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Pengaruh Pemberian Formula Daun Sirih Cina dan Jahe Merah terhadap Kadar LDL dan Trigliserida pada Tikus Obesitas Bintanah, Sufiati; Saraswati, Retno Arra; Al Sa’diyah, Imtiyaz Halimah; Ayuningtyas, Rr. Annisa
Nutriology : Jurnal Pangan, Gizi, Kesehatan Vol. 6 No. 2 (2025): Oktober 2025
Publisher : Program Studi Gizi, Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/nutriology.v6i2.5509

Abstract

Obesity is a condition characterized by excessive fat accumulation and is associated with elevated levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the blood. A combination of herbal ingredients such as Chinese betel leaf (Peperomia pellucida L.) and red ginger (Zingiber officinale var. rubrum) is known to contain flavonoids and gingerol, which play a role in reducing blood lipid levels. This study aimed to evaluate the effect of a formulation of Chinese betel leaf and and red ginger on LDL and triglyceride levels in obese male Sprague Dawley rats.. This study was conducted using a true experimental design with a pretest-posttest control group approach. A total of 30 rats were divided into five treatment groups, including a control group and three intervention groups (P1: Chinese betel leaf, P2: red ginger, and P3: a combination of both). The results showed that the combination of 88 mg Chinese betel leaf and 115.5 mg red ginger significantly reduced LDL levels by 57.94% and triglyceride levels by 41.09% (p < 0.05). Conclusion is the combination of Chinese betel leaf and red ginger simplicia was effective in lowering blood lipid levels in an obese rat model.
PENGARUH PEMBERIAN FORMULA KOMBINASI AIR JERUK NIPIS (Citrus aurantifolia) DENGAN TEPUNG DAUN KELOR (Moringa oleifera) TERHADAP KADAR LEUKOSIT PADA TIKUS SPRAGUE DAWLEY (Rattus norvegicus) DISLIPIDEMIA Bintanah, Sufiati; Sari, Dewi Kartika; Latrobdiba, Zahra Maharani; Nadia, Fika Shafiana
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 46 No. 2 (2023): PGM VOL 46 NO 2 TAHUN 2023
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36457/pgm.v46i2.769

Abstract

Dyslipidemia can trigger inflammation that affects the activity and number of leukocytes. Inflammation can be improved with foods that contain anti-inflammatories such as lime and Moringa leaf powder. This study aims to determine the effect of giving a combination formula of lime juice and moringa leaf powder on leukocyte levels in dyslipidemic Sprague Dawley rats. Experimental study with Randomized Pre and Post Test with Control Group Design. Samples were divided into 4 groups P0 (control group), P1 (2.25 ml lime + 0.2 g moringa), P2 (1.57 ml lime + 0.26 g moringa) and P3 (2.92 ml orange lime + 0.14 g moringa) were given intervention for 21 days. The results showed that there was no significant decrease in leukocyte levels after being given intervention in each group with a p-value> 0.05. So it can be concluded that giving the combination formula did not affect the decrease in leukocyte levels.
Peningkatan Pengetahuan Dan Ketrampilan Pembuatan Sari Pebren Tanpa Limbah Pada Ibu-Ibu Aisyiyah Kowangan Bintanah, Sufiati; Ulvie, Yuliana Noor Setiawati; Rohman, Abdul
JURNAL INOVASI DAN PENGABDIAN MASYARAKAT INDONESIA Vol 2 No 1 (2023): Januari
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jipmi.v2i1.71

