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All Journal Pharmaciana: Jurnal Kefarmasian Naturalis : Jurnal Penelitian Pengelolaan Sumberdaya Alam dan Lingkungan PENA SAINS Jurnal Kimia Riset Jurnal Ilmiah Kedokteran Wijaya Kusuma JPM (Jurnal Pemberdayaan Masyarakat) JCES (Journal of Character Education Society) EMBRIO : Jurnal Kebidanan Jurnal Surya Masyarakat JAST : Jurnal Aplikasi Sains dan Teknologi Health Information : Jurnal Penelitian Jurnal Ners Medicra (Journal of Medical Laboratory Science/Technology) Madaniya Jurnal Surya Masyarakat Jurnal Pengabdian Masyarakat dalam Kesehatan Medical Scope Journal (MSJ) Jurnal Abdimas Kartika Wijayakusuma Proceedings of The ICECRS Procedia of Social Sciences and Humanities Indonesian Journal of Community Diversity and Engagement Journal of Pharmaceutical and Sciences. International Journal Multidisciplinary Indonesian Journal Health Science and Medicine Academia Open LOYALITAS: Jurnal Pengabdian Kepada Masyarakat
Jamilatur Rohmah
Prodi Teknologi Laboratorium Medis, Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Sidoarjo
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Toxicity of White Turi Stem Bark Extract on Mice: Toksisitas Ekstrak Kulit Batang Turi Putih pada Mencit Anisatus Shalihah Amalia; Jamilatur Rohmah
Academia Open Vol. 8 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.8.2023.5432

Abstract

General background the use of traditional medicinal plants has gained attention due to their potential therapeutic benefits and safety. Specific background among these, Sesbania grandiflora (L.) Pers., commonly known as white turi, is recognized for its various bioactive compounds. However, there is a knowledge gap regarding the toxicity of its stem bark extract, particularly concerning its effects on vital organs such as the kidneys. Aims this study aims to evaluate the toxicity of white turi stem bark extract on mice by determining the LD50 and assessing kidney health through biochemical parameters such as Blood Urea Nitrogen (BUN) and creatinine levels.The results indicate no significant toxic symptoms or mortality in the treated mice, with macroscopic kidney observations showing reddish-brown coloration and a consistent texture resembling red kidney beans.Novelty this study provides novel insights into the safety profile of Sesbania grandiflora stem bark extract, suggesting that it does not pose significant renal toxicity. Implications these findings support its traditional use while encouraging further research into its pharmacological properties. Highlights: No significant toxic symptoms observed in treated mice. Macroscopic kidney analysis indicated no severe damage. Statistical results confirmed no renal toxicity at various extract doses. Keywords: Sesbania Grandiflora, Toxicity, LD50, Kidneys, Mice
High Dose Sesbania Grandiflora Extract Alters Rat Kidney Electrolytes based on Insights from Indonesia: Ekstrak Sesbania Grandiflora Dosis Tinggi Mengubah Elektrolit Ginjal Tikus berdasarkan Wawasan dari Indonesia Mokhamad Amirul Hidayat; Jamilatur Rohmah
Academia Open Vol. 9 No. 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.7812

Abstract

This study investigates the acute toxicity of white turi flower extract (Sesbania grandiflora) on kidney electrolyte levels in rats (Rattus norvegicus). Conducted at Muhammadiyah University of Sidoarjo, male Wistar rats were divided into control and treatment groups, receiving 10,000, 15,000, and 20,000 mg/kgBW doses. Symptoms of toxicity included lethargy and hair loss, but no deaths occurred. Despite normal macroscopic kidney observations, sodium and potassium levels significantly increased with higher doses (p=0.000). These findings suggest that high doses of white turi flower extract can affect kidney electrolytes, indicating potential toxicity. Further research is needed to assess long-term safety for medicinal use. Highlights: 1. High doses increase sodium and potassium in rat kidneys.2. Symptoms: lethargy, hair loss, no fatalities.3. Requires further research for long-term safety. Keywords: Sesbania grandiflora, acute toxicity, kidney electrolytes, sodium, potassium
Sesbania grandiflora Extract Reduces ALP and GGT in Paracetamol Toxicity: Ekstrak Sesbania grandiflora Mengurangi ALP dan GGT pada Toksisitas Parasetamol Veronika Oktaruliawan; Jamilatur Rohmah
Academia Open Vol. 10 No. 2 (2025): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.10.2025.12413

