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All Journal International Journal of Integrated Health Sciences Majalah Kedokteran Bandung Althea Medical Journal Global Medical and Health Communication MNJ (Malang Neurology Journal) Journal of Medicine and Health Journal of Indonesian Dental Association Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Cermin Dunia Kedokteran Jurnal Neuroanestesi Indonesia OKTAL : Jurnal Ilmu Komputer dan Sains Buletin Ilmiah Ilmu Komputer dan Multimedia (BIIKMA) Neurona Journal of Medicine and Health

Lisda Amalia

Department Of Neurology, Faculty Of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung

Author-ID : 2503958

Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Dentistry Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Characteristics of Cardioembolic Stroke Patient in Neurologic Ward Dr. Hasan Sadikin General Hospital Bandung Adriana Damayanti; Lisda Amalia; Reza W. Sudjud
Journal of Medicine and Health Vol. 2 No. 1 (2018)
Publisher : Universitas Kristen Maranatha

Stroke is the second most common cause of death worldwide after heart disease. About80% stroke cases are ischemic stroke. One of 4 people with ischemic stroke had cardioembolicstroke. Ninety percent of cardiac emboli obstruct cerebral blood vessels and causedneurological deficit. Cardioembolic stroke may be due to abnormalities in cardiac walls,rhythm, valve, or function. Stroke patients with cardiac abnormalities have poor prognosis. Thisretrospective descriptive study was done in May-June 2017. We collected 103 medical recordsof stroke patients from Department of Neurology, Dr. Hasan Sadikin General Hospital duringJanuary 2015- March 2016. Data regarding sex, age, education level, economic status, andcardiac abnormalities were recorded. Majority of subjects were female (53.4%). The mostfrequent age group was 45-65 years old (49.51%). Most subjects had low educational level(76.7%) and low economic status (77.67%). Among subjects, 41.75% had cardiac rhythmabnormalities, 29.13% had cardiac wall abnormalities, 14.56% had cardiac valveabnormalities, and 14.56% had cardiac function abnormalities. The most common cause ofcardioembolic stroke was atrial fibrillation.Keywords: cardioembolic stroke epidemiology, patient characteristics, cardiac disease

Clinical Profile of Stroke Patients with Vertigo in Hasan Sadikin General Hospital Bandung Neurology Ward Amany Khansa; Aih Cahyani; Lisda Amalia
Journal of Medicine and Health Vol. 2 No. 3 (2019)
Publisher : Universitas Kristen Maranatha

Vertigo often occurs from the ages of 18 to 79 years with a prevalence of 7.4%. Central vertigo is less common than peripheral vertigo, but it can worsen disability in stroke patients. This study aims to determine the profile of stroke patients with vertigo in Hasan Sadikin General Hospital Bandung Neurology Ward. This is a retrospective descriptive study, using medical record data from 2013 to 2017, and collected 173 medical record data. The results showed that most stroke patients with vertigo were women (59%), the most age group was 55-64 years (34.1%), the most common type of stroke was ischemic stroke (75.7%), the most disturbance regarding the vertebrobasilar system was (72.8%), the most patients got the first stroke was (52.6%), 60.7% of patients suffered from hypertension, 23.1% of patients suffered from hyperlipidemia 40 (23.1%), and 22% of patients suffered from diabetes mellitus type 2. This study concludes that stroke patients who experience vertigo are more common in women, and in the 55-64 year age group. The most common stroke is ischemic in the vertebrobasilar system. Most symptoms in stroke patients with vertigo are dizziness not affected by position, vomiting and nystagmus. Hypertension, hyperlipidemia and diabetes mellitus play an important role in the incidence of stroke in patients. Keywords: vertigo, risk factor, stroke, vertebrobasilar

THE LEVEL OF KNOWLEDGE AMONG UNDERGRADUATE MEDICAL STUDENTS ABOUT STROKE Rita Arsika Fauziah; Lisda Amalia; Nandina Oktavia; Lulu Eva Rakhmilla
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 11, No 2 (2022): JUNI
Publisher : Asosiasi Institusi Pendidikan Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.67942

