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Efikasi Terapi Topikal Kortikosteroid Ultrapoten, Solusio, dan Gel Timolol Maleat 0,5% Terhadap Hemangioma Infantil Superfisial Lukman Ariwibowo; Arief Budiyanto; Retno Danarti
Sari Pediatri Vol 17, No 6 (2016)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp17.6.2016.428-34

Abstract

Latar belakang. Terapi kortikosteroid ultrapoten menjadi terapi topikal standar untuk HI. Namun, kortikosteroid banyak efeksamping dan respon yang kadang gagal, perlu alternatif terapi topikal lain. Solusio dan gel timolol maleat 0,5% merupakan betabloker non selektif yang ternyata dapat menghambat proliferasi dan memicu regresi HI.Tujuan. Mengetahui efikasi terapi kortikosteroid topikal ultrapoten, solusio, dan gel timolol maleat 0,5% pada hemangioma infantilsuperfisial.Metode. Desain penelitian kohort retrospektif, dilibatkan 79 pasien HI superfisial dalam kurun waktu Januari 2011-Oktober 2015di RSUP. Dr. Sardjito, Yogyakarta.Hasil. Perbandingan selisih luas antara ketiga kelompok didapatkan perbedaan yang bermakna antara solusio timolol maleat 0,5%dibandingkan kortikosteroid ultrapoten 0,5% (p<0,001). Gel timolol maleat 0,5% dibandingkan kortikosteroid ultrapoten (p<0,001).Perbandingan antara selisih luas lesi setelah terapi solusio dan gel timolol maleat 0,5% tidak berbeda secara bermakna (p=0,744).Kesimpulan. Efikasi solusio dan gel timolol maleat 0,5% lebih baik dibandingkan kortikosteroid topikal ultrapoten terhadappengurangan luas lesi hemangioma infantil superfisial.
Pure Neural Leprosy Verdy Verdy; Arief Budiyanto; Agnes Sri Siswati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 27 No. 1 (2015): BIKKK APRIL 2015
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (285.927 KB) | DOI: 10.20473/bikk.V27.1.2015.70-76

Abstract

Background: Pure neural leprosy (PNL) is an infection by Mycobacterium leprae with clinical manifestation as nerve thickening, sensory nerve impairment, with or without motoric nerve involvement, and without skin lesion. Pure neural leprosy causes progressive degeneration of nerve function. Diagnosis establishement of PNL is difficult. Purpose: To discuss about PNL especifically in aspects of the diagnosis and therapy. Reviews: Gold standard in diagnosis of PNL is histopathological examination from nerve biopsy but this procedure is still difficult for various reasons. Some investigations can be done for PNL such as cytological fine needle aspiration, Mitsuda test, serology test for antibody anti-PGL1, electroneuromyography (ENMG), and polymerase chain reaction (PCR). Pure neural leprosy classification is based on findings of abnormality in neurological, immunological, and histopathological. Pure neural leprosy therapy is based on the classification of paucibacillary or multibacillary. Conclusions: The clinical and epidemiological findings plus with the electroneuromyography alteration were finally accepted as sufficient criteria to diagnose PNL. Pure neural leprosy therapy follows WHO regiment in accordance with the paucibacillary or multibacillary classification.Key words: pure neural leprosy, Mycobacterium leprae, nerve biopsy, anti-PGL-1, electroneuromyography.
Successful Treatment of Actinomycetoma with Combination of Cotrimoxazole and Tetracycline Verdy Verdy; Vina Ajeng Puspa Dewi; Arief Budiyanto; Agnes Sri Siswati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 27 No. 1 (2015): BIKKK APRIL 2015
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1047.729 KB) | DOI: 10.20473/bikk.V27.1.2015.77-83