Abstract

General Background: Oxidative stress generated by excessive free radicals contributes to hepatic injury, particularly during metabolism of hepatotoxic drugs. Specific Background: Paracetamol overdose produces the reactive metabolite N-acetyl-p-benzoquinone imine, which triggers lipid peroxidation and elevates liver enzymes such as Alkaline Phosphatase (ALP) and γ-Glutamyl Transferase (GGT). Sesbania grandiflora leaves contain bioactive compounds including flavonoids, alkaloids, and tannins with antioxidant properties. Knowledge Gap: Scientific evidence describing the biochemical response of ALP and GGT to Sesbania grandiflora leaf extract under paracetamol-induced hepatotoxic conditions remains limited. Aims: This study evaluated the biochemical changes in ALP and GGT levels and oxidative stress marker malondialdehyde (MDA) in male Wistar rats administered toxic paracetamol doses followed by graded Sesbania grandiflora leaf extract treatment. Results: Experimental randomized controlled laboratory research involving 28 rats demonstrated significant differences in MDA, ALP, and GGT values across treatment groups (p<0.05). Paracetamol administration elevated oxidative stress and liver enzyme parameters, while extract administration decreased MDA and reduced ALP and GGT levels. The 1000 mg/kg body weight dose produced enzyme values approaching physiological ranges. Novelty: This study presents combined biochemical evaluation of oxidative stress indicators and dual liver enzyme parameters following graded Sesbania grandiflora leaf extract administration in paracetamol-induced hepatic injury. Implications: Sesbania grandiflora leaf extract represents a potential natural hepatoprotective candidate with antioxidant activity relevant for managing drug-induced liver injury and supporting development of plant-based therapeutic agents. Highlights: Highest Administered Dose Returned Enzyme Biomarkers Close to Physiological Values. Antioxidant Administration Lowered Lipid Peroxidation Indicator Concentrations in Treated Animals. Statistical Analysis Confirmed Significant Biochemical Differences Between Intervention and Control Groups. Keywords: Sesbania Grandiflora; Hepatoprotection; Oxidative Stress; Alp; Gamma Glutamyl Transferase
Pelatihan Higiene dan Sanitasi Makanan pada Pedagang Makanan di Kantin Sekolah Dasar Jamilatur Rohmah; Siti Cholifah; Vanda Rezania
Jurnal Pemberdayaan Masyarakat Vol 4 No 1 (2019): Mei
Publisher : Direktorat Penelitian dan Pengabdian kepada Masyarakat (DPPM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (296.788 KB) | DOI: 10.21067/jpm.v4i1.3241

Abstract

The school canteen has an important role to fulfill the food needs of school children. The need for fulfillment of hygienic foods is ordered by the factors of place and hygiene of the food handlers. Foods that do not meet the requirements and safety that can be given due to health problems or diseases related to food such as diarrhea, cholera, dysentery, typhus, and other food poisoning. The number of food handlers in the cafeteria of SD Muhammadiyah 1 and 2 Sidoarjo competes 6 people. Based on the results of observations and interviews, they did not have sufficient educational background and never gained knowledge about food hygiene and sanitation. The purpose of this PPM activity are to improve the knowledge, attitudes, and behavior of food handlers about food hygiene and sanitation so not to harm their consumers health, especially school children. The method used is a training and mentoring model for food handlers starting when preparing food, processing, and serving to customers. The results of these program can be known about changes in the knowledge and skills of food handlers in food hygiene and sanitation.
Pelatihan Higiene dan Sanitasi Makanan pada Pedagang Makanan di Kantin SD Jamilatur Rohmah; Siti Cholifah; Vanda Rezania
LOYALITAS: Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 2 (2019): November 2019
Publisher : Universitas KH. Mukhtar Syafaat (UIMSYA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30739/loyal.v2i2.473

Abstract

The school canteen has an important role to fulfill the food needs of school children. In general, foods that are sold in canteens have very diverse variations, with prices relatively cheap and easily accessible to school children. The need for fulfillment of hygienic foods is ordered by the factors of place and hygiene of the food handlers need to be done. Foods that do not meet the requirements and safety that can be given due to health problems or diseases related to food such as diarrhea, cholera, dysentery, typhus, and other food poisoning. The number of food handlers in the cafeteria of SD Muhammadiyah 1 and 2 Sidoarjo competes 6 people. Based on the results of observations and interviews, they did not have sufficient educational background in terms of hygiene and food sanitation, and they never gained knowledge about food hygiene and sanitation. This will greatly determine the quality of food provided to consumers especially elementary school children. Based on this, the Community Service activities on hygiene training and food sanitation were carried out at food handlers in the cafeteria of Muhammadiyah 1 and 2 elementary schools in Sidoarjo.
Analysis of Differences in Triglyceride Levels between Tobacco Smokers and Electric Smokers in Students (Ormawa) of Muhammadiyah University of Sidoarjo: Analisa Perbedaan Kadar Trigliserida antara Perokok Tembakau dan Perokok Elektrik pada Mahasiswa (Ormawa) Universitas Muhammadiyah Sidoarjo Mukarromah, Rizka Aisya; Hanum, Galuh Ratmana; Rohmah, Jamilatur; Rini , Chylen Setiyo
Indonesian Journal on Health Science and Medicine Vol. 3 No. 3 (2026): Desember
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v3i3.549

