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All Journal Jurnal Penelitian Kesehatan Suara Forikes THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Jurnal Kesehatan Prima Jurnal Ilmu dan Teknologi Kesehatan JURNAL PENELITIAN KESEHATAN Jurnal Analis Medika Biosains (JAMBS) JPP Jurnal Kesehatan Poltekkes Palembang Jurnal Ilmiah Tatengkorang Jaringan Laboratorium Medis Jurnal Teknokes Jurnal EduHealth International Journal of Advanced Health Science and Technology HEALTHY: Jurnal Inovasi Riset Ilmu Kesehatan Analis Kesehatan Sains (e-Journal) Jurnal Teknokes
Kartika Rahayuningsih, Christ
Department Of Medical Laboratory Technology Poltekkes Kemenkes, Surabaya
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Lead Levels in the Urine of Active Smokers and Passive Smokers in the Surroundings of Wadung Asri Sidoarjo Juliana Christyaningsih; Qonita Salsabilla Amara Sherly Amri; Christ Kartika Rahayuningsih
International Journal of Advanced Health Science and Technology Vol. 3 No. 4 (2023): August
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijahst.v3i4.286

Abstract

An active smoker is someone who smokes cigarettes, resulting in an impact on their health, as well as on passive smokers and the surrounding environment. Smoking exposes individuals to the risk of lead inhalation due to cigarette smoke. Accumulated lead from smoked cigarettes can pose a health risk. This study aimed to identify respondent characteristics and analyze lead levels in both active and passive smokers. The research employed a descriptive approach with quantitative analysis. The sample consisted of urine samples from 20 active and passive smokers in the vicinity of Wadung Asri, selected using purposive sampling. The study was conducted at the Toxicology Laboratory, TLM Department of the Health Polytechnic in Surabaya, and at BARISTAND from October 2022 to May 2023. Based on the characteristics of active and passive smokers, regarding age, those aged 21-44 accounted for 25% of active smokers and 30% of passive smokers, those aged 45-59 constituted 10% in both categories, and those aged 60-74 constituted 15% of active smokers and 10% of passive smokers. The study results revealed that lead levels in the urine of active smokers ranged from a high of 0.1592 µg/mL to a low of 0.0885 µg/mL. Conversely, in passive smokers, lead levels in the urine ranged from a high of 0.0885 µg/mL to a low of 0.000032 µg/mL. Thus, the conclusion drawn from this study is that one respondent exhibited lead levels exceeding the normal threshold of <0.15 µg/mL.
Perbandingan Pemeriksaan Skrining Antibodi (Indirect Coombs Test) dengan Direct Coombs Test pada Pasien dengan Riwayat Transfusi Darah Berulang Shela Yuni Arta; Suhariyadi Suhariyadi; Evy Diah Woelansari; Christ Kartika Rahayuningsih
Jaringan Laboratorium Medis Vol 7 No 2 (2025): November 2025
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v7i2.13643

Abstract

Repeated blood transfusions can increase risk of alloimmunization and autoimunization, which causes formation alloantibodies and autoantibodies. The presence of these antibodies can make cross-matching more difficult and increase the possibility of hemolytic transfusion risk. Antibody screening tests (Indirect Coombs Test) and Direct Coombs Test play a role in detecting the presence of alloantibodies and autoantibodies in patient with a history of repeated transfusion. The aim of the study was to determine the diferences in results between antibody screening (Indirect Coombs Test) and Direct Coombs Test in patients receiving repeated blood transfusions. This study used a quasi-experimental design with a cross-sectional approach. The subjects were patients with a history of blood transfusions more than 5 times at RSUD R.T. Notopuro Sidoarjo totalling 60 samples. The data obtained were then analyzed statistically to see if there were any significant differences between the two types of examinations. The results obtained showed a significant difference between the results of the antibody screening test (ICT) and the Direct Coombs Test (DCT) (p-value 0.000), that more patients with repeated blood transfusions had positive DCT results (75%). Some patients showed positive results on one or both types of tests, indicating the presence of alloantibodies or autoantibodies. ICT and DCT tests provide complementary information in detecting antibodies in patients with repeated transfusions. The use of both is important in improving the safety of blood transfusions and minimizing the risk of hemolytic reactions.
KORELASI HASIL UJI WIDAL DENGAN RAPID TEST IgG DAN IgM PADA PASIEN SUSPEK DEMAM TIFOID Fazira Azmi Haq; Evy Diah Woelansari; Christ Kartika Rahayuningsih; Wisnu Istanto
HEALTHY : Jurnal Inovasi Riset Ilmu Kesehatan Vol. 5 No. 4 (2026)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/healthy.v5i4.14121

