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Journal : Magna Neurologica

Cognitive Function Analysis Using Telephone-Moca On Resident With Post Covid-19 Infection In Dr. Moewardi Hospital 2020-2021 Sudarman, Befrie Mahaztra; Danuaji, Rivan
Magna Neurologica Vol. 1 No. 1 (2023): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v1i1.450

Abstract

Introduction: Individuals after Covid-19 infection are suspected to have symptoms of cognitive impairment. Researchers wanted to use the telephone version of MoCA-22 assessment to assess cognitive function. Method: Cross-sectional study at Dr. Moewardi Hospital, Surakarta. Researchers assessed cognitive function telemedicine using Telephone-MoCA 22 and then compared it with the 30-point standard MoCA-INA examination. The analysis is continued on the results of inspection of each component. Results: During 2020-2021 there were 191 Residents who were infected with Covid-19. After screening, 69 people were able to complete the study, of which 34 people with a history of Covid-19 infection (49,2%) and 35 people (50,8%) without a history of Covid-19 infection. The subjects consisted of 34 men (49,2%); 35 women (50,8%); age range 25-33 (±28.97) years; Education grade is 28 juniors, 27 intermediate, and 17 seniors Resident. In the regression test, it was found that effect of Covid-19 history on cognitive function with p-value = 0,94 if using MoCA 30, and p-value = 1,17 if using T-MoCA 22. Comparative test of the two assessments obtained p-value = 0.475. In the analysis of each component obtained less than the maximum value on components of calculation, repetition and delayed memory. Conclusion: In the study, it was found that a history of Covid-19 infection had no effect on cognitive function in research subjects tested using MoCA-INA or Telephone-MoCA. T-MoCA examination has a test value that is not significantly different from the full version of MoCA 30 points.
The Effectiveness of Transcranial Magnetic Stimulation in Post Stroke Dysphagia: A Case Report Ginting, Suska Lara; Hambarsari, Yetty; Danuaji, Rivan; Hamidi, Baarid Luqman
Magna Neurologica Vol. 2 No. 1 (2024): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v2i1.942

Abstract

Background: A 72-year-old male, experiencing dysphagia and left-sided weakness for six months post-stroke, encountered challenges such as coughing and choking during the consumption of liquids and soft foods, along with a prolonged meal-swallowing process. Magnetic Resonance Imaging (MRI) revealed bilateral thrombotic infarction and left lateralization. Case: The Gugging Swallowing Screening Scale (GUSS) assessment demonstrated severe impairment with a total score of 7, persisting despite conventional physiotherapy attempts to improve swallowing function. Subsequently, repetitive transcranial magnetic stimulation (rTMS) was implemented, involving high-intensity stimulation in the ipsilesional hemisphere and low-intensity stimulation in the contralesional hemisphere. Remarkably, one-month post-rTMS, the patient displayed significant progress, evidenced by an improved GUSS score of 15, indicating enhanced swallowing function. Discussion: This case emphasizes the positive impact of bilateral rTMS hemispheric stimulation on post-stroke dysphagia. The strategic application of high-intensity ipsilesional and low-intensity contralesional stimulation emerged as an effective intervention for alleviating swallowing difficulties. Conclusion: These findings highlight the potential of rTMS as an innovative therapeutic approach for persistent dysphagia following a stroke. Repetitive transcranial magnetic stimulation (rTMS) has shown significant potential as an innovative and effective therapeutic approach for managing persistent post-stroke dysphagia. This case highlights the role of tailored rTMS protocols in improving swallowing function, with recovery influenced by factors such as stroke severity, dysphagia severity, age, nutritional status, timing of intervention, and lesion location.
Cell Based Treatment for Spinocerebellar Ataxia: A Clinical Case Report Damar Dyah Mentari; Rivan Danuaji
Magna Neurologica Vol. 4 No. 1 (2026): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v4i1.2412

Abstract

Background: Spinocerebellar ataxia (SCA) is a dominant and monogenic central nervous system disorder, characterized by progressive motor disorders affecting coordination, balance, speech, and ADL. The prevalence is 2.7 out of 100,000 people. Currently, cell-based therapy is being developed for clinical improvement in SCA. Case: A 48-year-old woman with weakness in both legs and arms, difficulty walking, dysmetria, and dysarthria since 2015. Examination of SARA scoring is severe ataxia, EMG showed polyradiculopathy, muscle denervation, and suspicion of posterior ramus lesions; complete blood laboratory and tumor markers were routine. MRI brain contrast and whole spine contrast radiology imaging were also performed. Clinical improvement was achieved in 2016 following stem cell injection in Thailand (dose and type of cells unknown). However, clinical worsening occurred from 2020 to 2024. The patient received Umbilical Cord Mesenchymal Stem Cells (MSC) in October 2024, administered intrathecally at a dose of 20 million cells. Discussion: The first injection showed significant clinical improvement. The second injection showed no clinical improvement, but no worsening of symptoms was found. The difference in results may be due to variations in the route of administration, cell type, cell quality, and the dose administered. Conclusion: The administration of umbilical cord mesenchymal stem cells (UC-MSCs) in SCA is considered safe, with minimal complications, and can suppress disease progression, although it does not produce clinical improvement.