Abstract

General Background: Electronic medical records (EMR) require standardized data variables to support compatibility and interoperability within healthcare information systems. Specific Background: Bhayangkara Porong Hospital uses the Enterprise Hospital System (E-HOS) for electronic medical record management, but the completeness of its variables needs to correspond with the variables established by the Ministry of Health. Knowledge Gap: The extent to which EMR variables in the E-HOS application comply with the specified regulatory guidelines required systematic assessment. Aims: This study aimed to identify and analyze incomplete EMR variables in the E-HOS application at Bhayangkara Porong Hospital. Results: This qualitative descriptive study collected data through observation, interviews, and documentation studies concerning regulations governing electronic system variables and metadata. The findings showed that 10 EMR variables did not comply with the applicable guidelines, while 9 variables complied. The compliance levels varied across patient identification, payment methods, general consent, initial assessment, and specialist examination forms. Notably, the general consent variables showed 0% compliance, while several initial assessment variables reached 100% compliance. Novelty: The study examines the compliance of E-HOS variables with the Ministry of Health guidelines across multiple outpatient EMR components at Bhayangkara Porong Hospital. Implications: The findings identify specific variables requiring attention in the implementation of EMR and provide a basis for aligning the E-HOS application with established regulatory requirements. Key Findings Ten electronic medical record variables were identified as non-compliant with the applicable guidelines. Nine variables were found to comply with the established requirements. Initial assessment variables achieved full compliance, whereas general consent variables showed no compliance. Keywords : Electronic Medical Records, E-HOS, Data Variables, Regulatory Compliance, Hospital Information System
Perbandingan Aktivitas Antibakteri Ekstrak Tempoyak Terhadap Pertumbuhan Escherichia Coli dan Bacillus Cereus Chylen Setiyo Rini; Jamilatur Rohmah; Novita Arisanti
Jurnal Ners Vol. 10 No. 4 (2026)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i4.63390

Abstract

Keracunan makanan yang disebabkan oleh bakteri patogen seperti Escherichia coli dan Bacillus cereus tetap menjadi masalah kesehatan masyrakat. Tempoyak, produk durian yang difermentasi, berpotensi berfungsi sebagai agen antibakteri alami karena mengandung berbagai metabolit sekunder. Penelitian ini bertujuan menganilisis aktivitas antibakteri ekstrak tempoyak terhadap E.coli dan B.cereus. Penelitian ini menggunakan metode eksperimental laboratorium. Ekstrak tempoyak diperoleh melalui proses maserasi menggunakan etanol 96% (3L) selama 3 x 24 jam, kemudian diuji menggunakan metode difusi cakram (Kirby-Bauer) pada konsentrasi 25%, 50%, 75%, dan 100%, dengan 250 gram kloramfenikol sebagai kontrol positif dan air suling sebagai kontrol negatif. Skrining fitokimia menjukkan adanya alkaloid, saponin, steroid, triterpenoid, fenolik, dan tanin, dengan alkaloid menjukkan intensitas reaksi kualitatif terkuat. Hasil uji ANOVA dua arah menjukkan bahwa konsentrasi ekstrak, spesies bakteri, dan interaksinya memiliki pengaruh yang signifikan terhadap diameter zona penghambat (p < 0,05).
Co-Authors Achmad Noerkhaerin Putra Aini, Latifatul Andika Aliviameita Anisatus Shalihah Amalia Anwar, Najih Arini Siti Wahyuningsih Aziza, Vidayatul Chylen Setiyo Rini Devi Arvindani Masyitha Eni Fariyatul Fahyuni Fadilah, Fitrian Nur FATMAWATI, RIRIN Fikih Putri Ayu Nabila Firdaus, Firyalita Sarah Fitria Ayu Prayekti, Rahmatika Fitria Eka Wulandari Fiya, Uus Ufita Furqonati, Lili Galuh Ratmana Hanum Handini, Hesti Dwi Hidayat, Mokhamad Amirul Ida Agustini Saidi Karlia Hedit Tiana Khusniyah, Nurul Liyaajul, Pratasyah Makrufah, Makrufah Margareta, Frida Amelia Marlina, Mariany Lambertine Martina, Shofie Fitria Miftahul Mushlih Miranda, Niken Anggita Mokhamad Amirul Hidayat Mujemilatul Hasanah Mukarromah, Rizka Aisya Novita Arisanti Novitasari, Fia NUR EFENDI Nurul Azizah Paramitha Amelia Kusumawardani Purwanti, Yanik Puspitasari Puspitasari Puspitasari Puspitasari Putra, Moh. Faris Yudiana Rafhani Rosyidah Rini, Chylen S. Rofidah, Luthfiyah Salsabila Widya Kirana Siroj, Muhammad Said Agil SITI CHOLIFAH Siti Cholifah Sofi Rahayu, Bella Tri Chahyani Rahmawati Putri Tri Linggo Wati Vanda Rezania Veronika Oktaruliawan Wakhidah, Kemil Widyaningrum, Leni Yuroh Yuli Astutik Zulfida Ainindiyah Putri Purwanto Zurrotul Ilmiyah