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Pengaruh Susu Kuda Liar Sumbawa Terhadap Kadar TNF-a pada Tikus Gastritis yang Diinduksi Indometasin Musyarrafah, Musyarrafah; Wanadiatri, Halia; Merta, Putu Demas Ardina; Adnyana, I Gede Angga; Rozikin, Rozikin; Luktiana, Metha
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 6, No 4: December 2021
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (677.007 KB) | DOI: 10.30604/jika.v6i4.1031

Abstract

Gastritis is an inflammatory, irritating, or erosive condition that affects the mucosa submucosa of the stomach. Uncontrolled use of NSAIDs for a long time can cause excess stomach acid that will lead injury to the gastric lumen which results in the immune system release of pro-inflammatory factors, one of which is TNF-a. This study aims to determine the effect of Sumbawa’s mare milk (SMM) on TNF-a Levels in Wistar Rats with Indomethacin-induced gastritis. This study used 24 male Wistar rats which were divided into 4 treatment groups, namely negative control group (group 1), positive control group (group 2), SMM treatment group + Indomethacin (group 3), and SMM treatment group (group  4). Treatment was given for 14 days analyzed using an ELISA reader. Group 3 showed the highest levels of TNF-a (median=52.36). While group 4 got the lowest TNF-a level (median=24.49). In the control group, TNF-a levels were higher in group 1(median=35.14) than in group 2 (median=30.14). Results showed that SMM had a significant effect on TNF-a levels (p less than 0.05). Effects that can be given vary, either decreasing or increasing TNF-a depending on the conditions in the tissue. SMM has the potential not only as a preventive treatment but also as a curative treatment.Abstrak: Gastritis adalah kondisi inflamasi, iritasi, maupun erosif yang mengenai daerah mukosa dan submukosa lambung. Pemakaian NSAID yang tidak terkontrol dalam waktu lama dapat mengakibatkan asam lambung berlebih sehingga mukosa lambung terkikis. Perlukaan pada lumen lambung akan membuat sistem imun mengeluarkan faktor proinflamasi, salah satunya adalah TNF-a, sehingga terjadi gastritis. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian susu kuda liar Sumbawa terhadap kadar TNF-a pada Tikus Gastritis yang diinduksi Indometasin. Penelitian ini menggunakan 24 ekor tikus jantan galur Wistar yang dibagi menjadi 4 kelompok perlakuan yaitu kelompok kontrol negatif (kelompok 1), kelompok kontrol positif (kelompok 2), kelompok perlakuan SKL (Susu Kuda Liar) Sumbawa + Indometasin (kelompok 3), dan kelompok perlakuan SKL (kelompok 4). Perlakuan diberikan selama 14 hari dan dilakukan analisis menggunakan ELISA-reader. Kelompok 3 menunjukkan kadar TNF-a tertinggi (median=52,36). Sedangkan kelompok 4 mendapatkan kadar TNF-a terendah (median=24,49). Pada kelompok kontrol, kadar TNF-a lebih tinggi pada kelompok 1 (median=35,14) dibandingkan dengan kelompok 2 (median=39,74). Hasil penelitian menunjukkan bahwa susu kuda liar Sumbawa berpengaruh terhadap kadar TNF-a secara signifikan (p kurang dari 0,05). Pengaruh yang dapat diberikan beragam, baik menurunkan maupun meningkatkan kadar TNF-a tergantung dengan kondisi di jaringan tersebut. SKL Sumbawa tidak hanya berpotensi sebagai pengobatan preventif namun juga sebagai pengobatan kuratif.
Tolerance of Melon (Cucumis melo L.) Cultivar Melodi Gama 3 to Powdery Mildew Infection Rozikin, Rozikin; Daryono, Budi Setiadi
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 9, No 1: Jurnal Pembelajaran Dan Biologi Nukleus March 2023
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v9i1.3815

