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Potensi Antioksidan Kedelai (Glycine Max L) Terhadap Penangkapan Radikal Bebas Andestya Nanda Pratama; Hendri Busman
Jurnal Ilmiah Kesehatan Sandi Husada Vol 9 No 1 (2020): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v11i1.333

Abstract

Free radicals are molecules that have unstable and reactive properties, because they have one or more unpaired electrons. Free radicals can attack vulnerable compounds such as lipids and proteins, which will eventually cause dangerous diseases. Free radicals threaten the health of the body because of their reactive and unstable nature, because of their instability, free radicals react with molecules that are closest after entering the body, and produce other free radicals, and eventually become a chain reaction that can threaten the health of the body. Soybean (Glycine max L) has antioxidant compounds that can react with free radicals and stop the rate of free radicals to react with molecules in the body, namely isoflavones and other compounds, such as proteins, fats, and vitain A, C and D. Soybean (Glycine max L) has been shown to play an important role in healing or inhibiting diseases caused by free radicals, as well as the antioxidants contained, namely isoflavones that are consumed regularly can protect the body from free radicals
Aktivitas Anti-Inflamasi Bawang Hitam (Allium sativum L.) Qotrunnada Salsabila; Hendri Busman
Jurnal Ilmiah Kesehatan Sandi Husada Vol 10 No 1 (2021): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v10i1.502

Abstract

Introduction: Inflammation is a series of non-specific innate processes that are activated by the body in response to foreign invasion, tissue damage, or both. Purpose: To determine the anti-inflammatory activity of black onions. Methods: using literature studies from national and international journals by summarizing discussion topics and comparing the results in articles. Results: Black onions have anti-inflammatory activity through their bioactive components S-allyl cysteine, polyphenols, and flavonoids and can be used as an alternative anti-inflammatory agent in phytopharmaca. Conclusion; The fermentation process carried out by heat treatment at certain humidity in garlic will produce an end product in the form of black garlic or aged black garlic
Efek Protektif Ekstrak Daun Jambu Air (Syzygium Aqueum) terhadap Kerusakan Lambung Tikus Putih Jantan (Rattus Norvegicus) Galur Wistar yang Diinduksi Indometasin Adilla Justisia; Susianti Susianti; Anisa Nuraisa Jausal; Hendri Busman
Malahayati Nursing Journal Vol 7, No 8 (2025): Volume 7 Nomor 8 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i8.21126