Background: Stroke is a neurological emergency that requires prompt and precise diagnosis and treatment. However, errors in diagnosis and treatment are still frequently seen. One of the main causes of this problem is the lack of doctors’ knowledge. This study aims to determine the level of knowledge among undergraduate medical students about stroke. The results of this study can be used as basic information to provide educational interventions to medical students to prevent and minimize the occurrence of medical errors. Methods: This study used a quantitative-descriptive method with a cross-sectional approach. The study subjects were third-semester medical undergraduate students at the Medical Faculty of Padjadjaran University during the 2018/2019 academic year. Samples were 43 secondary data collected from ischemic and hemorrhagic stroke Students Objective Oral Case Analysis (SOOCA) exam scores and 168 primary data collected using a 30-item questionnaire regarding stroke knowledge. The data obtained was then analyzed descriptively and the result was categorized into 3 levels of knowledge: Good, moderate, and poor. Results: Each variable demonstrates a varying degree of knowledge. However, based on the total scores and averages collected from both the questionnaire and the SOOCA exam, most of the students had a moderate level of knowledge regarding ischemic and hemorrhagic stroke. Conclusion: Most of the students had a moderate level of knowledge about stroke, so educational interventions and student’s capabilities improvement are required to increase knowledge of stroke.

Hypoxia Inducible Factor (HIF) 1-Α dan Vascular Endothelial Growth Factor (VEGF) pada Stroke Iskemik Fase Akut Lisda Amalia; Ida Parwati; Ahmad Rizal; Ramdan Panigoro; Uni Gamayani; Al Rasyid; Nur Atiik
Jurnal Neuroanestesi Indonesia Vol 8, No 3 (2019)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Stroke iskemik merupakan salah satu penyebab stroke tersering, disebabkan oleh oklusi pembuluh darah serebral dan penyebab kematian ketiga. Saat awitan stroke iskemik terjadi, area otak yang diperdarahi oleh pembuluh darah akan kekurangan oksigen dan nutrisi sehingga sel otak terutama neuron berada dalam risiko, neuron ini masih dapat berfungsi yang dikenal sebagai penumbra. Hipoksik, salah satu karakteristik penumbra merupakan stimulus utama regulasi protein HIF-1α. Hipoksik sendiri merupakan stimulus utama prekondisi iskemik. Prekondisi iskemik akan menghasilkan fenotipe tahan hipoksia yakni protein hypoxia inducible factor (HIF)-1α. HIF-1α merupakan satu-satunya zat yang dikeluarkan oleh jaringan yang mengalami hipoksia. HIF-1α bertindak sebagai protein sinyal yang dapat meregulasi gen protein lain. Efektor HIF-1α antara lain eritropoitin dan vascular endothelial growth factor (VEGF). Pertumbuhan, diferensiasi dan ketahanan sel endotel diregulasi oleh VEGF yang distimulasi dari HIF-1α. Selama iskemik serebral, jaringan yang rusak mencoba untuk meningkatkan pengiriman oksigen melalui induksi angiogenesis melalui produksi VEGF. Hal ini ditandai dengan adanya peningkatan jumlah pembuluh-pembuluh darah mikro di area infark. VEGF dan reseptornya diregulasi oleh HIF-1α dalam hari pertama iskemik.Hypoxia Inducible Factor (HIF) 1-Α and Vascular Endothelial Growth Factor (VEGF) in Acute Ischemic StrokeAbstractIschemic stroke is one of the most common causes of stroke, caused by cerebral vascular occlusion and the third cause of death. When the onset of an ischemic stroke occurs, the area of the brain bleeding by blood vessels will lack oxygen and nutrients so that brain cells, especially neurons, are at risk, these neurons can still function known as penumbra. Hypoxic, one of the characteristics of penumbra is the main stimulus for regulation of HIF-1α protein. Hypoxia itself is the main stimulus of ischemic precondition. The ischemic precondition will produce a hypoxic-resistant phenotype namely protein hypoxia inducible factor (HIF) -1α. HIF-1αis the only substance released by tissue that experiences hypoxia. HIF-1α acts as a signaling protein that can regulate other protein genes. Effectors of HIF-1αinclude erythropoitin and vascular endothelial growth factor (VEGF). Growth, differentiation and endurance of endothelial cells are regulated by VEGF stimulated from HIF-1α. During cerebral ischemia, damaged tissue tries to increase oxygen delivery through induction of angiogenesis through VEGF production. This is characterized by an increase in the number of micro blood vessels in the infarct area. VEGF and its receptors are regulated by HIF-1α in the first day of ischemia.