Abstract

Background: Actinomycetoma is an infection of chronic granulomatous disease on the skin, subcutaneous tissue, fascia, and bone, occured after trauma because of bacteria innoculation. Clinical features seem painless nodules, abscess, fistula, and sinus  with granulated discharge.Gold standard treatment for actinomycetoma is cotrimoxazole. Combination therapy with other antibiotic is needed to prevent resistance and improve therapeutic efficacy. Purpose: To discuss successful treatment of actinomycetoma with combination of cotrimoxazole and tetracycline Case: A 19-years-old woman had complained of  chronic post-traumatic wounds since two years ago. Dermatological examination showed multiple painless nodules, sinus, and discharge on right dorsum pedis. Histopathological examination demonstrated sinus in dermis, suppurative granulomas, and SplendoreHoeppli phenomenon in dermis layer. Case Management: Combination therapy consist of cotrimoxazole 2x960 mg, that was given for 6 months and tetracycline 4x500 mg, that was given in the first 1 month.  No side effects and drug allergy during and/or post treatment was found. After clinical evaluation for 6 months, successful of treatment  was obtained and no recurrence was found. Conclusion: The combination therapy of cotrimoxazole for 6 months and tetracycline for 1 month was proven to be effective and no recurrence was found.Key words: actinomycetoma, cotrimoxazole, tetracycline.
Pengaruh Media Pembelajaran dan Kemandirian Siswa terhadap Hasil Belajar Mata Pelajaran PPKn SMK Via Medika Ciputat Budiyanto, Arief; Imbron, Imbron; Zaman, M. Badru
JIIP - Jurnal Ilmiah Ilmu Pendidikan Vol. 4 No. 3 (2021): JIIP (Jurnal Ilmiah Ilmu Pendidikan)
Publisher : STKIP Yapis Dompu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (481.785 KB) | DOI: 10.54371/jiip.v4i3.254

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Tujuan dari penelitian ini adalah mengetahui mengenai pengaruh dari pengaruh media pembelajaran dan kemandirian siswa terhadap hasil belajar mata pelajaran PPKn siswa. Metode dalam penelitian ini adalah menggunakan pendekatan kuantitatif dengan survey sebagai instrument penelitian. Data dikumpulkan dari 62 responden yang dijadikan sebagai sample jenuh. Hasil dari penelitian ini adalah media pembelajaran tidak berpengaruh terhadap hasil belajar mata pelajaran PPKn siswa hal tersebut dibuktikan dengan nilai Thitung yang lebih kecil dari Ttabel (-0,350<1,667). Sedangkan kemandirian siswa dalam penelitian ini, hal tersebut dibuktikan dengan nilai Thitung yang lebih besar dari Ttabel (4,189>1,667) dengan tingkat signifikan lebih kecil dari 0,05 (0,00<0,05) yang berarti sangat signifikan. Dan untuk hasil uji simultan pengaruh media pembelajaran dan kemandirian siswa terhadap hasil belajar mata pelajaran PPKn siswa terbukti berpengaruh, hal tersebut dibuktikan melalui nilai Fhitung yang lebih besar dari Ftabel (13,497>3,15) dengan tingkat signifikan (0,00<0,05) yang berarti sangat signifikan.
TECHNICAL ANALYSIS OF RIGID PAVEMENT AND FLEXIBLE PAVEMENT CALCULATIONS ON TEUKU UMAR ROAD – RAJAWALI ROAD Budiyanto, Arief; Muhammadun, Haris; Marleno, Risma
INTERNATIONAL JOURNAL ON ADVANCED TECHNOLOGY, ENGINEERING, AND INFORMATION SYSTEM Vol. 3 No. 4 (2024): NOVEMBER
Publisher : Transpublika Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55047/ijateis.v3i4.1270

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Road development in Sampang Regency is carried out based on the Vision and Mission of the 2019-2024 RPJMD, as stated in Mission point 3 Infrastructure: "Improving Quality and Sustainable Infrastructure Development." In 2023, the Sampang Regency Public Works and Spatial Planning Office reported that road stability was at 46.54% of the total length of 754.12 km of district roads. This research on the Teuku Umar Road - Rajawali Road Preservation project aims to analyze the calculation of rigid pavement construction thickness planning for a design life of 20 years, and flexible pavement construction using the Road Pavement Design Manual No. 02/M/BM/2017 method. The analysis of calculations for both rigid and flexible pavements uses the Road Pavement Design Manual Method No. 02/M/BM/2017 for a design life of 20 years. The results of this research indicate that the rigid pavement design includes 200 mm thick concrete, 100 mm skinny concrete, and 150 mm class A aggregate LPA. For the flexible pavement, the design includes 40 mm AC-WC Laston, 60 mm AC-BC Laston, and 400 mm class A aggregate LPA.
PENGARUH MEDIA SOSIAL TERHADAP MINAT BELI DAN KEPUTUSAN PEMBELIAN KONSUMEN: ANALISIS BIBLIOMETRIK Budiyanto, Arief; Pamungkas, Ibrahim Bali; Praditya, Alvin
Jurnal Ekonomi Manajemen Vol 8, No 2 (2022): November 2022
Publisher : Program Studi Manajemen Fakultas Ekonomi Universitas Siliwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37058/jem.v8i2.5468