Abstract

Powdery mildew is one of melon disease caused by ascomycetes fungus from genus Sphaerotheca and Erysiphe. Breeding is considered to be the best approach to control Powdery mildew infection especially in melon. MG3 is a melon cultivar derived from ‘MG1’ x ‘Ladika’ and its estimate carry out resistant gene to Powdery mildew infection inherited from MG1. This research is to find out percentage and phenotype characters of Powdery mildew infection in MG3 compared to four commercial melons (Action 434, Glamour, MAI and ladika) that are popular in the market. Five melons are planted in greenhouse B of KP4 UGM. After five weeks, the plants where inoculated with Powdery mildew KP4 UGM in leaves. Scoring in three days after inoculation and the percentage of infections measured every 3 days for eight times using grid line 21 cm x 21 cm with small cubics 1,5 cm x 1,5 cm. The analysis of infections level in leaves, plant and population was done using Fukino protocol. The results show that cultivar MG3 tolerant and stable to Powdery mildew infection compare to cultivar Action 434, MAI and ladika in leaves, plant and population level. The infection of Powdery mildew caused damage to the leaves tissue, decreasing the abilities of photosynthesis resulting in necrotic, chlorotic and dead of the infected leaves. In fruits, infection causes break in the net, immature and rotten flesh, decrease sweetness and scent in cultivar Action434, MAI and Ladika. Base on microscopic analysis, Powdery mildew isolat KP4 UGM is a member of from genus Podosphaera.
The Role of Management School’s Committees in the Implementation of Public Elementary School Education Rozikin, Rozikin; Ahyani, Nur; Eddy, Syaiful
Journal of Social Work and Science Education Vol. 4 No. 1 (2023): Journal of Social Work and Science Education
Publisher : Yayasan Sembilan Pemuda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52690/jswse.v4i1.380

Abstract

The purpose of this research is to investigate the role of school committee empowerment management in a public elementary school unit in Plakat Tinggi District, Musi Banyuasin Regency. The qualitative descriptive technique is used in the research process, which includes observation, interviews, and documentation. The Chairperson/Management of the School Committee, Principal, Teachers, Parents/Guardians of Pupils, and Students from Plakat Tinggi District, Musi Banyuasin Regency served as research subjects. The findings (1) school committees have a planned program based on the school’s requirements, requests, and ideas; (2) In comparison to the program for establishing the Organizational Structure and Work Program, the program for producing the Statutes and Bylaws is pretty good. (3) The Empowerment Management of the School Committee as Fundraising and Educational Resources from the Community and in Following Up Aspirations, Ideas, Complaints, Suggestions, and Criticism from the Community and Student Guardians is quite good in relation to the School Committee fundraising and carrying out its functions and duties following up on complaints, suggestions, criticisms, and aspirations from students, parents/guardians, and the community.
Analysis of the Effectiveness of Digital Strategy in Increasing Product Sales with the EPIC Model Approach Rozikin, Rozikin; Mas'ud, M. Imron
JTI: Jurnal Teknik Industri Vol 10, No 2 (2024): December 2024
Publisher : Universitas Islam Negeri Sultan Syarif Kasim Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24014/jti.v10i2.31946