Stroke pada Usia Muda Andi Basuki Prima Birawa; Lisda Amalia
Cermin Dunia Kedokteran Vol 42, No 10 (2015): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v42i10.955

Hampir 10% stroke terjadi pada usia relatif muda (kurang dari 45 tahun). Angka kejadian stroke pada usia di bawah 45 tahun diperkirakan 7 – 15 kasus/100.000 penduduk/tahun dan lebih jarang pada kelompok anak-anak, yaitu 1 – 8 kasus/100.000/tahun. Faktor risiko terjadinya stroke pada usia muda berbeda-beda, antara lain: (1) Migren, (2) Sickle-cell disease, (3) Penyakit jantung, (4) Abnormalitas pembuluh darah serebral, (5) Focal cerebral arteriopathy of childhood (FCA), (6) Ensefalopati pasca-varisela, (7) Mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS), (8) Diseksi arteri, (9) Penyalahgunaan obat, (10) Vaskulitis serebral seperti arteritis temporal, arteritis Takayasu, polyarteritis nodosa (PAN), Wegener’s granulomatosis, (11) Systemic lupus erythematosus (SLE), (12) Cerebral autosomal dominant arteropathy with subcortical infarcts and leucoencephalopathy (CADASIL), (13) Fabry’s disease, dan (14) Trombofilia. Khusus pada wanita usia muda, beberapa faktor risiko lainnya antara lain: (1) Penggunaan kontrasepsi oral terutama pada wanita perokok, migren dengan aura, dan hipertensi; (2) Kehamilan, terutama jika terdapat preeklampsi, eklampsi, dan sindrom HELLP (hemolysis, elevated liver enzymes, and low platelets). Stroke pada usia muda memiliki karakteristik tersendiri, sehingga membutuhkan pendekatan yang berbeda. Faktor risiko perlu diidentifikasi untuk penatalaksanaan dan pencegahan terjadinya stroke berulang. Penelitian berbasis populasi dengan metodologi yang baik penting untuk lebih mengetahui besaran masalah stroke pada usia muda.Nearly 10 % strokes occur at a relatively young age (less than 45 years old). The incidence of stroke in under 45 year-old is between 7-15 cases/100,000 persons/year and 1-8 cases /100,000/year in children. Disorders or diseases related or suspected as risk factors are: (1) Migraine, (2) Sickle - cell disease, (3) Heart disease, (4) Cerebral blood vessels abnormality,

THE DISEASE PATTERN OF ELDERLY PATIENTS ADMITTED IN THE NEUROLOGY WARD OF HASAN SADIKIN GENERAL HOSPITAL Millata Azma Basmala; Cep Juli; Paulus Anam Ong; Nushrotul Lailiyya; Lisda Amalia
MNJ (Malang Neurology Journal) Vol. 9 No. 1 (2023): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2023.009.01.3

Background: As life expectancy continues to increase, the elderly population in Indonesia has significantly doubled in the last five decades, making Indonesia a home to 4th largest population of elderly people in Asia. Unlike other age group, there are more challenges in handling older persons due to their increased mortality, morbidity, and disability risks. Objective: We performed this study to understand the disease pattern in elderly patients admitted in the neurology ward of Hasan Sadikin General Hospital. Methods: This was a descriptive cross-sectional study using data from medical resume. We included medical resume of elderly patients admitted in the neurology ward of Hasan Sadikin General Hospital from January 2015 to December 2019. All incomplete, lost, or inaccessible medical resumes were excluded. Results: Among a total of 400 subjects, 210 (52.5%) were males and 190 (47.5%) were females. Young old (59,5%) presented to be the most observed age group. The most frequent diseases of elderly patients seen in this study were ischemic stroke (55.3%), followed by hemorrhagic stroke (19.5%), subarachnoid hemorrhage (5.3%), and tetanus (4.5%). Atherothrombotic subtype (50,6%) of ischemic stroke was seen to be the most frequent. Conclusion: Noncommunicable diseases were the majority of all cases in the elderly with cerebrovascular diseases, such as stroke and subarachnoid haemorrhage, as the most common conditions. It is important to develop efficient hospital-based management strategies particularly for these diseases and intensify early detection and management of risk factors.

