Article Per Year (5 Year)
p-Index From 2021 - 2026
4.055
P-Index
This Author published in this journals
All Journal Pharmaciana: Jurnal Kefarmasian Naturalis : Jurnal Penelitian Pengelolaan Sumberdaya Alam dan Lingkungan PENA SAINS Jurnal Kimia Riset Journal of Health (JoH) JPM (Jurnal Pemberdayaan Masyarakat) JCES (Journal of Character Education Society) EMBRIO : Jurnal Kebidanan Jurnal Surya Masyarakat JAST : Jurnal Aplikasi Sains dan Teknologi LOYALITAS: Jurnal Pengabdian Kepada Masyarakat Health Information : Jurnal Penelitian Medicra (Journal of Medical Laboratory Science/Technology) Madaniya Jurnal Surya Masyarakat Jurnal Pengabdian Masyarakat dalam Kesehatan Medical Scope Journal (MSJ) Jurnal Abdimas Kartika Wijayakusuma Proceedings of The ICECRS Procedia of Social Sciences and Humanities Indonesian Journal of Community Diversity and Engagement International Journal Multidisciplinary Indonesian Journal Health Science and Medicine Academia Open
Jamilatur Rohmah
Universitas Muhammadiyah Sidoarjo
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

Published : 42 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 42 Documents
Search

 1   2   3   4   5 
Toxicity Testing of Turi Putih Bark Extract on Mice Liver: Pengujian Toksisitas Ekstrak Kulit Batang Turi Putih pada Hati Mencit Mujemilatul Hasanah; Jamilatur Rohmah
Academia Open Vol. 8 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.8.2023.5429

Abstract

General background the use of natural extracts in assessing toxicity has gained attention due to the growing interest in alternative medicine and natural products. Specific background Sesbania grandiflora, commonly known as turi putih, is a plant with potential medicinal properties, but its safety profile regarding hepatic toxicity remains inadequately explored. Knowledge gap while previous studies have examined various plants for their pharmacological effects, research specifically focusing on the hepatotoxicity of turi putih extract is lacking. Aims this study aims to evaluate the toxicity of ethanol extract from the bark of Sesbania grandiflora on liver function, as measured by SGOT and SGPT levels, in Mus musculus. Results showed no mortality or toxic symptoms in the mice exposed to the extract. Macroscopic examination of the liver indicated normal color, consistency, and shape. Statistical analysis yielded p-values of 0.502 for liver weight, 0.226 for SGOT, and 0.366 for SGPT, indicating no significant effects from the treatment. Novelty this research contributes new insights into the safety profile of Sesbania grandiflora, demonstrating its non-toxic effects at the tested doses. Implications the findings suggest that the bark extract of turi putih may be safe for use, highlighting its potential in herbal medicine without adverse hepatic effects. Highlights: No observed toxicity or mortality in mice after exposure to the extract. Normal liver function indicated by SGOT and SGPT levels. Potential safety of turi putih bark extract for medicinal use. Keywords: Turi Putih, Hepatotoxicity, Sesbania grandiflora, Mice, Ethanol Extract
Toxicity of White Turi Stem Bark Extract on Mice: Toksisitas Ekstrak Kulit Batang Turi Putih pada Mencit Anisatus Shalihah Amalia; Jamilatur Rohmah
Academia Open Vol. 8 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.8.2023.5432

Abstract

General background the use of traditional medicinal plants has gained attention due to their potential therapeutic benefits and safety. Specific background among these, Sesbania grandiflora (L.) Pers., commonly known as white turi, is recognized for its various bioactive compounds. However, there is a knowledge gap regarding the toxicity of its stem bark extract, particularly concerning its effects on vital organs such as the kidneys. Aims this study aims to evaluate the toxicity of white turi stem bark extract on mice by determining the LD50 and assessing kidney health through biochemical parameters such as Blood Urea Nitrogen (BUN) and creatinine levels.The results indicate no significant toxic symptoms or mortality in the treated mice, with macroscopic kidney observations showing reddish-brown coloration and a consistent texture resembling red kidney beans.Novelty this study provides novel insights into the safety profile of Sesbania grandiflora stem bark extract, suggesting that it does not pose significant renal toxicity. Implications these findings support its traditional use while encouraging further research into its pharmacological properties. Highlights: No significant toxic symptoms observed in treated mice. Macroscopic kidney analysis indicated no severe damage. Statistical results confirmed no renal toxicity at various extract doses. Keywords: Sesbania Grandiflora, Toxicity, LD50, Kidneys, Mice
Co-Authors Achmad Noerkhaerin Putra Aini, Latifatul Andika Aliviameita Anisatus Shalihah Amalia Anwar, Najih Arini Siti Wahyuningsih Aziza, Vidayatul Chylen Setiyo Rini Devi Arvindani Masyitha Eni Fariyatul Fahyuni Fadilah, Fitrian Nur FATMAWATI, RIRIN Firdaus, Firyalita Sarah Fitria Ayu Prayekti, Rahmatika Fitria Eka Wulandari Fitrian Desi Prameswari Fiya, Uus Ufita Furqonati, Lili Galuh Ratmana Hanum Handini, Hesti Dwi Hidayat, Mokhamad Amirul Ida Agustini Saidi Karlia Hedit Tiana Khusniyah, Nurul Liyaajul, Pratasyah Makrufah, Makrufah Margareta, Frida Amelia Marlina, Mariany Lambertine Martina, Shofie Fitria Miftahul Mushlih Miranda, Niken Anggita Mujemilatul Hasanah Mukarromah, Rizka Aisya Novitasari, Fia NUR EFENDI Nurul Azizah NURUL AZIZAH Paramitha Amelia Kusumawardani Purwanti, Yanik Purwanti Puspitasari Puspitasari Puspitasari Puspitasari Putra, Moh. Faris Yudiana Rafhani Rosyidah Rini , Chylen Setiyo Rini, Chylen S. Rofidah, Luthfiyah Salsabila Widya Kirana Setiyo Rini, Chylen Siroj, Muhammad Said Agil Siti Cholifah SITI CHOLIFAH Sofi Rahayu, Bella Tri Chahyani Rahmawati Putri Tri Linggo Wati Vanda Rezania Wakhidah, Kemil Widyaningrum, Leni Yuroh Yuli Astutik Zulfida Ainindiyah Putri Purwanto Zurrotul Ilmiyah