman, Zulhabri Rejeki, Purwo Sri Setiawan, Hayuris Kinandita Sudarno, Sudarno Sundari Indah Wiyasihati Taena, Fauzan Syahru Ramadhan Viskasari P. Kalanjati Wibi Riawan Wigati, Kristanti Wanito Zulhabri Othman