CLINICAL OUTCOME OF STROKE PATIENTS BASED ON THE NATIONAL INSTITUTES OF HEALTH STROKE SCALE (NIHSS) IN A TERTIARY HOSPITAL Liunardo Bintang Pratama; Lisda Amalia; Cep Juli; Uni Gamayani; Asep Nugraha Hermawan
MNJ (Malang Neurology Journal) Vol. 9 No. 1 (2023): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2023.009.01.4

Background: Stroke is the second leading cause of death and the third cause of disability globally. Clinical outcomes caused by stroke are varied and influenced by various factors. Objective: This study aims to describe the clinical outcome of stroke patients based on neurological deficit using NIHSS at Dr. Hasan Sadikin General Hospital, Bandung. Methods: This study is a retrospective descriptive, cross-sectional study using secondary data from medical records recruited between January 2019 – December 2019 at the Department of Neurology Dr. Hasan Sadikin General Hospital Bandung with the total sampling method. Variables include demographic data, risk factors, and clinical characteristics. Neurological deficit was assessed using NIHSS. Data were analyzed and presented in the form of tables. Results: There were 202 subjects eligible for this study, including ischemic (71.8%) and intracerebral hemorrhage (28.2%) stroke patients. Most of the subjects were male (53%), aged ≥60 years (50,5%), presenting with onset >6 hours (72.3%), and had hypertension (92,1%). Most of the subjects have a moderate stroke (n=102;50.5%) based on the NIHSS score at admission and mild stroke (n=117;57.9%) based on the NIHSS score at discharge, with a motor deficit as the most common neurological deficit found. Conclusion: The majority of stroke patients presented with a moderate stroke on admission and had a clinical improvement during hospital treatment, with most of the patients experiencing a mild stroke on discharge based on NIHSS score. The motor deficit is the most common neurological deficit that affects clinical outcomes.

Characteristics and Risk Factors of Patients with Acute Ischemic Stroke in Dr. Hasan Sadikin General Hospital Bandung, Indonesia Nesyia Tara Restikasari; Uni Gamayani; Lisda Amalia; Sofiati Dian; Aih Cahyani
Althea Medical Journal Vol 9, No 4 (2022)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v9n4.2362

Background: Stroke is the second most common cause of death globally and the third most common cause of disability. The prevalence of stroke is increasing despite managing various stroke risk factors that have improved considerably. Ischemic stroke is the most prevalent type, and about 90% of stroke events are attributable to modifiable risk factors. This study aimed to explore the characteristics and risk factors of patients with acute ischemic stroke in Dr. Hasan Sadikin General Hospital.Methods: A descriptive cross-sectional study was conducted retrospectively in October 2020, using a total sampling method on medical records of acute ischemic stroke patients in Dr. Hasan Sadikin General Hospital year 2019. Medical records with incomplete and missing data were excluded. Demographic and known risk factors data were collected and presented in the table.Results: Of the 355 subjects, male patients (n=69, 76.7%) were predominant, with the age range of 55–64 years old (36.1%). The majority of the subjects had an ischemic stroke of large-artery atherosclerosis (68.2%) with carotid system involvement (93.2%). As much as 305 subjects (85.9%) had hypertension as the risk factor, followed by dyslipidemia (47.3%), heart disease (39.4%), previous stroke history (33.8%), smoking (25.6%), diabetes mellitus (24.5%), hyperuricemia (12.1%), and blood disorders (2.3%).Conclusions: Males in the older age group have a higher risk of getting acute ischemic stroke with ischemic stroke of large-artery atherosclerosis and carotid system involvement, and hypertension has the highest prevalence.

Sistem Pakar Penyakit Lambung Menggunakan Metode Forward Chaining Ardiana; Lisda Amalia; Muhammad Mustofa Ramadhan; Rizky Gimnastiar
Buletin Ilmiah Ilmu Komputer dan Multimedia Vol 1 No 1 (2023): Buletin Ilmiah Ilmu Komputer dan Multimedia (BIIKMA) INPRESS
Publisher : Shofanah Media Berkah

Show Abstract | Download Original | Original Source | Check in Google Scholar

This research aims to develop a system that can assist in identifying and diagnosing diseases based on symptoms experienced by humans, especially diseases of the stomach. The desiredsystem is an expert system that is able to imitate the thinking of an expert in diagnosing diseases. Expert system is a technology based on knowledge, facts, and reasoning, used to solve problems in various fields of science, including disease diagnosis. The development method used is the SLR (systematic Literature Review) method using the Forward Chaining inference method and the depthfirst search model using the Java programming language. This research uses a knowledge base consisting of seventeen symptoms and seven types of stomach diseases, including: Gastritis,Dyspepsia, Gastric Cancer, GERD, Gastroenteritis, Gastroparesis, and Peptic Ulcer. Dr. Amelia Mayangsari also conducted a feasibility study of this system, and the results showed that this expert system has a diagnostic accuracy rate of 75% and can be categorized as good. However, improvements are still needed in terms of effectiveness and completeness of information.

