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All Journal Jurnal Sains dan Seni ITS IPTEK The Journal for Technology and Science Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Indonesian Journal of Biotechnology AKSES: Jurnal Ekonomi dan Bisnis Jurnal Florea Journal of Tropical Biodiversity and Biotechnology Journal of Marine-Earth Science and Technology Sewagati English Language and Literature in Education Journal (ELLINE Journal) Medical-Surgical Journal of Nursing Research Syaikhuna: Jurnal Pendidikan dan Pranata Islam STAI Syaichona Moh. Cholil Bangkalan
Dewi Hidayati
Institut Teknologi Sepuluh Nopember
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Nursing Public Health Social Sciences Veterinary Other

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Journal : IPTEK The Journal for Technology and Science

 1 
An Evaluative Study on Sidoarjo Mud Flow after Phytoremediation Treatment in Milk Fish (Chanos Chanos) Liver Dewi Hidayati
IPTEK The Journal for Technology and Science Vol 21, No 4 (2010)
Publisher : IPTEK, LPPM, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j20882033.v21i4.51

Abstract

A sudden discharge of Sidoarjo mud flow into the water bodies would disturb aquatic biota, the fisheries culture. The aim of this research is to evaluate the availability of phytoremediated water of Sidoarjo mud flow (abbreviated: pwmf) as a milkfish culture media using liver histological approach. After two weeks acclimatization period, the juvenile and adult of milkfish were exposed the pwmf at the sub lethal concentration and an acute static bioassay at 96 hours. Control fishes were reared in the artificial brackish water. Each treatment of pwmf exposure was done in three replicates. After exposure, the liver fishes were removed and histologically processed using paraffin method and HE staining. Histopathology change was assessed semi quantitative scoring. The result of the histological analyses suggested the liver pathological features such as vacuolation of hepatocytes, the loss of sinusoid integrity from mild to severe occurrence and necrosis.
Histology of Mice Skin Tissue Based on in Vivo Evaluation of the Anticancer Extracts of Marine Sponge Aaptos Suberitoides Awik Puji Dyah Nurhayati; Dewi Hidayati; Rarastoeti Prastiwi; Sitarina Widyarini; Sukardiman Sukardiman; Wijayanti Pujitono
IPTEK The Journal for Technology and Science Vol 22, No 1 (2011)
Publisher : IPTEK, LPPM, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j20882033.v22i1.88

Abstract

The sponge Aaptos suberitoides can produce high secondary metabolite with some farmocological activities as antimicrobial, antiviral, antiinflamatory, and anticancer agents. The purpose of this research is to find out correlations between activities of the etanol extracts of marine sponges Aaptos suberitoides on the cancer growth of subcutaneous mice (Mus musculus) injected by Benzo(a)piren. For the purpose the mice were divided into six groups, i.e. I, II, III, IV, V, and VI. Each group was treated with carcinogenic inductions by intravenously injecting the Benzo(a)piren concentration of 0.3g/0.2 ml oleum olivarum. After the cancer was appeared at the fifteenth day, the mice were treated by the anticancer extracts of marine sponges Aaptos suberitoides with concentrations of 500 mg/kg BB (Group IV), 1000 mg/kg BB (Group IV), and 1500 mg/kg BB (Group IV). The treatments were orally done each day for two weeks. At the twentieth week, subcutaneous cancer tissues were taken to make histological preparates using a parafin method. Result of the histological observation indicates that cancer in the mice was fibrosarcoma characterized by the thickening dermis layers, necrosis, mitosis, and nuclear polymorphsm. Necrosis, mitosis, and nuclear polymorphism occurred in Groups II, IV, V, and VI, and did not in Groups I and II. Presentation of necrosis was 20-60%, mitosis was in 3-4 cells, and nuclear polymorphism was 100%. Result of the statistical analyses by using the Kruskal-Wallis method and the Pair Comparison test indicates that the anticancer extracts of marine sponges with the concentrations of 500 mg/kg BB, 1000 mg/kg BB, and 1500 mg/kg BB had no activity inducing mice skin cancer.
Co-Authors Achmad Fauzi Afrilya Dina Salsabila Alifia Cahyaning Putri Anak Agung Gede Sugianthara Anies Wijayanti Anies Wijayanti Aulia Istighfarotunnisa Aunurohim Aunurohim Awik Pudji Diah Nurhayati Awik Puji Dyah Nurhayati Bahruddin Salam Danang Samudra Devi Pramesti Wulandari Didit Prasetyo Dini Adni Navastara, Dini Adni Dwi Oktafitria Edwin Setiawan Eko Purnomo Enny Zulaika Enny Zulaika Farid Kamal Muzaki Fauziah F Fitria, N. Yeni Geoloveriana Esasi Hani Sirine Hermawan Hermawan Hermawan Iska Desmawati Kamila Islamiati Kharisma Armida Ulayya Kristianto Kristianto Kuntum Febriyantiningrum Lanny Kartikasari Lissa Rosdiana Maitsa Adzro Fania Marita Ika Joesidawati Millah, Ro’iqotul N. Nurjannah Nadhila, Auliya Rahma Nadila Wulan Cahyani Natanael Hari Wijaya Nia Nurfitria Noor Nailis Sa'adah Noor Nailis Saadah Noor Nailis Sa’adah Nova Maulidina Ashuri Nur Syahroni Nurjannah N, Nurjannah Nurlita Abdulgani Nurlita Abdulgani Nurul Jadid Oktafitria, Dwi Rahmadani, Syakirah Shafwah Rarastoeti Prastiwi Rony Irawanto Sa'adah, Noor Nailis Sabila Ghassani Salim Arrokhman Saptarini, Dian Shabrina Syifa Ghaissani Shinta Hartanto Shinta Hartanto, Shinta Shovitri, Maya Sri Wulandari Sukardiman Sukma, Nur Awaliyah Mentari Suwarsih S Tutik Nurhidayati Utami, Prastyo Rinie Budi Wijayanti Pujitono Yeyes Mulyadi Zufar Azzaria Azmi Zuwanita, Cyntya Sri