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All Journal International Journal of Public Health Science (IJPHS) E-Jurnal Medika Udayana Biology, Medicine, & Natural Product Chemistry Jurnal Pengabdian Magister Pendidikan IPA Jurnal Kedokteran: Media Informasi Ilmu Kedokteran dan Kesehatan Jurnal Pengabdian Masyarakat Sains Indonesia (Indonesian Journal Of Science Community Services) JURNAL PENELITIAN PERAWAT PROFESIONAL JPMB: Jurnal Pemberdayaan Masyarakat Berkarakter Jurnal Pepadu Promotor: Jurnal Mahasiswa Kesehatan Masyarakat Acta Neurologica Indonesia Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Zubaidi, Fitriannisa Faradina
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Prospecting Marine Natural Products as the Disease-Modifying Treatment of Alzheimer’s Diseases Saputri, Legis Ocktaviana; Harahap, Herpan Syafii; Rivarti, Arina Windri; Zubaidi, Fitriannisa Faradina
Biology, Medicine, & Natural Product Chemistry Vol 13, No 2 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.132.433-441

Abstract

Alzheimer's disease (AD) is a severe and high costs health problem all over the world. To date, there is no therapy capable of curing AD, making drug discovery a challenging and intriguing field to explore. Targeting marine natural products (MNPs) as a source of drug leads is a suitable choice considering the content of bioactive compounds and promising pharmacological benefits. This article aims to look at MNPs with prospects in several prime targets in AD pathology to cure AD. Marine vertebrates (fishes), marine invertebrates (sponges, tunicates, ascidian, clams, scallops, sand dollars, crabs, cockle, sea cucumber, shrimp, bryozoa, marine worm), algae/seaweed, and marine microorganisms (marine fungi, bacterium, dinoflagellata, microalgae) can be potentially used as disease-modifying treatments (DMTs) for AD. By targeting multiple aspects of AD pathology, these MNPs offer a multifaceted approach to treating and potentially modifying the disease course. This result is an intriguing gap for researchers in the discovery and development of new drugs that can improve AD pathology.
Co-Authors Andhera, Athalita andi, Silmi chairan Anditiarina, Dasti Annafi, Muhammad Ibnu Ardiana Ekawanti Arjita, I Putu Dedy As’ad, Suryani Ayu Anulus Ayunda, Rahmah Dara Citranggana Prajnya Dewi Dany Karmila Deasy Irawati Dini Suryani, Dini Fachrudi Hanafi Faizah, Lillah Haq, Abiyyu Didar Herpan Syafii Harahap Hilam, Muhammad Ilsa Hunaifi, Ilsa Indrayana, Yanna Indrayana, Yanna Jaya Putra, Rian Akka Kadriyan, Hamsu Khairil Pahmi Lasmi, Anjely Doni Lestari, Diayanti Tenti Lina Nurbaiti, Lina Lysa Mariam Miraditi, Ni Komang Muhammad Abdurrosyid Munadi Munadi Musyarrafah, Musyarrafah Natsir, Rosdiana Ni Nyoman Ayu, Susilawati Nurhayati, Putri Nurhidayati Nurhidayati Nurhidayati Ocktaviana Saputri, Legis Rivarti, Arina Windri Rusdi, Yudika Ilhami Sahidu, Muhammad Ghalvan Umar, Husaini Utami, Herdiana Nurul Wiwin Mulianingsih Yudha Permana