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All Journal International Journal of Integrated Health Sciences Majalah Kedokteran Bandung Althea Medical Journal Global Medical and Health Communication Sari Pediatri Paediatrica Indonesiana Jurnal Ilmu Keperawatan dan Kebidanan
Sri Endah Rahayuningsih
Departemen Ilmu Kesehatan Anak, Fakultas Kedokteran, Universitas Padjadjaran, Bandung
Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Optic nerve sheath diameter and severity of central nervous infection Dewi, Anggun Puspita; Lukmanul Hakim, Dzulfikar Djalil; Rahayuningsih, Sri Endah; Risan, Nelly Amalia; Ghrahani, Reni; Adrizain, Riyadi
Paediatrica Indonesiana Vol. 63 No. 5 (2023): September 2023
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi63.5.2023.411-7

Abstract

Background Central nervous system (CNS) infection affects the brain, and can cause cerebral edema, increased intracranial pressure (ICP), cerebral herniation, and death. Measurement of the optic nerve sheath diameter (ONSD) by ultrasound is a new, non–invasive examination to predict ICP, with high sensitivity and specificity.Objective To analyze for a possible association between ONSD measured by ultrasonographic examination and severity of CNS infection. Methods This cross–sectional study was performed in the Pediatric Department of Hasan Sadikin Hospital, Bandung, West Java. Subjects were chosen by consecutive sampling. We measured ONSD, examined clinical manifestations, as well as performed a cerebrospinal fluid (CSF) study and imaging of CNS infection. Data analysis was done by paired T–test and one–way ANOVA, followed by Tukey test on significant variables. Results Subjects consisted of 32 children with CNS infection. The most common clinical symptoms were fever, decreased consciousness, and nuchal rigidity. Bivariate analysis revealed strong positive associations between ONSD and Glasgow Coma Scale (GCS), increased protein levels in CSF, and type of CNS infection. Conclusion Larger ONSD is significantly associated with lower GCS, increases CSF protein, and particular CNS infections. The ONSD is also associated with meningitis tuberculosis grade III, with a higher mean ONSD of both eyes compares to other CNS infections. Hence, the higher the ONSD, the more severe the degree of CNS infection.
STATUS SOSIAL EKONOMI DENGAN LAMA MENYUSUI Islami Islami; Herman Susanto; Sri Endah Rahayuningsih
Jurnal Ilmu Keperawatan dan Kebidanan Vol 4, No 1 (2013): JURNAL ILMU KEPERAWATAN DAN KEBIDANAN
Publisher : Universitas Muhammadiyah Kudus

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Abstract

Status sosial ekonomi merupakan salah satu faktor yang berkontribusi pada status kesehatan seseorang. Masyarakat dengan pendidikan dan sosial ekonomi yang rendah cenderung tidak memprioritaskan perilaku sehat seperti perilaku pencegahan penyakit, perilaku pemeliharaan kesehatan dan perilaku mencari pengobatan, termasuk perilaku pemberian ASI. Penelitia ini bertujuan untuk mengetahui korelasi status sosial ekonomi dengan lama menyusui. Metode penelitian ini adalah penelitian analitik dengan pendekatan observasional cross sectional. Populasi dalam penelitian ini adalah ibu menyusui di kecamatan Kaliwungu, Kota, Dawe, Jekulo dan Undaan Kabupaten Kudus yang memenuhi kriteria inklusi dengan teknik pengambilan sampel gugus bertahap dan diperoleh 140 responden. Penelitian ini dilaksanakan pada bulan Juli sampai September 2012. Data yang telah dikumpulkan dianalisis statistik univariabel, bivariabel dengan uji korelasi Lambda. Penghasilan dinilai berdasarakan jumlah biaya pengeluaran per bulan. Hasil yang diperoleh dalam penelitian ini adalah terdapat korelasi antara penghasilan dengan lama menyusui (r =0.393  p= 0.001), tidak terdapat korelasi antara pendidikan  dengan lama menyusui (r = 0.075 p= 0.180) dan tidak terdapat korelasi antara pekerjaan dengan lama menyusui ( r = 0.047 p= 0.249). Simpulan dalam penelitian ini adalah  tingkat pendidikan dan pekerjaan tidak memengaruhi lama menyusui, sedangkan penghasilan yang tinggi membuat ibu tidak mempunyai waktu yang cukup untuk menyusui.
Early Left Ventricular Structural Changes With Preserved Function in Overweight and Obese Adolescents: A Speckle-Tracking Echocardiography Study Nurfandi, Wendi; Hafsah, Tisnasari; Rahayuningsih, Sri Endah; Apandi, Putria Rayani; Hakim, Dzulfikar Djalil Lukmanul; Ghrahani, Reni; Kuswiyanto, Rahmat Budi; Gurnida, Dida Akhmad
Althea Medical Journal Vol 12, No 4 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v12n4.4343