Abstract

This study aims to evaluate the effectiveness of digital strategy in increasing sales of hijab products at CV Age Group. This research uses market research methods to develop and implement a digital strategy focusing on social media and paid advertising campaigns without involving SEO (Search Engine Optimization) and SEM (Search Engine Marketing). Sales data was analyzed to assess the impact of this strategy on product visibility and sales performance. The results showed that the digital strategy successfully increased the visibility and sales of hijab products. Social media effectively reached a wider audience and improved customer interaction, while paid advertising increased sales. The findings of this implication confirm the effectiveness of digital strategies in marketing hijab products and the importance of strategy updates to maintain a competitive advantage. Keywords: Digital Strategy, Hijab Sales, EPIC Model, digital marketing, digital strategy effectiveness. 
Knowledge and Practice Managing of Liquid Organic Fertilizer from Waste in Tourism Village Bonjeruk, Central Lombok, West Nusa Tenggara Arjita, I Putu Dedy; Rozikin, Rozikin; Karmila, Dany; Utami, Sukandriani; Anulus, Ayu; Pratiwi, Made Rika Anastasia
Journal of Health Promotion and Behavior Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Garbage is a major issue in many countries throughout the world, including Indonesia. Every year, the amount of waste produced rises in tandem with population growth. As a result, it is vital to manage liquid fertilizer made from household waste, which will aid in the reduction of community problems. The general public still has little knowledge of how liquid fertilizer is made from household garbage. This study aimed to increase community understanding and practice through training and help in the processing of household trash into liquid organic fertilizer in the tourist village of Bonjeruk, Central Lombok, West Nusa Tenggara.Subjects and Method: This was a cross-sectional study conducted in the tourist village of Bonjeruk, Central Lombok, West Nusa Tenggara, from March to December 2021. A total of 27 subjects were selected in this study. The variables in this study were knowledge and behavior. The training in management household waste into organic liquid fertilizer was carried out for 4 months. The stages of intervention were as follows: 1) Education and simulation of sorting organic and non-organic waste; 2) Separating vegetable and fruit waste from rice, meat, and bone residue. Vegetable and fruit waste was transferred into composer barrels; 3) Spraying diluted bio-activator every time they enter organic waste; 4) Filling cans continuously with garbage; 5) Every 14th day, the liquid fertilizer can be harvested; 6) Liquid fertilizer can be used after being left for 14 days outside the composer barrel by dilution. The data were collected by questionnaire and analyzed descriptively.Results: After 4 months of training, the community was able to process liquid fertilizer from the use of compost barrel and natural bio-activators from household waste. Community knowledge related to liquid fertilizer after training (Mean= 91.48; SD= 11.12) was higher than before training (Mean= 85.56; SD= 12.57). Household waste management practice after training (Mean= 94.07; SD= 11.94) was better than before training (Mean= 45.93; SD= 22.32).Conclusion: Community knowledge and practice increase after going through training in processing household waste into liquid organic fertilizer in the tourist village of Bonjeruk, Central Lombok, West Nusa Tenggara.Keywords: organic liquid fertilizer, tourist village, household waste. Correspondence:Rozikin. Faculty of Medicine, Universitas Islam Al-Azhar. Jl. Unizar No.20, Turida, Kec. Sandubaya (83232), Kota Mataram, West Nusa Tenggara. Email: rozikin@mail.ugm.ac.id. Mobile: +62 878-2000-7449.Journal of Health Promotion and Behavior (2022), 07(04): 335-339DOI: https://doi.org/10.26911/thejhpb.2022.07.04.06
Peran Koperasi Unit Desa Cahaya dalam Peningkatan Ekonomi Petani Kelapa Sawit di Desa Sinunukan Kecamatan Sinunukan Kabupaten Mandailing Natal Provinsi Sumatera Utara Rozikin, Rozikin; Purwandari, Istiti; Listiyani, Listiyani
AGRIFITIA : Journal of Agribusiness Plantation Vol. 5 No. 1 (2025): MARET
Publisher : Program Studi Agribisnis INSTIPER Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55180/aft.v5i1.750

Abstract

Cooperatives are business entities owned and utilized by members. Cooperatives are business entities that aim to build and develop the economic capabilities of their members. This study aims to determine the types of services of the Cahaya Village Unit Cooperative in oil palm farmers' businesses and to determine the role of the Village Unit Cooperative in improving the economy of oil palm farmers in Sinunukan Village, Sinunukan District, Mandailing Natal Regency, North Sumatra Province. This research method was determined intentionally (purposively), namely the Cahaya Village Unit Cooperative (KUD) in Sinunukan Village. The method used in sampling was purposive sampling, by selecting active farmers. The data used in this study were primary and secondary data. The results of the study showed that the services of the Cahaya Village Unit Cooperative (KUD) in Sinunukan Village for oil palm farmers' businesses included the provision of production services, service services, savings and loan services, and marketing services. The Cahaya Village Unit Cooperative (KUD) in Sinunukan District plays a role in improving the economy of oil palm farmers
OPTIMALISASI MANAJEMEN HIPERTENSI PADA LANSIA DI WILAYAH PESISIR KAMPUNG MELAYU, AMPENAN NTB Rozikin, Rozikin; Adyana, Angga; Setyaningrum, Tri Wahyu; Widyaswara, Gravinda; Hapsari, Widie Kemala; Hayatillah, Raudhah
Jurnal Abdi Insani Vol 12 No 3 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i3.2208