Abstract

Typhoid fever is a systemic infectious disease caused by Salmonella enterica serovar Typhi and requires laboratory examinations to support diagnosis. The Widal test and IgG/IgM rapid test are serological examinations that are still widely used in healthcare facilities, but they have different test characteristics. This study aimed to analyze the correlation between Widal test results and IgG and IgM rapid test results in patients with suspected typhoid fever at Dr. H. Moh. Anwar Regional General Hospital, Sumenep. This study employed an analytical observational design with a cross-sectional approach and purposive sampling technique. The study was conducted from February 2 to 28, 2026, involving 35 patients with suspected typhoid fever. The examinations included the slide agglutination Widal test and immunochromatographic IgG/IgM rapid test. Data were analyzed using Spearman's correlation test with a significance level of p < 0.05. The results showed a significant correlation between the Widal test and the IgG rapid test, with a correlation coefficient of r = 0.667 and p < 0.001, indicating a strong positive correlation. A significant correlation was also found between the Widal test and the IgM rapid test, with r = 0.861 and p < 0.001, indicating a very strong positive correlation. In conclusion, there was a significant correlation between Widal test results and both IgG and IgM rapid test results in patients with suspected typhoid fever. These findings indicate an association between the results of the two serological examinations; however, their interpretation should consider the patient's clinical condition and the stage of disease progression. ABSTRAK Demam tifoid merupakan penyakit infeksi sistemik yang disebabkan oleh Salmonella enterica serovar Typhi dan memerlukan pemeriksaan penunjang untuk membantu diagnosis. Uji Widal dan rapid test IgG/IgM merupakan pemeriksaan serologis yang masih digunakan di fasilitas pelayanan kesehatan, tetapi memiliki karakteristik pemeriksaan yang berbeda. Penelitian ini bertujuan menganalisis korelasi hasil uji Widal dengan rapid test IgG dan IgM pada pasien suspek demam tifoid di RSUD Dr. H. Moh. Anwar Sumenep. Penelitian menggunakan desain observasional analitik dengan pendekatan cross-sectional dan teknik purposive sampling. Penelitian dilaksanakan pada 2–28 Februari 2026 dengan jumlah sampel sebanyak 35 pasien suspek demam tifoid. Pemeriksaan dilakukan menggunakan uji Widal metode slide aglutinasi dan rapid test IgG/IgM metode imunokromatografi. Data dianalisis menggunakan uji korelasi Spearman dengan tingkat kemaknaan p < 0,05. Hasil penelitian menunjukkan terdapat korelasi signifikan antara hasil uji Widal dengan rapid test IgG dengan koefisien korelasi r = 0,667 dan p < 0,001 yang menunjukkan hubungan kuat. Korelasi antara hasil uji Widal dengan rapid test IgM juga signifikan dengan r = 0,861 dan p < 0,001 yang menunjukkan hubungan sangat kuat. Dengan demikian, terdapat korelasi signifikan antara hasil uji Widal dengan rapid test IgG dan IgM pada pasien suspek demam tifoid. Hasil tersebut menunjukkan adanya keterkaitan antara hasil kedua pemeriksaan serologis, tetapi interpretasinya tetap perlu mempertimbangkan kondisi klinis dan fase perjalanan penyakit.
HUBUNGAN HEMOGLOBIN, TEKANAN DARAH, DAN HRV SEBAGAI PENANDA DINI RISIKO PENYAKIT JANTUNG PADA LANSIA Nadya Aulia Zulfa Mahardika; Christ Kartika Rahayuningsih; Evy Diah Woelansari
HEALTHY : Jurnal Inovasi Riset Ilmu Kesehatan Vol. 5 No. 4 (2026)
Publisher : Pusat Pengembangan Pendidikan dan Penelitian Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51878/healthy.v5i4.15546