Abstract

Latar belakang: Pandemi covid 19 tidak hanya berdampak pada kesehatan masyarakat akan tetapi juga berdampak terhadap perekonomian, pendidikan dan juga kehidupan sosial pada masyarakat. Banyak keluarga yang kehilangan pendapatan karena banyaknya pemutusan hubungan kerja sehingga membutuhkan ketrampilan berwirausaha bagi para ibu rumah tangga untuk menumbuhkan ekonomi keluarga. Sari pebren merupakan minuman sehat dengan bahan dasar tempe kedelai dan rice bren yang dibuat tanpa limbah yang berpotensi untuk meningkatkan ekonomii keluarga. Tujuan:  Meningkatkan pengetahuan dan ketrampilan ibu-ibu Aisyiyah Kowangan dalam Pembuatan sari pebren tanpa limbah. Metode: Kegiatan ini dilakukan dalam bentuk pelatihan dengan materi teori dan praktik. Keberhasilan kegiatan diukur berdasarkan penilaian pre-test dan post-test. Hasil: Pengetahuan partisipan dalam pembuatan pebren meningkat sebesar 95.12%, pengetahuan pembuatan label meningkat sebesar 83.72%, pengetahuan pemasaran digital meningkat sebesar 77.5%, pengetahuan pengurusan NIB meningkat 87.7%, pengetahuan pengurusan sertifikat halal meningkat 84.44%. Hasil evaluasi praktik yang dilakukan baik pada tahap persiapan, proses pengolahan, penyajian maupun kreatifitas sebagian besar kelompok mendapatkan nilai lebih dari 80, artinya semua kelompok melakukan praktik dengan baik sesuai arahan pembimbing saat demonstrasi dilakukan. Evaluasi terhadap potensi sari pebren 84% dalam kategori baik. Partisipan menyatakan bahwa kegiatan sangat bermanfaat sebesar 66%, sisanya sebesar 34% mengatakan bermanfaat untuk meningkatkan ekonomi keluarga. Kesimpulan: Pembuatan sari pebren tanpa limbah sangat bermanfaat bagi ibu-ibu Aisyiyah Kowangan untuk meningkatkan ekonomi keluarga. Kata Kunci: aisyiyah kowangan, ketrampilan, pengetahuan, sari pebren tanpa limbah ________________________________________________________________________________________ Abstract Background: The covid 19 pandemic impacts public health and the community's economy, education and social life. Many families have lost their income due to the many layoffs, thus requiring entrepreneurship skills for housewives to grow the family economy. Sari Pebren (Tempeh Rice Bran) is a healthy drink with the basic ingredients of soybean tempeh and bran rice which is made without waste and can improve the family's economy. Aisyiah is a women's activity group with recitation, entrepreneurship, and health activities. Objective: to increase the knowledge and skills of Aisyiyah Kowangan women in making Pebren juice without waste. Method: This activity is carried out through theoretical and practical training. Activity assessment is based on pre-test and post-test assessments. Result: Based on the evaluation results, increased knowledge by 95.12%, participants increased their knowledge in the process of making Pebren by 83.72%, participants increased label making by 7.5%, participants increased knowledge in digital marketing, 87.7% there was an increased knowledge in the management of NIB and 84.44%, increased knowledge in the management of halal certificates. The evaluation results in preparation, processing, presentation, and group creativity got a score of > 80, meaning that all groups practised well by the supervisor's guidance when the demonstration was carried out. Evaluation of the potential of Pebren juice, 84% categorised as good and evaluation of activities, 66% said it was beneficial, and 34% said it helped improve the family economy. Conclusion: Making pe bren juice without waste is beneficial for Aisyiyah Kowangan women to strengthen the family economy. Keywords: aisyiyah kowangan, skills, knowledge, pebren-extract without waste
Effect of Bekatewak Flour on Fasting Blood Glucose Levels (Study on Type 2 Diabetes Mellitus Rats Fed a High-Fat Diet) Bintanah, Sufiati; Rusyidie, Rijzal; Kurniati, Ika Dyah
Nutri-Sains: Jurnal Gizi, Pangan dan Aplikasinya Vol. 9 No. 1 (2025)
Publisher : Universitas Islam Negeri Walisongo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/ns.2025.9.1.20770

Abstract

High-fat diet (HFD) causes oxidative stress, which is a trigger for insulin resistance in type 2 diabetes mellitus. The provision of foods rich in antioxidants, such as rice bran, tempeh, and Javanese ginger, is needed to reduce oxidative stress. This study aimed to determine the effect of giving Bekatewak (a combination of rice bran, tempeh, and Javanese ginger) flour on fasting blood glucose levels of type 2 diabetes mellitus rats induced by HFD. This study was true experimental research using a pre- and post-test randomized controlled group design with a total of 18 rats as samples. There were three groups: the negative control group (K-), the positive control group (K+), and the treatment group (P). The study results showed a significant difference in fasting blood glucose levels before and after the administration of Bekatewak flour at a dose of 540 mg/200 g/bodyweight (p<0.05). There were significant differences in fasting blood glucose levels after intervention between K- and K+, K- and P, and K+ and P groups (p<0.001). Bekatewak flour has the potential to be developed as a functional food based on natural antioxidants to help control blood glucose levels and prevent insulin resistance caused by a high-fat diet.