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This study describes how the development of research on buying interest and purchasing decisions on social media, ranging from keywords that have a lot to do with the theme of the influence of social media on consumer behavior, and the number of publications in terms of timelines, to the trend of publications on social media research. All of them are summarized through bibliometric analysis of 73 journals that are used as references. In collecting journals, researchers use certain criteria and the sources used as references must be indexed into the SINTA (science and technology index) owned by the Ministry of Education and Culture with a SINTA limit of 2-6. It was found that Instagram is the most widely used social media research theme, and social media is widely used not only for transactions but also to be able to introduce products or services owned by marketers to potential consumers and is more directed to the branding process. The clothing and beauty products sector is the sector that is most widely discussed in the next social media research theme, which is the market and food and beverage sector.
Economic Empowerment through the Production of Fish Pellet, Organic Fertilizers from Maggots, and Catfish Nuggets from Budikdamber in Kronggahan Hamlet, Gamping, Sleman Sarastuti, Dewi; Suwito, Darwito; Budiyanto, Arief; Puspitasari, Ika; Alchusnah, Retno Hayati; Yusmiyati, Yusmiyati; Purnomo, Chandra Wahyu
Jurnal Pengabdian kepada Masyarakat (Indonesian Journal of Community Engagement) Vol 9, No 4 (2023): Desember
Publisher : Direktorat Pengabdian kepada Masyarakat Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpkm.82971

Abstract

Sleman Regency produces the biggest waste pile, approximately 701.95 tons/day, higher than the other districts in Yogyakarta Province (The Ministry of Environment and Forestry, 2020). National data show that unmanaged waste is 12.4% per year. This unmanaged waste has the potential to cause significant environmental and health problems. Efforts to minimize organic waste have been carried out by Kronggahan residents by utilizing waste bioconversion technology with black soldier fly (BSF) technology to produce maggot and kasgot. Maggot could be used for feeding fish and kasgot could be used for plant fertilizers. Kronggahan Hamlet has also developed several activities such as the, the development of aquaponics and budikdamber (budidaya ikan dalam ember-farming fish in buckets) where the feeding of catfish use maggot’s product. Harvested catfish and spinach from aquaponics and budikdamber can be processed into nuggets and could be added value for food security in Kronggahan Hamlet. This technology reduce organic waste by ± 70% by converted it into alternative fish feed that has economic value and high nutritional content. The purpose of this community empowerment activity was to increase community knowledge about maggot and maggot product proccessing from organic waste, foster knowledge in maintaining and improving health to prevent non communicable diseases. Hopefully, stakeholder can adopt policies in processing organic waste into maggot, the public can apply organic waste treatment and play a role in reducing the organic waste produced. The methods of implementing this program encompassed knowledge sharing, coordination and consolidation, preparation of educational media, and training packages that were integrated with other productive economic activities facilitated by Academic Hospital UGM’s community empowerment team in collaboration with Kronggahan Hamlet residents. Hopefully this program will be able to be publicized more broadly and can be duplicated in other regions.
Sikap Inovatif dan Kreatif Sebagai Dasar Jiwa Kewirausahaan Siswa Untuk Bersaing Dalam Era Digitalisasi Produk Budiyanto, Arief; Nurhadi, Ahmad; Masádi , Mahnun
Jurnal Peradaban Masyarakat Vol. 4 No. 4 (2024): Jurnal peradaban masyarakat (JPM)
Publisher : LPPM STIE Hidayatullah Depok

