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All Journal Medula JURNAL ILMIAH PETERNAKAN TERPADU JURNAL ILMIAH KESEHATAN SANDI HUSADA Jurnal Pengabdian Kepada Masyarakat (JPKM) Tabikpun AMMA : Jurnal Pengabdian Masyarakat Jurnal Ilmiah Kesehatan Sandi Husada
Hendri Busman
universitas lampung
Humanities Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Education Health Professions Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Journal : Medula

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Hububgan Hubungan Riwayat Merokok, Konsumsi Alkohol dan Diabetes dengan Derajat Histopatologi Karsinoma Kolorektal di RSUD Dr. H. Abdul Moeloek Bandar Lampung Periode 2017-2018 Gede Ardi Saputra; Rizki Hanriko; Hendri Busman; Muhartono
Medula Vol 10 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i4.154

Abstract

Colorectal carcinoma is a malignant neoplasm which originating or growing in the colon or rectum. Colorectal carcinoma is one of the 10 most common cancers suffered by Indonesians. Carcinomas develop much less in the duodenum, jejunum, and ileum than in the colon and rectum. The duodenum, jejunum, and ileum join the colon in the lower right abdomen. In the early stages most cancers do not show any particular clinical symptoms, however, early testing can minimize a poor prognosis. Screening or screening for colorectal carcinoma can be performed in groups of men and women over 50 years of age or patients who are at risk of developing colorectal carcinoma. Screening should also be done by people with polyps or individuals at risk of other carcinomas. The purpose of this study was to determine the frequen distribution and the relationship between smoking history, alcohol consumption history and diabetes history to the histopathological degree of colorectal carcinoma in RSUD Dr. H. Abdul Moeloek. This research was conducted in October-November 2019 at Dr. H. Abdul Moeloek Bandar Lampung using the observational method. The sample of this study consisted of 94 people with medical record data determined using total sampling techniques. Data were processed using statistical tests with a confidence level of 0.05. Chi-square test results showed that there is a  correlation between smoking history (p = 0.0008), alcohol consumption (p = 0.006) and diabetes mellitus (p = 0.015) with the histopathological degree of colorectal carcinoma. So, it can be concluded there is a correlation between smoking history, alcohol consumption and diabetes.
PENGARUH EKTRAK KULIT MANGIS (Gracinia mangostan L.) TERHADAP JUMLAH RERATA SPERMATOSIT PRIMER TIKUS PUTIH JANTAN (Rattus Novergicus) Galur Spragua dawley YANG DIINDUKSI PLUMBUM ASETAT I gede sugiana Karaeng; anggraini janar wulan; Hendri Busman
Medula Vol 11 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v11i4.302

Abstract

The Pb metal content in motor vehicle exhaust gases can danger health and  damage the environment. Pb metal as a free radical can trigger oxidative stress. Oxidative stress causes an increase in reactive oxygen species (ROS) and damage to the spermatozoa membrane. Antioxidants are one of the compounds that can be used to overcome this problem, including the mangosteen peel extract which has a view of antioxidants as an antidote to free radicals. This experimental was conducted for 14 days. 25 male rats (Spragua dawley) were divided into 5 treatment groups: K + (without treatment), K-, P1, P2, P3 (exposed to plumbum acetate dose of 0.35gram / KgBB and given consecutively mangosteen peel extract at a dose of 0 , 50, 100, 200 mg / KgBB, mean primary sprematocytes were calculated using a microscope with 400x magnification. The results of the treatment analysis (P1, P2, and P3) showed that the mangosteen peel extract had not been able to increase mean primary spematocytes from male white rats, mean that of primary spermatocytes obtained was 133.2 ± 24 (K+), 71.85 ± 16.9 (K-), 72.0 ± 17.3 (P1), 29.2 ± 9.3 (P2), 43.3 ± 6.82 (P3)test post hoc LSD showed significant differences from each treatment group. The extract of the Mangosteen skin was not yet able to increase Average of primary spermatocytes of male white rats exposed to plumbum acetate.
Co-Authors Agung Abadi Kiswandono Andestya Nanda Pratama anggraini janar wulan Arie Khoiriyah Bambang Irawan C. N. Ekowati Emantis Rosa Endang Nurcahyani Gede Ardi Saputra I gede sugiana Karaeng Muhartono Nuning Nurcahyani Nur Lailatul Arofah Ostarica Alqoriani A. Primasari Pertiwi Qotrunnada Salsabila Rizki Hanriko Salman Farisi Sumardi, Sumardi Suratman Suratman Suratman Susanto, Gregorius Nugroho Sutyarso Yulianti Yulianti Yulianty Soeradji