Abstract

Background: Overweight and obesity in adolescents are associated with dyslipidemia and may contribute to early cardiovascular remodelling. Speckle-tracking echocardiography (STE) is a sensitive imaging technique capable of detecting early myocardial functional alterations before the onset of clinical symptoms. This study aimed to evaluate the correlation between cardiac chamber dimensions, left ventricular (LV) geometry and function, and lipid profiles in overweight and obese adolescents. Methods: A cross-sectional study was conducted from June to September 2023, involving 51 overweight and obese adolescents aged 15–18 years in Bandung, Indonesia. Anthropometric measurements, fasting lipid profiles (triglycerides, total cholesterol, LDL, HDL), and transthoracic echocardiography were obtained. LV dimensions, LV mass index (LVMI), ejection fraction (EF), fractional shortening (FS), and global longitudinal strain (GLS) were assessed. Associations were analyzed using Pearson correlation.Results: Participants were predominantly male (64.7%) with a mean age of 16.3±0.6 years. Overweight (47.1%) and obesity (52.9%) were almost equally distributed with a mean BMI of 29.6±4.1 kg/m². LVMI correlated negatively with total cholesterol (r=−0.356; p=0.005), HDL (r=−0.351; p=0.006), and LDL (r=−0.280; p=0.023). The LV posterior wall thickness and LV end-diastolic diameter were also inversely correlated with selected lipid parameters. Interventricular septal thickness in systole correlated positively with triglycerides (r=0.270; p=0.028). No significant correlations were found between lipid profiles and LV function parameters, including EF, FS, and GLS (p>0.05).Conclusions: In overweight and obese adolescents, lipid profiles are associated with early alterations in LV structural dimensions while LV systolic function remains preserved. These findings support the importance of early cardiovascular screening and lifestyle modification to reduce future cardiometabolic risk.
Left Ventricular Function in Steroid-Resistant Nephrotic Syndrome At Dr. Hasan Sadikin Hospital Kusumaputri, Aghnia Ghassani; Rahayuningsih, Sri Endah; Rossanti, Rini; Apandi, Putria Rayani; Widiasta, Ahmedz
Majalah Kedokteran Bandung Vol 57, No 4 (2025)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v57.4406

Abstract

Steroid-resistant nephrotic syndrome (SRNS) is a nephrotic syndrome (NS) which does not respond to high-dose corticosteroid therapy after 4 to 8 weeks. SRNS occurs in approximately 10–20% of childhood idiopathic nephrotic syndrome. SRNS patients are at risk of developing cardiovascular complications due to the long duration of the disease. This retrospective descriptive study investigated left ventricular function in pediatric patients with steroid-resistant nephrotic syndrome (SRNS) at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, from 2018 to 2022. A total of 42 patients aged 1 month to 18 years who underwent transthoracic echocardiography (TTE) were included. Left ventricular function was assessed using ejection fraction (EF) and fractional shortening (FS). Most patients (61.9%) had normal EF and FS values, while 38.1% showed decreased systolic function. The mean EF and FS were 55.8% and 30.2%, respectively, with median values of 59.3% and 31.2%. An important finding in this study is that some children with SRNS exhibited decreased EF and FS values despite having no other identifiable risk factors for ventricular dysfunction, such as congenital heart disease (CHD), rheumatic heart disease (RHD), chronic kidney disease (CKD), or hypertension. This finding sugest that ventricular dysfunction may still occur independently in some cases of SRNS.
Co-Authors Adrizain, Riyadi Ahmedz Widiasta Amani Sakinah Augiani Anggia Farrah Rizqiamuti Anggraini Alam Anggraini Alam Anggraini Alam Armijn Firman Armijn Firman Armijn Firman Armijn Firman, Armijn Atika Zahria Arisanti Augiani, Amani Sakinah Benny Hasan Purwara Carla Pusparani Cissy Sudjana Prawira Dani Kurnia Dany Hilmanto Dedet Hidayat Dedi Rachmadi Dedi Rachmadi Dewi Marhaeni Diah Herawati Dewi, Anggun Puspita Dida Akhmad Gurnida Dinna Meinardaniawati Djatnika Setiabudi Dwi Prasetyo Dzulfikar Djalil Lukmanul Hakim Eddy Fadlyana Erliana Ulfah Fathiyah Ma’ani Hadyana Sukandar Haruka Hamanoue Heda Melinda Nataprawira Henry Leo Herman Susanto Herry Garna Herry Herman Ina Rosalina Ineu Nopita Irvan Afriandi Islami - Islami Islami Islami, Islami Julistio Djais Keumala Hayati Keumala Hayati Kusumaputri, Aghnia Ghassani Nanan Sekarwana Naomichi Matsumoto Nelly Amalia Risan, Nelly Amalia Nicholas Adrian Nono Sumarna Nono Sumarna Afandi Nurfandi, Wendi Putria Rayani Putria Rayani Apandi Putria Rayani Apandi, Putria Rayani Queen Khoirun Nisa Mairo, Queen Khoirun Rachmat Budi Rahmat Budi Rahmat Budi Kuswiyanto Rahmat Budi Kuswiyanto, Rahmat Budi Reby Kusumajaya Reni Ghrahani Riri Adriana Rizki Ayu Rizal Rossanti, Rini Rully Marsis Amirullah Roesli Shinta Larasaty Sjarif Hidajat Effendi Sri Sudarwati Susiarno, Hadi Syahradian Hasbrima Tan Siauw Koan Thiban Raj Manoraj Tisnasari Hafsah, Tisnasari Tommy Nugrahadi Whisnubrata Tono Djuwantono Tubagus Ferdi Fadilah, Tubagus Ferdi Uni Gamayani Vidi Permatagalih Villia Damayantie Wiwin Winiar Yanti Mulyana Yulia Sofiatin Yunita Sinaga