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All Journal Jurnal Farmanesia Journal of Innovative and Creativity Jurnal ABDIMAS MUTIARA Jurnal Medika STIKes Kesehatan Baru JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL
Marpaung, Jon Kenedy
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Engineering Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL

 1 
FORMULASI SEDIAAN SERBUK BERAS MERAH (Oryza sativa L.) SEBAGAI MASKER WAJAH Supartiningsih, Supartiningsih; Marpaung, Jon Kenedy; Laila, Asmuni
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 2 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Beras merah (Oryza sativa L.) bermanfaat bagi tubuh kita diantaranya zat besi, kalsium, protein, serat, kalium, lemak baik dan antioksidan. Salah satu bahan alami sebagai pelembab kulit dan masalah wajah kering adalah beras merah (Oryza Sativa L.). Tujuan dari penelitian ini adalah untuk mengetahui apakah beras merah dapat dibuat sebagai sediaan masker serbuk dan mengetahui formulasi sediaan serbuk beras merah yang memenuhi syarat evaluasi fisik sediaan. Pembuatan formula sediaan serbuk beras merah dilakukan dengan metode granulasi basah dengan bahan pengikat yang berbeda yaitu HPMC, Na.CMC dan Karbopol. Hasil penelitian pengujian organoleptik menunjukkan bahwa ketiga sediaan berwarna merah kream dan memilki beraroma khas beras merah, pada pengujian pH hasil yang didapat sangat bagus sesuai dengan pH kulit, yaitu 6. Ukuran partikel granul ketiga bahan pengikat memperoleh hasil 0,149 (mm), hasil kelembaban pengikat HPMC 9,284%, Na.CMC 10,489%, dan Karbopol 10,527%. Daya serap air bahan pengikat HPMC 9,6 ml/g, Na.CMC 7,3 ml/g, Karbopol 10,3 ml/g. Laju alir bahan pengikat HPMC 1,71 g/s, Na.CMC 1,51 g/s, Karbopol 5,17 g/s. Sudut istirahat bahan pengikat HPMC 23,27 , Na.CMC 18,65 , dan Karbopol 15,43 . Daya sebar pada pengujian HPMC 5,7 cm, Na.CMC 6,2 cm dan Karbopol 5,2 cm. Daya lekat pada pengujian HPMC 06,79 detik, Na.CMC 06,97 detik dan Karbopol 06,33 detik. Uji homogenitas pada ketiga bahan pengikat HPMC, Na.CMC dan Karbopol adalah homogenitas. Secara keseluruhan hasil pengamatan menunjukkan ketiga bahan pengikat baik digunakan untuk pembuatan sediaan masker serbuk beras merah.
Identifikasi Simplisia dan Uji Aktivitas Antibakteri Daun Ceremai (Phyllanthus acidus (L.) Skeels) Terhadap Bakteri Streptococcus pyogenes dan Bakteri Salmonella typhi Marpaung, Jon Kenedy; Suharyanisa, Suharyanisa; Situmorang, Manahan; Loi, Astina
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 4 No. 1 (2022): JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Uji Aktivitas Anti Bakteri Ekstrak Eteanol Kulit Bawang Merah (Allium cepa L.) Terhadap Bakteri Streptococcus mutans dan Pseudomonas aeruginosa Supartiningsih; Marpaung, Jon Kenedy; Dea Ananda Rizki
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 4 No. 2 (2022): JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Streptococcus mutans merupakan kontributor yang signifikan untuk kerusakan gigi. Pseudomonas aeruginosa salah satu bakteri Gram negatif yang paling sering diisolasi dari pasien di ruang ICU. Bawang merah memiliki senyawa aktif kuersetin yang berpotensi sebagai antibakteri. Penelitian ini bertujuan Mengetahui aktivitas ekstrak kulit bawang merah Merah (Allium cepa L.) terhadap bakteri Streptococcus mutans dan Pseudomonas aeruginosa dan mengetahui efektifitas konsentrasi ekstrak kulit bawang merah yang paling berpengaruh terhadap daya hambat pertumbuhan bakteri Streptococcus mutans dan Pseudomonas aeruginosa. Metode yang digunakan dalam penelitian ini adalah metode eksperimental secara uji untuk mengetahui aktifitas antibakteri ekstrak kulit bawang merah terhadap Streptococcus mutans dan Pseudomonas aeruginosa dengan konsentrasi 20%, 40%,60% dan dilakukan dengan metode difusi cakram. Penelitian ini dilakukan di Labolaturium Mikrobiologi Universitas Sari Mutiara Indonesia. Hasil dari penelitan menunjukkan bahwa simplisia kulit bawang merah mengandung fenolik, flavonoid, saponin, steroid/terpenoid dan alkaloid. Ekstrak etanol kulit bawang merah mempunyai aktivitas antibakteri.pada bakteri Steptococcus mutans dengan konsentrasi 60% (22,33 mm), 40% (18,66 mm), 20% (15,33 mm), kontrol positif (26,66 mm), kontrol negatif tidak memiliki zona hambat. Dan bakteri Pseudomonas aeruginosa dengan konsentrasi 60% (17,83 mm), 40% (15,83 mm), 20% (13,5 mm), kontrol positif (20 mm), kontrol negatif tidak memiliki zona hambat.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN PORANG (Amorphophallus oncophyllus Prain.) TERHADAP BAKTERI Escherichia coli DAN BAKTERI Salmonella typhi Marpaung, Jon Kenedy; Suharyanisa; Darwita Juniwati Barus; Putri