Abstract

High blood pressure, also known as hypertension, is a medical condition that affects blood pressure and can lead to complications such as stroke and heart disease. Hypertension is suffered by many people living in coastal areas due to an unhealthy lifestyle and consuming salty fish. To reduce the number of people with hypertension in coastal areas, community service activities related to hypertension management were carried out. The methods used in the community service were problem identification with the Delbecq (non-scoring method) method, data collection through interviews with questionnaires and observations of 70 participants, problem intervention through poster counseling and tension checks, data analysis using univariate analysis. The results of the community service were dominated by 55 women (79%) and middle-aged (45-59 years) 46 people (66%). The results of the questionnaire search showed that as many as 60 people (86%) respondents had heavy physical activity, 39 people (56%) respondents had a good level of knowledge and hypertension management, 42 people (60%) were known to often consume salted fish and 48 people (69%) were found to have hypertension. The high rate of hypertension sufferers in the coastal area of Kampung Melayu is due to the lack of counseling that focuses on dietary management and increasing public awareness about the risk of hypertension related to the consumption of high-sodium foods.
Hubungan Tingkat Pengetahuan, Personal Hygiene, Dan Status Gizi dengan Kejadian Skabies Pada Anak Remaja di Panti Asuhan Nurul Jannah NW Ampenan dan Panti Asuhan Dharma Laksana Hindu Dharmawan, I Gede Kevin; Mirah Wulandari, Made Ayu; Rozikin, Rozikin; Aisyah, Icha
Action Research Literate Vol. 7 No. 12 (2023): Action Research Literate
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/arl.v7i12.229

Abstract

Skabies sering terjadi pada sekelompok orang yang tinggal bersama pada lingkungan dengan sanitasi buruk, terutama di daerah kumuh, pada kaum marginal seperti penghuni panti asuhan, penghuni penjara dan penghuni pondok pesantren. Penyakit ini paling tinggi terjadi di negara-negara tropis yang merupakan negara endemik penyakit Skabies. Apabila penyakit skabies ini tidak segera ditangani dengan baik, maka penyakit skabies akan mengakibatkan komplikasi berupa Impetigo dengan lesi (eritema, furunkulosis atau selulitis), Insomnia, dan infeksi sekunder (pioderma). Jenis penelitian yang digunakan adalah analitik observasional dengan menggunakan rancangan penelitian cross sectional study. Teknik pengambilan sampel menggunakan purposive sampling. Penelitian ini dilaksanakan di Panti Asuhan Nurul Jannah Nw dan Panti Asuhan Dharma Laksana, Kota Mataram. Data yang diperoleh dianalisis dengan uji chi-square. Batas nilai signifikansi adalah p-value <0,05. Hasil penelitian ini karakteristik responden sebagian besar didominasi oleh anak remaja usia 13-14 tahun, jenis kelamin laki-laki dan pendidikan SMP. Pada analisis bivariat didapatkan hasil masing-masing variabel (p-value <0,05) dengan nilai hubungan tingkat pengetahuan dengan skabies (0,0001), hubungan personal hygiene dengan skabies (0,0001), hubungan status gizi dengan skabies (0,0001), Untuk hasil analisis uji korelasi personal hygiene dengan skabies menggunakan Rank Spearman didapatkan kekuatan korelasi yang kuat, dengan nilai 0,590. Sedangkan untuk hasil analisis uji korelasi status gizi dengan skabies menggunakan Rank Spearman didapatkan kekuatan korelasi yang cukup, dengan nilai 0,508. Berdasarkan hasil uji statistik yang dilakukan, terdapat hubungan antara tingkat pengetahuan, personal hygiene, dan status gizi terhadap skabies pada Anak Remaja di Panti Asuhan Nurul Jannah Nw Ampenan dan Panti Asuhan Dharma Laksana
EFEKTIVITAS PEMBELAJARAN PRAKTIK PEMESINAN BUBUT MENGGUNAKAN PENDEKATAN STEM Rozikin, Rozikin; Abizar, Haris; Ikhsanudin, Ikhsanudin
Steam Engineering Vol. 7 No. 1 (2025): STEAM Engineering, Vol. 7, No. 1, September 2025
Publisher : Program Studi Pendidikan Teknik Mesin, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jptm.v7i1.18873