Abstract

ABSTRACT The prevalence of peptic ulcers caused by the use of Nonsteroidal Anti-Inflammatory Drugs (NSAID) has increased over the past 10 years. Oxidative stress induced by NSAID can trigger the formation of peptic ulcers. The objective of this research was to determine the protective effect of water apple leaf extract (Syzygium aqueum) on gastric damage of male white rats (Rattus norvegicus) wistar strain induced by indomethacin. This laboratory experimental study with a randomized post-test only control group design involved 24 male Wistar strain white rats divided into 6 groups. Group K(0) was given food and water, K(-) was administered indomethacin at a dose of 30 mg/kgBW, K(+) received vitamin C at a dose of 9 mg/kgBW and indomethacin at 30 mg/kgBW, while P1, P2, and P3 were given water apple leaf extract at doses of 100 mg/kgBW, 300 mg/kgBW, and 900 mg/kgBW, along with indomethacin at 30 mg/kgBW. The results of the Mann-Whitney statistical test analysis showed a significant difference (p0.05) between group K(-), which was administered only indomethacin, and group P2 and P3, which were administered extracts of water apple leaf at doses of 300 mg/kgBW and 900 mg/kgBW along with indomethacin at 30 mg/kgBW. There is an protective effect of water apple leaf extract (Syzygium aqueum) on gastric damage of male white rats (Rattus norvegicus) Wistar strain induced by indomethacin. Keywords: Water Apple Leaf, Syzygium Aqueum, Antioxidants, Indomethacin, Peptic Ulcer  ABSTRAK Prevalensi ulkus peptikum yang disebabkan oleh penggunaan Nonsteroidal Anti-Inflammatory Drugs (NSAID) mengalami peningkatan dalam kurun waktu 10 tahun. Stres oksidatif yang disebabkan oleh NSAID dapat memicu terbentuknya ulkus peptikum. Tujuan penelitian ini untuk mengetahui efek protektif ekstrak daun jambu air (Syzygium aqueum) terhadap kerusakan lambung tikus putih jantan (Rattus norvegicus) galur wistar yang diinduksi indometasin. Penelitian eksperimental laboratorik dengan rancangan randomized post-test only control group ini menggunakan 24 tikus putih jantan galur Wistar yang dibagi ke dalam 6 kelompok. K(0) diberikan makan dan minum, K(-) diberikan indometasin 30 mg/kgBB, K(+) diberikan vitamin C 9 mg/kgBB dan indometasin 30 mg/kgBB, serta P1, P2, P3 diberikan ekstrak daun jambu air dengan dosis berturut-turut 100 mg/kgBB, 300 mg/kgBB, 900 mg/kgBB dan indometasin 30 mg/kgBB. Hasil analisis uji statistik Mann-Whitney didapatkan perbedaan bermakna (p0.05) antara kelompok K(-) yang hanya diberikan indometasin dengan kelompok P2 dan P3 yang diberikan ekstrak 300 mg/kgBB dan 900 mg/kgBB serta indometasin 30 mg/kgBB. Ekstrak daun jambu air (Syzygium aqueum) memberikan efek protektif terhadap kerusakan lambung tikus putih (Rattus norvegicus) jantan galur Wistar yang diinduksi indometasin. Kata Kunci: Daun Jambu Air, Syzygium aqueum, Antioksidan, Indometasin, Ulkus Peptikum
Eksaserbasi Sedang PPOK Grup E TB Paru, Baru Terdiagnosis Klinis pada Bulan Pertama Perawatan Fase Intensif, HIV Negatif Syazili Mustofa; Aisyah Ramadhani; Giska Tri Putri; Hendri Busman; Jordy Oktobiannobel
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 12 No 3 (2026): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol. 12.3 (2026)
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v12i3.1018

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory disorder frequently associated with pulmonary tuberculosis (TB), particularly in individuals with risk factors such as smoking. We report a 65-year-old male with COPD group E who presented with dyspnea and chronic productive cough. The patient was diagnosed with newly detected pulmonary TB and was undergoing the intensive phase of anti-tuberculosis drug (OAT) therapy. Physical examination revealed bilateral wheezing with an oxygen saturation of 90%, which increased to 93% after administration of 2 L/min of supplemental oxygen; cardiac function was within normal limits. The patient received inhaled bronchodilators, intravenous methylprednisolone, levofloxacin, and OAT. After 10 days of hospitalization, dyspnea improved along with an increase in daily peak expiratory flow (PEF) values. This case highlights the importance of a multidisciplinary approach involving infection control and pharmacotherapy adjustment to achieve optimal clinical improvement in COPD patients with coexisting tuberculosis.  
Penggunaan Aerated Compost Tea Dari Bahan Kompos Seresah Untuk Nutrisi Dan Perlindungan Tanaman Salman Farisi; Bambang Irawan; Suratman; Hendri Busman
AMMA : Jurnal Pengabdian Masyarakat Vol. 3 No. 7 : Agustus (2024): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