COMPARISON OF COGNITIVE FUNCTION BETWEEN FIRST ISCHEMIC STROKE AND RECURRENT ISCHEMIC STROKE PATIENTS Rizkia, Fildza Intan; Calista, Chandra; Gunadharma, Suryani; Hermawan, Asep Nugraha; Amalia, Lisda; Ong, Paulus Anam
MNJ (Malang Neurology Journal) Vol. 8 No. 1 (2022): January
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2022.008.01.7

Background: Cognitive impairment is a common condition that may affect up to 50% of stroke patients. Post stroke cognitive impairment is associated with reduced quality of life, which may increase the number of dependency. Recurrent stroke may happen in approximately 25% patients and they have higher rates of cognitive impairment.Objective: The aim of this study is to examine the comparison of cognitive function between first ischemic stroke and recurrent ischemic stroke patients in Hasan Sadikin Hospital, Bandung.Methods: This study is a retrospective, cross-sectional study using the data recruited between the year 2012 - 2016 at the Department of Neurology at the Hasan Sadikin Hospital Bandung. The data collected in this study were demographic data, including age, level of education, and residence, and the clinical data as well. Cognitive function was assessed using Mini-Mental State Examination (MMSE). The comparison between the cognitive function between both groups were analyzed using the Mann-Whitney U test.Results: There were 428 subjects eligible for this study, with 207 subjects categorized as first ischemic stroke group and 221 subjects categorized as recurrent ischemic stroke group. There was a statistically significant difference in MMSE scores between the first ischemic stroke patients (24.90 Â± 4.64) and recurrent ischemic stroke patients (22.85 Â± 4.64 ) with a p value of 0.002.Conclusion: Recurrent ischemic stroke patients had lower MMSE scores than the first ischemic stroke patients. Clinicians should be more aware in detecting early cognitive impairment in stroke patients and in preventing the incidence of recurrent stroke.

Co-Authors Adriana Damayanti Afdi Arahim Putra Agnes Rengga Indrati Agus Susanto Ahmad Rizal ahmad rizal Ahmad Rizal Ganiem, Ahmad Rizal Aih Cahyani Al Rasyid Amanda Diannisa Azzahra Amany Khansa Amaylia Oehadian Anam Ong Andi Basuki Prima Birawa Andi Basuki Prima Birawa Andi Basuki Prima Birawa Andre Tanuwijaya, Andre Ardiana Arviana Adamantina Putri Asep Nugraha Hermawan Asep Nugraha Hermawan Ayu, Auliya Putri Badriyah, Nur’aini Jamilatul Berliana, Sobaryati Biben, Vitriana Calista, Chandra Cep Juli Chandra Calista Dewi Yulianti Bisri Eppy Buchori Fifi Veronica Fitri Yanti Gaga Irawan Nugraha Gloria Kartika Gunadharma, Suryani Guntur Darmawan Hanna Goenawan Hermawan, Asep Nugraha Hidayat, Faqih Hidayat, Shaffana Hilman Hilman Ida Parwati Islami, Aditya Iwan Fuadi Kartika, Gloria Khairunnisa, Shafa Ayu Lailiyya, Nushrotul Laniyati Hamijoyo, Laniyati Lee Shok Chen Lee Shok Chen, Lee Shok Leni Lismayanti Liunardo Bintang Pratama Lulu Eva Rakhmilla Marina A. Moeliono Marina A. Moeliono, Marina A. Millata Azma Basmala Muhammad Mustofa Ramadhan Nandina Oktavia Nani Kurniani Nesyia Tara Restikasari Nur Atiik Nurmin, Rahmawati Nushrotul Lailiyya Ong, Paulus Anam Pandji Irani Fianza Paulus Anam Ong Paulus Anam Ong Ramdan Panigoro Reza W. Sudjud Ria Bandiara Rita Arsika Fauziah Rizkia, Fildza Intan Rizky Gimnastiar Saputra, Gilang Nispu Sari, Kartika Indah Shenny Dianathasari Santoso Sidabutar, Berliana Siti Aminah Siti Aminah Sobana Siti Nur Fatimah Sitorus, Trully Deti Rose Siuliyanty, Siuliyanty Sobaryati, Sobaryati Sofiati Dian Sukmawati, Rani Suryani Gunadharma Suwarman, S Suwarman, S Syifa, Nadia Syifa, Nadia Tiara Pramaesya Tiene Rostini, Tiene Togu, Glenn Mark Trislawati, Cristina Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani Uni Gamayani, Uni Wandira, Rega Dwi Wardhani, Ildzamar Haifa Wardoyo, Chandra Calista Yusuf Wibisono Yusuf Wibisono

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