Abstract

21st century learning demands mastery of knowledge that connects science, technology, engineering and mathematics which play a major role as a learning reform towards 21st century learning. However, in the learning process, students are still not accustomed to connecting the four fields of exact sciences which are considered effective in addressing learning needs in the 21st century. The research aims to describe and describe the effectiveness of the STEM Approach that has been applied to learning lathe machining practices at SMK. This research was conducted at 13 vocational schools spread across Cilegon City, Serang City, and Serang Regency using the ex-post facto research method. Data were collected using Simple Random Sampling technique. A total of 32 samples of teachers who teach lathe machining techniques. The research instrument used a questionnaire that had validity and reliability testing. The results of testing the research hypothesis are the effectiveness and relationship between the use of the STEM approach and Lathe Machining Practice Learning. This is evidenced by the implementation of STEM declared “Good” and the effectiveness of STEM can be categorized as “Very Effective”. There is a relationship between the STEM variable (X) and the lathe machining variable (Y) by looking at the value in the T-test results which show that tcount 3.048> ttable 2.042 and significance <0.05, it can be concluded that there is an effectiveness of lathe machining learning using the STEM approach according to the specified hypothesis
Kejadian, Pengetahuan dan Sikap Terhadap Hipertensi Pada Warga Pesisir Pantai Dusun Montong Buwuh Desa Meninting NTB Rozikin, Rozikin; Musyarrafah; Setyaningrum, Tri Wahyu
Samota Journal of Biological Sciences Vol 2 No 1 (2023): Samota Journal of Biological Sciences
Publisher : University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjbios.v2i1.3162

Abstract

Dusun Montong Buwuh merupakan tempat produksi pengasapan dan pemindangan terbesar di desa Meninting. Mayoritas penduduknya 75% bekerja sebagai nelayan, dimana ditemukan angka prevalensi hipertensi dari data puskesmas meninting sangat tinggi pada daerah tersebut. Penelitian ini bertujuan untuk menelusuri kejadian, pengetahuan dan sikap terhadap hipertensi pada warga pesisir pantai montong buwuh. Metode yang digunakan yaitu: wawancara dengan kuesioner serta pengukuran tekanan darah terhadap 94 orang responden. Penentuan besaran sampel populasi menggunakan Slovin dengan taraf kepercayaan 0,005 (α = 5%) dan pengolahan data Univariat dengan spss. Hasil penelitian ini menunjukkan bahwa kejadian hipertensi pada warga didaerah wisata pesisir pantai montong buwuh relatif tinggi 63 orang (67.0%) hal tersebut karena warga dusun montong buwuh memiliki tingkat pengetahuan yang kurang tentang hipertensi 48 orang (51.1%), kurang dalam menyikapi hipertensi 70 orang (74.5%), serta kurang melakukan tindakan terhadap hipertensi 54 orang (57.4%). Akar penyebab masalah Hipertensi pada penduduk di Dusun Montong Buwuh yaitu kurangnya pengetahuan dan kesadaran masyarakat terkait hipertensi.