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 2 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Escherichia coli and Salmonella typhi are included in the pathogenic bacteria. These bacteria can cause infectious diarrheal diseases. Porang (Amorphophallus oncophyllus Prain.) leaves contain antibacterial compounds that are effective against bacterial growth. This study aims to determine the antibacterial activity of Porang leaf extract against Escherichia coli and Salmonella typhi bacteria and to determine the difference in antibacterial activity with the use of various concentrations of extracts on bacterial growth. Porang leaf extract was obtained by maceration method using 96% solvent. This test used the paper disc agar diffusion method with concentrations of 10%, 15%, 20%, and 25% against Escherichia coli and Salmonella typhi bacteria, positive control used chloramphenicol, and negative control DMSO, then tested using statistics using the ANOVA method. The results of the study on Escherichia coli bacteria obtained that the concentration and diameter of the inhibition zone with an average of three repetitions were 10% (9.41mm), 15% (11.4 mm), 20% (12.4 mm), 25% (13 .3 mm) and for Salmonella typhi, 10% (12.8 mm), 15% (13.6 mm), 20% (15.5 mm), and 20% (17.5 mm). In the positive control of chloramphenicol, the diameter of the inhibition zone was obtained with an average of three repetitions for each bacterium, namely Escherichia coli (27.5 mm) and Salmonella typhi (29.4 mm) while the DMSO negative control did not show any inhibition. The conclusion of this study showed that Porang leaf extract had activity against Escherichia coli and Salmonella typhi bacteria with strong criteria, seen from the increase in the concentration of the test solution had an increase in the diameter of the growth inhibition zone on bacteria,
Pembuatan Media Pertumbuhan Alternatif Pada Mikroorganisme Dengan Menggunakan Umbi Porang (Amorphophallus oncophyllus Prain) TERHADAP Staphylococcus aureus, Escherichia coli DAN Candida albicans Marpaung, Jon Kenedy; Purba, Sondang; Juniwati Barus, Darwita; Iqlima, Dara
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 4 No. 1 (2022): JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Porang tuber (Amorphophallus oncophyllus Prain) contains carbohydrates, fats, proteins, minerals, vitamins, and dietary fiber which are thought to be alternative growth media. This study aims to determine the growth of alternative media for microorganisms with Porang tubers. This research was conducted in the Pharmaceutical Chemistry laboratory, at Sari Mutiara University, Indonesia. Samples of Porang tubers were obtained from Porang plantations in the Amplas area, North Sumatra. This study uses an experimental method. Characterization of Porang tuber powder was found 9.54% water content, 9.09% water soluble extract content, and 1.43 total ash content.to contain%Secondary metabolites contained in Porang tuber starch were alkaloids and carbohydrates. The process of making starch begins with soaking with NaCl to remove the sap on the Porang tubers. Furthermore, the grating process is carried out until a precipitate of Porang tuber starch is found which will then be dried into Porang tuber starch. The manufacture of starch media respectively used a concentration of 5% (F1); 7.5% (F2) and 10% (F3). Then added agar, NaCl, and milk. Furthermore, microbiological tests were carried out using Staphylococcus aureus, Escherichia coli, and Candida albicans with the pour method. The comparison used is Nutrient agar and Potato dextrose agar. Furthermore, observations of the growth of these microorganisms were carried out. The results of the test Porang tuber starch showed yeast and bacteria growth media. The result of colony growth was found that the most colonies were found in formula 3 with Candida albicans as many as 297 colonies. The number of Staphylococcus aureus was found to be in formula 2 with 251 colonies, and for Escherichia coli, the most colonies were found in formula 3 with 143 colonies. Conclusion From the results of the study, it was found that Porang tubers can be used as growth media, Staphylococcus aureus, Escherichia coli, and Candida albicans.
Co-Authors Adiansyah Adiansyah, Adiansyah Ahmad ghazali, Ahmad Ayu, Herti Darwita Juniwati Barus Dea Ananda Rizki Dicky Yuswardi Wiratma Eka Margareta Sinaga Eriwaty Silalahi, Yosy Cinthya Fitri, Nadiatul Ginting, Jansen Asriel Girsang, Febriyantu Harefa, Karnerius Harun, Fatur Rahman Hutajulu, Johansen Hutauruk, Dumartina Iqlima, Dara Juniwati Barus, Darwita Komsary, Pauline Laila, Asmuni Loi, Astina Manik, Maria Partiwi Manurung, Kesaktian Marbun, Eva Diansari Mardianis, Mardianis Marpaung, Aditiya Baginda Munthe, Bernadetta R. Musyaawarah, Yanti Nasution, Pandapotan Nelson Simanjuntak Nurmela, Nuranti Purba, Sondang Purba, Yuni Kristina Purwandari, Vivi Putri Silitonga, Maringan Simanjuntak, Amsal Wahyu Maralus Simbolon, Lampita Putri Sinarsi, Sinarsi Sipayung, Inri Priskila Sitanggang, Rolastri Siti Maimunah Siti Nurbaya Sitorus, Carlos Salinas Sitorus, Panal Situmorang, Manahan Sofwan, Ahmad Gazali Suharyanisa Suhendri, Martin Supartiningsih Supartiningsih - - Syahfitri, Novita Thaib, Cut Masyithah Tiara Pratiwi, Tiara Turnip, Icha Wahyuni Vevariantina, Ayu Yanti, Roma Devina Yosy Cinthya Eriwaty Silalahi Yudhistira Yudhistira Zai, Andi Kristian Faatulo Zuhairiah Nasution, Zuhairiah