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Hasan, Nahrul
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Science Midwifery

 1 
Antibacterial Activity Test of Meniran Herb Extract (Phyllanthus Niruri L.) against Staphylococcus Epidermidis and Klebsiella Pneumoniae Nahrul Hasan Nahrul; Aprilya Sri Rachmayanti; Eem Masaenah
Science Midwifery Vol 10 No 5 (2022): December: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i5.927

Abstract

An antibacterial test of meniran herb extract (Phyllanthus niruri L.) against Staphylococcus epidermidis and Klebsiella pneumoniae has been carried out. Meniran herb powder was screened for phytochemicals to assess the secondary metabolites contained in it, then meniran herbs were extracted using the soxhletation method in stages with various solvents (n-hexane, ethyl acetate, and 70% ethanol). The disc diffusion method was used to test the inhibition zone diameter of n-hexane extract, ethyl acetate extract, and ethanol extract against Staphylococcus epidermidis and Klebsiella pneumoniae. Meniran herb extract was diluted with a concentration series using dimethylsulfoxide. Meniran herb extracts from the three types showed the best inhibition zone diameter when tested for minimum inhibitory concentration (MIC) by the solid dilution method. The results showed that meniran herb powder contained flavonoids, saponins, tannins, glycosides, and steroids/terpenoids. Antibacterial tests showed that ethyl acetate and 70% ethanol extracts had antibacterial activity only against Staphylococcus epidermidis. The antibacterial activity of the two meniran herb extracts had the largest inhibition zone diameter against Staphylococcus epidermidis at a concentration of 50%, which was 12,33 mm for the ethyl acetate extract and 16,00 mm for the ethanol extract. The MIC test of the ethanol extract of the meniran herb, which had the best antibacterial activity, found that at a concentration of 2,5% it was able to inhibit the growth of Staphylococcus epidermidis.
Antioxidant activity test of packaged juice variants of guava (psidium guajava L.) using FRAP (ferric reducing antioxidant power) method Aprilya Sri Rachmayanti; Nahrul Hasan; Suci Fitriani Sammulia; Henny Rachdiati; Yeni Febriyanti
Science Midwifery Vol 11 No 2 (2023): June: Midwifery and Health Sciences
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v11i2.1257

Abstract

Packaged juice are usually made using only one type of fruit or can be made using two types of fruits or other additional ingredients. Antioxidants are chemical compounds that can be used to protect biological components such as lipids, proteins, vitamins, and DNA. This study aims to determine the level of antioxidant activity in packaged juice drink variants of guava fruit using the FRAP (Ferric Reducing Antioxidant Power) method. The method used in this study is the FRAP method to test antioxidant activity. The results of testing the antioxidant activity with the FRAP (Ferric Reducing Antioxidant Power) method on the packaged juice drink samples, the level of antioxidant activity in juice drink sample A was 88,359 mgAAE/g sample, sample B was 88,202 mgAAE/g sample, sample C was 83,098 mgAAE/g sample, and sample D was 77,317 mgAAE/g sample. This shows that sample A demonstrated the highest antioxidant activity, followed closely by sample B, while samples C and D exhibited lower levels of antioxidant activity.
The relationship between knowledge and adherence to insulin therapy in type 2 diabetes mellitus patients at the outpatient clinic of Budi Kemuliaan Hospital, Batam City Rachmayanti, Aprilya Sri; Hasan, Nahrul; Sammulia, Suci Fitriani; Haryani, Reny; Suhaera, Suhaera; Meilanda, Rastria; Sinaga, Asmina
Science Midwifery Vol 11 No 5 (2023): December
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v11i5.1382

Abstract

Diabetes mellitus is a prevalent degenerative disease in today's society. Indonesia, as one of the countries with the largest population, has experienced a significant increase in the global prevalence of type 2 diabetes mellitus. Approximately 20% of the Indonesian population uses insulin with or without oral antidiabetic drugs. It has been found that patient compliance in Indonesia does not meet the recommended glycemic targets. This non-compliance is attributed to patients' lack of knowledge and understanding about insulin and its use in therapy. This study aims to explore the relationship between knowledge and adherence to insulin therapy among type 2 diabetes mellitus patients in the outpatient clinic of Budi Kemuliaan Hospital, Batam City. A descriptive correlation method was employed, utilizing a prospective cross-sectional research design. The sample was selected using purposive sampling, resulting in a total of 60 patients who met the inclusion criteria. Data were collected through two questionnaires: a knowledge questionnaire and the Medication Adherence Scale (MMAS). Statistical analysis included frequency distribution tests and chi-square tests. The research findings revealed a significant relationship between knowledge and adherence to insulin therapy, with a Chi-Square test yielding a P-Value of 0.029, where P-Value α < 0.05. In conclusion, this study demonstrates a significant correlation between knowledge and adherence to insulin therapy among type 2 diabetes mellitus patients. It is recommended that healthcare providers at Budi Kemuliaan Hospital deliver accurate information to patients to enhance their knowledge and understanding of insulin use, as well as the potential complications associated with diabetes mellitus.
Co-Authors Abdul Mun&#039;im Amelia, Ayu Annisa, Nabila Aprilya Sri Rachmayanti Aprilya Sri Rachmayanti Aprilya Sri Rachmayanti Ari Wahyudi ARI WAHYUDI Arie Voni Kartika Arie Voniekartika Azlina Anwar Charisman Gulo Chintia Wulandari Delladari Mayefis Delladari Mayefis Desy Maniarti Gusmali Dewi, Shinta Sari Diani Megasari Eem Masaenah Fareza, Muhamad Salman GHALIB SYUKRILLAH SYAHPUTRA, GHALIB SYUKRILLAH Habibie Deswilyaz Ghiffari Hanif Nasiatul Baroroh Haris, Restu Nur Hasanah Hayun Hayun Hayun Hayun HENDRI WASITO Henny Rachdiati Hesti Marliza Malik Mawarni Badar Meilanda, Rastria Mun'im, Abdul Nadia Sayyidadah Aulia Nia Kurnia Sholihat, Nia Kurnia Nur Wafiq Azizah Nurwijayanti Nuryanti Nuryanti Putri Khaerani Cahyaningrum Rachmayanti, Aprilya Sri Rastria Meilanda Reny Haryani Reny Haryani Reny Haryani, Reny Sammulia, Suci Fitriani Sari, Diani Mega Sari, Suci Wulan Sinaga, Asmina Sri Marlina, Sri Suci Fitriani Sammulia Suci Fitriani Sammulia Suci Fitriani Sammulia Suhaera Suhaera Suhaera Suhaera Suhaera, Suhaera Suhatri Suhatri Triyadi Hendra Wijaya Utami, Vitis Vini Fera Ratna Yeni Febriyanti Yunisa Friscia Yusri