One product of composting technology that also growing rapidly is the manufacture of compost tea (CT). CT is an oxygenated compost water extract obtained through aeration in the liquid phase. The process of making CT with this method is called Aerated Compost Tea (ACT). ACT is a compost water extract containing dissolved nutrients and growth hormones. In addition to functioning as a source of nutrients, ACT can also improve the soil ecosystem for the growth of decomposing microbes that can support soil fertility, improve soil physical and biological properties, improve microbial activity, and can also increase plant resistance to pathogens. ACT provides dissolved nutrients that are more quickly absorbed by plants and at the same time provides biopesticides to prevent or inhibit infection by pathogens that cause plant diseases. This Community Service activity is the development of science and technology from the results of research that has been carried out. The results of Community Service show quite good results, namely there is an increase of about 33.35% from the initial understanding. This is quite interesting because the initial understanding of ACT was low, at level of 60.54. The explanation given by the Community Service team, able to be understood by the target audience well so that their understanding increased to 78.02.
Pengenalan Dan Penggunaan Edible Coating Dalam Meningkatkan Mutu Buah Dan Sayuran Bagi KWT Anggrek Kecamatan Merbau Mataram Kabupaten Lampung Selatan Endang Nurcahyani; Yulianty; Emantis Rosa; Hendri Busman
AMMA : Jurnal Pengabdian Masyarakat Vol. 3 No. 9 : Oktober (2024): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Fruits and vegetables are horticultural products. This product is easily damaged, so it needs good handling and sufficient attention. So that damage arising from poor handling can be reduced and avoided. Fast handling, sometimes by using materials that are not safe for humans, such as wax. Problems in handling fruits and vegetables occur not only in villages but also in urban areas. So it is necessary to understand and practice for women members of KWT Anggrek  in Merbau Mataram District, South Lampung Regency about the use of natural Edible Coatings that are safe for health. The use of Edible Coating is not just giving a thin layer on fruits and vegetables, but it is necessary to find the use of Edible Coating that does not make problems when eaten and of course is environmentally friendly, such as aloe vera, cassava, taro and sweet potato. The pre-test results of the Community Service Participants were 83.2. The post-test results showed an increase with a score of 96.8. This result proves that there is an increase in the understanding and skills of Community Service participants. The existence of this service is expected that KWT Anggrek  members can handle fruits and vegetables that are easily damaged and rotten so that they can last longer, namely by using Edible Coating Natural  that are easily obtained in the surrounding environment and are environmentally friendly.  
Pemberdayaan Kreativitas Petani Aren Melalui Pelatihan Pembuatan Nata de Legen Di Desa Sidokaton, Kecamatan Gisting, Kabupaten Tanggamus, Lampung Endang Nurcahyani; Hendri Busman; Yulianty
AMMA : Jurnal Pengabdian Masyarakat Vol. 4 No. 11 : Desember (2025): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Communities have long recognized the sugar palm (Arenga pinnata Merr.) as a plant that produces various economically valuable products, particularly for the craft and food industries; however, its development and cultivation have received relatively little attention. In Sidokaton Village, Gisting District, Tanggamus Regency, the sugar palm is one of the leading local commodities widely cultivated by farmers. Most farmers process sugar palm into palm sugar and kolang-kaling, while the sap is commonly used only as a fresh beverage with a low selling price that fluctuates significantly during the harvest season. This condition highlights the need for innovations in utilizing sugar palm sap to increase its added value for farmers. This community service activity introduces an innovation in processing sugar palm sap into Nata de Legen as an alternative to nata de coco. This innovation aims to enhance the community’s knowledge and skills regarding product diversification of sugar palm and to encourage increased income through higher-value processed products. There was an increase in public knowledge about processing and utilizing palm sap to produce the economically valuable nata de legen. The average increase in knowledge among training participants was 17.33 points. The training activities are expected to serve as an initial step in the development of sustainable local resource–based enterprises in Sidokaton Village.
Optimalisasi Pemanfaatan Buah Belimbing Wuluh (Averrhoa bilimbi L.) Bagi Ibu-Ibu PKK RT 004 Kelurahan Labuhan Ratu Bandar Lampung Yulianty; Endang Nurcahyani; Bambang Irawan; Emantis Rosa; Hendri Busman; Salman Farisi; Suratman Umar
AMMA : Jurnal Pengabdian Masyarakat Vol. 5 No. 1 : Februari (2026): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Averrhoa bilimbi L. is a type of plant that grows in yards or home gardens. This species belongs to the order Oxalidales and the family Oxalidaceae. This species belongs to the Oxalidales order and Oxalidaceae family. This plant has many benefits, including its stems, leaves, flowers, and fruit. The women of PKK RT 004 generally use the fresh flowers and fruit. The fresh fruit is used as an addition in making fish pindang as a substitute for tamarind and candis acid. However, the women of PKK have never used preserved fruit as sweets and asam sunti.  Therefore, it is necessary to optimize the use of fruit  by preserving it, such asam sunti.  Asam sunti is commonly used by the people of Aceh. Asam sunti is made from dried fruit, which is salted and dried in the sun repeatedly until the  fruit is dry and brown in color. The results of this community service activity showed good pre-test and post-test scores. The average pre-test score was 92.87 and the average post-test score was 98. There was an increase of 5.33 points. The sustainability of this community service activity is that the PKK mothers of RT 004 can disseminate the information obtained from this activity to other communities.
EFEKTIVITAS DAN KARAKTERISASI FISIK LOSION EKSTRAK ETIL ASETAT DAUN ZODIA (Evodia suaveolens) SEBAGAI REPELAN TERHADAP NYAMUK Aedes aegypti Aqila Nisa; Emantis Rosa; Sutyarso; Hendri Busman
Jurnal Manajemen, Ekonomi, Hukum, Kewirausahaan, Kesehatan, Pendidikan dan Informatika Vol 4 No 3 (2026): Jurnal Manajemen, Ekonomi, Hukum, Kewirausahaan, Kesehatan, Pendidikan dan Inform
Publisher : Shofanah Media Berkah