Abstract

Cardiovascular risk increases among older adults as a consequence of aging, highlighting the need for physiological assessments that may support early risk identification. This study aimed to analyze the relationships of hemoglobin levels and systolic and diastolic blood pressure with Heart Rate Variability (HRV) as an indicator of autonomic nervous system function among older adults attending the Elderly Health Post in Sumber Kemuning Tengah Village, Bondowoso. An observational analytical study with a cross-sectional design was conducted involving 38 older adults selected through purposive sampling. Hemoglobin levels were measured using a hematology analyzer, blood pressure was assessed with a digital sphygmomanometer, and HRV was evaluated using the Standard Deviation of Normal-to-Normal Intervals (SDNN) and Root Mean Square of Successive Differences (rMSSD). Associations were analyzed using Spearman's correlation test. The results showed that 76.3% of respondents had normal hemoglobin levels, while 94.7% had elevated systolic blood pressure and 71% had elevated diastolic blood pressure. Low SDNN values were observed in 63.2% of respondents, whereas 39% had high rMSSD values. No statistically significant associations were found between hemoglobin levels or systolic and diastolic blood pressure and either SDNN or rMSSD (p > 0.05). These findings indicate that significant relationships among the assessed parameters were not identified in the study population. Further studies involving larger samples and adjustment for potential confounding factors are needed to clarify these relationships and their implications for cardiovascular risk assessment in older adults. ABSTRAK Risiko penyakit kardiovaskular pada lansia meningkat seiring proses penuaan, sehingga diperlukan pemeriksaan parameter fisiologis yang dapat mendukung identifikasi dini risiko tersebut. Penelitian ini bertujuan menganalisis hubungan kadar hemoglobin dan tekanan darah sistolik maupun diastolik dengan Heart Rate Variability (HRV) sebagai gambaran fungsi sistem saraf otonom pada lansia di Posyandu Lansia Desa Sumber Kemuning Tengah, Bondowoso. Penelitian menggunakan desain analitik observasional dengan pendekatan cross-sectional. Sebanyak 38 lansia dipilih menggunakan teknik purposive sampling. Kadar hemoglobin diperiksa menggunakan hematology analyzer, tekanan darah diukur dengan sfigmomanometer digital, sedangkan HRV dinilai berdasarkan parameter Standard Deviation of Normal-to-Normal Intervals (SDNN) dan Root Mean Square of Successive Differences (rMSSD). Analisis hubungan dilakukan menggunakan korelasi Spearman. Hasil menunjukkan bahwa 76,3% responden memiliki kadar hemoglobin normal, sedangkan 94,7% mengalami tekanan darah sistolik tinggi dan 71% mengalami tekanan darah diastolik tinggi. Sebanyak 63,2% responden memiliki SDNN rendah, sementara 39% memiliki rMSSD tinggi. Tidak ditemukan hubungan yang signifikan antara kadar hemoglobin maupun tekanan darah sistolik dan diastolik dengan SDNN dan rMSSD (p > 0,05). Temuan ini menunjukkan bahwa hubungan antarparameter tersebut belum teridentifikasi secara signifikan pada responden yang diteliti. Penelitian lanjutan dengan jumlah sampel lebih besar dan pengendalian faktor perancu diperlukan untuk memperjelas keterkaitan parameter tersebut dengan risiko kardiovaskular pada lansia.
Co-Authors ., Pestariati Anggraini, Anita Dwi Aprilia Irmawati Aprilyadi, Nadi Astuti Setiyani, Astuti Ayu Puspitasari Ayu, Puspitasari Bambang Hadi Sugito Cholidah, Ema Zahiroh Nur Darjati Dedi Kurniawan Demes Nurmayanti Devi Puspitasari Devi Puspitasari Dewi, Luh Putu Rahayu Candra Edy Haryanto Embun Sari Fadhila Endah Astuti, Sri Sulami Endarini, Lully Hani Endarini, Lully Hanni Evi Yunita N Evy Diah Woelansari Fadhila, Embun Sari Fazira Azmi Haq Febri, Fitra Nur Fitra Nur Febri Fridayanti, Ni Made Risma Hadi Suryono Handayati, Anik Iis Rofiatul Ana Indah Lestari Indah Lestari Indah Lestari Indah Lestari, Indah Indah, Lestari Indira Ayuni Sri Pramasti Inggit Rianingtyas Ira Puspita Sari Isfentiani, Dina Istanto, Wisnu Juliana Christyaningsih Khambali, Khambali Kiaonarni OW Lembunai Tat Alberta, Lembunai Tat Luh Putu Rahayu Candra Dewi Maruni Wiwin Diarti Maruni Wiwin Diarti Mutiarawati, Diah Titik N. S. Widodo Nadya Aulia Zulfa Mahardika Nuning Marina Pengge Nur Hatijah Puspita Dewi, Teresia Retna Qonita Salsabilla Amara Sherly Amri Ramadhany, Rieke Dwi Rieke Dwi Ramadhany Riya Agustin Sasongkowati, Retno Shela Yuni Arta Siagian, Hotmaida Siti Alfiah Suhariyadi Suliati Suliati Sumasto, Hery Tacik Idayanti Vernanda Arsya Nabilla Widiastutik, Dyah Winarni Winarni Yunarsih, Yunarsih Yusianti Silviani