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55182/jpm.v4i4.485

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Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan pemahaman tentang pentingnya adaptasi dan peluang dalam kemajuan teknologi informasi untuk pemasaran dan bisnis pada umumnya. Tujuannya adalah untuk memahami penggunaan internet dan alat digital, menggunakan media sosial untuk pemasaran, dan membuat website agar bisa menjangkau lebih banyak pelanggan. Kegiatan ini dilakukan dengan metode ceramah, tutorial, dan diskusi. Materi yang disampaikan mencakup pengenalan internet dan alat digital, dengan tujuan agar siswa SMK memahami dan dapat menerapkannya dalam bisnis mereka nanti. Target materi ini tercapai dengan baik, yang terlihat dari pemahaman peserta melalui pertanyaan dan diskusi selama kegiatan. Namun, untuk mengimplementasikan hasil dari kegiatan ini, diperlukan kegiatan lanjutan. Tujuan dari kegiatan lanjutan ini adalah untuk memberikan pemahaman dan pengetahuan teknis sehingga peserta bisa lebih memahami digital marketing secara menyeluruh.
Pengaruh Social Media Marketing dan Store Atmosphere terhadap Keputusan Pembelian pada JKT Sneakers Bogor Cahyo, Rahmat Nur; Budiyanto, Arief
Cakrawala: Jurnal Ekonomi, Manajemen dan Bisnis Vol. 1 No. 4 (2024): Cakrawala: Jurnal Ekonomi, Manajemen dan Bisnis
Publisher : YAYASAN PENDIDIKAN MULIA BUANA (YPMB)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70451/cakrawala.v1i4.262

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh social media marketing dan store atmosphere terhadap keputusan pembelian Jkt Sneakers Bogor. Metode penelitian yang digunakan adalah metode asosiatif kuantitatif dengan pendekatan kuantitatif. Teknik sampel yang digunakan adalah Accidental Sampling, metode pengambilan sampel dengan menggunakan teori Rao Purba dengan taraf kesukaran 10%, maka diperoleh sampel sebanyak 98 responden. Analisis data menggunakan analisis regresi, analisis koefisien korelasi, analisis koefisien determinasi, dan uji hipotesis. Hasil penelitian ini adalah social media marketing dan store atmosphere berpengaruh positif dan signifikan terhadap keputusan pembelian dengan persamaan regresi Y = 3,906 + 0,570X1 + 0,346X2. Koefisien determinasi berpengaruh secara simultan 64%. Uji hipotesis secara parsial diperoleh angka social media marketing sebesar thitung sebesar 4,488 > ttabel 1,985. Dengan demikian maka Ho1 diterima dan Ha1 ditolak. Hal ini berarti tidak terdapat pengaruh dan tidak signifikan antara variabel inpenden yaitu social media marketing (X1) terhadap keputusan pembelian (Y). Store atmosphere sebesar thitung sebesar 2,706 > ttabel 1,985. Dengan demikian maka Ho2 ditolak dan Ha2 diterima. Hal ini menunjukan bahwa terdapat pengaruh yang positif dan signifikan antara variabel independen store atmosphere (X2) terhadap keputusan pembelian (Y). Uji hipotesis diperoleh nilai fhitung sebesar 84,404 > ftabel 3,09. Dengan demikian maka Ho3 ditolak dan Ha3 diterima, hal ini menunjukan bahwa secara bersama-sama berpengaruh positif dan signifikan secara simultan antara social media marketing (X1) dan store atmosphere (X2) secara simultan terhadap keputusan pembelian (Y).
Response of narrowband ultraviolet-B phototherapy combined with superoxide dismutase antioxidant cream in the management of non-segmental vitiligo Muchamad Apriyanto; Hanan Asrafi Noviandari; Niken Indrastuti; Arief Budiyanto
Indonesian Journal of Biomedicine and Clinical Sciences Vol 57 No 2 (2025)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v57i2.17224

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Vitiligo is a skin depigmentation disorder characterized by the loss of melanocyte function. The oxidative stress theory plays a role in the occurrence of vitiligo. Narrow band ultraviolet B (NB-UVB) phototherapy can be combined with other therapies to accelerate skin repigmentation. A 47 yo woman presented to the dermatology and venereology outpatient clinic in Dr. Sardjito General Hospital, Yogyakarta with a chief complaint of white patches on her face, neck, chest, and hands that had persisted for 11 yr. The patient had previously received NB-UVB phototherapy and a calcineurin inhibitor cream, but the symptoms persisted. Significant repigmentation of the lesion area was achieved after NB-UVB phototherapy combined with superoxide dismutase (SOD) antioxidant cream. NB-UVB phototherapy plays a role in immunomodulation, biostimulation, and reducing oxidative stress. The SOD helps clear superoxide radicals, preventing damage to melanocytes. The combination of NB-UVB phototherapy and antioxidant cream can be considered a treatment option for vitiligo.