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Abstract

Dengue Hemorrhagic Fever (DHF) has shown an increase in cases and deaths in recent years, reaching 14.6 million cases in 2024 and causing 12,000 deaths. So far, people rely on synthetic repellents containing DEET (N, N-diethyl-meta-toluamide) for prevention. However, long-term use can cause side effects. Therefore, the development of plant-based repellents is needed, such as zodia leaves (E. suaveolens). This study aims to determine the percentage of protective power, determine the EC50 value, and determine the physical properties of ethyl acetate extract lotion from zodia leaves (Evodia suaveolens) through organoleptic, homogeneity, and irritation tests. This study is experimental and descriptive using a Completely Randomized Design (CRD) consisting of 4 test concentrations, namely 0%, 5%, 10%, and 15%. The data obtained were analyzed using one-way ANOVA, followed by LSD test, and probit analysis. The physical properties of ethyl acetate lotion from zodia leaves (Evodia suaveolens) were analyzed descriptively and visually. The results showed that the increase in concentration was directly proportional to the protective power. The mosquito repellent power at concentrations of 5% (18.85%), 10% (33.53%), and 15% (53.27%). The 15% concentration was the highest protective power. Based on probit analysis, the EC50 value was 14.56%. Based on the physical properties of the lotion, it showed that the lotion was homogeneous, had good characteristics, and did not cause irritation.
Uji Biolarvasida Ekstrak Metanol Daun Pepaya Jepang pada Larva Anopheles sp. Dea Farrah Khairunnisa; Emantis Rosa; Priyambodo; Hendri Busman
OKTAL : Jurnal Ilmu Komputer dan Sains Vol 5 No 05 (2026): OKTAL : Jurnal Ilmu Komputer Dan Sains
Publisher : CV. Multi Kreasi Media

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Abstract

Malaria remains a major health problem in endemic areas such as Pesawaran Regency, Lampung, transmitted through the bites of infected female Anopheles mosquitoes. Continuous use of synthetic larvicides may lead to resistance, toxicity to non-target organisms, and environmental pollution, thus safer biolarvicidal alternatives are needed. Japanese papaya leaves (Cnidoscolus aconitifolius) are known to contain secondary metabolites with potential biolarvicidal activity. This study aimed to determine the biolarvicidal activity of methanol extract of Japanese papaya leaves against the mortality of Anopheles larvae and to observe morphological changes in larvae after exposure. The study used a Completely Randomized Design with five treatments: 0% (control), 0.5%, 1%, 1.5%, and 2%, each with five replications. Data were analyzed using one-way ANOVA followed by the Least Significant Difference (LSD) test. Phytochemical screening revealed the presence of alkaloids, flavonoids, saponins, tannins, phenols, and steroids. ANOVA results showed significant differences among treatments (p<0.001), while the LSD test indicated that each concentration had a significantly different effect on larval mortality (p<0.05). The highest mortality was observed at 2% concentration, reaching 82.5% at 24 hours and 100% at 48 hours. The methanol extract also caused morphological damage in larvae, including tissue lysis, digestive tract damage, and respiratory system impairment. It can be concluded that the methanol extract of japanese papaya leaves has potential as a natural biolarvicide against Anopheles larvae.